FR2456738A2 - Nouvelles cinnamoyles piperazines et homopiperazines, leur procede de preparation et leur application en therapeutique - Google Patents
Nouvelles cinnamoyles piperazines et homopiperazines, leur procede de preparation et leur application en therapeutiqueInfo
- Publication number
- FR2456738A2 FR2456738A2 FR7833468A FR7833468A FR2456738A2 FR 2456738 A2 FR2456738 A2 FR 2456738A2 FR 7833468 A FR7833468 A FR 7833468A FR 7833468 A FR7833468 A FR 7833468A FR 2456738 A2 FR2456738 A2 FR 2456738A2
- Authority
- FR
- France
- Prior art keywords
- cinnamoyles
- piperazines
- homopiperazines
- therapeutics
- novel
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
- C07D321/02—Seven-membered rings
- C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/54—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/66—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
A.NOUVELLES CINNAMOYLES PIPERAZINES ET HOMOPIPERAZINES. B.CES NOUVELLES CINNAMOYLES PIPERAZINES REPONDENT A LA FORMULE: (CF DESSIN DANS BOPI) OU (N, R, X, M) (2, OH, OX, O) AR PHENYLE OU BENZODIOXANE SUBSTITUE; (1, H, OX, O) ET AR BENZODIOXANE SUBSTITUE; (1, OH, S, O) ET AR PHENYLE OU BENZODIOXANE SUBSTITUE; (1, OH, -N-O) ET AR PHENYLE; (CF DESSIN DANS BOPI) C.UTILISABLES COMME MEDICAMENTS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/894,965 US4178442A (en) | 1977-04-19 | 1978-04-10 | Novel cinnamoyles piperazines and homopiperazines, the method of preparing them and their application in therapeutics |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2456738A2 true FR2456738A2 (fr) | 1980-12-12 |
FR2456738B2 FR2456738B2 (fr) | 1983-01-14 |
Family
ID=25403749
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7833468A Granted FR2456738A2 (fr) | 1978-04-10 | 1978-11-27 | Nouvelles cinnamoyles piperazines et homopiperazines, leur procede de preparation et leur application en therapeutique |
FR7917586A Granted FR2438044A2 (fr) | 1978-04-10 | 1979-07-06 | Nouveaux derives de l'alkylene dioxy-1, 2 benzene |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7917586A Granted FR2438044A2 (fr) | 1978-04-10 | 1979-07-06 | Nouveaux derives de l'alkylene dioxy-1, 2 benzene |
Country Status (3)
Country | Link |
---|---|
FR (2) | FR2456738A2 (fr) |
LU (1) | LU80680A1 (fr) |
SE (2) | SE438149B (fr) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2497512A2 (fr) * | 1981-01-07 | 1982-07-09 | Delalande Sa | Nouveaux derives de la trimethoxy-3,4,5 cinnamoyl piperazine, leurs sels, leur procede de preparation et leur application en therapeutique |
FR2507604A2 (fr) * | 1977-04-19 | 1982-12-17 | Delalande Sa | Nouvelles trimethoxy-3,4,5 cinnamoyle piperazines, leur procede de preparation et leur application en therapeutique |
US4499100A (en) * | 1983-05-18 | 1985-02-12 | Syntex (U.S.A.) Inc. | Benzodioxanyl-hydroxyethyleneamino-piperidinyl acetanilides, ketones, esters and carbamates which effect immunity and calcium entry and β-blockade |
US4558129A (en) * | 1983-05-18 | 1985-12-10 | Syntex (U.S.A.) Inc. | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade |
US4567264A (en) * | 1983-05-18 | 1986-01-28 | Syntex (U.S.A.) Inc. | Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry |
FR2569183A1 (fr) * | 1983-03-04 | 1986-02-21 | Otsuka Pharma Co Ltd | Derives d'indane et leurs sels, leur procede de preparation et leur application en therapeutique |
GB2190084A (en) * | 1984-03-02 | 1987-11-11 | Roehm Pharma Gmbh | Benzyl cyanides |
EP0338906A2 (fr) * | 1988-04-16 | 1989-10-25 | Daicel Chemical Industries, Ltd. | Procédé de moulage d'un substrat formaté pour disque optique et moule pour la mise en oeuvre du procédé |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6514996B2 (en) | 1995-05-19 | 2003-02-04 | Kyowa Hakko Kogyo Co., Ltd. | Derivatives of benzofuran or benzodioxole |
CA2272327A1 (fr) * | 1996-11-19 | 1998-05-28 | Kyowa Hakko Kogyo Co., Ltd. | Composes heterocycliques d'oxygene |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2267104A1 (en) * | 1974-04-12 | 1975-11-07 | Ferlux Labo Sa | Hypotensive and antiarrhythmic piperazines - 1-(3-phenoxy-2-hydroxy propyl)-4-substd. piperazines |
LU72664A1 (fr) * | 1974-06-05 | 1976-11-11 | ||
BE865990A (fr) * | 1977-04-19 | 1978-10-16 | Delalande Sa | Nouvelles cinnamoyles piperazines et homopiperazines, leur procede de preparation et leur application en therapeutique |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2396757A2 (fr) * | 1977-07-08 | 1979-02-02 | Ile De France | Nouveaux 2,3-alkylene bis (oxy) benzamides substitues, leurs derives et leurs procedes de preparation |
-
1978
- 1978-11-27 FR FR7833468A patent/FR2456738A2/fr active Granted
- 1978-12-20 LU LU80680A patent/LU80680A1/fr unknown
-
1979
- 1979-01-02 SE SE7900020A patent/SE438149B/sv not_active IP Right Cessation
- 1979-07-06 FR FR7917586A patent/FR2438044A2/fr active Granted
- 1979-09-03 SE SE7907312A patent/SE431752B/sv not_active IP Right Cessation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2267104A1 (en) * | 1974-04-12 | 1975-11-07 | Ferlux Labo Sa | Hypotensive and antiarrhythmic piperazines - 1-(3-phenoxy-2-hydroxy propyl)-4-substd. piperazines |
LU72664A1 (fr) * | 1974-06-05 | 1976-11-11 | ||
BE865990A (fr) * | 1977-04-19 | 1978-10-16 | Delalande Sa | Nouvelles cinnamoyles piperazines et homopiperazines, leur procede de preparation et leur application en therapeutique |
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2507604A2 (fr) * | 1977-04-19 | 1982-12-17 | Delalande Sa | Nouvelles trimethoxy-3,4,5 cinnamoyle piperazines, leur procede de preparation et leur application en therapeutique |
FR2497512A2 (fr) * | 1981-01-07 | 1982-07-09 | Delalande Sa | Nouveaux derives de la trimethoxy-3,4,5 cinnamoyl piperazine, leurs sels, leur procede de preparation et leur application en therapeutique |
FR2569183A1 (fr) * | 1983-03-04 | 1986-02-21 | Otsuka Pharma Co Ltd | Derives d'indane et leurs sels, leur procede de preparation et leur application en therapeutique |
US4499100A (en) * | 1983-05-18 | 1985-02-12 | Syntex (U.S.A.) Inc. | Benzodioxanyl-hydroxyethyleneamino-piperidinyl acetanilides, ketones, esters and carbamates which effect immunity and calcium entry and β-blockade |
US4558129A (en) * | 1983-05-18 | 1985-12-10 | Syntex (U.S.A.) Inc. | Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade |
US4567264A (en) * | 1983-05-18 | 1986-01-28 | Syntex (U.S.A.) Inc. | Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry |
GB2190084A (en) * | 1984-03-02 | 1987-11-11 | Roehm Pharma Gmbh | Benzyl cyanides |
EP0338906A2 (fr) * | 1988-04-16 | 1989-10-25 | Daicel Chemical Industries, Ltd. | Procédé de moulage d'un substrat formaté pour disque optique et moule pour la mise en oeuvre du procédé |
EP0338906A3 (fr) * | 1988-04-16 | 1992-01-15 | Daicel Chemical Industries, Ltd. | Procédé de moulage d'un substrat formaté pour disque optique et moule pour la mise en oeuvre du procédé |
Also Published As
Publication number | Publication date |
---|---|
FR2438044B2 (fr) | 1982-04-09 |
SE438149B (sv) | 1985-04-01 |
SE7900020L (sv) | 1979-10-11 |
LU80680A1 (fr) | 1980-07-21 |
FR2456738B2 (fr) | 1983-01-14 |
SE7907312L (sv) | 1979-10-11 |
SE431752B (sv) | 1984-02-27 |
FR2438044A2 (fr) | 1980-04-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
TP | Transmission of property |