SE451143B - Forfarande for framstellning av insulinderivat - Google Patents

Forfarande for framstellning av insulinderivat

Info

Publication number
SE451143B
SE451143B SE8100928A SE8100928A SE451143B SE 451143 B SE451143 B SE 451143B SE 8100928 A SE8100928 A SE 8100928A SE 8100928 A SE8100928 A SE 8100928A SE 451143 B SE451143 B SE 451143B
Authority
SE
Sweden
Prior art keywords
insulin
thr
porcine
trypsin
threonine
Prior art date
Application number
SE8100928A
Other languages
English (en)
Swedish (sv)
Other versions
SE8100928L (sv
Inventor
J Markussen
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8095095&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE451143(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Industri As filed Critical Novo Industri As
Publication of SE8100928L publication Critical patent/SE8100928L/
Publication of SE451143B publication Critical patent/SE451143B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Forklifts And Lifting Vehicles (AREA)
SE8100928A 1980-02-11 1981-02-10 Forfarande for framstellning av insulinderivat SE451143B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK57480A DK147109C (da) 1980-02-11 1980-02-11 Fremgangsmaade til fremstilling af humant insulin eller humane insulinestere eller et salt eller kompleks deraf

Publications (2)

Publication Number Publication Date
SE8100928L SE8100928L (sv) 1981-08-12
SE451143B true SE451143B (sv) 1987-09-07

Family

ID=8095095

Family Applications (2)

Application Number Title Priority Date Filing Date
SE8100928A SE451143B (sv) 1980-02-11 1981-02-10 Forfarande for framstellning av insulinderivat
SE8100926A SE427025B (sv) 1980-02-11 1981-02-10 Gaffeltruck

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8100926A SE427025B (sv) 1980-02-11 1981-02-10 Gaffeltruck

Country Status (19)

Country Link
JP (1) JPS56135452A (fi)
AR (1) AR231277A1 (fi)
AU (1) AU541528B2 (fi)
BE (1) BE887480A (fi)
CA (1) CA1162868A (fi)
CH (1) CH655949A5 (fi)
DE (1) DE3104949C2 (fi)
DK (3) DK147109C (fi)
ES (1) ES499238A0 (fi)
FI (1) FI77876C (fi)
GB (1) GB2069502B (fi)
GR (1) GR73844B (fi)
IT (1) IT1195038B (fi)
NL (1) NL178797C (fi)
NO (1) NO156247C (fi)
NZ (1) NZ196224A (fi)
PT (1) PT72485B (fi)
SE (2) SE451143B (fi)
ZA (1) ZA81898B (fi)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK147437A (en) 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DE3101382A1 (de) * 1981-01-17 1982-09-02 Hoechst Ag, 6000 Frankfurt "verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten"
JPS58501455A (ja) * 1981-09-15 1983-09-01 ノルデイスク　インシユリンラボラトリユ−ム 人インシユリンまたはそのｂ−３０エステルの製造法
DK149824C (da) * 1982-01-22 1987-03-16 Carlsberg Biotechnology Ltd Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyrer i insuliner
WO1983002772A1 (en) * 1982-02-08 1983-08-18 Robin Ewart Offord An improved method for preparing human insulin from non-human insulin
DE3209184A1 (de) * 1982-03-13 1983-09-15 Hoechst Ag, 6230 Frankfurt Verfahren zur umwandlung von praeproinsulinanaloga zu insulinen
NL8201650A (nl) * 1982-04-21 1983-11-16 Akzo Nv Semisynthetische bereiding van humane insuline.
DE3381980D1 (de) * 1982-04-23 1990-12-13 Wako Pure Chem Ind Ltd Verfahren zur halbsynthese von menschlichem insulin und dazu zu verwendende alkalische protease.
DK55183D0 (da) * 1983-02-09 1983-02-09 Nordisk Insulinlab Fremgangsmade til fremstilling af human insulin
DE3334407A1 (de) * 1983-09-23 1985-04-04 Hoechst Ag, 6230 Frankfurt In position b 30 modifizierte insulin-derivate, verfahren zu deren herstellung und deren verwendung sowie pharmazeutische mittel zur behandlung des diabetes mellitus
DK119785D0 (da) * 1985-03-15 1985-03-15 Nordisk Gentofte Insulinpraeparat
US5157021A (en) * 1985-03-15 1992-10-20 Novo Nordisk A/S Insulin derivatives and pharmaceutical preparations containing these derivatives
SE449472B (sv) * 1985-10-15 1987-05-04 Mth Gruppen Ab Utrustning vid facklager
JP2606915B2 (ja) * 1987-02-25 1997-05-07 ノボ ノルディスク アクティーゼルスカブ 新規インシュリン誘導体
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
FI96503C (fi) * 1994-08-26 1996-07-10 Hymatic Ltd Oy Menetelmä ja laitteisto maston ohjaamiseksi
EP1711220A1 (en) 2004-01-16 2006-10-18 Biodel, Inc. Sublingual drug delivery device
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
US8084420B2 (en) 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
US7713929B2 (en) 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
MX2008013165A (es) 2006-04-12 2009-01-29 Biodel Inc Formulaciones de combinacion de insulina de accion rapida y accion larga.
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO153061C (no) * 1979-04-13 1986-01-08 Shionogi & Co Fremgangsmaate for fremstilling av et b30-threonininsulin
DK147437A (en) 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
DE3101382A1 (de) * 1981-01-17 1982-09-02 Hoechst Ag, 6000 Frankfurt "verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten"

Also Published As

Publication number Publication date
DK147437C (da) 1986-12-08
JPS56135452A (en) 1981-10-22
NZ196224A (en) 1984-08-24
FI77876C (fi) 1989-05-10
NL178797C (nl) 1986-05-16
DK147437A (en) 1900-01-01
GR73844B (fi) 1984-05-07
NO810443L (no) 1981-08-12
NL8100624A (nl) 1981-09-01
NL178797B (nl) 1985-12-16
AU541528B2 (en) 1985-01-10
DK147437B (da) 1984-08-06
DK147109B (da) 1984-04-09
PT72485A (en) 1981-03-01
DK57480A (da) 1981-08-12
DE3104949A1 (de) 1981-11-26
ES8205858A1 (es) 1982-08-01
JPH0211240B2 (fi) 1990-03-13
PT72485B (en) 1982-10-14
NO156247B (no) 1987-05-11
BE887480A (fr) 1981-08-11
DK147109C (da) 1986-12-08
AU6718081A (en) 1981-08-20
ES499238A0 (es) 1982-08-01
GB2069502B (en) 1984-08-08
DK54081A (da) 1981-08-12
CH655949A5 (de) 1986-05-30
IT8119620A0 (it) 1981-02-10
IT1195038B (it) 1988-09-28
IT8119620A1 (it) 1982-08-10
CA1162868A (en) 1984-02-28
NO156247C (no) 1987-08-19
SE8100928L (sv) 1981-08-12
ZA81898B (en) 1982-03-31
FI810385L (fi) 1981-08-12
SE427025B (sv) 1983-02-28
DE3104949C2 (de) 1984-04-26
AR231277A1 (es) 1984-10-31
FI77876B (fi) 1989-01-31
SE8100926L (sv) 1982-08-11
GB2069502A (en) 1981-08-26

Similar Documents

Publication Publication Date Title
SE451143B (sv) Forfarande for framstellning av insulinderivat
US4343898A (en) Process for preparing esters of human insulin
CA2464616C (en) Process for preparing insulin compounds
KR880001107B1 (ko) 인체 인슐린 및 그의 유도체의 제조방법
US4489159A (en) Process for preparing esters of human insulin
FI79853C (fi) Foerfarande foer framstaellning av insulinderivat.
EP0088117B1 (en) Process for preparing human insulin or b-30 esters thereof
US4801684A (en) Process for obtaining insulin precursors from reaction mixtures resulting from the folding of insulin precursors from the corresponding S-sulfonates
CA1154435A (en) Process for producing an insulin precursor
DK154573B (da) Fremgangsmaade til fremstilling af insuliner ud fra tilsvarende praeproinsulinanaloge
US4013628A (en) Process for the preparation of insulin, analogs and derivatives thereof
SE448303B (sv) Oxytocinanaloger med natriuretisk effekt
DK173007B1 (da) Fremgangsmåde til semisyntetisk fremstilling af humaninsulin og modificeret humaninsulin til brug ved fremgangsmåden
EP0087238A1 (en) Am improved method for preparing human insulin from non-human insulin
US3749704A (en) N-(omega-amino lower alkyl)-amides of 1,17-modified acth peptides
Schwartz et al. Glutamine B 16 insulin: Reduced insulin-like metabolic activity with moderately preserved mitogenic activity
LU83197A1 (de) Verfahren zur herstellung von threonin b30-estern menschlichen insulins sowie threonin b30-ester menschlichen insulins
USRE32015E (en) Process for the manufacture of insulin, analogs and derivatives thereof
Naithani et al. PROGRESS TOWARDS THE SEMISYNTHESIS OF PREPROINSULIN
DE2614259A1 (de) Radioaktiv markiertes jodiertes insulin und verfahren zu seiner herstellung
NO163531B (no) Beskyttet b30-thr(r1)(r2)-insulin egnet for fremstilling av et b30-threonininsulin.
WO1984003107A1 (en) A process for the preparation of human insulin

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8100928-4

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8100928-4

Format of ref document f/p: F