IL68133A - 1-substituted-7-oxo-1h,7h-pyrazolo(1,5-a)pyrimidine-6-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

1-substituted-7-oxo-1h,7h-pyrazolo(1,5-a)pyrimidine-6-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL68133A
IL68133A IL68133A IL6813383A IL68133A IL 68133 A IL68133 A IL 68133A IL 68133 A IL68133 A IL 68133A IL 6813383 A IL6813383 A IL 6813383A IL 68133 A IL68133 A IL 68133A
Authority
IL
Israel
Prior art keywords
pyrazolo
pyrimidine
oxo
substituted
preparation
Prior art date
Application number
IL68133A
Other languages
English (en)
Other versions
IL68133A0 (en
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838303089A external-priority patent/GB8303089D0/en
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of IL68133A0 publication Critical patent/IL68133A0/xx
Publication of IL68133A publication Critical patent/IL68133A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IL68133A 1982-03-16 1983-03-15 1-substituted-7-oxo-1h,7h-pyrazolo(1,5-a)pyrimidine-6-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them IL68133A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8207637 1982-03-16
GB838303089A GB8303089D0 (en) 1983-02-04 1983-02-04 Substituted 1h-pyrazolo 1,5-a pyrimidines

Publications (2)

Publication Number Publication Date
IL68133A0 IL68133A0 (en) 1983-06-15
IL68133A true IL68133A (en) 1985-12-31

Family

ID=26282260

Family Applications (1)

Application Number Title Priority Date Filing Date
IL68133A IL68133A (en) 1982-03-16 1983-03-15 1-substituted-7-oxo-1h,7h-pyrazolo(1,5-a)pyrimidine-6-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them

Country Status (13)

Country Link
US (1) US4482555A (de)
AU (1) AU557300B2 (de)
CA (1) CA1192546A (de)
CH (1) CH654306A5 (de)
DE (1) DE3309432A1 (de)
DK (1) DK120783A (de)
FI (1) FI74469C (de)
FR (1) FR2523582B1 (de)
IL (1) IL68133A (de)
IT (1) IT1194555B (de)
NL (1) NL8300934A (de)
SE (1) SE450573B (de)
SU (1) SU1366060A3 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245759B1 (en) * 1999-03-11 2001-06-12 Merck & Co., Inc. Tyrosine kinase inhibitors
MY125533A (en) 1999-12-06 2006-08-30 Bristol Myers Squibb Co Heterocyclic dihydropyrimidine compounds
EP1782859A3 (de) * 2003-04-11 2009-09-30 High Point Pharmaceuticals, LLC Pharmazeutische Verwendung von Pyrazolo [1,5- a] Pyrimidin-Derivaten
EP1615697A2 (de) * 2003-04-11 2006-01-18 Novo Nordisk A/S Neue pyrazolo[1,5-a] pyrimidin-derivate und deren pharmazeutische verwendungen
US7772232B2 (en) 2004-04-15 2010-08-10 Bristol-Myers Squibb Company Quinazolinyl compounds as inhibitors of potassium channel function
US8138342B2 (en) * 2004-10-12 2012-03-20 High Point Pharmacueticals, LLC 11β-hydroxysteroid dehydrogenase type 1 active spiro compounds
JP2009513611A (ja) * 2005-11-01 2009-04-02 ハイ ポイント ファーマシューティカルズ，リミティド ライアビリティ カンパニー 置換アミドの医薬用途
EP1948190A2 (de) * 2005-11-01 2008-07-30 Transtech Pharma Pharmazeutische verwendung von substituierten amiden
WO2007107550A1 (en) * 2006-03-21 2007-09-27 High Point Pharmaceuticals, Llc Adamantane derivatives for the treatment of the metabolic syndrome
CA2648074A1 (en) 2006-04-07 2007-10-18 High Point Pharmaceuticals, Llc 11.beta.-hydroxysteroid dehydrogenase type 1 active compounds
US20090306048A1 (en) * 2006-06-16 2009-12-10 John Paul Kilburn Pharmaceutical use of substituted piperidine carboxamides
EP1878721A1 (de) * 2006-07-13 2008-01-16 Novo Nordisk A/S 4-Piperidylbenzamide als Inhibitoren der 11-beta-hydroxysteroiddehydrogenase Typ 1
EP2044073A1 (de) * 2006-07-13 2009-04-08 High Point Pharmaceuticals, LLC Verbindungen mit wirkung an der 11beta-hydroxysteroiddehydrogenase vom typ 1
WO2008101886A1 (en) * 2007-02-23 2008-08-28 High Point Pharmaceuticals, Llc N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase
EA016951B1 (ru) 2007-02-23 2012-08-30 ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи N-АДАМАНТИЛБЕНЗАМИДЫ В КАЧЕСТВЕ ИНГИБИТОРОВ 11-β-ГИДРОКСИСТЕРОИДДЕГИДРОГЕНАЗЫ
JP2010519242A (ja) * 2007-02-23 2010-06-03 ハイ ポイント ファーマシューティカルズ，リミティド ライアビリティ カンパニー 新規化合物
WO2008101885A1 (en) * 2007-02-23 2008-08-28 High Point Pharmaceuticals, Llc N-adamantyl benzamides as inhibitors of 11-beta-hydroxysteroid dehydrogenase
CN101652359A (zh) * 2007-03-09 2010-02-17 高点制药有限责任公司 作为羟类固醇脱氢酶抑制剂的吲哚-和苯并咪唑酰胺类
CA2681934A1 (en) * 2007-03-28 2008-10-02 High Point Pharmaceuticals, Llc 11beta-hsd1 active compounds
ES2399912T3 (es) * 2007-04-11 2013-04-04 High Point Pharmaceuticals, Llc Nuevos compuestos
JP2010526777A (ja) * 2007-04-24 2010-08-05 ハイ ポイント ファーマシューティカルズ，リミティド ライアビリティ カンパニー 置換アミドの医薬用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE786611A (fr) * 1971-08-16 1973-01-22 Int Chem & Nuclear Corp Nouveaux inhibiteurs de xanthine-oxydase et leur procede de preparatio
US3907799A (en) * 1971-08-16 1975-09-23 Icn Pharmaceuticals Xanthine oxidase inhibitors
BE792533A (fr) * 1971-12-09 1973-06-08 Int Chem & Nuclear Corp Nouvelles pyrazolo (1,5a) pyrimidines et leur procede de preparation
US3925385A (en) * 1972-04-20 1975-12-09 Icn Pharmaceuticals 6-Carbethoxy-3,7-disubstitutedpyrazolo{8 1,5a{9 pyrimidines
US4093617A (en) * 1974-11-12 1978-06-06 Icn Pharmaceuticals, Inc. 3,5,7-Trisubstituted pyrazolo[1,5-a]pyrimidines
US4048184A (en) * 1976-11-15 1977-09-13 E. R. Squibb & Sons, Inc. 6-Phenyl-2H-pyrazolo[3,4-b]pyridines
US4281000A (en) * 1979-07-09 1981-07-28 American Cyanamid Company Substituted pyrazolo (1,5-a)pyrimidines and their use as anxiolytic agents

Also Published As

Publication number Publication date
CA1192546A (en) 1985-08-27
DK120783D0 (da) 1983-03-15
US4482555A (en) 1984-11-13
FI74469B (fi) 1987-10-30
FI830864L (fi) 1983-09-17
FI830864A0 (fi) 1983-03-15
CH654306A5 (de) 1986-02-14
AU557300B2 (en) 1986-12-18
FR2523582A1 (fr) 1983-09-23
IL68133A0 (en) 1983-06-15
FR2523582B1 (fr) 1985-12-06
DK120783A (da) 1983-09-17
FI74469C (fi) 1988-02-08
SE8301412L (sv) 1983-09-17
NL8300934A (nl) 1983-10-17
IT1194555B (it) 1988-09-22
DE3309432A1 (de) 1983-09-22
IT8320024A0 (it) 1983-03-11
SE8301412D0 (sv) 1983-03-15
SU1366060A3 (ru) 1988-01-07
SE450573B (sv) 1987-07-06
AU1230483A (en) 1983-09-22

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