SE450573B - 1h-pyrazolo/1,5-a/pyrimidiner, framstellning derav och farmaceutisk komposition - Google Patents
1h-pyrazolo/1,5-a/pyrimidiner, framstellning derav och farmaceutisk kompositionInfo
- Publication number
- SE450573B SE450573B SE8301412A SE8301412A SE450573B SE 450573 B SE450573 B SE 450573B SE 8301412 A SE8301412 A SE 8301412A SE 8301412 A SE8301412 A SE 8301412A SE 450573 B SE450573 B SE 450573B
- Authority
- SE
- Sweden
- Prior art keywords
- alkyl
- formula
- phenyl
- compound
- pyridyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8207637 | 1982-03-16 | ||
GB838303089A GB8303089D0 (en) | 1983-02-04 | 1983-02-04 | Substituted 1h-pyrazolo 1,5-a pyrimidines |
Publications (3)
Publication Number | Publication Date |
---|---|
SE8301412D0 SE8301412D0 (sv) | 1983-03-15 |
SE8301412L SE8301412L (sv) | 1983-09-17 |
SE450573B true SE450573B (sv) | 1987-07-06 |
Family
ID=26282260
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8301412A SE450573B (sv) | 1982-03-16 | 1983-03-15 | 1h-pyrazolo/1,5-a/pyrimidiner, framstellning derav och farmaceutisk komposition |
Country Status (13)
Country | Link |
---|---|
US (1) | US4482555A (de) |
AU (1) | AU557300B2 (de) |
CA (1) | CA1192546A (de) |
CH (1) | CH654306A5 (de) |
DE (1) | DE3309432A1 (de) |
DK (1) | DK120783A (de) |
FI (1) | FI74469C (de) |
FR (1) | FR2523582B1 (de) |
IL (1) | IL68133A (de) |
IT (1) | IT1194555B (de) |
NL (1) | NL8300934A (de) |
SE (1) | SE450573B (de) |
SU (1) | SU1366060A3 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6245759B1 (en) * | 1999-03-11 | 2001-06-12 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
MY125533A (en) | 1999-12-06 | 2006-08-30 | Bristol Myers Squibb Co | Heterocyclic dihydropyrimidine compounds |
EP1782859A3 (de) * | 2003-04-11 | 2009-09-30 | High Point Pharmaceuticals, LLC | Pharmazeutische Verwendung von Pyrazolo [1,5- a] Pyrimidin-Derivaten |
EP1615697A2 (de) * | 2003-04-11 | 2006-01-18 | Novo Nordisk A/S | Neue pyrazolo[1,5-a] pyrimidin-derivate und deren pharmazeutische verwendungen |
US7772232B2 (en) | 2004-04-15 | 2010-08-10 | Bristol-Myers Squibb Company | Quinazolinyl compounds as inhibitors of potassium channel function |
US8138342B2 (en) * | 2004-10-12 | 2012-03-20 | High Point Pharmacueticals, LLC | 11β-hydroxysteroid dehydrogenase type 1 active spiro compounds |
JP2009513611A (ja) * | 2005-11-01 | 2009-04-02 | ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー | 置換アミドの医薬用途 |
EP1948190A2 (de) * | 2005-11-01 | 2008-07-30 | Transtech Pharma | Pharmazeutische verwendung von substituierten amiden |
WO2007107550A1 (en) * | 2006-03-21 | 2007-09-27 | High Point Pharmaceuticals, Llc | Adamantane derivatives for the treatment of the metabolic syndrome |
CA2648074A1 (en) | 2006-04-07 | 2007-10-18 | High Point Pharmaceuticals, Llc | 11.beta.-hydroxysteroid dehydrogenase type 1 active compounds |
US20090306048A1 (en) * | 2006-06-16 | 2009-12-10 | John Paul Kilburn | Pharmaceutical use of substituted piperidine carboxamides |
EP1878721A1 (de) * | 2006-07-13 | 2008-01-16 | Novo Nordisk A/S | 4-Piperidylbenzamide als Inhibitoren der 11-beta-hydroxysteroiddehydrogenase Typ 1 |
EP2044073A1 (de) * | 2006-07-13 | 2009-04-08 | High Point Pharmaceuticals, LLC | Verbindungen mit wirkung an der 11beta-hydroxysteroiddehydrogenase vom typ 1 |
WO2008101886A1 (en) * | 2007-02-23 | 2008-08-28 | High Point Pharmaceuticals, Llc | N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase |
EA016951B1 (ru) | 2007-02-23 | 2012-08-30 | ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | N-АДАМАНТИЛБЕНЗАМИДЫ В КАЧЕСТВЕ ИНГИБИТОРОВ 11-β-ГИДРОКСИСТЕРОИДДЕГИДРОГЕНАЗЫ |
JP2010519242A (ja) * | 2007-02-23 | 2010-06-03 | ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー | 新規化合物 |
WO2008101885A1 (en) * | 2007-02-23 | 2008-08-28 | High Point Pharmaceuticals, Llc | N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase |
CN101652359A (zh) * | 2007-03-09 | 2010-02-17 | 高点制药有限责任公司 | 作为羟类固醇脱氢酶抑制剂的吲哚-和苯并咪唑酰胺类 |
CA2681934A1 (en) * | 2007-03-28 | 2008-10-02 | High Point Pharmaceuticals, Llc | 11beta-hsd1 active compounds |
ES2399912T3 (es) * | 2007-04-11 | 2013-04-04 | High Point Pharmaceuticals, Llc | Nuevos compuestos |
JP2010526777A (ja) * | 2007-04-24 | 2010-08-05 | ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー | 置換アミドの医薬用途 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE786611A (fr) * | 1971-08-16 | 1973-01-22 | Int Chem & Nuclear Corp | Nouveaux inhibiteurs de xanthine-oxydase et leur procede de preparatio |
US3907799A (en) * | 1971-08-16 | 1975-09-23 | Icn Pharmaceuticals | Xanthine oxidase inhibitors |
BE792533A (fr) * | 1971-12-09 | 1973-06-08 | Int Chem & Nuclear Corp | Nouvelles pyrazolo (1,5a) pyrimidines et leur procede de preparation |
US3925385A (en) * | 1972-04-20 | 1975-12-09 | Icn Pharmaceuticals | 6-Carbethoxy-3,7-disubstitutedpyrazolo{8 1,5a{9 pyrimidines |
US4093617A (en) * | 1974-11-12 | 1978-06-06 | Icn Pharmaceuticals, Inc. | 3,5,7-Trisubstituted pyrazolo[1,5-a]pyrimidines |
US4048184A (en) * | 1976-11-15 | 1977-09-13 | E. R. Squibb & Sons, Inc. | 6-Phenyl-2H-pyrazolo[3,4-b]pyridines |
US4281000A (en) * | 1979-07-09 | 1981-07-28 | American Cyanamid Company | Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents |
-
1983
- 1983-03-09 AU AU12304/83A patent/AU557300B2/en not_active Ceased
- 1983-03-10 US US06/474,205 patent/US4482555A/en not_active Expired - Fee Related
- 1983-03-11 CH CH1325/83A patent/CH654306A5/de not_active IP Right Cessation
- 1983-03-11 IT IT20024/83A patent/IT1194555B/it active
- 1983-03-15 SU SU833565748A patent/SU1366060A3/ru active
- 1983-03-15 FR FR8304253A patent/FR2523582B1/fr not_active Expired
- 1983-03-15 NL NL8300934A patent/NL8300934A/xx active Search and Examination
- 1983-03-15 CA CA000423644A patent/CA1192546A/en not_active Expired
- 1983-03-15 FI FI830864A patent/FI74469C/fi not_active IP Right Cessation
- 1983-03-15 IL IL68133A patent/IL68133A/xx unknown
- 1983-03-15 SE SE8301412A patent/SE450573B/sv not_active IP Right Cessation
- 1983-03-15 DK DK120783A patent/DK120783A/da not_active Application Discontinuation
- 1983-03-16 DE DE19833309432 patent/DE3309432A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
IL68133A (en) | 1985-12-31 |
CA1192546A (en) | 1985-08-27 |
DK120783D0 (da) | 1983-03-15 |
US4482555A (en) | 1984-11-13 |
FI74469B (fi) | 1987-10-30 |
FI830864L (fi) | 1983-09-17 |
FI830864A0 (fi) | 1983-03-15 |
CH654306A5 (de) | 1986-02-14 |
AU557300B2 (en) | 1986-12-18 |
FR2523582A1 (fr) | 1983-09-23 |
IL68133A0 (en) | 1983-06-15 |
FR2523582B1 (fr) | 1985-12-06 |
DK120783A (da) | 1983-09-17 |
FI74469C (fi) | 1988-02-08 |
SE8301412L (sv) | 1983-09-17 |
NL8300934A (nl) | 1983-10-17 |
IT1194555B (it) | 1988-09-22 |
DE3309432A1 (de) | 1983-09-22 |
IT8320024A0 (it) | 1983-03-11 |
SE8301412D0 (sv) | 1983-03-15 |
SU1366060A3 (ru) | 1988-01-07 |
AU1230483A (en) | 1983-09-22 |
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Legal Events
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NUG | Patent has lapsed |
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