SE8302172L - Forfarande for framstellning av nya acetohydroxamsyror - Google Patents

Forfarande for framstellning av nya acetohydroxamsyror

Info

Publication number
SE8302172L
SE8302172L SE8302172A SE8302172A SE8302172L SE 8302172 L SE8302172 L SE 8302172L SE 8302172 A SE8302172 A SE 8302172A SE 8302172 A SE8302172 A SE 8302172A SE 8302172 L SE8302172 L SE 8302172L
Authority
SE
Sweden
Prior art keywords
group
alkyl
cycloalkyl
conh
cone
Prior art date
Application number
SE8302172A
Other languages
English (en)
Other versions
SE8302172D0 (sv
SE458605B (sv
Inventor
L Lafon
Original Assignee
Lafon Labor
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lafon Labor filed Critical Lafon Labor
Publication of SE8302172D0 publication Critical patent/SE8302172D0/sv
Publication of SE8302172L publication Critical patent/SE8302172L/sv
Publication of SE458605B publication Critical patent/SE458605B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/64—Acyl halides
    • C07C57/72—Acyl halides containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
    • C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings
    • C07D279/22—[b, e]-condensed with two six-membered rings with carbon atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/56—Radicals substituted by sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Claims (1)

1. Analogiforfarande for framstallning av terapeutiskt verk derivat med formeln: samma acetohydroxamsyror med den allmanna formeln: 72 UppflAnore L Lafon, (21)Ans nr Rotel ç51 )Klass (74)0mbud 8302172-5 8109 CO7C 103/28 AWAPATENT AB SA Maisons Paris Alfort FR RI - CH2 - CO - Z. RI - CH2 - SHOE (I) i vilken R, betecknar en grupp Z-A-, dar A betecknar -NH-, -NHCO-, r-A -CONE-, -NHCONH-, -N(C6H5)CONH-, -N Y N-; och Z betecknar en fenY1- eller n-naftylgrupp, varvid vardera as dessa tvA grupper kan vara substituerade med en eller flera av foljande grupper: C1-C4-alkoxi, halogen, CF3 eller NH2; eller Z 5r en adamantylgrupp eller en difenylmetylgrupp forutsatt att (1) Z Hr en difenylmetylgrupp nAr A Hr annat an -CONE-, (11) Z Hr en 1,4-diklorfenylgrupp nat. A Sr -NH-, och Z Hr en 4-aminofenylgrupp nar A Hr -CONE-; samt deras metallsalter och syraadditionssalter nar Ni innehAller en basisk rest,kann`—' ecknat ,v, att ett attiksyra- silken R, har den oven angivna betydelsen, och Z. Hr halogen eller en C1-C3-alkoxigrupp, bringas att reagera med hydroxylamin.
SE8302172A 1976-03-23 1983-04-19 Foerfarande foer framstaellning av acetohydroxamsyror SE458605B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB11710/76A GB1574822A (en) 1976-03-23 1976-03-23 Acetohydroxamic acid derivatives and pharmaceutical compositions thereof
GB629877 1977-02-15

Publications (3)

Publication Number Publication Date
SE8302172D0 SE8302172D0 (sv) 1983-04-19
SE8302172L true SE8302172L (sv) 1983-04-19
SE458605B SE458605B (sv) 1989-04-17

Family

ID=26240593

Family Applications (4)

Application Number Title Priority Date Filing Date
SE7703263A SE432420B (sv) 1976-03-23 1977-03-22 Forfarande for framstellning av terapeutiskt verksamma hydroxamsyror
SE8302172A SE458605B (sv) 1976-03-23 1983-04-19 Foerfarande foer framstaellning av acetohydroxamsyror
SE8302173A SE456992B (sv) 1976-03-23 1983-04-19 Foerfarande foer framstaellning av 2-(1-fenyl-bensimidazolyl)-acetohydroxamsyra
SE8302171A SE452155B (sv) 1976-03-23 1983-04-19 Analogiforfarande for framstellning av terapeutiskt verksamma arylsulfinylacetohydroxamsyraderivat

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7703263A SE432420B (sv) 1976-03-23 1977-03-22 Forfarande for framstellning av terapeutiskt verksamma hydroxamsyror

Family Applications After (2)

Application Number Title Priority Date Filing Date
SE8302173A SE456992B (sv) 1976-03-23 1983-04-19 Foerfarande foer framstaellning av 2-(1-fenyl-bensimidazolyl)-acetohydroxamsyra
SE8302171A SE452155B (sv) 1976-03-23 1983-04-19 Analogiforfarande for framstellning av terapeutiskt verksamma arylsulfinylacetohydroxamsyraderivat

Country Status (25)

Country Link
US (7) US4122186A (sv)
JP (1) JPS52144601A (sv)
AT (5) AT356078B (sv)
AU (1) AU516473B2 (sv)
BE (1) BE852738A (sv)
CA (2) CA1120928A (sv)
CH (1) CH620894A5 (sv)
CS (1) CS200511B2 (sv)
DD (1) DD129645A5 (sv)
DE (1) DE2711451A1 (sv)
DK (1) DK171197B1 (sv)
ES (1) ES457105A1 (sv)
FI (1) FI62821C (sv)
FR (4) FR2345430A1 (sv)
GB (1) GB1574822A (sv)
IE (1) IE44721B1 (sv)
IL (1) IL51705A (sv)
LU (1) LU76989A1 (sv)
NL (1) NL188801C (sv)
NO (4) NO144420C (sv)
NZ (1) NZ183616A (sv)
PH (1) PH16271A (sv)
PT (1) PT66300B (sv)
SE (4) SE432420B (sv)
SU (1) SU689617A3 (sv)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1584462A (en) * 1977-03-31 1981-02-11 Lafon Labor N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them
US4405357A (en) 1980-06-02 1983-09-20 Fmc Corporation Herbicidal 3-isoxazolidinones and hydroxamic acids
FR2502617B1 (sv) * 1981-03-25 1984-04-27 Lafon Labor
FR2528041A1 (fr) * 1982-06-04 1983-12-09 Lafon Labor Acides halogenobenzhydrylsulfinylacetohydroxamiques, procede de preparation et utilisation en therapeutique
JPS59222454A (ja) * 1983-05-31 1984-12-14 Ajinomoto Co Inc アミノ酸の製造方法
US4604407A (en) * 1985-04-04 1986-08-05 E. R. Squibb & Sons, Inc. Hydroxamates
FR2584666B1 (fr) * 1985-07-10 1989-06-16 Champion Spark Plug Europ Bras moteur pour balai d'essuie-glace avec capuchon coulissant
FR2585699B1 (fr) * 1985-07-31 1988-03-11 Lafon Labor Derive d'acide acetohydroxamique, procede de preparation et utilisation en therapeutique
US5036157A (en) * 1986-03-11 1991-07-30 Burroughs Wellcome Co. Aryl derivatives
FR2601673B2 (fr) * 1986-07-21 1989-06-02 Lafon Labor Derives de l'acetamide et medicaments qui en contiennent
US4983567A (en) * 1987-03-16 1991-01-08 Biomeasure, Inc. Immunomodulators and methods of making same
ES2011588A6 (es) * 1989-05-29 1990-01-16 Vinas Lab Procedimiento para la preparacion de un nuevo derivado fenilacetico.
JPH0359402U (sv) * 1989-10-13 1991-06-12
CA2028530A1 (en) * 1989-11-21 1991-05-22 Christian Hubschwerlen Substituted pyrimidobenzimidazole derivatives
US5283248A (en) * 1989-11-21 1994-02-01 Hoffmann-La Roche Inc. Amino substituted pyrimido[1,6-2]benzimidazoles
US5378701A (en) * 1991-12-27 1995-01-03 Kyowa Hakko Kogyo Tricyclic compounds
US6060477A (en) * 1995-06-07 2000-05-09 Cell Pathways, Inc. Method of treating a patient having precancerous lesions with phenyl cycloamino pyrimidinone derivatives
US6172057B1 (en) 1997-02-27 2001-01-09 American Cyanamid Company N-Hydroxy-2-(alkyl, aryl, or heteroaryl sulfanyl, sulfinyl or sulfonyl)-3-substituted alkyl, aryl or heteroarylamides as matrix metalloproteinase inhibitors
JP2001513771A (ja) * 1997-02-27 2001-09-04 アメリカン・サイアナミド・カンパニー マトリクス金属プロテイナーゼ阻害薬としてのｎ−ヒドロキシ−２−（アルキル、アリール、またはヘテロアリールスルファニル、スルフィニルまたはスルホニル）−３−置換アルキル、アリールまたはヘテロアリールアミド
US6187924B1 (en) * 1997-11-12 2001-02-13 Darwin Discovery, Ltd. Hydroxamic and carboxylic acid derivatives having MMP and TNF inhibitory activity
US6686502B1 (en) 1999-03-26 2004-02-03 Ucb S.A. Compounds and methods for treatment of asthma, allergy and inflammatory disorders
PE20001566A1 (es) 1999-03-26 2001-02-05 Ucb Sa Piperazinas 1,4-sustituidas, piperidinas 1,4-sustituidas y 4-alquilidenilpiperidinas 1-sustituidas
GB9911071D0 (en) * 1999-05-12 1999-07-14 Darwin Discovery Ltd Hydroxamic and carboxylic acid derivatives
WO2003048114A2 (en) * 2001-12-04 2003-06-12 De Novo Pharmaceuticals Limited Bacterial enzyme inhibitors
DE10320453A1 (de) * 2003-05-08 2004-11-25 Morphochem AG Aktiengesellschaft für kombinatorische Chemie Neue Bioisostere von Actinonin
US7842835B2 (en) * 2003-07-07 2010-11-30 Georgetown University Histone deacetylase inhibitors and methods of use thereof
EP1644323B1 (en) * 2003-07-07 2015-03-18 Georgetown University Histone deacetylase inhibitors and methods of use thereof
US7417040B2 (en) * 2004-03-01 2008-08-26 Bristol-Myers Squibb Company Fused tricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3
US7378426B2 (en) * 2004-03-01 2008-05-27 Bristol-Myers Squibb Company Fused heterotricyclic compounds as inhibitors of 17β-hydroxysteroid dehydrogenase 3
US20090264384A1 (en) * 2004-11-01 2009-10-22 Nuada, Inc. Indole, benzimidazole, and benzolactam boronic acid compounds, analogs thereof and methods of use thereof
WO2007134169A2 (en) * 2006-05-10 2007-11-22 Nuada, Llc Indole, benzimidazole, and benzolactam boronic acid compounds, analogs thereof and methods of use thereof
WO2007113644A2 (en) * 2006-04-05 2007-10-11 Orchid Research Laboratories Limited New hdac inhibitors
EP2565183A1 (en) 2006-06-28 2013-03-06 Amgen Inc. Glycine transporter-1 inhibitors
AU2007300532A1 (en) * 2006-09-28 2008-04-03 Merck Sharp & Dohme Corp. Pharmaceutical compositions of HDAC inhibitors and chelatable metal compounds, and metal-HDAC inhibitor chelate complexes
CL2007003108A1 (es) * 2006-10-28 2008-07-18 Methylgene Inc Envivo Pharmace Compuestos derivados de n-hidroxiamida sustituida con heterociclos, inhibidores de histona desacetilasa; composicion farmaceutica que comprende a dichos compuestos; y uso para tratar una enfermedad del grupo que consiste en enfermedad de huntington,
US8242174B2 (en) 2007-02-01 2012-08-14 Panthera Biopharma Llc Hydroxamic acid derivatives of aniline useful as therapeutic agents for treating anthrax poisoning
FR2957492B1 (fr) * 2010-03-18 2013-08-16 Rhodia Operations Nouvelles utilisations de composes de type esteramide
CN101982459A (zh) * 2010-10-21 2011-03-02 山东华尔康生物技术有限公司 乙酰氧肟酸的制备工艺
GB201509663D0 (en) * 2015-06-03 2015-07-15 Johnson Matthey Plc Benzo(h)quinoline ligands and complexes thereof
US11970462B1 (en) 2024-01-03 2024-04-30 King Faisal University Ethyl 3-[4,4-bis(4-chlorophenyl)-2,5-dioxoimidazolidin-1-yl]propanoate as an antimicrobial compound

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2862020A (en) * 1958-11-25 Derivatives of a-amino-p-hydroxy
US2279560A (en) * 1940-05-08 1942-04-14 Du Pont Viscous hydrocarbon oil
US2397508A (en) * 1943-05-29 1946-04-02 Standard Oil Co Hydroxamic acids
GB894119A (en) * 1959-11-02 1962-04-18 Ici Ltd Pivalic acid derivative
US3275643A (en) * 1963-07-19 1966-09-27 Irwin I Lubowe Allantoin-pantothenate compounds
US3634509A (en) * 1966-06-08 1972-01-11 Shell Oil Co 2 6-dinitroanilinoacetamides
NL6715600A (sv) * 1966-12-02 1968-06-04
US3927092A (en) * 1968-06-24 1975-12-16 Merck & Co Inc Amides of 2-{8 halophenoxy (or halophenylthio){9 -alkanoic acids
DE1805548A1 (de) * 1968-10-26 1970-10-08 Agfa Gevaert Ag Benzimidazol-Derivate und ihre photographische Verwendung
FR2036953A1 (en) * 1969-04-23 1970-12-31 Pluripharm Diphenylhydantoin derivs
US4092430A (en) * 1970-09-09 1978-05-30 Ciba-Geigy Corporation Antiphlogistic phenylacetohydroxamic acid compositions
US3728380A (en) * 1971-05-17 1973-04-17 Morton Norwich Products Inc P-chlorobenzamidoacetohydroxamic acid
US3839580A (en) * 1972-08-14 1974-10-01 Morton Norwich Products Inc 2-p-(nitrobenzamido)acetohydroxamic for treating urinary tract infections
SE7411007L (sv) * 1973-10-10 1975-04-11 Ciba Geigy Ag
JPS51102636A (en) * 1974-04-03 1976-09-10 Fuji Photo Film Co Ltd Karaashashingazo no keiseihoho
FR2285859A1 (fr) * 1974-09-30 1976-04-23 Lafon Labor Phenylsulfinyl-amidines et derives
CH593954A5 (sv) * 1975-07-21 1977-12-30 Ciba Geigy Ag
US4029812A (en) * 1976-02-18 1977-06-14 The Dow Chemical Company Novel hypolipidemic 2-(3,5-di-tert-butyl-4-hydroxyphenyl)thio carboxamides

Also Published As

Publication number Publication date
IE44721B1 (en) 1982-03-10
IL51705A0 (en) 1977-05-31
ES457105A1 (es) 1978-10-16
SE8302172D0 (sv) 1983-04-19
CA1130301A (en) 1982-08-24
FI770859A (sv) 1977-09-24
NO771006L (no) 1977-09-26
US4209524A (en) 1980-06-24
US4209523A (en) 1980-06-24
US4225617A (en) 1980-09-30
JPS628424B2 (sv) 1987-02-23
SE432420B (sv) 1984-04-02
ATA501480A (de) 1983-08-15
CA1120928A (en) 1982-03-30
AT361932B (de) 1981-04-10
LU76989A1 (sv) 1977-07-18
FR2345430A1 (fr) 1977-10-21
BE852738A (fr) 1977-09-22
AU516473B2 (en) 1981-06-04
FI62821B (fi) 1982-11-30
SE458605B (sv) 1989-04-17
PT66300A (fr) 1977-04-01
DE2711451A1 (de) 1977-10-06
FR2345430B1 (sv) 1982-07-23
DK126677A (da) 1977-09-24
NO152972B (no) 1985-09-16
CH620894A5 (sv) 1980-12-31
ATA839878A (de) 1980-09-15
FR2453148B1 (sv) 1983-12-02
NL188801C (nl) 1992-10-01
ATA840078A (de) 1980-11-15
FR2453133B1 (sv) 1984-04-06
NO803338L (no) 1977-09-26
FR2453133A1 (fr) 1980-10-31
SE8302173D0 (sv) 1983-04-19
SE8302173L (sv) 1983-04-19
DK171197B1 (da) 1996-07-22
PH16271A (en) 1983-08-25
FR2453148A1 (fr) 1980-10-31
FR2453158B1 (sv) 1982-08-06
FI62821C (fi) 1983-03-10
US4183951A (en) 1980-01-15
DD129645A5 (de) 1978-02-01
NO803337L (no) 1977-09-26
NO803336L (no) 1977-09-26
ATA839978A (de) 1980-02-15
PT66300B (pt) 1978-08-10
IE44721L (en) 1977-09-23
AU2334477A (en) 1978-09-21
NZ183616A (en) 1979-03-28
IL51705A (en) 1982-09-30
ATA193077A (de) 1979-09-15
NO146431B (no) 1982-06-21
AT374191B (de) 1984-03-26
NO145881B (no) 1982-03-08
SE7703263L (sv) 1977-09-24
FR2453158A1 (fr) 1980-10-31
DE2711451C2 (sv) 1990-05-10
AT362793B (de) 1981-06-10
AT358556B (de) 1980-09-25
SU689617A3 (ru) 1979-09-30
SE456992B (sv) 1988-11-21
CS200511B2 (en) 1980-09-15
JPS52144601A (en) 1977-12-02
US4152458A (en) 1979-05-01
NO144420B (no) 1981-05-18
NO152972C (no) 1985-12-27
GB1574822A (en) 1980-09-10
SE8302171D0 (sv) 1983-04-19
AT356078B (de) 1980-04-10
US4122186A (en) 1978-10-24
NO145881C (no) 1982-06-16
NO146431C (no) 1982-09-29
NO144420C (no) 1981-08-26
NL7703168A (nl) 1977-09-27
SE8302171L (sv) 1983-04-19
SE452155B (sv) 1987-11-16
US4151300A (en) 1979-04-24

Similar Documents

Publication Publication Date Title
SE8302172L (sv) Forfarande for framstellning av nya acetohydroxamsyror
DE69030206T2 (de) Pyrazolopyridinverbindungen und Verfahren zu ihrer Herstellung
CH344731A (de) Verfahren zur Herstellung von neuen, am Indolstickstoff alkylierten Derivaten der Lysergsäure-Reihe
FI102965B (sv) Förfarande för framställning av nya kondenserade heterocykliska föreni ngar
ATE89559T1 (de) Camptothecin-derivate und verfahren zu ihrer herstellung.
SE7601755L (sv) Anvendning av perfluoralkansulfonamider och/eller ammoniumsalter av perfluoralkansulfonsyror och/eller cyklimmoniumsalter av perfluoralkansulfonsyror som formsleppmedel for termoplastiska, hogmolekyllera, m m
ATE57699T1 (de) Pyridoncarbonsauere-derivate und verfahren zu ihrer herstellung.
HUP0004664A2 (hu) Eljárás acilezett gyűrűs 1,3-dikarbonil-vegyületek előállítására
SE8201738L (sv) Imidiserade polymerer
DE69501705D1 (de) Verfahren zur Herstellung von optisch aktiven Piperazinderivaten und Zwischenprodukten für ihre Herstellung
ATE20588T1 (de) Heterozyklische verbindungen geeignet als pestizide und verfahren zu ihrer herstellung.
US3035093A (en) Substituted alkynyl ureas
US2345385A (en) Pyrazolone salts of sulphonamides
GB103541A (en) Improvement in the Manufacture of alpha alpha Dimethyl-gamma-hydroxy-piperidines substituted in the alpha1 position, including their N-methyl Derivatives.
CH408421A (de) Verfahren zur Herstellung von hochmolekularen Formaldehydpolymeren
FR2338041A1 (fr) Nouveaux acides furobenzoxazolyl-acethydroxamiques, leur procede de preparation et leur application en therapeutique
FI823591L (fi) Nya n-nitroso-n-( -kloroetyl)-karbamoylpeptider
ATE5143T1 (de) Clavulansaeure-derivate und verfahren zu ihrer herstellung.
TH8698EX (th) เททราไฮโดรอิมิดาโซ(1,4)เบนโซไดอะเซพิน-2-ไธโอน ซึ่งต่อต้านเชื้อไวรัส
JPS57142740A (en) Binder for ceramic sheath of precision mold
GB1274765A (en) New dioxazine dyestuffs and processes for their manufacture and use
ES342389A1 (es) Procedimiento para la produccion de nuevas 1 - (2-aminofe- nil)-1,2,3,4-tetrahidroisoquinoleinas.
GB1043999A (en) Anthraquinone dyes of the 2-arylaminoquinizarine series and a process for their production
CH343410A (de) Verfahren zur Herstellung von Cumarinderivaten
GB975859A (en) Process for the production of diorganoboric acid amides

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8302172-5

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8302172-5

Format of ref document f/p: F