SE451073B - Forfarande for framstellning av insulinderivat - Google Patents

Forfarande for framstellning av insulinderivat

Info

Publication number
SE451073B
SE451073B SE8204627A SE8204627A SE451073B SE 451073 B SE451073 B SE 451073B SE 8204627 A SE8204627 A SE 8204627A SE 8204627 A SE8204627 A SE 8204627A SE 451073 B SE451073 B SE 451073B
Authority
SE
Sweden
Prior art keywords
acid
process according
reaction mixture
formula
trypsin
Prior art date
Application number
SE8204627A
Other languages
English (en)
Swedish (sv)
Other versions
SE8204627L (sv
SE8204627D0 (sv
Inventor
Jan Markussen
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Industri As filed Critical Novo Industri As
Publication of SE8204627D0 publication Critical patent/SE8204627D0/xx
Publication of SE8204627L publication Critical patent/SE8204627L/
Publication of SE451073B publication Critical patent/SE451073B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
SE8204627A 1981-08-10 1982-08-09 Forfarande for framstellning av insulinderivat SE451073B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK353781A DK353781A (da) 1981-08-10 1981-08-10 Fremgangsmaade til fremstilling af insulinderivater

Publications (3)

Publication Number Publication Date
SE8204627D0 SE8204627D0 (sv) 1982-08-09
SE8204627L SE8204627L (sv) 1983-02-11
SE451073B true SE451073B (sv) 1987-08-31

Family

ID=8124014

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8204627A SE451073B (sv) 1981-08-10 1982-08-09 Forfarande for framstellning av insulinderivat

Country Status (20)

Country Link
US (1) US4489159A (de)
JP (1) JPS5836399A (de)
AT (1) AT374683B (de)
AU (1) AU549066B2 (de)
BE (1) BE894070A (de)
CA (1) CA1174973A (de)
CH (1) CH661746A5 (de)
DE (1) DE3229674A1 (de)
DK (1) DK353781A (de)
ES (1) ES514845A0 (de)
FI (1) FI79142C (de)
FR (1) FR2511036B1 (de)
GB (1) GB2105342B (de)
GR (1) GR77999B (de)
IE (1) IE53712B1 (de)
IT (1) IT1152492B (de)
LU (1) LU84327A1 (de)
NL (1) NL182964C (de)
NO (1) NO157506C (de)
SE (1) SE451073B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776693A (en) * 1990-06-08 1998-07-07 Institut Pasteur Specific detection of the mycobacterium tuberculosis
JP2001521004A (ja) 1997-10-24 2001-11-06 イーライ・リリー・アンド・カンパニー 脂肪酸−アシル化インスリン類似体
CO4970787A1 (es) * 1997-12-23 2000-11-07 Lilly Co Eli Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea
US20080096800A1 (en) * 2004-03-12 2008-04-24 Biodel, Inc. Rapid mucosal gel or film insulin compositions
US20080090753A1 (en) 2004-03-12 2008-04-17 Biodel, Inc. Rapid Acting Injectable Insulin Compositions
US20080085298A1 (en) * 2004-03-12 2008-04-10 Biodel, Inc. Rapid Mucosal Gel or Film Insulin Compositions
US7713929B2 (en) * 2006-04-12 2010-05-11 Biodel Inc. Rapid acting and long acting insulin combination formulations
US8084420B2 (en) 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
JP2009533471A (ja) 2006-04-12 2009-09-17 バイオデル， インコーポレイテッド 即効型および長時間作用型組合せインスリン製剤
US9060927B2 (en) 2009-03-03 2015-06-23 Biodel Inc. Insulin formulations for rapid uptake
EP2451824A4 (de) * 2009-07-09 2013-04-24 Biocon Ltd Präparatives nichtlineares chromatographieverfahren auf gradientenbasis und gereinigte produkte daraus
US8883739B2 (en) 2010-01-19 2014-11-11 The Trustees Of Columbia University In The City Of New York Osteocalcin as a treatment for male reproductive disorders
US10052364B2 (en) 2013-03-15 2018-08-21 The Trustees Of Columbia University In The City Of New York Osteocalcin as a treatment for cognitive disorders
CN105849273B (zh) * 2013-12-23 2020-01-14 拜康研究有限公司 人胰岛素甲酯的生产方法
EP3581578A4 (de) * 2017-02-10 2020-04-22 Mitsubishi Chemical Corporation Trennmittel zur reinigung von menschlichem insulin und verfahren zur reinigung von menschlichem insulin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3276961A (en) * 1963-04-08 1966-10-04 Squibb & Sons Inc Process for preparing human insulin
US3903068A (en) * 1972-12-26 1975-09-02 Us Health Education & Welfare Facile synthesis of human insulin by modification of porcine insulin
NO153061C (no) * 1979-04-13 1986-01-08 Shionogi & Co Fremgangsmaate for fremstilling av et b30-threonininsulin
JPS55138392A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
US4343898A (en) * 1980-02-11 1982-08-10 Novo Industri A/S Process for preparing esters of human insulin
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
WO1983002772A1 (en) * 1982-02-08 1983-08-18 Robin Ewart Offord An improved method for preparing human insulin from non-human insulin

Also Published As

Publication number Publication date
AU549066B2 (en) 1986-01-09
AU8697482A (en) 1983-02-17
ES8306181A1 (es) 1983-05-01
FI79142B (fi) 1989-07-31
NO157506C (no) 1988-03-30
BE894070A (fr) 1983-02-09
IT1152492B (it) 1986-12-31
DE3229674A1 (de) 1983-02-17
GB2105342A (en) 1983-03-23
GB2105342B (en) 1985-06-26
FR2511036A1 (fr) 1983-02-11
CH661746A5 (de) 1987-08-14
FI822773L (fi) 1983-02-11
FI822773A0 (fi) 1982-08-09
IE53712B1 (en) 1989-01-18
JPS5836399A (ja) 1983-03-03
NO822704L (no) 1983-02-11
LU84327A1 (de) 1983-06-07
ATA303582A (de) 1983-10-15
AT374683B (de) 1984-05-25
IT8222784A0 (it) 1982-08-09
IE821911L (en) 1983-02-10
DE3229674C2 (de) 1992-07-09
NO157506B (no) 1987-12-21
SE8204627L (sv) 1983-02-11
SE8204627D0 (sv) 1982-08-09
NL8203137A (nl) 1983-03-01
CA1174973A (en) 1984-09-25
GR77999B (de) 1984-09-26
IT8222784A1 (it) 1984-02-09
NL182964C (nl) 1988-06-16
US4489159A (en) 1984-12-18
JPH0587239B2 (de) 1993-12-15
DK353781A (da) 1983-02-11
ES514845A0 (es) 1983-05-01
FR2511036B1 (fr) 1986-08-22
FI79142C (fi) 1989-11-10

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