SE464194B - Indanderivat, foerfarande foer framstaellning daerav samt farmaceutiska kompositioner - Google Patents

Indanderivat, foerfarande foer framstaellning daerav samt farmaceutiska kompositioner

Info

Publication number
SE464194B
SE464194B SE8401167A SE8401167A SE464194B SE 464194 B SE464194 B SE 464194B SE 8401167 A SE8401167 A SE 8401167A SE 8401167 A SE8401167 A SE 8401167A SE 464194 B SE464194 B SE 464194B
Authority
SE
Sweden
Prior art keywords
group
lower alkyl
substituents
alkyl group
carbon atoms
Prior art date
Application number
SE8401167A
Other languages
English (en)
Swedish (sv)
Other versions
SE8401167D0 (sv
SE8401167L (sv
Inventor
Y Oshiro
H Ueda
K Nakagawa
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3642983A external-priority patent/JPS59161339A/ja
Priority claimed from JP19026983A external-priority patent/JPS6081126A/ja
Priority claimed from JP24587583A external-priority patent/JPS60142919A/ja
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of SE8401167D0 publication Critical patent/SE8401167D0/xx
Publication of SE8401167L publication Critical patent/SE8401167L/xx
Publication of SE464194B publication Critical patent/SE464194B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/34—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C251/42—Oximes with oxygen atoms of oxyimino groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with the carbon atom of at least one of the oxyimino groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
    • C07D295/26—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/747—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
    • C07C49/755—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups a keto group being part of a condensed ring system with two or three rings, at least one ring being a six-membered aromatic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE8401167A 1983-03-04 1984-03-02 Indanderivat, foerfarande foer framstaellning daerav samt farmaceutiska kompositioner SE464194B (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP3642983A JPS59161339A (ja) 1983-03-04 1983-03-04 インダン誘導体
JP19026983A JPS6081126A (ja) 1983-10-11 1983-10-11 低酸素症改善剤
JP24587583A JPS60142919A (ja) 1983-12-29 1983-12-29 抗酸化剤

Publications (3)

Publication Number Publication Date
SE8401167D0 SE8401167D0 (sv) 1984-03-02
SE8401167L SE8401167L (sv) 1984-09-05
SE464194B true SE464194B (sv) 1991-03-18

Family

ID=27289096

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8401167A SE464194B (sv) 1983-03-04 1984-03-02 Indanderivat, foerfarande foer framstaellning daerav samt farmaceutiska kompositioner

Country Status (11)

Country Link
US (1) US4792628A (fr)
KR (1) KR910003337B1 (fr)
CA (1) CA1245663A (fr)
CH (1) CH664359A5 (fr)
DE (1) DE3407842A1 (fr)
ES (2) ES8602606A1 (fr)
FR (1) FR2569183B1 (fr)
GB (1) GB2135999B (fr)
IT (1) IT1178868B (fr)
NL (1) NL8400711A (fr)
SE (1) SE464194B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6169747A (ja) * 1984-08-31 1986-04-10 Otsuka Pharmaceut Co Ltd ２，３―ジヒドロ―１ｈ―インデン誘導体及びその製造法
DK575387A (da) * 1986-11-04 1988-05-05 Otsuka Pharma Co Ltd Hydrofluorenderivater, fremgangsmaade til fremstilling deraf og praeparater indeholdende saadanne forbindelser
CA2109515A1 (fr) * 1991-05-29 1992-11-30 Robert L. Dow Inhibiteurs de la dihydroxyindanone-tyrosine-kinase
US5877218A (en) 1994-01-10 1999-03-02 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using 1-aminoindan and derivatives thereof and process for preparing optically active 1-aminoindan derivatives
US5646188A (en) * 1995-07-05 1997-07-08 Teva Pharmaceutical Industries, Ltd. Polyamine derivatives of 1-aminoindan
WO1997025436A1 (fr) * 1996-01-12 1997-07-17 Nippon Steel Chemical Co., Ltd. Procede de production de derives de l'indane
IL130528A (en) 1996-12-18 2004-12-15 Teva Pharma Aminoindan derivatives, pharmaceutical compositions comprising them and uses thereof
DE19749453A1 (de) * 1997-11-10 1999-05-12 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte anellierte 5-Ring-Verbindungen, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
US6737547B1 (en) 1998-12-31 2004-05-18 Teva Pharmaceutical Industries, Ltd. Compositions containing and methods of using N-acyl-1H-aminoindenes
EP1242066B1 (fr) 1999-10-27 2006-06-28 Teva Pharmaceutical Industries Ltd. Utilisation de derives de 1-aminoindan pour le traitement de la manie liee a la psychose maniacod pressive
US20040010038A1 (en) * 2002-02-27 2004-01-15 Eran Blaugrund Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors
BRPI0620659A2 (pt) * 2005-12-09 2017-10-31 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd método para a prevenção do aparecimento de sintomas de uma doença neurodegenerativa em um indivíduo predisposto à doença neurodegenerativa, método de redução de stress oxidante no cérebro de um indivíduo afligido com stress oxidante, método de tratamento de um indivíduo afligido com a degeneração cognitiva suave e composição farmacêutica
TW200744576A (en) * 2006-02-24 2007-12-16 Teva Pharma Propargylated aminoindans, processes for preparation, and uses thereof
IN2014DN10198A (fr) 2012-05-11 2015-08-07 Mitsubishi Gas Chemical Co
CN103086834B (zh) * 2013-01-08 2015-05-27 上海化工研究院 一种联芳基茚类化合物的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2916490A (en) * 1959-12-08 Ocjhs
US3709996A (en) * 1963-08-02 1973-01-09 Aspro Nicholas Ltd Pharmaceutical compositions containing n-cyclopropyl-1-aminoindane compounds and adapted for administration to obtain inhibition of monoamine oxidase enzyme and process
US3637740A (en) * 1969-04-21 1972-01-25 Pfizer Aminobenzocycloalkane compounds
FR2456738A2 (fr) * 1978-04-10 1980-12-12 Delalande Sa Nouvelles cinnamoyles piperazines et homopiperazines, leur procede de preparation et leur application en therapeutique
CA1109080A (fr) * 1978-05-30 1981-09-15 Hideo Kato Derives de l'indanamine

Also Published As

Publication number Publication date
KR840009060A (ko) 1984-12-24
SE8401167D0 (sv) 1984-03-02
SE8401167L (sv) 1984-09-05
NL8400711A (nl) 1984-10-01
GB2135999A (en) 1984-09-12
CA1245663A (fr) 1988-11-29
DE3407842A1 (de) 1984-09-06
IT8467205A0 (it) 1984-03-02
ES8604141A1 (es) 1986-01-16
ES530269A0 (es) 1985-12-01
FR2569183A1 (fr) 1986-02-21
KR910003337B1 (ko) 1991-05-27
FR2569183B1 (fr) 1988-06-24
ES8602606A1 (es) 1985-12-01
IT1178868B (it) 1987-09-16
CH664359A5 (de) 1988-02-29
GB2135999B (en) 1987-05-20
GB8405711D0 (en) 1984-04-11
US4792628A (en) 1988-12-20
ES544290A0 (es) 1986-01-16
IT8467205A1 (it) 1985-09-02

Similar Documents

Publication Publication Date Title
SE464194B (sv) Indanderivat, foerfarande foer framstaellning daerav samt farmaceutiska kompositioner
JPH07503718A (ja) 新規なアミジン誘導体，その製法，及びｌｔｂ↓４拮抗剤としての使用
JPH03106858A (ja) ベンゾイルグアニジン、その製法およびそれを含有する医薬
JPH03109378A (ja) 新規なベンゾイミダゾール化合物
JPS60142932A (ja) 血小板活性化因子に対するきつ抗体として有用なインデン誘導体
JPH0597765A (ja) ナフトキノン化合物
US9464051B2 (en) Compositions and methods for the treatment of inflammation and pain
FI78677B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara naftokinoner, och vid foerfarandet anvaendbara mellanprodukter.
WO1998022442A2 (fr) Compositions pharmaceutiques contenant des composes de diaryl-cyclomethylenepyrazole et leur utilisation en tant qu'inhibiteurs de la cyclooxygenase i (cox i)
JP2020520949A (ja) 組成物、並びにミトコンドリア脱共役剤を調製及び使用する方法
JPH0477740B2 (fr)
JPS6156168A (ja) 新規化合物およびそれらの製造方法
KR900001194B1 (ko) N-아미노피리디늄 베타인 유도체의 제조방법
US5140047A (en) Lipoxygenase inhibitors
US9403857B2 (en) Compositions and methods for the treatment of metabolic syndrome
US7902249B2 (en) Indole derivatives substituted with long-chain alcohols and medicaments containing them
US11274106B2 (en) Topoisomerase inhibitors with antibacterial and anticancer activity
CN112679409A (zh) 一种4-吲哚-取代硫半脲衍生物及其制备方法和应用
JPS6160610A (ja) 低酸素症改善剤
JPH058181B2 (fr)
WO2013167991A1 (fr) Compositions et méthodes de traitement de troubles métaboliques
JPH0447646B2 (fr)
WO2013167997A2 (fr) Compositions et méthodes de traitement du syndrome métabolique
JPH03128340A (ja) インダン誘導体
JPS58113128A (ja) 脂質調節機能を有し且つｎ置換ベンゼンスルホンアミド型構造の化合物を含有する医薬組成物

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8401167-5

Effective date: 19931008

Format of ref document f/p: F