SE461591B - Daunorubicin- och doxorubicin-analoger, deras framstaellning och terapeutisk komposition innehaallande dem - Google Patents

Daunorubicin- och doxorubicin-analoger, deras framstaellning och terapeutisk komposition innehaallande dem

Info

Publication number
SE461591B
SE461591B SE8300324A SE8300324A SE461591B SE 461591 B SE461591 B SE 461591B SE 8300324 A SE8300324 A SE 8300324A SE 8300324 A SE8300324 A SE 8300324A SE 461591 B SE461591 B SE 461591B
Authority
SE
Sweden
Prior art keywords
hydrogen
formula
daunorubicin
methyl
doxorubicin
Prior art date
Application number
SE8300324A
Other languages
English (en)
Swedish (sv)
Other versions
SE8300324D0 (sv
SE8300324L (sv
Inventor
S Penco
G Franchi
F Arcamone
A M Casazza
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of SE8300324D0 publication Critical patent/SE8300324D0/xx
Publication of SE8300324L publication Critical patent/SE8300324L/xx
Publication of SE461591B publication Critical patent/SE461591B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
SE8300324A 1982-01-26 1983-01-21 Daunorubicin- och doxorubicin-analoger, deras framstaellning och terapeutisk komposition innehaallande dem SE461591B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8202080 1982-01-26

Publications (3)

Publication Number Publication Date
SE8300324D0 SE8300324D0 (sv) 1983-01-21
SE8300324L SE8300324L (sv) 1983-07-27
SE461591B true SE461591B (sv) 1990-03-05

Family

ID=10527864

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8300324A SE461591B (sv) 1982-01-26 1983-01-21 Daunorubicin- och doxorubicin-analoger, deras framstaellning och terapeutisk komposition innehaallande dem

Country Status (28)

Country Link
JP (1) JPS58128396A (fr)
KR (1) KR900006214B1 (fr)
AT (1) AT378776B (fr)
AU (1) AU551700B2 (fr)
BE (1) BE895687A (fr)
CA (1) CA1197237A (fr)
CH (1) CH657622A5 (fr)
CS (1) CS235979B2 (fr)
DE (1) DE3301489A1 (fr)
DK (1) DK157322C (fr)
ES (1) ES519255A0 (fr)
FI (1) FI74977C (fr)
FR (1) FR2520365B1 (fr)
GB (1) GB2116169B (fr)
GR (1) GR77890B (fr)
HU (1) HU192784B (fr)
IE (1) IE53750B1 (fr)
IL (1) IL67709A (fr)
IT (1) IT1210482B (fr)
NL (1) NL8300150A (fr)
NO (1) NO153456C (fr)
NZ (1) NZ203047A (fr)
PH (1) PH19130A (fr)
PT (1) PT76113A (fr)
SE (1) SE461591B (fr)
SU (1) SU1187724A3 (fr)
YU (1) YU43536B (fr)
ZA (1) ZA83450B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2182926B (en) * 1985-11-19 1989-10-04 Erba Farmitalia Nitro anthracyclines, process for their preparation and use thereof
GB8708927D0 (en) * 1987-04-14 1987-05-20 Erba Farmitalia Chiral synthesis of anthracyclines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1509875A (en) * 1976-06-14 1978-05-04 Farmaceutici Italia Optically active anthracyclinones and anthracycline glycosides
GB1573037A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
EP0022515B1 (fr) * 1979-07-04 1983-08-03 FARMITALIA CARLO ERBA S.p.A. Anthracycline glycosides, procédé pour leur préparation et composition thérapeutique les contenant
DE3100968A1 (de) * 1980-01-16 1982-01-14 Farmitalia Carlo Erba S.p.A., 20159 Milano Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
GB2116169A (en) 1983-09-21
BE895687A (fr) 1983-05-16
AU551700B2 (en) 1986-05-08
SE8300324D0 (sv) 1983-01-21
KR840003262A (ko) 1984-08-20
DK157322C (da) 1990-05-07
CS235979B2 (en) 1985-05-15
JPS58128396A (ja) 1983-07-30
JPS6328436B2 (fr) 1988-06-08
GR77890B (fr) 1984-09-25
DE3301489A1 (de) 1983-08-04
PH19130A (en) 1986-01-08
AT378776B (de) 1985-09-25
FI74977C (fi) 1988-04-11
ATA15683A (de) 1985-02-15
IE830144L (en) 1983-07-26
NO153456B (no) 1985-12-16
PT76113A (en) 1983-02-01
NZ203047A (en) 1985-10-11
DK157322B (da) 1989-12-11
ZA83450B (en) 1983-10-26
YU43536B (en) 1989-08-31
NO830234L (no) 1983-07-27
DK27683D0 (da) 1983-01-25
NO153456C (no) 1986-03-26
AU1052583A (en) 1983-08-04
CH657622A5 (it) 1986-09-15
KR900006214B1 (ko) 1990-08-25
FI74977B (fi) 1987-12-31
NL8300150A (nl) 1983-08-16
DK27683A (da) 1983-07-27
ES8403140A1 (es) 1984-03-01
FI830155L (fi) 1983-07-27
FI830155A0 (fi) 1983-01-17
IE53750B1 (en) 1989-02-01
IL67709A0 (en) 1983-05-15
GB2116169B (en) 1985-09-04
CA1197237A (fr) 1985-11-26
IL67709A (en) 1986-03-31
DE3301489C2 (fr) 1988-01-28
IT1210482B (it) 1989-09-14
SU1187724A3 (ru) 1985-10-23
HU192784B (en) 1987-07-28
ES519255A0 (es) 1984-03-01
FR2520365B1 (fr) 1985-07-12
SE8300324L (sv) 1983-07-27
FR2520365A1 (fr) 1983-07-29
YU8983A (en) 1986-02-28
IT8319147A0 (it) 1983-01-18
GB8301178D0 (en) 1983-02-16

Similar Documents

Publication Publication Date Title
EP2223929A1 (fr) Dérivés et analogues de glycoside gambogique, procédé de préparation et utilisation de ceux-ci
HU200188B (en) Process for producing 4-demethoxy-4-amino-daunorubicin
PT89662B (pt) Processo para a preparacao de novos glicosidos antraciclinicos e de composicoes farmaceuticas que os contem
US5304687A (en) Morpholinyl derivatives of doxorubicin and process for their preparation
PT96226B (pt) Processo para a preparacao de derivados morfolinilicos de doxorubicina e de composicoes farmaceuticas que os contem
Penco et al. Synthesis, Antitumor Activity, and Cardiac Toxicity of New 4-Demethoxyanthracyclines¹
US4826964A (en) Bridged oxygen analogs of daunorubcin and doxorubicin
HU205132B (en) Process for producing fluorine-substituted epipodophyllotoxin glycosides and pharmaceutical compositions comprising same as active ingredient
US3758455A (en) Reof mycophenolic acid glucuronide and the process for the preparation the
SE461591B (sv) Daunorubicin- och doxorubicin-analoger, deras framstaellning och terapeutisk komposition innehaallande dem
FI78109B (fi) Foerfarande foer framstaellning av antracyklinglykosider.
EP0128670A1 (fr) Dérivés de 3-déméthoxy-3'-déamino-3'-(4-morpholinyl)anthracyclines à activité anticancer et antibiotique
Takai et al. Synthesis and antitumor activity of analogs of the antitumor antibiotic chartreusin
SE500732C2 (sv) Nya antracyklinglykosidderivat, förfarande för framställning därav samt farmaceutiska kompositioner därav
US4522815A (en) Anthracycline glycosides
JPH0778073B2 (ja) ニトロアントラサイクリン、その製造方法およびその使用
HU207734B (en) Process for producing phosphates and sulfates of 4'-demethyl-epipodophyl-lotoxin-glycozides and pharmaceutical compositions containing them
EP0683787B1 (fr) Derives de 4'-o-sulfonyl-anthracycline
FI89496B (fi) Foerfarande foer framstaellning av 4-demetoxi-4-aminoantracykliner
GB2034707A (en) Anthracycline glycosides
JPH0232260B2 (fr)
RO115525B1 (ro) Derivati de dizaharide ale antraciclinei procedeu pentru prepararea acestora si compozitie farmaceutica continand acesti derivati
MXPA01009025A (es) L-arabino-disacaridos de antraciclinas, proceso para su preparacion, y composiciones farmaceuticas que los contienen..
HU176452B (en) Process for preparing beta-daunosaminyl-nucleosides and pharmaceutical preparations containing thereof
KR20010013772A (ko) 13-디하이드로-3' 아지리디노 안트라사이클린

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 8300324-4

Effective date: 19910131

Format of ref document f/p: F