FR2438044A2 - Nouveaux derives de l'alkylene dioxy-1, 2 benzene - Google Patents

Nouveaux derives de l'alkylene dioxy-1, 2 benzene

Info

Publication number
FR2438044A2
FR2438044A2 FR7917586A FR7917586A FR2438044A2 FR 2438044 A2 FR2438044 A2 FR 2438044A2 FR 7917586 A FR7917586 A FR 7917586A FR 7917586 A FR7917586 A FR 7917586A FR 2438044 A2 FR2438044 A2 FR 2438044A2
Authority
FR
France
Prior art keywords
carboxamido
carbamoylamino
oxygen
methyl
intermediates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7917586A
Other languages
English (en)
Other versions
FR2438044B2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/894,965 external-priority patent/US4178442A/en
Application filed by Delalande SA filed Critical Delalande SA
Publication of FR2438044A2 publication Critical patent/FR2438044A2/fr
Application granted granted Critical
Publication of FR2438044B2 publication Critical patent/FR2438044B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02—Seven-membered rings
    • C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/54—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/66—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

A.NOUVEAUX DERIVES DE L'ALKYLENE DIOXY-1,2 BENZENE. B.ILS REPONDENT A LA FORMULE: (CF DESSIN DANS BOPI) DANS LAQUELLE: -R REPRESENTE LE GROUPEMENT -CH OU L'ATOME D'HYDROGENE, AUQUEL LES PARAMETRES X, N REPRESENTENT OX, 2, OX, 1, OX, 3, S, 2, OU -R REPRESENTE LE GROUPEMENT -CH-
FR7917586A 1978-04-10 1979-07-06 Nouveaux derives de l'alkylene dioxy-1, 2 benzene Granted FR2438044A2 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/894,965 US4178442A (en) 1977-04-19 1978-04-10 Novel cinnamoyles piperazines and homopiperazines, the method of preparing them and their application in therapeutics

Publications (2)

Publication Number Publication Date
FR2438044A2 true FR2438044A2 (fr) 1980-04-30
FR2438044B2 FR2438044B2 (fr) 1982-04-09

Family

ID=25403749

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7833468A Granted FR2456738A2 (fr) 1978-04-10 1978-11-27 Nouvelles cinnamoyles piperazines et homopiperazines, leur procede de preparation et leur application en therapeutique
FR7917586A Granted FR2438044A2 (fr) 1978-04-10 1979-07-06 Nouveaux derives de l'alkylene dioxy-1, 2 benzene

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR7833468A Granted FR2456738A2 (fr) 1978-04-10 1978-11-27 Nouvelles cinnamoyles piperazines et homopiperazines, leur procede de preparation et leur application en therapeutique

Country Status (3)

Country Link
FR (2) FR2456738A2 (fr)
LU (1) LU80680A1 (fr)
SE (2) SE438149B (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2507604A2 (fr) * 1977-04-19 1982-12-17 Delalande Sa Nouvelles trimethoxy-3,4,5 cinnamoyle piperazines, leur procede de preparation et leur application en therapeutique
EP0943613A1 (fr) * 1996-11-19 1999-09-22 Kyowa Hakko Kogyo Kabushiki Kaisha Composes heterocycliques d'oxygene
US6514996B2 (en) 1995-05-19 2003-02-04 Kyowa Hakko Kogyo Co., Ltd. Derivatives of benzofuran or benzodioxole

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2497512A2 (fr) * 1981-01-07 1982-07-09 Delalande Sa Nouveaux derives de la trimethoxy-3,4,5 cinnamoyl piperazine, leurs sels, leur procede de preparation et leur application en therapeutique
DE3407842A1 (de) * 1983-03-04 1984-09-06 Otsuka Pharmaceutical Co. Ltd., Tokyo Indanderivate und deren salze, verfahren zu deren herstellung und arzneimittel und antioxidationsmittel, welche diese enthalten
US4558129A (en) * 1983-05-18 1985-12-10 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethylene-piperazinyl acetanilides which effect calcium entry and β-blockade
US4499100A (en) * 1983-05-18 1985-02-12 Syntex (U.S.A.) Inc. Benzodioxanyl-hydroxyethyleneamino-piperidinyl acetanilides, ketones, esters and carbamates which effect immunity and calcium entry and β-blockade
US4567264A (en) * 1983-05-18 1986-01-28 Syntex (U.S.A.) Inc. Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry
DE3407695A1 (de) * 1984-03-02 1985-09-12 Röhm Pharma GmbH, 6108 Weiterstadt Pteridinverbindungen mit pharmazeutischer wirksamkeit
US5106553A (en) * 1988-04-16 1992-04-21 Daicel Chemical Industries, Ltd. Method for molding a formatted substrate for an optical disk

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2396757A2 (fr) * 1977-07-08 1979-02-02 Ile De France Nouveaux 2,3-alkylene bis (oxy) benzamides substitues, leurs derives et leurs procedes de preparation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2267104A1 (en) * 1974-04-12 1975-11-07 Ferlux Labo Sa Hypotensive and antiarrhythmic piperazines - 1-(3-phenoxy-2-hydroxy propyl)-4-substd. piperazines
GB1521471A (en) * 1974-06-05 1978-08-16 Randall & Son Ltd J Token-deposit locks
FR2387971A1 (fr) * 1977-04-19 1978-11-17 Delalande Sa Nouvelles trimethoxy cinnamoyles piperazines, leur procede de preparation et leur application en therapeutique

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2396757A2 (fr) * 1977-07-08 1979-02-02 Ile De France Nouveaux 2,3-alkylene bis (oxy) benzamides substitues, leurs derives et leurs procedes de preparation

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2507604A2 (fr) * 1977-04-19 1982-12-17 Delalande Sa Nouvelles trimethoxy-3,4,5 cinnamoyle piperazines, leur procede de preparation et leur application en therapeutique
US6514996B2 (en) 1995-05-19 2003-02-04 Kyowa Hakko Kogyo Co., Ltd. Derivatives of benzofuran or benzodioxole
US6716987B1 (en) 1995-05-19 2004-04-06 Kyowa Hakko Kogyo Co., Ltd. Derivatives of benzofuran or benzodioxazole compounds
EP0943613A1 (fr) * 1996-11-19 1999-09-22 Kyowa Hakko Kogyo Kabushiki Kaisha Composes heterocycliques d'oxygene
EP0943613A4 (fr) * 1996-11-19 2002-07-10 Kyowa Hakko Kogyo Kk Composes heterocycliques d'oxygene

Also Published As

Publication number Publication date
FR2456738A2 (fr) 1980-12-12
SE431752B (sv) 1984-02-27
LU80680A1 (fr) 1980-07-21
SE7900020L (sv) 1979-10-11
FR2456738B2 (fr) 1983-01-14
FR2438044B2 (fr) 1982-04-09
SE7907312L (sv) 1979-10-11
SE438149B (sv) 1985-04-01

Similar Documents

Publication Publication Date Title
FR2438044A2 (fr) Nouveaux derives de l'alkylene dioxy-1, 2 benzene
NO930193L (no) Biarylsubstituerte 4-aminosmoersyreamider
RS67204A (en) Tripeptides having a hydroxyproline ether of a substituted quinoline for inhibition of ns3 (hepatitis c)
CO4410318A1 (es) Compuestos de naftilo, intermedios, procedimientos, composiciones y metodos
GB1426385A (en) Compounds for diagnostic use with high susceptibility to trypsin and other proteolytic enzymes of the type peptide peptidohydro lases
NO840551L (no) Fremgangsmaate ved fremstilling av terapeutisk virksomme 1,2,3,5-tetrahydroimidazo-(2,1-b)-kinazoliner
AR039226A2 (es) Compuestos utiles como intermediarios de preparacion y procedimientos
FI885518A0 (fi) Menetelmä uusien terapeuttisesti käyttökelpoisten 4,5-dihydro-4-okso-5-isopropyyli-imidatso/1,5-a/kinoksaliinijohdannaisten valmistamiseksi
DE60005390D1 (de) Hcv ns3 proteaseinhibitoren
NO944069L (no) Hemming av uterinfibrose
CA2414960A1 (fr) Amides d'acide carboxylique, azides et amino-alcools et procedes de preparation de .alpha-ceto amides a l'aide de ces derniers
DK300890A (da) Kondenserede pyrazol-3-oxo-propannitrilderivater og fremgangsmaade til fremstilling deraf
AR023369A1 (es) Secretagogos de la hormona del crecimiento
ES2012736A6 (es) Procedimiento para la preparacion de derivados triciclicos de 3-oxopropanonitrilo.
ES2058247T3 (es) 4-hidroxicinnolin-carboxamidas, su utilizacion y metodo de preparacion.
IE781167L (en) Ó-halomethyl amino acids.
MXPA03000337A (es) Inhibidores de trombina que comprenden un grupo aminoisoquinolina.
AR038916A1 (es) Derivados de azepano con actividad anticancerigena
MY123639A (en) Substituted isoquinoline derivatives and their use as inticonvulsants
CA2456426A1 (fr) Nouveaux derives d'acide mandelique et leur utilisation comme inhibiteurs de la thrombine
CA2430909A1 (fr) Inhibiteurs du papillomavirus
GB1492663A (en) 4-amino-3-pyrrole carboxamides
GB1367743A (en) 2,4,5-trisubstituted oxazoles and pharmaceutical uses thereof
EA200000291A1 (ru) Замещенные 2-фенил-3(2h)-пиридазиноны
GB1450286A (en) Benzoyl phenylguanidines their preparation and their medicinal use

Legal Events

Date Code Title Description
TP Transmission of property