BR9808312A - Dispositivo de inalação - Google Patents

Dispositivo de inalação

Info

Publication number
BR9808312A
BR9808312A BR9808312-0A BR9808312A BR9808312A BR 9808312 A BR9808312 A BR 9808312A BR 9808312 A BR9808312 A BR 9808312A BR 9808312 A BR9808312 A BR 9808312A
Authority
BR
Brazil
Prior art keywords
flow path
inhalation
metering device
powder
inhalation device
Prior art date
Application number
BR9808312-0A
Other languages
English (en)
Inventor
Jan Andersson
Allan Dagsland
Kjell Wetterlin
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of BR9808312A publication Critical patent/BR9808312A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001Particle size control
    • A61M11/002Particle size control by flow deviation causing inertial separation of transported particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0005Details of inhalators; Constructional features thereof with means for agitating the medicament
    • A61M15/0006Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means
    • A61M15/0008Details of inhalators; Constructional features thereof with means for agitating the medicament using rotating means rotating by airflow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/0021Mouthpieces therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0065Inhalators with dosage or measuring devices
    • A61M15/0068Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/007Mechanical counters
    • A61M15/0071Mechanical counters having a display or indicator
    • A61M15/0076Mechanical counters having a display or indicator on a drum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0086Inhalation chambers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00Special media to be introduced, removed or treated
    • A61M2202/06Solids
    • A61M2202/064Powder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2206/00Characteristics of a physical parameter; associated device therefor
    • A61M2206/10Flow characteristics
    • A61M2206/16Rotating swirling helical flow, e.g. by tangential inflows

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Nozzles (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Manipulator (AREA)

Abstract

<B>"DISPOSITIVO DE INALAçãO<D>. A invenção proporciona um inalador para administração de pó mediante inalação, compreendendo: um caminho de fluxo definido por uma pluralidade de superfícies, através das quais uma corrente de ar é quando em uso extraída na inalação por um usuário, o caminho de fluxo incluindo uma embocadura (2) e um dispositivo de dosagem (18), para fornecimento de uma dose de pó ao caminho de fluxo para arraste da corrente de ar, caracterizado em que o inalador compreende ainda um elemento móvel a jusante do dispositivo de dosagem (18), para inibir o acúmulo de pó sobre uma superfície do caminho de fluxo, a jusante do dispositivo de dosagem (18).
BR9808312-0A 1997-03-14 1998-03-13 Dispositivo de inalação BR9808312A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9700937A SE9700937D0 (sv) 1997-03-14 1997-03-14 Powder inhaler I
PCT/SE1998/000465 WO1998041264A1 (en) 1997-03-14 1998-03-13 Inhalation device

Publications (1)

Publication Number Publication Date
BR9808312A true BR9808312A (pt) 2000-05-16

Family

ID=20406164

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9808312-0A BR9808312A (pt) 1997-03-14 1998-03-13 Dispositivo de inalação

Country Status (21)

Country Link
US (1) US6257232B1 (pt)
EP (1) EP0979115B1 (pt)
JP (2) JP4057066B2 (pt)
KR (1) KR100466998B1 (pt)
CN (1) CN100500238C (pt)
AR (1) AR020247A2 (pt)
AT (1) ATE233113T1 (pt)
AU (1) AU6431198A (pt)
BR (1) BR9808312A (pt)
CA (1) CA2283199C (pt)
DE (1) DE69811655T2 (pt)
DK (1) DK0979115T3 (pt)
ES (1) ES2191928T3 (pt)
HK (1) HK1029291A1 (pt)
NO (1) NO322447B1 (pt)
NZ (1) NZ337479A (pt)
PL (1) PL188855B1 (pt)
PT (1) PT979115E (pt)
SE (1) SE9700937D0 (pt)
WO (1) WO1998041264A1 (pt)
ZA (1) ZA982021B (pt)

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AU761307B2 (en) * 1997-03-14 2003-06-05 Astra Aktiebolag Inhalation device
SE9700938D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler II and a method of construction thereof
TW469832U (en) * 1997-03-14 2001-12-21 Astra Ab Inhalation device
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
PE20010819A1 (es) * 2000-01-10 2001-09-05 Procter & Gamble Dispositivo para la inhalacion de polvo seco
PT1142601E (pt) * 2000-04-07 2006-05-31 Andi Ventis Ltd Bocal para inalador de particulas
SI1163920T1 (en) 2000-06-13 2004-12-31 Andi-Ventis Limited Mouthpiece for a particulate inhaler
TWI224511B (en) * 2000-06-23 2004-12-01 Norton Healthcare Ltd De-agglomerator for breath-actuated dry powder inhaler
DE10040528A1 (de) * 2000-08-18 2002-02-28 Pari Gmbh Inhalationsvorrichtung und Verfahren zur Erzeugung eines Partikelnebels für Inhalationszwecke
US6681768B2 (en) * 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
JP3619176B2 (ja) * 2001-09-14 2005-02-09 オムロンヘルスケア株式会社 エアロゾル粒子分別装置及び吸入器
US6923175B2 (en) 2002-03-20 2005-08-02 Mannkind Corporation Inhalation apparatus
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PL1786784T3 (pl) 2004-08-20 2011-04-29 Mannkind Corp Kataliza syntezy diketopiperazyn
EP1791542B1 (en) 2004-08-23 2015-05-20 Mannkind Corporation Diketopiperazine salts for drug delivery
DE602005019604D1 (de) * 2004-11-10 2010-04-08 Cipla Ltd Inhalator
DK1928423T3 (en) 2005-09-14 2016-02-29 Mannkind Corp A method for drug formulation based on increasing the affinity of the active substances to the crystalline microparticle surfaces
CN101346158B (zh) * 2005-12-23 2012-02-22 阿斯利康(瑞典)有限公司 一种用于粒状药物给药的递送装置及其清洁方法
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RU2403059C2 (ru) 2006-02-22 2010-11-10 Маннкайнд Корпорейшн Способ улучшения фармацевтических свойств микрочастиц, содержащих дикетопиперазин и активный агент
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KR100638340B1 (ko) * 2006-03-15 2006-10-27 송인호 낙곡 회수용 흡입기
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CN102036706B (zh) * 2008-05-23 2013-02-27 大塚制药株式会社 粉末吸入器
TWI611818B (zh) 2008-06-13 2018-01-21 曼凱公司 用於藥物傳輸之乾粉吸入器及系統
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JP5479465B2 (ja) 2008-06-20 2014-04-23 マンカインド コーポレイション 吸入努力をリアルタイムにプロファイルする対話式機器および方法
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
WO2010105094A1 (en) 2009-03-11 2010-09-16 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US8734845B2 (en) 2009-06-12 2014-05-27 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
KR20130117755A (ko) 2010-06-21 2013-10-28 맨카인드 코포레이션 건조 분말 약물 운반 시스템 및 방법
BR112013025395B1 (pt) 2011-04-01 2022-02-01 Mannkind Corporation Embalagem de bolha e método de fabricação de uma embalagem de bolhas
CN102218182B (zh) * 2011-06-13 2015-02-18 上海秀新臣邦医药科技有限公司 一种干粉给药装置的振动给药装置
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
CA2852536A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
CN108057154B (zh) 2012-07-12 2021-04-16 曼金德公司 干粉药物输送系统和方法
EP2911690A1 (en) 2012-10-26 2015-09-02 MannKind Corporation Inhalable influenza vaccine compositions and methods
CN108578372B (zh) 2013-03-15 2021-07-06 曼金德公司 微晶二酮哌嗪组合物以及方法
JP6491658B2 (ja) 2013-07-18 2019-03-27 マンカインド コーポレイション 熱安定性乾燥粉末医薬組成物及び方法
CN105517607A (zh) 2013-08-05 2016-04-20 曼金德公司 吹入设备和方法
JP6570189B2 (ja) * 2013-10-15 2019-09-04 ミスティック ファーマシューティカルズ, インコーポレイテッド 制御可能な速度の乱流形成ノズル
GB201401154D0 (en) * 2014-01-23 2014-03-12 Team Holdings Uk Ltd Medical apparatus and method
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CN105031782B (zh) * 2015-06-30 2020-06-26 上海臣邦医药科技股份有限公司 一种提高粉雾剂给药装置加药量计量准确性的方法
CN104971412B (zh) * 2015-06-30 2020-06-26 上海臣邦医药科技股份有限公司 一种粉雾剂给药装置的振动储药单元
CN104971415B (zh) * 2015-06-30 2020-06-26 上海臣邦医药科技股份有限公司 一种粉雾剂给药装置的双振动储药单元
CN104971411B (zh) * 2015-06-30 2023-08-29 上海臣邦医药科技股份有限公司 一种粉雾剂给药装置
CN104971413B (zh) * 2015-06-30 2023-04-14 上海臣邦医药科技股份有限公司 一种粉雾剂给药装置的防误操作单元及防误操作方法
CN111437473B (zh) * 2020-04-16 2023-03-24 宁波诺丁汉大学 一种粉雾剂吸入装置
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CN115814216A (zh) * 2022-11-22 2023-03-21 东莞市中科智恒新材料有限公司 一种高性能电子雾化器

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Also Published As

Publication number Publication date
EP0979115A1 (en) 2000-02-16
NO322447B1 (no) 2006-10-09
HK1029291A1 (en) 2001-03-30
JP4057066B2 (ja) 2008-03-05
CA2283199C (en) 2007-05-29
ATE233113T1 (de) 2003-03-15
AU6431198A (en) 1998-10-12
DK0979115T3 (da) 2003-05-19
NO994434D0 (no) 1999-09-13
KR20000076198A (ko) 2000-12-26
ZA982021B (en) 1999-12-10
PL335690A1 (en) 2000-05-08
CN1810312A (zh) 2006-08-02
JP2007229523A (ja) 2007-09-13
ES2191928T3 (es) 2003-09-16
CA2283199A1 (en) 1998-09-24
AR020247A2 (es) 2002-05-02
PT979115E (pt) 2003-07-31
DE69811655D1 (de) 2003-04-03
SE9700937D0 (sv) 1997-03-14
KR100466998B1 (ko) 2005-01-24
US6257232B1 (en) 2001-07-10
WO1998041264A1 (en) 1998-09-24
CN100500238C (zh) 2009-06-17
JP2001517984A (ja) 2001-10-09
NZ337479A (en) 2001-05-25
EP0979115B1 (en) 2003-02-26
NO994434L (no) 1999-11-03
PL188855B1 (pl) 2005-05-31
DE69811655T2 (de) 2003-12-18

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Legal Events

Date Code Title Description
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]
B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time
B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)