NO944069L - Hemming av uterinfibrose - Google Patents
Hemming av uterinfibroseInfo
- Publication number
- NO944069L NO944069L NO944069A NO944069A NO944069L NO 944069 L NO944069 L NO 944069L NO 944069 A NO944069 A NO 944069A NO 944069 A NO944069 A NO 944069A NO 944069 L NO944069 L NO 944069L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- aryl
- optionally substituted
- substituted
- halo
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Anvendelse av en forbindelse med formelen hvor R er: hydrogen; hydroksy; Cj-C^-alkoksy; en gruppe med forme- len -0-C(0)-Ra. hvor Ra er hydrogen, Cj-C^-alkyl som eventuelt er substituert med aralno, halo, karbonyl , Cj- C^-alkoksykarbonyl , C1-C7-alkanoyloksy , karbamoyl og/eller aryl ; eller Ra er Cj-Cfc-alkenyl som eventuelt er substituert med aryl ; eller Ra er en C3-C7-cykloal- kyl ; eller Ra er aryl som eventuelt er substituert med hydroksy, C^-C^-alkyl , Cj-C^-alkoksy og/eller halo; eller Ra er -0-aryl , hvor nevnte aryl eventuelt er substituert med hydroksy Cj-C^-alkyl , C1-C6-alkoksy , og/eller halo, eller R er en gruppe med formelen -0-S02~Rb hvor Rb kan være Cj-C^-alkyl eller aryl som eventuelt er substitu- ert med C-C eller R er karbamoyloksy hvor nitrogenet kan være substituert en eller to ganger med C^-C^-alkyl ; eller R er en gruppe med formelen -0-C(0)RC-0-(C1-C6- alkyl ) hvor Rc er en binding eller Cj-C^-alkandlyl ; R1 er halo, Cj-C^-alkyl , C1-C7-alkyl substituert med Cj-Cfc-alkyl, substituert eller ikke-substituert 03-07- cykloalkyl, eller substituert eller Ikke-substltuert R2 er O eller CH2: R3 er CH2 eller (CH2)2; O , II R4 er -C-, CH2 eller en binding: og R5 er amino, nltrilo som eventuelt er substituert en eller to ganger med Cj-C^-alkyl; eller en N-heterocyk- llsk ring som eventuelt har et annet heteroatom valgt fra N, O eller S i nevnte ring; eller et farmasøytisk akseptabelt salt eller solvat derav, i fremstillingen av et medikament som er nyttig for hemming av uterln- fibrose.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/145,016 US5480904A (en) | 1993-10-28 | 1993-10-28 | Methods for inhibiting uterine fibrosis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO944069D0 NO944069D0 (no) | 1994-10-26 |
| NO944069L true NO944069L (no) | 1995-05-02 |
Family
ID=22511226
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO944069A NO944069L (no) | 1993-10-28 | 1994-10-26 | Hemming av uterinfibrose |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5480904A (no) |
| EP (1) | EP0650724A1 (no) |
| JP (1) | JPH07188011A (no) |
| KR (1) | KR950010894A (no) |
| CN (1) | CN1109749A (no) |
| AU (1) | AU681701B2 (no) |
| CA (1) | CA2134304A1 (no) |
| CZ (1) | CZ264594A3 (no) |
| HU (1) | HUT72445A (no) |
| IL (1) | IL111430A (no) |
| NO (1) | NO944069L (no) |
| NZ (1) | NZ264764A (no) |
| PH (1) | PH31597A (no) |
| RU (1) | RU94039540A (no) |
| UA (1) | UA27057C2 (no) |
| ZA (1) | ZA948390B (no) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5811447A (en) * | 1993-01-28 | 1998-09-22 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US6515009B1 (en) | 1991-09-27 | 2003-02-04 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US5770609A (en) | 1993-01-28 | 1998-06-23 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
| US6251920B1 (en) | 1993-05-13 | 2001-06-26 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies |
| US6491938B2 (en) | 1993-05-13 | 2002-12-10 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US6197789B1 (en) | 1995-06-07 | 2001-03-06 | Neorx Corporation | Prevention and treatment of cardiovascular pathologies with tamoxifen analogues |
| CA2162586C (en) | 1993-05-13 | 2006-01-03 | David J. Grainger | Prevention and treatment of pathologies associated with abnormally proliferative smooth muscle cells |
| US20030083733A1 (en) * | 1997-10-10 | 2003-05-01 | Neorx Corporation | Therapeutic inhibitor of vascular smooth muscle cells |
| US20020091433A1 (en) * | 1995-04-19 | 2002-07-11 | Ni Ding | Drug release coated stent |
| US6099562A (en) * | 1996-06-13 | 2000-08-08 | Schneider (Usa) Inc. | Drug coating with topcoat |
| US5837313A (en) * | 1995-04-19 | 1998-11-17 | Schneider (Usa) Inc | Drug release stent coating process |
| AU6335496A (en) * | 1995-06-26 | 1997-01-30 | Eli Lilly And Company | Benzothiophene compounds |
| US20040039030A1 (en) | 1996-09-27 | 2004-02-26 | Hoechst Akeengesellschaft | Use of 1-hydroxy-2-pyridones for the treatment of seborrheic dermatitis |
| DE19639816A1 (de) | 1996-09-27 | 1998-04-02 | Hoechst Ag | Antimykotische Mittel mit hoher Wirkstofffreisetzung |
| WO1998046588A2 (en) * | 1997-04-11 | 1998-10-22 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
| US6613083B2 (en) * | 2001-05-02 | 2003-09-02 | Eckhard Alt | Stent device and method |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
| US4418068A (en) * | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
| US4380635A (en) * | 1981-04-03 | 1983-04-19 | Eli Lilly And Company | Synthesis of acylated benzothiophenes |
| US5395842A (en) * | 1988-10-31 | 1995-03-07 | Endorecherche Inc. | Anti-estrogenic compounds and compositions |
| JP3157882B2 (ja) * | 1991-11-15 | 2001-04-16 | 帝国臓器製薬株式会社 | 新規なベンゾチオフエン誘導体 |
| GB9318591D0 (en) * | 1993-09-08 | 1993-10-27 | Ellis Christopher W H | Kinetic energy storage system |
-
1993
- 1993-10-28 US US08/145,016 patent/US5480904A/en not_active Expired - Fee Related
-
1994
- 1994-10-25 ZA ZA948390A patent/ZA948390B/xx unknown
- 1994-10-25 CA CA002134304A patent/CA2134304A1/en not_active Abandoned
- 1994-10-25 NZ NZ264764A patent/NZ264764A/en unknown
- 1994-10-25 JP JP6260283A patent/JPH07188011A/ja not_active Withdrawn
- 1994-10-26 RU RU94039540/14A patent/RU94039540A/ru unknown
- 1994-10-26 NO NO944069A patent/NO944069L/no unknown
- 1994-10-26 CZ CZ942645A patent/CZ264594A3/cs unknown
- 1994-10-26 UA UA94105968A patent/UA27057C2/uk unknown
- 1994-10-26 EP EP94307884A patent/EP0650724A1/en not_active Withdrawn
- 1994-10-26 KR KR1019940027389A patent/KR950010894A/ko not_active Application Discontinuation
- 1994-10-26 PH PH49238A patent/PH31597A/en unknown
- 1994-10-26 AU AU77493/94A patent/AU681701B2/en not_active Ceased
- 1994-10-27 HU HU9403095A patent/HUT72445A/hu unknown
- 1994-10-27 CN CN94117658A patent/CN1109749A/zh active Pending
- 1994-10-27 IL IL11143094A patent/IL111430A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR950010894A (ko) | 1995-05-15 |
| UA27057C2 (uk) | 2000-02-28 |
| AU7749394A (en) | 1995-05-18 |
| NO944069D0 (no) | 1994-10-26 |
| NZ264764A (en) | 1997-06-24 |
| JPH07188011A (ja) | 1995-07-25 |
| HU9403095D0 (en) | 1994-12-28 |
| EP0650724A1 (en) | 1995-05-03 |
| PH31597A (en) | 1998-11-03 |
| IL111430A (en) | 1999-12-31 |
| RU94039540A (ru) | 1996-11-10 |
| AU681701B2 (en) | 1997-09-04 |
| ZA948390B (en) | 1996-04-25 |
| CN1109749A (zh) | 1995-10-11 |
| IL111430A0 (en) | 1994-12-29 |
| HUT72445A (en) | 1996-04-29 |
| CZ264594A3 (en) | 1995-05-17 |
| US5480904A (en) | 1996-01-02 |
| CA2134304A1 (en) | 1995-04-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO944069L (no) | Hemming av uterinfibrose | |
| NO943852L (no) | Fremgangsmåte for å hemme bentap | |
| CA2044748A1 (en) | Pyrazolopyrimidinone antianginal agents | |
| CO5550421A2 (es) | Derivados de indol utiles para el tratamiento de enfermeda- des | |
| TW370529B (en) | Pyrazolopyrimidines | |
| NO943853L (no) | Senking av serumkolesterol | |
| DE60236851D1 (en) | Pyrimidinmatrixmetalloproteinaseinhibitoren | |
| CO5251381A1 (es) | Derivados de adamantano, un proceso para su preparacion y composiciones farmaceuticas que los contienen | |
| HUP0204474A2 (hu) | 1H-imidazopiridin-származékok, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk | |
| DK34793A (da) | Vandoploeseligt, farmaceutisk acceptabelt salt af et monoacylderivat af rapamycin, fremgangsmaade til dets fremstilling og injicerbart, farmaceutisk praeparat indeholdende det | |
| RS50378B (sr) | N-heterociklični derivati kao nos inhibitori | |
| BG108089A (en) | Pyridine matrix metalloproteinase inhibitors | |
| AR047339A1 (es) | Derivados de difenilazetidona.proceso de obtencion. | |
| SE9703377D0 (sv) | New compounds | |
| ATE171188T1 (de) | In 15-stellung substituierte 4-azasteroide | |
| NO944930L (no) | Hemming av dysfunksjonell uterin blödning | |
| MY128442A (en) | Diphenyl ether compounds useful in therapy | |
| DE3069813D1 (en) | Pharmaceutical composition containing a diphenylhydantoin derivative, derivatives used and their preparation | |
| SE0201194D0 (sv) | New compounds | |
| TW249804B (no) | ||
| NO944926L (no) | Fremgangsmåter for å inhibere myeloperoksidaseaktivitet | |
| CA2104456A1 (en) | Pyridine- and Imidazole-Derived Agents for Cardiovascular Diseases | |
| UA37311C2 (uk) | Засіб для лікування статевої дисфункції і фармацевтичний препарат | |
| ECSP941050A (es) | Derivados de benzofurano, proceso para su preparacion y composicion farmaceutica que los contiene | |
| IL106993A (en) | Benzenalkanoic acid derivatives and pharmaceutical compositions containing them |