SE408642B - Analogiforfarande for framstellning av n-tienylmettlderivat av morfinaner och bensomorfaner - Google Patents

Analogiforfarande for framstellning av n-tienylmettlderivat av morfinaner och bensomorfaner

Info

Publication number
SE408642B
SE408642B SE7305148A SE7305148A SE408642B SE 408642 B SE408642 B SE 408642B SE 7305148 A SE7305148 A SE 7305148A SE 7305148 A SE7305148 A SE 7305148A SE 408642 B SE408642 B SE 408642B
Authority
SE
Sweden
Prior art keywords
formula
compound
acid
hydroxy
thienylmethyl
Prior art date
Application number
SE7305148A
Other languages
English (en)
Swedish (sv)
Inventor
H Merz
A Langbein
K Stockhaus
H Wick
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of SE408642B publication Critical patent/SE408642B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/22—Bridged ring systems
    • C07D221/26—Benzomorphans

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE7305148A 1972-04-12 1973-04-11 Analogiforfarande for framstellning av n-tienylmettlderivat av morfinaner och bensomorfaner SE408642B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2217420A DE2217420C3 (de) 1972-04-12 1972-04-12 N-Thienylmethyl-Heterocyclen, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Zubereitungen

Publications (1)

Publication Number Publication Date
SE408642B true SE408642B (sv) 1979-06-25

Family

ID=5841625

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7305148A SE408642B (sv) 1972-04-12 1973-04-11 Analogiforfarande for framstellning av n-tienylmettlderivat av morfinaner och bensomorfaner

Country Status (7)

Country Link
US (1) US3917606A (de)
DE (1) DE2217420C3 (de)
DK (1) DK133555C (de)
FI (1) FI57409C (de)
GB (1) GB1425347A (de)
NO (1) NO137695C (de)
SE (1) SE408642B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2437610A1 (de) * 1974-08-05 1976-02-26 Boehringer Sohn Ingelheim Neue 5,9-beta-disubstituierte 2-tetrahydrofurfuryl-6,7-benzomorphane, deren saeureadditionssalze, ihre verwendung als arzneimittel und verfahren zu deren herstellung
GB1575009A (en) * 1976-06-21 1980-09-17 Acf Chemiefarma Nv 6,7-benzomorphan derivatives
CN1111900A (zh) * 1993-06-30 1995-11-15 东丽株式会社 止咳药
CA2143864C (en) * 1993-07-23 2006-01-24 Hiroshi Nagase Morphinan derivatives and pharmaceutical use thereof
US6844438B2 (en) * 2001-08-15 2005-01-18 Mclean Hospital Corporation N-substituted derivatives of morphinan and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE582575A (de) * 1958-09-22
US3647806A (en) * 1966-04-18 1972-03-07 Syntex Corp Tetrahydropyranyl and tetrahydro-furanyl benzomorphan ethers

Also Published As

Publication number Publication date
NO137695B (no) 1977-12-27
DE2217420A1 (de) 1973-10-31
GB1425347A (en) 1976-02-18
DE2217420B2 (de) 1980-08-07
NO137695C (no) 1978-04-05
DE2217420C3 (de) 1981-03-12
DK133555B (da) 1976-06-08
FI57409B (fi) 1980-04-30
DK133555C (da) 1976-10-25
FI57409C (fi) 1980-08-11
US3917606A (en) 1975-11-04

Similar Documents

Publication Publication Date Title
Rinehart Jr et al. Eudistomins AQ,. beta.-carbolines from the antiviral Caribbean tunicate Eudistoma olivaceum
FI63229C (fi) Foerfarande foer framstaellning av analgetiskt verkande racemiskt eller diastereomera och optiskt aktiva 2-tetrahydrofurfuryl-5,9 beta-dimetyl-6,7-bensomorfaner och deras syraadditionssalter
EP1590338B1 (de) Melanocortin-rezeptormodulatoren
FI61696B (fi) Foerfarande foer framstaellning av vasodilatoriska 1,4-dihydropyridinderivat
CA1049511A (en) 2-tetrahydrofurfuryl-6,7-benzomorphanes, their acid addition salts, their use as pharmaceuticals and processes for their production
SE465163B (sv) Imidazokinolinyleterderivat, foerfarande foer framstaellning av detta och en farmaceutisk beredning
EP1797040A1 (de) Muscarin-rezeptor-antagonisten
HU176479B (en) Process for preparing new n-/methoxymethyl-furyl-methyl/-6,7-benzomorphans and -morphians further acid addition snlts thereof
JP2674199B2 (ja) 二環式アミン化合物およびその製造法
EP1427417B1 (de) 3-substituierte 6,7-dihydroxytetrahydroisochinolin-derivate zur verwendung als antibkaterielle mittel
NL193541C (nl) 8 Alfa-acylaminoergolinen, werkwijzen voor de bereiding daarvan en preparaten die ze bevatten.
FR2537584A1 (fr) Pyrazoloquinoleines substituees particulieres, procede pour leur preparation, preparations pharmaceutiques contenant ces composes et leur application therapeutique
SE408642B (sv) Analogiforfarande for framstellning av n-tienylmettlderivat av morfinaner och bensomorfaner
JPH1095766A (ja) アセトアミド誘導体、及びその用途
Aubry et al. Racemic and diastereoselective synthesis of aryl and heteroaryl tetrahydroisoquinolines via the pictet‐spengler reaction
HU224435B1 (hu) Benzodiazepin-származékok, eljárás előállításukra, alkalmazásukra és ezeket tartalmazó gyógyászati készítmények
WO2002042309A1 (fr) Dérivés d'indole et leur utilisation dans des médicaments
EP1630159A1 (de) 5-HT7 Rezeptorenantagonisten
JPH06247935A (ja) ６，７−ジアルコキシ−３，４−ジヒドロイソキノリン−８−オール類、その製造法及び該化合物を用いた６，７−ジアルコキシ−１，２，３，４−テトラヒドロイソキノリン−８−オール類の製造法
JPS61176589A (ja) インドール‐３‐イル‐キナゾリノ‐１，４‐ベンゾジアゼピン‐５，１３‐ジオン
DK141629B (da) Analogifremgangsmaade til fremstilling af 7alfasubstituerede n-(furylmethyl)-6,14-endoetheno-eller-6,14-endoethano-tetrahydronororipaviner eller syreadditionssalte deraf
GB1559979A (en) N-substituted - 6,8 - dioxamorphinans and process for their preparation
SU1331431A3 (ru) Способ получени (1,2)-анеллированных 1,4-бензодиазепинов или их оптических изомеров или кислотно-аддитивных солей
NZ233058A (en) 2,8-disubstituted dibenzofuran derivatives and pharmaceutical compositions
SE457260B (sv) Mellanprodukt foer framstaellning av 2-metyl-ergopeptiner och saett att framstaella mellanprodukten