SE431650B - Indolo (2,3-a) kinolizidiner och sett att framstella dessa - Google Patents

Indolo (2,3-a) kinolizidiner och sett att framstella dessa

Info

Publication number
SE431650B
SE431650B SE7906287A SE7906287A SE431650B SE 431650 B SE431650 B SE 431650B SE 7906287 A SE7906287 A SE 7906287A SE 7906287 A SE7906287 A SE 7906287A SE 431650 B SE431650 B SE 431650B
Authority
SE
Sweden
Prior art keywords
group
indole
product
ethyl
quinolizidine
Prior art date
Application number
SE7906287A
Other languages
English (en)
Swedish (sv)
Other versions
SE7906287L (sv
Inventor
Andre Buzas
Original Assignee
Andre Buzas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Andre Buzas filed Critical Andre Buzas
Publication of SE7906287L publication Critical patent/SE7906287L/xx
Publication of SE431650B publication Critical patent/SE431650B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14Radicals substituted by nitrogen atoms, not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
SE7906287A 1977-11-25 1979-07-23 Indolo (2,3-a) kinolizidiner och sett att framstella dessa SE431650B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4920177 1977-11-25

Publications (2)

Publication Number Publication Date
SE7906287L SE7906287L (sv) 1979-07-23
SE431650B true SE431650B (sv) 1984-02-20

Family

ID=10451538

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7906287A SE431650B (sv) 1977-11-25 1979-07-23 Indolo (2,3-a) kinolizidiner och sett att framstella dessa
SE8007845A SE435622B (sv) 1977-11-25 1980-11-07 Terapeutisk komposition innehallande indolo(2,3-a)kinolizidiner

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8007845A SE435622B (sv) 1977-11-25 1980-11-07 Terapeutisk komposition innehallande indolo(2,3-a)kinolizidiner

Country Status (28)

Country Link
JP (1) JPS6147838B2 (it)
AR (1) AR218514A1 (it)
AT (1) AT372384B (it)
AU (1) AU529108B2 (it)
BE (1) BE872134A (it)
CA (1) CA1100959A (it)
CH (1) CH641181A5 (it)
DE (1) DE2851028A1 (it)
DK (1) DK154430C (it)
EG (1) EG13683A (it)
ES (1) ES475328A1 (it)
FI (1) FI64372C (it)
FR (2) FR2423492A1 (it)
HK (1) HK60884A (it)
IE (1) IE47518B1 (it)
IN (1) IN151146B (it)
IT (1) IT1160263B (it)
LU (1) LU80576A1 (it)
MX (1) MX5529E (it)
MY (1) MY8500029A (it)
NL (1) NL7811562A (it)
NO (1) NO151288C (it)
NZ (1) NZ188974A (it)
PT (1) PT68825A (it)
SE (2) SE431650B (it)
SG (1) SG61182G (it)
WO (1) WO1979000319A1 (it)
ZA (1) ZA786426B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0079411B1 (fr) * 1981-11-18 1987-02-04 Thal, Claude Dérivés d'indoloquinolizine, leur procédé de préparation et leur application en thérapeutique
FR2529552B1 (fr) * 1982-07-05 1985-09-27 Centre Nat Rech Scient Nouveau procede de preparation d'intermediaires de synthese de la vindoline et intermediaires de synthese
HU191454B (en) * 1984-10-05 1987-02-27 Richter Gedeon Vegyeszeti Gyar Rt.,Hu Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
FI95572C (fi) 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
PT704439E (pt) * 1993-06-18 2001-12-28 Fujisawa Pharmaceutical Co Novo intermediario para utilizacao sintetica e processo para a preparacao de derivados de aminopiperazina
FR2713643B1 (fr) * 1993-12-14 1996-06-07 Adir Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2713644B1 (fr) * 1993-12-14 1996-02-09 Adir Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
CA2490055C (fr) 2002-06-24 2011-10-18 Saint-Gobain Isover Panneau d'isolation pour conduit de distribution
FR2911141B1 (fr) * 2007-01-05 2009-02-20 Servier Lab Nouveaux derives triazabenzo[a]naphtho[2,1,8-cde]azulene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2911142A1 (fr) * 2007-01-05 2008-07-11 Servier Lab Nouveaux derives aminopyrrolo[1,2-a]indole et aminopyridazino[1,6-a]indole,leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2911143A1 (fr) * 2007-01-05 2008-07-11 Servier Lab Utilisation de composes neuroprotecteurs pour l'obtention de medicaments destines au traitement de maladies neurodegeneratives.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU167366B (it) * 1972-09-06 1975-09-27
BE802387A (fr) * 1973-07-16 1973-11-16 Omnium Chimique Sa Procede de preparation de la vincamone et de l'epi-21 vincamone a partir de la tabersonine et derives indoliques nouveaux.
HU169916B (it) * 1974-09-27 1977-02-28
HU171165B (hu) * 1974-11-26 1977-11-28 Richter Gedeon Vegyeszet Sposob poluchenija proizvodnykh oktagidro-indolo-skobka-2,3-a-skobka zakryta-kinolizina
FR2315277A1 (fr) * 1975-06-25 1977-01-21 Anvar Nouveaux derives pentacycliques, leur preparation et les compositions qui les contiennent

Also Published As

Publication number Publication date
ZA786426B (en) 1979-10-31
FR2409755B1 (it) 1980-08-01
DK524978A (da) 1979-05-26
PT68825A (en) 1978-12-01
HK60884A (en) 1984-08-10
DK154430B (da) 1988-11-14
JPS54500053A (it) 1979-11-08
IE47518B1 (en) 1984-04-04
AU4187478A (en) 1979-05-31
FR2423492A1 (fr) 1979-11-16
NL7811562A (nl) 1979-05-29
ATA837478A (de) 1983-02-15
FI783581A (fi) 1979-05-26
WO1979000319A1 (fr) 1979-06-14
MX5529E (es) 1983-09-23
EG13683A (en) 1982-09-30
IE782328L (en) 1979-05-25
CH641181A5 (fr) 1984-02-15
AU529108B2 (en) 1983-05-26
DK154430C (da) 1989-04-17
NO151288C (no) 1985-03-13
JPS6147838B2 (it) 1986-10-21
NZ188974A (en) 1989-10-27
IT7830171A0 (it) 1978-11-24
AT372384B (de) 1983-09-26
SG61182G (en) 1985-02-15
DE2851028C2 (it) 1990-05-03
MY8500029A (en) 1985-12-31
NO151288B (no) 1984-12-03
DE2851028A1 (de) 1979-05-31
SE435622B (sv) 1984-10-08
AR218514A1 (es) 1980-06-13
IT1160263B (it) 1987-03-11
LU80576A1 (fr) 1979-03-22
CA1100959A (en) 1981-05-12
FI64372C (fi) 1983-11-10
ES475328A1 (es) 1979-04-01
SE7906287L (sv) 1979-07-23
FR2409755A1 (fr) 1979-06-22
FI64372B (fi) 1983-07-29
IN151146B (it) 1983-02-26
FR2423492B1 (it) 1980-12-05
SE8007845L (sv) 1980-11-07
BE872134A (fr) 1979-03-16
NO783958L (no) 1979-05-28

Similar Documents

Publication Publication Date Title
CA1188300A (en) PHARMACOLOGICALLY ACTIVE 3-SUBSTITUTED .beta. CARBOLINES
SU578002A3 (ru) Способ получени производных бензо(в)тиофена или их солей
SE431650B (sv) Indolo (2,3-a) kinolizidiner och sett att framstella dessa
GB1594079A (en) 1-acyl-2-cyanoaziridines
SE449862B (sv) Substituerade, heterocykliska bensamider, sett att framstella dessa och en faramakologisk komposition
SE452610B (sv) Sett att spalta racemiska cis-1,2-cyklopropandikarboxylsyraderivat
US3966760A (en) 2-Substituted-5,6-dimethoxyindazoles
KR100254085B1 (ko) 이미다졸릴 메틸-피리딘류 화합물
GB2086379A (en) Ethylenediamine derivatives
EP0368652B1 (en) Imidazoquinoxalines and their preparation
Seyferth et al. Halomethyl-metal compounds. 71. Application of phenyl (trihalomethyl) mercurials in the preparation of heterocyclic compounds
JPS58164577A (ja) 4―ベンジル―1―(2h)イソキノロン誘導体
FR2496666A1 (fr) Nouveaux derives de cephalosporine et composition pharmaceutique les contenant
Duncan Jr et al. Synthesis of Indolo and benzimidazoquinazolines and benzodiazepines
Kim Synthesis of 1, 2, 3, 4, 8, 9, 10, 11‐octahydro‐[1, 4] diazepino [6, 5, 4‐jk] earbazole and related compounds
US4353911A (en) Indolo(2,3-a)quinolizidines, useful in increasing femoral and vertebral blood flow
FI71738C (fi) Foerfarande foer framstaellning av 5,6,7, 7a-tetrahydro-4h-tien(3,2-c)pyridin-2-onderivat.
Ryczek Synthesis of 3‐Ω‐amino‐2‐thiohydantoins
US5663365A (en) Process for the preparation of pyrazolones
SE450120B (sv) Nya dimetoxikinazolinderivat till anvendning for framstellning av 2(4-substituerade piperazin-1-yl)-4-amino-6,7-dimetoxikinazoliner
US3960926A (en) Process for preparing azasulfonium halide salts
US4062891A (en) N-formyl-2,3,5,6-dibenzobicyclo[5.1.0]octan-4-methylamine
US4564677A (en) Preparation of N-amino compounds
FI86422B (fi) Foerfarande foer framstaellning av n-/(2 -imidazolin-2-yl)metyl/-2-hydroxi-4-amino-5-halogenbensamider, vilka aer anvaendbara saosom gastromotoriska laekemedel.
CA1234113A (en) Aminoalkyl-imidazothiadiazole-alkenecarboxylic acid amides, new intermediates for their preparation, their preparation and their use in medicaments

Legal Events

Date Code Title Description
NUG Patent has lapsed

Ref document number: 7906287-3

Effective date: 19920604

Format of ref document f/p: F