SE459639B - Foerfarande foer framstaellning av ett faktor viii (amf)-hoegkoncentrat - Google Patents

Foerfarande foer framstaellning av ett faktor viii (amf)-hoegkoncentrat

Info

Publication number
SE459639B
SE459639B SE8104482A SE8104482A SE459639B SE 459639 B SE459639 B SE 459639B SE 8104482 A SE8104482 A SE 8104482A SE 8104482 A SE8104482 A SE 8104482A SE 459639 B SE459639 B SE 459639B
Authority
SE
Sweden
Prior art keywords
precipitate
polyethylene glycol
subjected
ahf
fraction
Prior art date
Application number
SE8104482A
Other languages
English (en)
Swedish (sv)
Other versions
SE8104482L (sv
Inventor
Otto Schwarz
Yendra Linnau
Original Assignee
Immuno Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immuno Ag filed Critical Immuno Ag
Publication of SE8104482L publication Critical patent/SE8104482L/xx
Publication of SE459639B publication Critical patent/SE459639B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood
    • Y10S530/83—Plasma; serum
    • Y10S530/831—Cohn fractions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SE8104482A 1980-08-27 1981-07-22 Foerfarande foer framstaellning av ett faktor viii (amf)-hoegkoncentrat SE459639B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT0433880A AT369263B (de) 1980-08-27 1980-08-27 Verfahren zur herstellung eines faktor viii(ahf) -hochkonzentrates

Publications (2)

Publication Number Publication Date
SE8104482L SE8104482L (sv) 1982-02-28
SE459639B true SE459639B (sv) 1989-07-24

Family

ID=3562706

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8104482A SE459639B (sv) 1980-08-27 1981-07-22 Foerfarande foer framstaellning av ett faktor viii (amf)-hoegkoncentrat

Country Status (19)

Country Link
US (1) US4404131A (fr)
JP (1) JPS5928537B2 (fr)
AR (1) AR228874A1 (fr)
AT (1) AT369263B (fr)
BE (1) BE890003A (fr)
CA (1) CA1160567A (fr)
CH (1) CH652030A5 (fr)
DE (1) DE3129987C2 (fr)
DK (1) DK156764C (fr)
ES (1) ES8302017A1 (fr)
FI (1) FI72653C (fr)
FR (1) FR2489150A1 (fr)
GB (1) GB2083047B (fr)
HU (1) HU183542B (fr)
IT (1) IT1138511B (fr)
LU (1) LU83577A1 (fr)
NL (1) NL8103563A (fr)
NO (1) NO157884C (fr)
SE (1) SE459639B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU555305B2 (en) * 1982-09-29 1986-09-18 Bayer Corporation Antihemophilic factor concentrate
EP0148843B2 (fr) * 1983-03-21 1994-05-04 Novo Nordisk A/S Concentre du facteur antihemophilique viii et son procede de production
AT379510B (de) * 1983-05-20 1986-01-27 Immuno Ag Verfahren zur herstellung einer faktor viii (ahf) -haeltigen praeparation
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
US4710381A (en) * 1984-05-22 1987-12-01 The Blood Center Of Southeastern Wisconsin Method for maintaining intact, non-degraded factor VIII/von-Willebrand factor during blood processing
US5149787A (en) * 1984-05-22 1992-09-22 The Blood Center Research Foundation Method for maintaining intact, non-degraded factor VIII/von-Willebrand factor during blood processing
US4543210A (en) * 1984-10-04 1985-09-24 Miles Laboratories, Inc. Process for producing a high purity antihemophilic factor concentrate
US4847362A (en) * 1985-02-01 1989-07-11 New York University Method for purifying antihemophilic factor
US4952675A (en) * 1985-02-01 1990-08-28 New York University Method for purifying antihemophilic factor
US4743680A (en) * 1985-02-01 1988-05-10 New York University Method for purifying antihemophilic factor
CA1293941C (fr) * 1985-11-08 1992-01-07 Maria Erlinda Co-Sarno Methode pour preparer un facteur antihenophile (fah) par precipitation a froid et pour ameliorer la solubilite du fah recupere
WO1995003332A1 (fr) * 1993-07-23 1995-02-02 Baxter International Inc. Facteur viii humain active et procede de preparation
US5576291A (en) * 1993-09-13 1996-11-19 Baxter International Inc. Activated factor VIII as a therapeutic agent and method of treating factor VIII deficiency
US5659017A (en) * 1995-11-07 1997-08-19 Alpha Therapeutic Corporation Anion exchange process for the purification of Factor VIII
AU777972B2 (en) 1999-02-22 2004-11-04 Baxalta GmbH Novel albumin-free factor VIII formulations
US6893639B2 (en) * 2001-10-19 2005-05-17 Hemacare Corporation Method for high yield purification of immune globulins from blood plasma and blood plasma intermediates
JP5779780B2 (ja) * 2008-11-07 2015-09-16 バクスター・インターナショナル・インコーポレイテッドＢａｘｔｅｒ Ｉｎｔｅｒｎａｔｉｏｎａｌ Ｉｎｃｏｒｐ０Ｒａｔｅｄ 第ｖｉｉｉ因子製剤
CN116322920A (zh) 2020-11-09 2023-06-23 武田药品工业株式会社 使用氧化硅吸附从血浆中纯化fviii

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652530A (en) * 1967-08-28 1972-03-28 American Nat Red Cross Antihemophilic factor prepared from blood plasma using polyethylene glycol
US3631018A (en) * 1970-05-01 1971-12-28 Baxter Laboratories Inc Production of stable high-potency human ahf using polyethylene glycol and glycine to fractionate a cryoprecipitate of ahf concentrate
US3682881A (en) * 1970-10-02 1972-08-08 Baxter Laboratories Inc Fractionation of plasma using glycine and polyethylene glycol
US3869436A (en) * 1971-06-01 1975-03-04 Statens Bakteriologiska Lab Method for fractionating plasma proteins using peg and ion-exchangers
US4188318A (en) * 1975-06-16 1980-02-12 Edward Shanbrom Simplified method for preparation of high yield, high purity Factor VIII concentrate
US4069216A (en) * 1975-06-16 1978-01-17 Edward Shanbrom, Inc. Simplified methods for preparation of very high purity Factor VIII concentrate
CA1101332A (fr) * 1976-01-30 1981-05-19 Edward Shanbrom Procedes simplifies pour la preparation de concentres de facteur viii de tres grande purete
DE2624373C2 (de) 1976-05-31 1983-02-03 Arnold Dr. 8782 Karlstadt Seufert Verfahren zur Herstellung von steril filtriertem Kryopräzipilat mit einer Anreicherung des Faktors VIII
CA1054052A (fr) 1976-08-14 1979-05-08 Edward Shanbrom Methode simplifiee pour la preparation d'un concentre de facteur viii hautement purifie
FR2460305A2 (fr) * 1979-06-29 1981-01-23 Merieux Inst Procede de preparation d'un concentre de facteur viii

Also Published As

Publication number Publication date
ATA433880A (de) 1982-05-15
IT8123660A0 (it) 1981-08-27
SE8104482L (sv) 1982-02-28
FI812567L (fi) 1982-02-28
FR2489150B1 (fr) 1984-06-29
NO812905L (no) 1982-03-01
FR2489150A1 (fr) 1982-03-05
HU183542B (en) 1984-05-28
US4404131A (en) 1983-09-13
NO157884C (no) 1988-06-15
CH652030A5 (de) 1985-10-31
GB2083047B (en) 1984-03-28
NO157884B (no) 1988-02-29
DK156764B (da) 1989-10-02
BE890003A (fr) 1981-12-16
AR228874A1 (es) 1983-04-29
FI72653B (fi) 1987-03-31
GB2083047A (en) 1982-03-17
DE3129987A1 (de) 1982-04-22
AT369263B (de) 1982-12-27
LU83577A1 (de) 1981-12-01
IT1138511B (it) 1986-09-17
ES504859A0 (es) 1983-01-01
ES8302017A1 (es) 1983-01-01
DK156764C (da) 1990-02-19
DK360281A (da) 1982-02-28
DE3129987C2 (de) 1984-11-29
CA1160567A (fr) 1984-01-17
FI72653C (fi) 1987-07-10
NL8103563A (nl) 1982-03-16
JPS5775928A (en) 1982-05-12
JPS5928537B2 (ja) 1984-07-13

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