SE447540B - Sett att framstella pa oral veg administrerbara mikrokulor av fett, innehallande en mikroorganism - Google Patents
Sett att framstella pa oral veg administrerbara mikrokulor av fett, innehallande en mikroorganismInfo
- Publication number
- SE447540B SE447540B SE7909492A SE7909492A SE447540B SE 447540 B SE447540 B SE 447540B SE 7909492 A SE7909492 A SE 7909492A SE 7909492 A SE7909492 A SE 7909492A SE 447540 B SE447540 B SE 447540B
- Authority
- SE
- Sweden
- Prior art keywords
- fat
- microspheres
- dispersion
- temperature
- cncm
- Prior art date
Links
- 244000005700 microbiome Species 0.000 title claims description 22
- 239000004005 microsphere Substances 0.000 claims description 32
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 25
- 235000019197 fats Nutrition 0.000 claims description 18
- 239000006185 dispersion Substances 0.000 claims description 16
- 241000186000 Bifidobacterium Species 0.000 claims description 12
- 229910052757 nitrogen Inorganic materials 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 11
- 239000007788 liquid Substances 0.000 claims description 9
- 238000002844 melting Methods 0.000 claims description 9
- 230000008018 melting Effects 0.000 claims description 9
- 239000003795 chemical substances by application Substances 0.000 claims description 7
- 241001608472 Bifidobacterium longum Species 0.000 claims description 4
- 241000186015 Bifidobacterium longum subsp. infantis Species 0.000 claims description 4
- 241000186660 Lactobacillus Species 0.000 claims description 4
- 229940039696 lactobacillus Drugs 0.000 claims description 4
- 235000019871 vegetable fat Nutrition 0.000 claims description 3
- 241001133760 Acoelorraphe Species 0.000 claims description 2
- 235000017060 Arachis glabrata Nutrition 0.000 claims description 2
- 244000105624 Arachis hypogaea Species 0.000 claims description 2
- 235000010777 Arachis hypogaea Nutrition 0.000 claims description 2
- 235000018262 Arachis monticola Nutrition 0.000 claims description 2
- 240000002791 Brassica napus Species 0.000 claims description 2
- 235000004977 Brassica sinapistrum Nutrition 0.000 claims description 2
- 244000060011 Cocos nucifera Species 0.000 claims description 2
- 235000013162 Cocos nucifera Nutrition 0.000 claims description 2
- 235000010469 Glycine max Nutrition 0.000 claims description 2
- 241001465754 Metazoa Species 0.000 claims description 2
- 235000009470 Theobroma cacao Nutrition 0.000 claims description 2
- 244000299461 Theobroma cacao Species 0.000 claims description 2
- 235000020232 peanut Nutrition 0.000 claims description 2
- LWGJTAZLEJHCPA-UHFFFAOYSA-N n-(2-chloroethyl)-n-nitrosomorpholine-4-carboxamide Chemical compound ClCCN(N=O)C(=O)N1CCOCC1 LWGJTAZLEJHCPA-UHFFFAOYSA-N 0.000 claims 4
- 235000019737 Animal fat Nutrition 0.000 claims 1
- 240000001929 Lactobacillus brevis Species 0.000 claims 1
- 238000005054 agglomeration Methods 0.000 claims 1
- 230000002776 aggregation Effects 0.000 claims 1
- 241000700159 Rattus Species 0.000 description 9
- 239000000203 mixture Substances 0.000 description 5
- 239000007787 solid Substances 0.000 description 5
- 229920002494 Zein Polymers 0.000 description 4
- 239000001963 growth medium Substances 0.000 description 4
- 230000000968 intestinal effect Effects 0.000 description 4
- 239000005019 zein Substances 0.000 description 4
- 229940093612 zein Drugs 0.000 description 4
- 241001134770 Bifidobacterium animalis Species 0.000 description 3
- 210000003608 fece Anatomy 0.000 description 3
- 238000004519 manufacturing process Methods 0.000 description 3
- 210000002784 stomach Anatomy 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 241000186012 Bifidobacterium breve Species 0.000 description 2
- 239000002028 Biomass Substances 0.000 description 2
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 2
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 2
- XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 description 2
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 229940118852 bifidobacterium animalis Drugs 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 230000036760 body temperature Effects 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 239000008103 glucose Substances 0.000 description 2
- 239000004519 grease Substances 0.000 description 2
- 235000012054 meals Nutrition 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 235000018102 proteins Nutrition 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 241000251730 Chondrichthyes Species 0.000 description 1
- IMQLKJBTEOYOSI-UHFFFAOYSA-N Diphosphoinositol tetrakisphosphate Chemical compound OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O IMQLKJBTEOYOSI-UHFFFAOYSA-N 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 240000001046 Lactobacillus acidophilus Species 0.000 description 1
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 206010061876 Obstruction Diseases 0.000 description 1
- 235000019482 Palm oil Nutrition 0.000 description 1
- 108010073771 Soybean Proteins Proteins 0.000 description 1
- 239000005862 Whey Substances 0.000 description 1
- 102000007544 Whey Proteins Human genes 0.000 description 1
- 108010046377 Whey Proteins Proteins 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 229920006318 anionic polymer Polymers 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 238000000889 atomisation Methods 0.000 description 1
- 229940004120 bifidobacterium infantis Drugs 0.000 description 1
- 229940009291 bifidobacterium longum Drugs 0.000 description 1
- 238000007664 blowing Methods 0.000 description 1
- 229940041514 candida albicans extract Drugs 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 230000001143 conditioned effect Effects 0.000 description 1
- 239000002826 coolant Substances 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 description 1
- 235000018417 cysteine Nutrition 0.000 description 1
- 229910001873 dinitrogen Inorganic materials 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 239000000839 emulsion Substances 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 230000037406 food intake Effects 0.000 description 1
- 235000013350 formula milk Nutrition 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- WHWDWIHXSPCOKZ-UHFFFAOYSA-N hexahydrofarnesyl acetone Natural products CC(C)CCCC(C)CCCC(C)CCCC(C)=O WHWDWIHXSPCOKZ-UHFFFAOYSA-N 0.000 description 1
- 238000009396 hybridization Methods 0.000 description 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 229940039695 lactobacillus acidophilus Drugs 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000011325 microbead Substances 0.000 description 1
- 244000000010 microbial pathogen Species 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 239000002540 palm oil Substances 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 239000003223 protective agent Substances 0.000 description 1
- 235000020183 skimmed milk Nutrition 0.000 description 1
- 238000007711 solidification Methods 0.000 description 1
- 230000008023 solidification Effects 0.000 description 1
- 229940001941 soy protein Drugs 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 108010050327 trypticase-soy broth Proteins 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/745—Bifidobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/04—Making microcapsules or microballoons by physical processes, e.g. drying, spraying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dispersion Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH1239278A CH637297A5 (fr) | 1978-12-05 | 1978-12-05 | Microbille comprenant un microorganisme et son procede de fabrication. |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7909492L SE7909492L (sv) | 1980-06-06 |
| SE447540B true SE447540B (sv) | 1986-11-24 |
Family
ID=4382571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7909492A SE447540B (sv) | 1978-12-05 | 1979-11-16 | Sett att framstella pa oral veg administrerbara mikrokulor av fett, innehallande en mikroorganism |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4332790A (it) |
| AU (1) | AU526326B2 (it) |
| BE (1) | BE880027A (it) |
| CH (1) | CH637297A5 (it) |
| DE (1) | DE2946723C2 (it) |
| ES (1) | ES486575A1 (it) |
| FR (2) | FR2443247A1 (it) |
| IT (1) | IT1164075B (it) |
| MX (1) | MX6497E (it) |
| SE (1) | SE447540B (it) |
Families Citing this family (78)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4919929A (en) * | 1984-02-01 | 1990-04-24 | Stolle Research & Development Corporation | Mammal immunization |
| SE463598B (sv) * | 1984-11-08 | 1990-12-17 | Chemical Dynamics Sweden Ab | Preparat, avsett att oeka vidhaeftningen av bakterier till mag-tarmkanalen hos maenniskor och djur, samt ett framstaellningsfoerfarande foer detta |
| US5356625A (en) * | 1986-08-28 | 1994-10-18 | Enzacor Properties Limited | Microgranular preparation useful in the delivery of biologically active materials to the intestinal regions of animals |
| US5597564A (en) * | 1986-08-28 | 1997-01-28 | Enzacor Properties Limited | Method of administering a microgranular preparation to the intestinal region of animals |
| US6024983A (en) * | 1986-10-24 | 2000-02-15 | Southern Research Institute | Composition for delivering bioactive agents for immune response and its preparation |
| ATE165738T1 (de) * | 1988-08-02 | 1998-05-15 | Gastro Services Pty Ltd | Behandlung von gastro-intestinalen krankheiten |
| US5443826A (en) * | 1988-08-02 | 1995-08-22 | Borody; Thomas J. | Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli |
| AU640349B2 (en) * | 1988-08-02 | 1993-08-26 | Borody, Thomas J Dr | Treatment of gastro-intestinal disorders |
| EP0550436A1 (en) * | 1989-11-06 | 1993-07-14 | Alkermes Controlled Therapeutics, Inc. | Protein microspheres and methods of using them |
| US5213810A (en) * | 1990-03-30 | 1993-05-25 | American Cyanamid Company | Stable compositions for parenteral administration and method of making same |
| US5292657A (en) * | 1990-12-31 | 1994-03-08 | Pioneer Hi-Bred International, Inc. | Process for preparing rotary disc fatty acid microspheres of microorganisms |
| RU2096452C1 (ru) * | 1990-12-31 | 1997-11-20 | Пайонир Хай-Бред Интернэшнл, Инк. | Способ приготовления микрокапсул из бактерий в жирной кислоте и микрокапсула, содержащая лиофилизированную бактериальную культуру |
| US5599556A (en) * | 1991-12-31 | 1997-02-04 | Abbott Laboratories | Prolamine coatings for taste masking |
| ES2111625T3 (es) * | 1992-07-06 | 1998-03-16 | Nestle Sa | Agente antigastritis. |
| EP0577904B1 (fr) * | 1992-07-06 | 1997-05-14 | Societe Des Produits Nestle S.A. | Bactérie lactique |
| EP0654273A1 (en) * | 1993-11-18 | 1995-05-24 | Harry H. Leveen | Pharmaceutical product and method for treatment |
| US5733568A (en) * | 1993-12-03 | 1998-03-31 | Lafor Laboratories Limited | Micro-encapsulated lactobacilli for medical applications |
| ZA942302B (en) * | 1993-12-03 | 1995-09-29 | Lafor Lab Ltd | Viracidal bactericidal and spermicidal vaginal suppository |
| EP0858267A1 (de) * | 1995-11-02 | 1998-08-19 | Ed. Haas Nährmittel Gesellschaft m.b.H. | Probiotisch wirksame formulierungen |
| DK0818529T3 (da) * | 1996-07-09 | 2005-10-17 | Nestle Sa | Fremgangsmåde til spraytörring |
| US20020035071A1 (en) * | 1997-07-08 | 2002-03-21 | Josef Pitha | Mimicking the metabolic effects of caloric restriction by administration of glucose antimetabolites |
| US20060116330A1 (en) * | 1997-07-08 | 2006-06-01 | The Iams Company | Methods of mimicking the metabolic effects of caloric restriction by administration of mannoheptulose |
| US8563522B2 (en) * | 1997-07-08 | 2013-10-22 | The Iams Company | Method of maintaining and/or attenuating a decline in quality of life |
| CA2413109C (en) * | 2000-06-26 | 2007-11-27 | Martek Biosciences Boulder Corporation | Improved methods of incorporating polyunsaturated fatty acids in milk |
| AUPQ899700A0 (en) | 2000-07-25 | 2000-08-17 | Borody, Thomas Julius | Probiotic recolonisation therapy |
| RU2171672C1 (ru) * | 2000-08-31 | 2001-08-10 | Московская медицинская академия им. И.М. Сеченова | Способ получения микрокапсулированных форм лактобактерий |
| US20050266069A1 (en) * | 2002-09-06 | 2005-12-01 | Simmons Donald L | Stable probiotic microsphere compositions and their methods of preparation |
| US7517681B2 (en) * | 2003-01-29 | 2009-04-14 | Biogaia Ab | Selection and use of lactic acid bacteria for reducing dental caries and bacteria causing dental caries |
| US20050100559A1 (en) * | 2003-11-07 | 2005-05-12 | The Procter & Gamble Company | Stabilized compositions comprising a probiotic |
| US7785635B1 (en) * | 2003-12-19 | 2010-08-31 | The Procter & Gamble Company | Methods of use of probiotic lactobacilli for companion animals |
| US8877178B2 (en) * | 2003-12-19 | 2014-11-04 | The Iams Company | Methods of use of probiotic bifidobacteria for companion animals |
| US20050152884A1 (en) | 2003-12-19 | 2005-07-14 | The Procter & Gamble Company | Canine probiotic Bifidobacteria globosum |
| US20050158294A1 (en) * | 2003-12-19 | 2005-07-21 | The Procter & Gamble Company | Canine probiotic Bifidobacteria pseudolongum |
| US8894991B2 (en) * | 2003-12-19 | 2014-11-25 | The Iams Company | Canine probiotic Lactobacilli |
| DE102004004030A1 (de) * | 2004-01-27 | 2005-08-18 | Mars Inc. | Nahrungsmittelerzeugnis und Verfahren zu dessen Herstellung |
| CA2609617C (en) * | 2005-05-31 | 2014-07-08 | The Iams Company | Feline probiotic lactobacilli |
| AU2006253007B2 (en) * | 2005-05-31 | 2012-12-20 | Alimentary Health Ltd | Feline probiotic Bifidobacteria |
| US8221809B2 (en) * | 2006-06-22 | 2012-07-17 | Martek Biosciences Corporation | Encapsulated labile compound compositions and methods of making the same |
| RU2436581C2 (ru) | 2007-02-01 | 2011-12-20 | Дзе Иамс Компани | Способ уменьшения воспаления и снижения стресса у млекопитающего |
| BE1018007A5 (fr) * | 2008-02-21 | 2010-03-02 | Van Lidth De Jeude Jehan Lienart | Enrobage de microorganismes. |
| US9771199B2 (en) | 2008-07-07 | 2017-09-26 | Mars, Incorporated | Probiotic supplement, process for making, and packaging |
| SI2381799T1 (sl) * | 2009-01-27 | 2018-12-31 | Probiotical S.P.A. | Probiotični dodatek z okusom čokolade |
| IT1400821B1 (it) * | 2009-03-09 | 2013-07-02 | Probiotical Spa | Sospensione oleosa contenente batteri probiotici per uso pediatrico |
| EP2251021B1 (en) | 2009-05-11 | 2012-02-22 | Nestec S.A. | Prevention and treatment of allergic diarrhoea |
| US10104903B2 (en) | 2009-07-31 | 2018-10-23 | Mars, Incorporated | Animal food and its appearance |
| EP2289527B1 (en) | 2009-08-25 | 2018-02-21 | Nestec S.A. | Bifidobacterium longum and functional GI disorders |
| IT1398648B1 (it) * | 2010-03-09 | 2013-03-08 | Probiotical Spa | Prodotto alimentare comprendente batteri probiotici rivestiti con un rivestimento di origine vegetale. |
| NZ618935A (en) | 2010-08-04 | 2014-03-28 | Karma Medical Prod Co Ltd | Compositions for fecal floral transplantation and methods for making and using them and devices for delivering them |
| IT1403661B1 (it) | 2011-01-28 | 2013-10-31 | Probiotical Spa | Composizione effervescente in forma solida per uso in applicazioni vaginali per il trattamento di infezioni vaginali. |
| SG193348A1 (en) | 2011-03-09 | 2013-10-30 | Univ Minnesota | Compositions and methods for transplantation of colon microbiota |
| RU2572698C2 (ru) * | 2011-03-17 | 2016-01-20 | Пробиотикал С.п.А. | Пробиотические бактерии, обладающие антиоксидантной активностью, и их применение |
| ITMI20110791A1 (it) | 2011-05-09 | 2012-11-10 | Probiotical Spa | Ceppi di batteri in grado di metabolizzare gli ossalati. |
| ITMI20110793A1 (it) | 2011-05-09 | 2012-11-10 | Probiotical Spa | Ceppi di batteri probiotici e composizione sinbiotica contenente gli stessi destinata alla alimentazione dei neonati. |
| ITMI20110792A1 (it) | 2011-05-09 | 2012-11-10 | Probiotical Spa | Ceppi di batteri appartenenti al genere bifidobacterium per uso nel trattamento della ipercolesterolemia. |
| ITRM20110477A1 (it) | 2011-09-09 | 2013-03-10 | Giovanni Mogna | Composizione comprendente n-acetilcisteina e/o lisozima microincapsulato gastroprotetto in associazione con batteri probiotici in grado di ripristinare l'effetto barriera proprio dello stomaco che viene perso durante il trattamento farmacologico dell |
| ITMI20111718A1 (it) | 2011-09-23 | 2013-03-24 | Probiotical Spa | Un materiale impermeabile alla umidita e allo ossigeno per confezionare prodotti dietetici, cosmetici e specialita medicinali. |
| DE102012008271A1 (de) | 2012-04-23 | 2013-10-24 | Human Nutrition Gmbh | Kleingebäck zur Unterstützung der Gewichtsreduktion |
| US9719144B2 (en) | 2012-05-25 | 2017-08-01 | Arizona Board Of Regents | Microbiome markers and therapies for autism spectrum disorders |
| CN103622917B (zh) * | 2012-08-23 | 2017-12-29 | 尼奥克斯(文莱)控股有限公司 | 基于微囊化亚硝酸盐和酸化水凝胶的延时产生一氧化氮的系统和方法 |
| ITMI20130793A1 (it) | 2013-05-14 | 2014-11-15 | Probiotical Spa | Composizione comprendente batteri lattici per uso nel trattamento preventivo e/o curativo delle cistiti ricorrenti. |
| BR112017024264B1 (pt) | 2015-05-14 | 2022-07-12 | Crestovo Holdings Llc | Composições para transplante de flora fecal e métodos de preparação e utilização das mesmas, e dispositivos para sua administração |
| EP3998072A1 (en) | 2015-05-22 | 2022-05-18 | Arizona Board of Regents on behalf of Arizona State University | Methods for treating autism spectrum disorder and associated symptoms |
| MA45334A (fr) | 2016-03-24 | 2019-01-30 | Probiotical Spa | Composition bactérienne d'acide lactique pour le traitement d'infections vaginales bactériennes par gardnerella vaginalis et, éventuellement, d'infections fongiques concurrentes |
| US20170360848A1 (en) | 2016-06-15 | 2017-12-21 | Arizona Board Of Regents On Behalf Of Arizona State University | Methods for treating autism spectrum disorder and associated symptoms |
| US10849936B2 (en) | 2016-07-01 | 2020-12-01 | Regents Of The University Of Minnesota | Compositions and methods for C. difficile treatment |
| US20180036352A1 (en) | 2016-08-03 | 2018-02-08 | Crestovo Holdings Llc | Methods for treating ulcerative colitis |
| WO2018071536A1 (en) | 2016-10-11 | 2018-04-19 | Crestovo Holdings Llc | Compositions and methods for treating primary sclerosing cholangitis and related disorders |
| US10092601B2 (en) | 2016-10-11 | 2018-10-09 | Crestovo Holdings Llc | Compositions and methods for treating multiple sclerosis and related disorders |
| US11026978B2 (en) | 2016-10-11 | 2021-06-08 | Finch Therapeutics Holdings Llc | Compositions and methods for treating multiple sclerosis and related disorders |
| US11040073B2 (en) | 2017-04-05 | 2021-06-22 | Finch Therapeutics Holdings Llc | Compositions and methods for treating diverticulitis and related disorders |
| EP3606541A1 (en) | 2017-04-05 | 2020-02-12 | Crestovo Holdings LLC | Compositions and methods for treating parkinson's disease (pd) and related disorders |
| CA3064773A1 (en) | 2017-05-26 | 2018-11-29 | Crestovo Holdings Llc | Lyophilized compositions comprising fecal microbe-based therapeutic agents and methods for making and using same |
| US11865145B2 (en) | 2017-08-07 | 2024-01-09 | Finch Therapeutics Holdings Llc | Compositions and methods for maintaining and restoring a healthy gut barrier |
| US11166990B2 (en) | 2018-07-13 | 2021-11-09 | Finch Therapeutics Holdings Llc | Methods and compositions for treating ulcerative colitis |
| CN113164527A (zh) | 2018-09-27 | 2021-07-23 | 芬奇治疗控股有限责任公司 | 用于治疗癫痫和相关障碍的组合物和方法 |
| JP7296454B2 (ja) | 2018-10-02 | 2023-06-22 | ソシエテ・デ・プロデュイ・ネスレ・エス・アー | 炎症関連胃腸障害の処置のためのプロバイオティクスの組み合わせ |
| US20220000947A1 (en) | 2018-12-21 | 2022-01-06 | Société des Produits Nestlé S.A. | Probiotic combination for treatment of allergic disorders |
| CA3147629A1 (en) | 2019-07-19 | 2021-01-28 | Finch Therapeutics Holdings Llc. | Methods and products for treatment of gastrointestinal disorders |
Family Cites Families (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US952418A (en) * | 1909-08-14 | 1910-03-15 | Emil Collett | Dietetic chocolate and cocoa. |
| US1758937A (en) * | 1925-12-05 | 1930-05-20 | George H Earp-Thomas | Lactobacteria product |
| US1851165A (en) * | 1927-05-16 | 1932-03-29 | Stewart M Farr | Lactobacillus acidophilus milk product and its method of manufacture |
| US1929085A (en) * | 1932-12-01 | 1933-10-03 | Erwin A A Suehs | Method of preserving viable bacilli |
| US2369218A (en) * | 1941-01-02 | 1945-02-13 | George F Dick | Preparations of scarlet fever toxin for administration by mouth |
| US2376333A (en) * | 1941-02-03 | 1945-05-22 | Univ California | Method of preserving microorganisms |
| FR1128072A (fr) * | 1955-06-22 | 1957-01-02 | Biotic | Procédé pour la préparation de cultures microbiennes destinées à être conservées |
| US2875130A (en) * | 1956-11-20 | 1959-02-24 | Smith Kline French Lab | Method of preparing sustained release particles and the product of the method |
| GB825480A (en) * | 1957-07-13 | 1959-12-16 | Johann Carl Pflueger | Improvements in or relating to ingestible dry micro-organism preparations and method for producing the same |
| US3265629A (en) * | 1958-12-22 | 1966-08-09 | Ncr Co | Coating by phase separation |
| FR1290858A (fr) * | 1961-02-08 | 1962-04-20 | Franscoma | Appareil destiné à la pulvérisation de produits ou de mélanges de produits solides |
| BE640616A (it) * | 1962-12-19 | |||
| FR2828M (fr) * | 1963-03-01 | 1964-11-02 | Lucien Nouvel | Médicament renfermant des colibacilles antibiorésistants. |
| FR3626M (fr) * | 1963-11-13 | 1965-10-18 | Lucien Nouvel | Médicament pour affections intestinales. |
| FR1398107A (fr) * | 1964-03-26 | 1965-05-07 | Produit auxiliaire pour la fabrication des pâtes | |
| US4132753A (en) * | 1965-02-12 | 1979-01-02 | American Cyanamid Company | Process for preparing oral sustained release granules |
| FR1514115A (fr) * | 1966-08-19 | 1968-02-23 | Procédé de conservation des bactéries et produits en résultant | |
| FR1495040A (fr) * | 1966-08-24 | 1967-12-18 | Interfett Spezialfettprodukte | Procédé et dispositifs pour transformer des graisses et des mélanges d'huiles et de graisses en une poudre fine à structure cristalline |
| FR1584757A (it) * | 1967-06-01 | 1970-01-02 | ||
| GB1271674A (en) | 1968-07-09 | 1972-04-26 | Nisshin Flour Milling Co | Process and preparation for treating diarrhoea in pigs |
| FR1602543A (en) * | 1968-10-28 | 1970-12-21 | Therapeutic compns contng freeze dried bacteria | |
| US3541204A (en) * | 1968-12-02 | 1970-11-17 | Ian Ramsay Sibbald | Encapsulated biologically active materials for feeding to ruminants and process for the production thereof |
| US3856699A (en) * | 1969-08-08 | 1974-12-24 | Fuji Photo Film Co Ltd | Process for producing capsules having walls of a waxy material |
| US3892880A (en) * | 1969-08-19 | 1975-07-01 | Erhard Grolitsch | Method for the manufacture of crystalline, flowable, stable fat powders or mixtures of such fat powders with other powdery materials |
| JPS4910912B1 (it) * | 1970-03-17 | 1974-03-13 | ||
| JPS4945224B1 (it) * | 1970-12-14 | 1974-12-03 | ||
| US3959493A (en) * | 1971-03-17 | 1976-05-25 | Rumen Chemie, Ag | Rumen bypass products comprising biologically active substances protected with aliphatic fatty acids |
| BE788554A (fr) * | 1971-09-23 | 1973-01-02 | Rech Applic Scient Sogeras S A | Procede pour la fabrication de substances actives pulverisees protegeescontre un milieu biologique |
| US3823228A (en) * | 1971-09-29 | 1974-07-09 | Univ Illinois | Tge virus vaccine |
| DE2209565A1 (de) * | 1972-02-29 | 1973-09-13 | Lothringer Muehlen Gmbh | Verfahren und vorrichtung zur herstellung eines fettkonzentrates |
| FR2201837A1 (en) * | 1972-07-31 | 1974-05-03 | Petroles Cie Francaise | Powdered milk substitutes - contg powdered protein-rich fermented micro-organism prod esp for animal feed |
| DE2253515C3 (de) * | 1972-10-28 | 1978-07-06 | Fa. E. Kampffmeyer, 2000 Hamburg | Verfahren zur Überführung von geschmolzenen Substanzen, insbesondere von Fetten und Fettgemischen in pulverförmige Konzentrate durch Versprühen |
| GB1413186A (en) * | 1973-06-27 | 1975-11-12 | Toyo Jozo Kk | Process for encapsulation of medicaments |
| US3957974A (en) * | 1974-11-05 | 1976-05-18 | Seikenkai | Method for deodorization of excrements |
| JPS5231981A (en) * | 1975-08-18 | 1977-03-10 | Takeda Chem Ind Ltd | Microcapsule preparation method |
| US3973053A (en) * | 1975-09-24 | 1976-08-03 | Scm Corporation | Process for tempering beaded fat quickly |
| SU598629A1 (ru) | 1976-08-16 | 1978-03-25 | Московский Ордена Ленина И Ордена Трудового Красного Знамени Государственный Университет Им. М.В.Ломоносова | Способ получени микрокапсул |
| DE2645444A1 (de) | 1976-10-08 | 1978-04-13 | Karl Dr Med Theurer | Verfahren zur gewinnung von oral wirksamen arzneimitteln und impfstoffen aus primaer nicht darmwirksamen praeparaten |
| US4147773A (en) * | 1977-12-12 | 1979-04-03 | Morinaga Milk Industry Co., Ltd. | Powdery composition comprising viable Bifidobacteria cells and lactulose |
| US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
-
1978
- 1978-12-05 CH CH1239278A patent/CH637297A5/fr not_active IP Right Cessation
-
1979
- 1979-01-03 FR FR7900086A patent/FR2443247A1/fr active Granted
- 1979-06-29 FR FR7916870A patent/FR2443279A1/fr active Granted
- 1979-11-14 BE BE0/198101A patent/BE880027A/fr not_active IP Right Cessation
- 1979-11-16 SE SE7909492A patent/SE447540B/sv not_active IP Right Cessation
- 1979-11-20 DE DE2946723A patent/DE2946723C2/de not_active Expired
- 1979-11-23 US US06/096,771 patent/US4332790A/en not_active Expired - Lifetime
- 1979-11-27 MX MX798500U patent/MX6497E/es unknown
- 1979-11-29 AU AU53298/79A patent/AU526326B2/en not_active Ceased
- 1979-12-03 IT IT50976/79A patent/IT1164075B/it active
- 1979-12-04 ES ES486575A patent/ES486575A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CH637297A5 (fr) | 1983-07-29 |
| US4332790A (en) | 1982-06-01 |
| AU5329879A (en) | 1980-07-10 |
| FR2443279A1 (fr) | 1980-07-04 |
| FR2443279B1 (it) | 1984-04-06 |
| FR2443247A1 (fr) | 1980-07-04 |
| DE2946723C2 (de) | 1987-04-09 |
| FR2443247B1 (it) | 1983-04-29 |
| SE7909492L (sv) | 1980-06-06 |
| BE880027A (fr) | 1980-05-14 |
| ES486575A1 (es) | 1980-10-01 |
| IT7950976A0 (it) | 1979-12-03 |
| MX6497E (es) | 1985-06-21 |
| AU526326B2 (en) | 1983-01-06 |
| IT1164075B (it) | 1987-04-08 |
| DE2946723A1 (de) | 1980-06-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SE447540B (sv) | Sett att framstella pa oral veg administrerbara mikrokulor av fett, innehallande en mikroorganism | |
| Yoha et al. | Targeted delivery of probiotics: perspectives on research and commercialization | |
| Fávaro-Trindade et al. | Microencapsulation of L. acidophilus (La-05) and B. lactis (Bb-12) and evaluation of their survival at the pH values of the stomach and in bile | |
| Anal et al. | Recent advances in microencapsulation of probiotics for industrial applications and targeted delivery | |
| Serna-Cock et al. | Probiotic encapsulation | |
| EP1667696B1 (en) | Probiotic storage and delivery | |
| Seth et al. | Effect of microencapsulation using extrusion technique on viability of bacterial cells during spray drying of sweetened yoghurt | |
| Hernández-López et al. | Optimization of a spray-drying process for the production of maximally viable microencapsulated Lactobacillus pentosus using a mixture of starch-pulque as wall material | |
| JP2006501281A (ja) | 油乳化プロバイオティックカプセル封入物のプレバイオティックおよび保存的使用 | |
| WO2017137496A1 (en) | Multilayer probiotic microcapsules | |
| Varankovich et al. | Evaluation of pea protein–polysaccharide matrices for encapsulation of acid-sensitive bacteria | |
| Barro et al. | Microencapsulation of probiotic Lactobacillus helveticus with different wall materials by spray drying | |
| Xie et al. | Whey protein hydrolysates as prebiotic and protective agent regulate growth and survival of Lactobacillus rhamnosus CICC22152 during spray/freeze‐drying, storage and gastrointestinal digestion | |
| Ji et al. | Microencapsulation of Bacillus smithii XY1 by spray drying and evaluation for treatment of inflammatory bowel disease | |
| D'Alessandro et al. | Unravelling the functional and technological potential of soy milk based microencapsulated Lactobacillus crispatus and Lactobacillus gasseri | |
| Pandey et al. | Encapsulation of probiotic bacillus coagulans for enhanced shelf life | |
| Panjanapongchai et al. | Microencapsulation of probiotics and its potential industrial applications | |
| Mohammad et al. | Biopolymeric encapsulation of probiotics for improved release properties in the gastrointestinal digestion system | |
| Gullifa et al. | Innovative microencapsulation strategy to produce probiotic based products with a dual impact on human heath | |
| WO2011122934A2 (en) | Bioencapsule and method thereof | |
| US20250019643A1 (en) | Improved stability of microbial composition, and manufacturing methods therefore | |
| Setiarto et al. | Modified taro starch as alternative encapsulant for microencapsulation of Lactobacillus plantarum SU-LS 36 | |
| Dam et al. | Effect of starch and glycerol on the properties of alginate-microcapsules creating by phase separation coacervation method | |
| US20250019639A1 (en) | Fat and wax microencapsulated ambient stable bacteria and probiotics | |
| US20250011709A1 (en) | Compositions for increased stabitlity of bacteria |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAL | Patent in force |
Ref document number: 7909492-6 Format of ref document f/p: F |
|
| NUG | Patent has lapsed |
Ref document number: 7909492-6 Format of ref document f/p: F |