HU192784B - Process for producing daunorubicin and doxorubicin derivatives and pharmaceutical compositions containing them - Google Patents

Process for producing daunorubicin and doxorubicin derivatives and pharmaceutical compositions containing them Download PDF

Info

Publication number
HU192784B
HU192784B HU83240A HU24083A HU192784B HU 192784 B HU192784 B HU 192784B HU 83240 A HU83240 A HU 83240A HU 24083 A HU24083 A HU 24083A HU 192784 B HU192784 B HU 192784B
Authority
HU
Hungary
Prior art keywords
compound
hydrochloride
methoxy
leukemia
daunorubicin
Prior art date
Application number
HU83240A
Other languages
English (en)
Hungarian (hu)
Inventor
Penco
Franchi
Arcamone
Casazza
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of HU192784B publication Critical patent/HU192784B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
HU83240A 1982-01-26 1983-01-25 Process for producing daunorubicin and doxorubicin derivatives and pharmaceutical compositions containing them HU192784B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8202080 1982-01-26

Publications (1)

Publication Number Publication Date
HU192784B true HU192784B (en) 1987-07-28

Family

ID=10527864

Family Applications (1)

Application Number Title Priority Date Filing Date
HU83240A HU192784B (en) 1982-01-26 1983-01-25 Process for producing daunorubicin and doxorubicin derivatives and pharmaceutical compositions containing them

Country Status (28)

Country Link
JP (1) JPS58128396A (fr)
KR (1) KR900006214B1 (fr)
AT (1) AT378776B (fr)
AU (1) AU551700B2 (fr)
BE (1) BE895687A (fr)
CA (1) CA1197237A (fr)
CH (1) CH657622A5 (fr)
CS (1) CS235979B2 (fr)
DE (1) DE3301489A1 (fr)
DK (1) DK157322C (fr)
ES (1) ES8403140A1 (fr)
FI (1) FI74977C (fr)
FR (1) FR2520365B1 (fr)
GB (1) GB2116169B (fr)
GR (1) GR77890B (fr)
HU (1) HU192784B (fr)
IE (1) IE53750B1 (fr)
IL (1) IL67709A (fr)
IT (1) IT1210482B (fr)
NL (1) NL8300150A (fr)
NO (1) NO153456C (fr)
NZ (1) NZ203047A (fr)
PH (1) PH19130A (fr)
PT (1) PT76113A (fr)
SE (1) SE461591B (fr)
SU (1) SU1187724A3 (fr)
YU (1) YU43536B (fr)
ZA (1) ZA83450B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2182926B (en) * 1985-11-19 1989-10-04 Erba Farmitalia Nitro anthracyclines, process for their preparation and use thereof
GB8708927D0 (en) * 1987-04-14 1987-05-20 Erba Farmitalia Chiral synthesis of anthracyclines

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1509875A (en) * 1976-06-14 1978-05-04 Farmaceutici Italia Optically active anthracyclinones and anthracycline glycosides
GB1573037A (en) * 1977-05-05 1980-08-13 Farmaceutici Italia Anthracyclines
ATE4387T1 (de) * 1979-07-04 1983-08-15 Farmitalia Carlo Erba S.P.A. Anthracyclin-glycoside, verfahren zu ihrer herstellung und sie enthaltende therapeutische zusammensetzung.
DE3100968A1 (de) * 1980-01-16 1982-01-14 Farmitalia Carlo Erba S.p.A., 20159 Milano Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
SE8300324D0 (sv) 1983-01-21
NZ203047A (en) 1985-10-11
DK157322B (da) 1989-12-11
YU43536B (en) 1989-08-31
SE461591B (sv) 1990-03-05
GR77890B (fr) 1984-09-25
DK27683D0 (da) 1983-01-25
FR2520365B1 (fr) 1985-07-12
NO153456B (no) 1985-12-16
CS235979B2 (en) 1985-05-15
JPS58128396A (ja) 1983-07-30
IL67709A (en) 1986-03-31
CH657622A5 (it) 1986-09-15
KR840003262A (ko) 1984-08-20
IE830144L (en) 1983-07-26
JPS6328436B2 (fr) 1988-06-08
DE3301489A1 (de) 1983-08-04
AT378776B (de) 1985-09-25
FR2520365A1 (fr) 1983-07-29
GB8301178D0 (en) 1983-02-16
YU8983A (en) 1986-02-28
IE53750B1 (en) 1989-02-01
SE8300324L (sv) 1983-07-27
PH19130A (en) 1986-01-08
SU1187724A3 (ru) 1985-10-23
ES519255A0 (es) 1984-03-01
IT1210482B (it) 1989-09-14
NO830234L (no) 1983-07-27
FI830155L (fi) 1983-07-27
AU551700B2 (en) 1986-05-08
KR900006214B1 (ko) 1990-08-25
ZA83450B (en) 1983-10-26
NL8300150A (nl) 1983-08-16
GB2116169B (en) 1985-09-04
FI74977B (fi) 1987-12-31
FI830155A0 (fi) 1983-01-17
IT8319147A0 (it) 1983-01-18
FI74977C (fi) 1988-04-11
CA1197237A (fr) 1985-11-26
DK157322C (da) 1990-05-07
BE895687A (fr) 1983-05-16
GB2116169A (en) 1983-09-21
PT76113A (en) 1983-02-01
DK27683A (da) 1983-07-27
ES8403140A1 (es) 1984-03-01
DE3301489C2 (fr) 1988-01-28
NO153456C (no) 1986-03-26
AU1052583A (en) 1983-08-04
ATA15683A (de) 1985-02-15
IL67709A0 (en) 1983-05-15

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee