FR2911141B1 - Nouveaux derives triazabenzo[a]naphtho[2,1,8-cde]azulene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. - Google Patents

Nouveaux derives triazabenzo[a]naphtho[2,1,8-cde]azulene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Info

Publication number
FR2911141B1
FR2911141B1 FR0700046A FR0700046A FR2911141B1 FR 2911141 B1 FR2911141 B1 FR 2911141B1 FR 0700046 A FR0700046 A FR 0700046A FR 0700046 A FR0700046 A FR 0700046A FR 2911141 B1 FR2911141 B1 FR 2911141B1
Authority
FR
France
Prior art keywords
triazabenzo
cde
naphtho
novel
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0700046A
Other languages
English (en)
Other versions
FR2911141A1 (fr
Inventor
Jean Daniel Brion
Maud Hervet
Anne Moreau
Zafiarisoa Dolor Renko
Ridant Alain Le
Catherine Harpey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Centre National de la Recherche Scientifique CNRS
Laboratoires Servier SAS
Universite Paris Sud Paris 11
Original Assignee
Centre National de la Recherche Scientifique CNRS
Laboratoires Servier SAS
Universite Paris Sud Paris 11
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0700046A priority Critical patent/FR2911141B1/fr
Application filed by Centre National de la Recherche Scientifique CNRS, Laboratoires Servier SAS, Universite Paris Sud Paris 11 filed Critical Centre National de la Recherche Scientifique CNRS
Priority to US12/448,627 priority patent/US20100105666A1/en
Priority to PCT/FR2008/000012 priority patent/WO2008099081A2/fr
Priority to KR1020097016386A priority patent/KR20090096749A/ko
Priority to CA002674083A priority patent/CA2674083A1/fr
Priority to MX2009007199A priority patent/MX2009007199A/es
Priority to CNA2008800017772A priority patent/CN101611034A/zh
Priority to JP2009544432A priority patent/JP2010514825A/ja
Priority to EP08761736A priority patent/EP2102209A2/fr
Priority to BRPI0806290-0A priority patent/BRPI0806290A2/pt
Priority to EA200900922A priority patent/EA200900922A1/ru
Priority to AU2008214548A priority patent/AU2008214548A1/en
Priority to ARP080100029A priority patent/AR064747A1/es
Publication of FR2911141A1 publication Critical patent/FR2911141A1/fr
Application granted granted Critical
Publication of FR2911141B1 publication Critical patent/FR2911141B1/fr
Priority to MA32051A priority patent/MA31144B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR0700046A 2007-01-05 2007-01-05 Nouveaux derives triazabenzo[a]naphtho[2,1,8-cde]azulene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. Expired - Fee Related FR2911141B1 (fr)

Priority Applications (14)

Application Number Priority Date Filing Date Title
FR0700046A FR2911141B1 (fr) 2007-01-05 2007-01-05 Nouveaux derives triazabenzo[a]naphtho[2,1,8-cde]azulene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
EA200900922A EA200900922A1 (ru) 2007-01-05 2008-01-04 НОВЫЕ СОЕДИНЕНИЯ ТРИАЗАБЕНЗО[α]НАФТО[2,1,8-cde]АЗУЛЕНА, СПОСОБ ИХ ПОЛУЧЕНИЯ И СОДЕРЖАЩИЕ ИХ ФАРМАЦЕВТИЧЕСКИЕ КОМПОЗИЦИИ
KR1020097016386A KR20090096749A (ko) 2007-01-05 2008-01-04 트리아자벤조〔ａ〕나프토〔２，１，８­ｃｄｅ〕아줄렌 유도체, 이의 제조방법 및 이를 함유하는 약제 조성물
CA002674083A CA2674083A1 (fr) 2007-01-05 2008-01-04 Nouveaux derives triazabenzo[.alpha.]naphtho[2,1,8-cde]azulene, leur procede de preparation et les compositions pharmaceutiques qui les contien nent
MX2009007199A MX2009007199A (es) 2007-01-05 2008-01-04 Compuestos de triazabenzo[a]nafto[2,1,8-cde]azuleno novedosos, metodo para preparar los mismos y composiciones farmaceuticas que contienen los mismos.
CNA2008800017772A CN101611034A (zh) 2007-01-05 2008-01-04 新的三氮杂苯并[a]萘并[2,1,8-cde]薁衍生物、它们的制备方法和含有它们的药物组合物
JP2009544432A JP2010514825A (ja) 2007-01-05 2008-01-04 新規トリアザベンゾ［ａ］ナフト［２，１，８−ｃｄｅ］アズレン誘導体、その製造法、及びそれを含有する医薬組成物
EP08761736A EP2102209A2 (fr) 2007-01-05 2008-01-04 Nouveaux dérivés triazabenzo[a]naphtho[2,l,8-cde]azulène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent
US12/448,627 US20100105666A1 (en) 2007-01-05 2008-01-04 Triazabenzo (a)naphtho(2,1,8-cde) azulene compounds.
PCT/FR2008/000012 WO2008099081A2 (fr) 2007-01-05 2008-01-04 NOUVEAUX DÉRIVÉS TRIAZABENZO[α]NAPHTHO[2,L,8-CDE]AZULÈNE, LEUR PROCÉDÉ DE PRÉPARATION ET LES COMPOSITIONS PHARMACEUTIQUES QUI LES CONTIENNENT
AU2008214548A AU2008214548A1 (en) 2007-01-05 2008-01-04 Novel triazabenzo[&Agr;]naphtho[2,L,8-CDE]azulene derivatives, method for preparing the same and pharmaceutical compositions containing the same
ARP080100029A AR064747A1 (es) 2007-01-05 2008-01-04 Derivados de triazabenzo[(alfa)]nafto[2,1,8-cde]azuleno su porcedimiento de preparacion y las composiciones farmaceuticas que los contienen
BRPI0806290-0A BRPI0806290A2 (pt) 2007-01-05 2008-01-04 derivados triabenzo[alfa] nafto[2,l,8-cde] azuleno, o respectivo processo de preparação e as composições farmacêuticas que os contêm
MA32051A MA31144B1 (fr) 2007-01-05 2009-06-29 Nouveaux dérivés triazabenzo[a]naphtho[2,l,8-cde]azulène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0700046A FR2911141B1 (fr) 2007-01-05 2007-01-05 Nouveaux derives triazabenzo[a]naphtho[2,1,8-cde]azulene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Publications (2)

Publication Number Publication Date
FR2911141A1 FR2911141A1 (fr) 2008-07-11
FR2911141B1 true FR2911141B1 (fr) 2009-02-20

Family

ID=38278893

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0700046A Expired - Fee Related FR2911141B1 (fr) 2007-01-05 2007-01-05 Nouveaux derives triazabenzo[a]naphtho[2,1,8-cde]azulene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Country Status (14)

Country Link
US (1) US20100105666A1 (fr)
EP (1) EP2102209A2 (fr)
JP (1) JP2010514825A (fr)
KR (1) KR20090096749A (fr)
CN (1) CN101611034A (fr)
AR (1) AR064747A1 (fr)
AU (1) AU2008214548A1 (fr)
BR (1) BRPI0806290A2 (fr)
CA (1) CA2674083A1 (fr)
EA (1) EA200900922A1 (fr)
FR (1) FR2911141B1 (fr)
MA (1) MA31144B1 (fr)
MX (1) MX2009007199A (fr)
WO (1) WO2008099081A2 (fr)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA786426B (en) * 1977-11-25 1979-10-31 Scras New indulo(2,3-a)quinolizidines,preparation and therapeutic use
FR2713643B1 (fr) * 1993-12-14 1996-06-07 Adir Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
FR2713644B1 (fr) * 1993-12-14 1996-02-09 Adir Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
WO2008099081A3 (fr) 2008-10-23
EA200900922A1 (ru) 2010-02-26
CA2674083A1 (fr) 2008-08-21
BRPI0806290A2 (pt) 2011-09-06
US20100105666A1 (en) 2010-04-29
JP2010514825A (ja) 2010-05-06
AU2008214548A1 (en) 2008-08-21
KR20090096749A (ko) 2009-09-14
MX2009007199A (es) 2009-08-12
AR064747A1 (es) 2009-04-22
WO2008099081A2 (fr) 2008-08-21
CN101611034A (zh) 2009-12-23
MA31144B1 (fr) 2010-02-01
EP2102209A2 (fr) 2009-09-23
FR2911141A1 (fr) 2008-07-11

Similar Documents

Publication Publication Date Title
FR2920773B1 (fr) Derives de 1,2,4,5-tetrahydro-3h-benzazepines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2909379B1 (fr) Nouveaux derives heterocycliques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
MA28342A1 (fr) Nouveaux derives azabicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2903101B1 (fr) Nouveaux derives naphtaleniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2934596B1 (fr) Nouveaux derives de l'oxime de cholest-4-en-3-one, compositions pharmaceutiques les renfermant, et procede de preparation
MA27410A1 (fr) Nouveaux composes pyridopyrimidinone leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2903404B1 (fr) Nouveaux derives tetracycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2912145B1 (fr) Nouveaux derives tricycliques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2883876B1 (fr) Derives d'indanyl-piperazines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2885616B1 (fr) Nouveaux derives de phenylpyridinylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2881138B1 (fr) Nouveaux derives d'oximes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2872164B1 (fr) Derives de quinoleines-4-substituees, leur procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
FR2907451B1 (fr) "nouveaux derives indoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent"
FR2885615B1 (fr) Nouveaux derives de phenylpyridinylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2896800B1 (fr) Nouveaux composes pyridinylaminoalkylene-et pyridinyloxyalkylene-cyclopropanamines polysubstitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2916757B1 (fr) Nouveaux derives diazeniumdiolates,leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2884251B1 (fr) Derives de piperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2877338B1 (fr) Nouveaux derives de benzothiadiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
MA29223B1 (fr) Nouveaux derives naphtaleniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2907452B1 (fr) "nouveaux derives indoliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent"
FR2933983B1 (fr) Nouveaux derives tricycliques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2918370B1 (fr) Nouveaux derives naphtaleniques,leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2911141B1 (fr) Nouveaux derives triazabenzo[a]naphtho[2,1,8-cde]azulene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2889187B1 (fr) Nouveaux composes 1,1-pyridinyloxycyclopropanamines polysusbstitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2856064B1 (fr) Nouveaux derives de benzothiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.

Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20110930