SE0202133D0 - Novel compounds - Google Patents

Novel compounds

Info

Publication number
SE0202133D0
SE0202133D0 SE0202133A SE0202133A SE0202133D0 SE 0202133 D0 SE0202133 D0 SE 0202133D0 SE 0202133 A SE0202133 A SE 0202133A SE 0202133 A SE0202133 A SE 0202133A SE 0202133 D0 SE0202133 D0 SE 0202133D0
Authority
SE
Sweden
Prior art keywords
novel compounds
therapy
processes
formula
preparation
Prior art date
Application number
SE0202133A
Other languages
English (en)
Swedish (sv)
Inventor
Nafizal Hossain
Marguerite Mensonides-Harsema
Svetlana Ivanova
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Priority to SE0202133A priority Critical patent/SE0202133D0/xx
Publication of SE0202133D0 publication Critical patent/SE0202133D0/xx
Priority to TW092118200A priority patent/TW200413386A/zh
Priority to SI200331163T priority patent/SI1521757T1/sl
Priority to NZ537259A priority patent/NZ537259A/en
Priority to AT03762957T priority patent/ATE385235T1/de
Priority to CA002492122A priority patent/CA2492122A1/en
Priority to AU2003243122A priority patent/AU2003243122B2/en
Priority to US10/520,699 priority patent/US7449475B2/en
Priority to JP2004519472A priority patent/JP2005537255A/ja
Priority to RU2004137278/04A priority patent/RU2320664C2/ru
Priority to DK03762957T priority patent/DK1521757T3/da
Priority to DE60318948T priority patent/DE60318948T2/de
Priority to PL03374877A priority patent/PL374877A1/xx
Priority to PCT/SE2003/001185 priority patent/WO2004005295A1/en
Priority to CNB038191466A priority patent/CN1326858C/zh
Priority to CNA2006101435561A priority patent/CN1974574A/zh
Priority to PT03762957T priority patent/PT1521757E/pt
Priority to UA20041210166A priority patent/UA77809C2/uk
Priority to ES03762957T priority patent/ES2298575T3/es
Priority to BR0312560-2A priority patent/BR0312560A/pt
Priority to EP03762957A priority patent/EP1521757B1/en
Priority to MXPA05000278A priority patent/MXPA05000278A/es
Priority to AR20030102463A priority patent/AR040475A1/es
Priority to ZA200500024A priority patent/ZA200500024B/xx
Priority to IS7662A priority patent/IS7662A/is
Priority to NO20050635A priority patent/NO20050635L/no
Priority to HK05106846A priority patent/HK1074622A1/xx
Priority to CY20081100375T priority patent/CY1107915T1/el
Priority to US12/265,251 priority patent/US20090062322A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20Spiro-condensed ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10Spiro-condensed systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
SE0202133A 2002-07-08 2002-07-08 Novel compounds SE0202133D0 (sv)

Priority Applications (29)

Application Number Priority Date Filing Date Title
SE0202133A SE0202133D0 (sv) 2002-07-08 2002-07-08 Novel compounds
TW092118200A TW200413386A (en) 2002-07-08 2003-07-03 Novel compounds
MXPA05000278A MXPA05000278A (es) 2002-07-08 2003-07-07 Nuevas espiropiperidinas o espiropirrolidinas triciclicas.
PL03374877A PL374877A1 (en) 2002-07-08 2003-07-07 Novel tricyclic spiropiperidines or spiropyrrolidines
CNA2006101435561A CN1974574A (zh) 2002-07-08 2003-07-07 新的三环螺吡咯烷
AT03762957T ATE385235T1 (de) 2002-07-08 2003-07-07 Tricyclische spiropiperidine oder spiropyrrolidine
CA002492122A CA2492122A1 (en) 2002-07-08 2003-07-07 Novel tricyclic spiropiperidines or spiropyrrolidines
AU2003243122A AU2003243122B2 (en) 2002-07-08 2003-07-07 Novel tricyclic spiropiperidines or spiropyrrolidines
US10/520,699 US7449475B2 (en) 2002-07-08 2003-07-07 Tricyclic spiropiperidines or spiropyrrolidines
JP2004519472A JP2005537255A (ja) 2002-07-08 2003-07-07 新規三環式スピロピペリジンまたはスピロピロリジン
RU2004137278/04A RU2320664C2 (ru) 2002-07-08 2003-07-07 Новые трициклические спиропиперидины или спиропирролидины
DK03762957T DK1521757T3 (da) 2002-07-08 2003-07-07 Tricykliske spiropiperidiner eller spiropyrrolidiner
DE60318948T DE60318948T2 (de) 2002-07-08 2003-07-07 Tricyclische spiropiperidine oder spiropyrrolidine
SI200331163T SI1521757T1 (sl) 2002-07-08 2003-07-07 Triciklični spiropiperidini ali spiropirolidini
PCT/SE2003/001185 WO2004005295A1 (en) 2002-07-08 2003-07-07 Novel tricyclic spiropiperidines or spiropyrrolidines
CNB038191466A CN1326858C (zh) 2002-07-08 2003-07-07 三环螺哌啶化合物
NZ537259A NZ537259A (en) 2002-07-08 2003-07-07 Novel tricyclic spiropiperidines or spiropyrrolidines
PT03762957T PT1521757E (pt) 2002-07-08 2003-07-07 Espiropiperidinas ou espiropirrolidinas tricíclicas
UA20041210166A UA77809C2 (en) 2002-07-08 2003-07-07 Tricyclic spiropiperidines or spiropyrrolidines, method for their synthesis (variants), use thereof, method for treating inflammations and respiratory diseases, pharmaceutical composition, intermediate, method for producing intermediate
ES03762957T ES2298575T3 (es) 2002-07-08 2003-07-07 Nuevas espiropiperidinas o espiropirrolidinas triciclicas.
BR0312560-2A BR0312560A (pt) 2002-07-08 2003-07-07 Novas espiropiperidinas ou espiropirrolidinas tricìclicas
EP03762957A EP1521757B1 (en) 2002-07-08 2003-07-07 tricyclic spiropiperidines or spiropyrrolidines
AR20030102463A AR040475A1 (es) 2002-07-08 2003-07-08 Espiropiperidinas o espiropirrolidinas triciclicas
ZA200500024A ZA200500024B (en) 2002-07-08 2005-01-03 Novel tricyclic spiropiperidines or spiropyrrolidines.
IS7662A IS7662A (is) 2002-07-08 2005-01-24 Ný þríhringlaga spírópíperídín eða spírópýrrólídín
NO20050635A NO20050635L (no) 2002-07-08 2005-02-04 Nye tricykliske spiropiperidiner eller spiropyrrolidiner
HK05106846A HK1074622A1 (en) 2002-07-08 2005-08-09 Tricyclic spiropiperidines or spiropyrolidines
CY20081100375T CY1107915T1 (el) 2002-07-08 2008-04-03 Τρικυκλικες σπιροπιπεριδινες ή σπιροπυρρολιδινες
US12/265,251 US20090062322A1 (en) 2002-07-08 2008-11-05 Novel Tricyclic Spiropiperidines or Spiropyrrolidines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0202133A SE0202133D0 (sv) 2002-07-08 2002-07-08 Novel compounds

Publications (1)

Publication Number Publication Date
SE0202133D0 true SE0202133D0 (sv) 2002-07-08

Family

ID=20288470

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0202133A SE0202133D0 (sv) 2002-07-08 2002-07-08 Novel compounds

Country Status (26)

Country Link
US (2) US7449475B2 (no)
EP (1) EP1521757B1 (no)
JP (1) JP2005537255A (no)
CN (2) CN1326858C (no)
AR (1) AR040475A1 (no)
AT (1) ATE385235T1 (no)
AU (1) AU2003243122B2 (no)
BR (1) BR0312560A (no)
CA (1) CA2492122A1 (no)
CY (1) CY1107915T1 (no)
DE (1) DE60318948T2 (no)
DK (1) DK1521757T3 (no)
ES (1) ES2298575T3 (no)
HK (1) HK1074622A1 (no)
IS (1) IS7662A (no)
MX (1) MXPA05000278A (no)
NO (1) NO20050635L (no)
NZ (1) NZ537259A (no)
PL (1) PL374877A1 (no)
PT (1) PT1521757E (no)
RU (1) RU2320664C2 (no)
SE (1) SE0202133D0 (no)
TW (1) TW200413386A (no)
UA (1) UA77809C2 (no)
WO (1) WO2004005295A1 (no)
ZA (1) ZA200500024B (no)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE0202133D0 (sv) 2002-07-08 2002-07-08 Astrazeneca Ab Novel compounds
US7732442B2 (en) 2003-09-05 2010-06-08 Ono Pharmaceutical Co., Ltd. Chemokine receptor antagonist and medical use thereof
SE0302755D0 (sv) * 2003-10-17 2003-10-17 Astrazeneca Ab Novel compounds
US20070021498A1 (en) * 2004-10-14 2007-01-25 Nafizal Hossain Novel tricyclic spiroderivatives as modulators of chemokine receptor activity
SE0302811D0 (sv) * 2003-10-23 2003-10-23 Astrazeneca Ab Novel compounds
SE0303090D0 (sv) 2003-11-20 2003-11-20 Astrazeneca Ab Novel compounds
SE0303280D0 (sv) * 2003-12-05 2003-12-05 Astrazeneca Ab Novel compounds
SE0303541D0 (sv) 2003-12-22 2003-12-22 Astrazeneca Ab New compounds
TWI350168B (en) 2004-05-07 2011-10-11 Incyte Corp Amido compounds and their use as pharmaceuticals
NZ551603A (en) 2004-06-24 2010-11-26 Incyte Corp N-substituted piperidines and their use as pharmaceuticals
WO2006109085A1 (en) 2005-04-13 2006-10-19 Astex Therapeutics Limited Hydroxybenzamide derivatives and their use as inhibitors of hsp90
WO2007028638A1 (en) 2005-09-09 2007-03-15 Euro-Celtique S.A. Fused and spirocycle compounds and the use thereof
JP5315590B2 (ja) * 2006-02-14 2013-10-16 Jnc株式会社 液晶化合物、液晶組成物および液晶表示素子
US7754725B2 (en) 2006-03-01 2010-07-13 Astex Therapeutics Ltd. Dihydroxyphenyl isoindolymethanones
AU2007275931B2 (en) 2006-07-19 2011-06-16 Astrazeneca Ab Novel tricyclic spiropiperidine compounds, their synthesis and their uses as modulators of chemokine receptor activity
WO2008044054A2 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Hydroxy-substituted benzoic acid amide compounds for use in therapy
JP5528806B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
GB0620259D0 (en) 2006-10-12 2006-11-22 Astex Therapeutics Ltd Pharmaceutical compounds
JP5721949B2 (ja) 2006-10-12 2015-05-20 アステックス、セラピューティックス、リミテッドAstex Therapeutics Limited 複合薬剤
WO2008044045A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
US8779132B2 (en) 2006-10-12 2014-07-15 Astex Therapeutics Limited Pharmaceutical compounds
WO2008083124A1 (en) 2006-12-28 2008-07-10 Rigel Pharmaceuticals, Inc. N-substituted-heterocycloalkyloxybenzamide compounds and methods of use
EP2125728A4 (en) * 2007-02-23 2011-06-22 Astrazeneca Ab NOVEL COMBINATION OF COMPOUNDS FOR THE TREATMENT OF AIRWAY DISEASES, IN PARTICULAR CHRONIC OBSTRUCTIVE BRONCHOPNEUMOPATHY (COPD) AND ASTHMA
WO2008103126A1 (en) * 2007-02-23 2008-08-28 Astrazeneca Ab Novel combination of compounds to be used in the treatment of airway diseases, especially chronic obstructive pulmonary disease (copd) and asthma
WO2008121066A1 (en) * 2007-03-30 2008-10-09 Astrazeneca Ab Novel tricyclic spiropiperidines or spiropyrrolidines and their use as modulators of chemokine receptors
UY31162A1 (es) * 2007-06-20 2008-11-28 Glaxo Group Ltd Espiroindolinas como moduladores de receptores de quimioquinas
WO2009011655A1 (en) * 2007-07-17 2009-01-22 Astrazeneca Ab Splropiperidine compounds, a process of their preparation, pharmaceutical compositions containing them, and their use in the treatment of airway diseases, inflammatory diseases, copd or asthma
WO2009011653A1 (en) * 2007-07-17 2009-01-22 Astrazeneca Ab A process for the preparation of intermediates and their us in the synthesis of spiropiperidine compounds
EP2173714B9 (en) * 2007-07-24 2013-04-10 Bristol-Myers Squibb Company Piperidine derivatives as modulators of chemokine receptor activity
US20110124671A1 (en) * 2007-08-14 2011-05-26 Budzik Brian W Spiroindenes and spiroindanes as modulators of chemokine receptors
WO2009061881A1 (en) * 2007-11-07 2009-05-14 Glaxo Group Limited Spirodihydrobenzofurans as modulators of chemokine receptors
ES2390004T3 (es) 2008-01-30 2012-11-05 Cephalon, Inc. Derivados sustituidos de piperidina espirocíclica como ligandos del receptor de la histamina 3(H3)
FR2928150A1 (fr) 2008-02-29 2009-09-04 Vetoquinol Sa Sa Nouveaux derives 7-substitues de 3-carboxy-oxadiazino-quinolones, leur preparation et leur application comme anti-bacteriens
GB0806527D0 (en) 2008-04-11 2008-05-14 Astex Therapeutics Ltd Pharmaceutical compounds
EP2145891A1 (en) 2008-07-09 2010-01-20 Vetoquinol S.A. 9-substituted-5-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials
AR078948A1 (es) * 2009-11-30 2011-12-14 Lilly Co Eli Compuestos de espiropiperidina, composicion farmaceutica que lo comprenden y su uso para preparar un medicamento util para tratar la diabetes
US10752588B2 (en) 2014-12-19 2020-08-25 The Broad Institute, Inc. Dopamine D2 receptor ligands
WO2016100940A1 (en) 2014-12-19 2016-06-23 The Broad Institute, Inc. Dopamine d2 receptor ligands
EP3668840A1 (en) 2017-08-15 2020-06-24 Inflazome Limited Novel sulfonamide carboxamide compounds

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4010201A (en) * 1974-04-12 1977-03-01 The Upjohn Company Organic compounds
US4166120A (en) * 1978-04-14 1979-08-28 American Hoechst Corporation Analgesic and tranquilizing benzoylpropyl-spiro[dihydrobenzofuran]piperidines and pyrrolidines
US4166119A (en) 1978-04-14 1979-08-28 American Hoechst Corporation Analgesic and tranquilizing spiro[dihydrobenzofuran]piperidines and pyrrolidines
US4263317A (en) * 1979-09-06 1981-04-21 Hoechst-Roussel Pharmaceuticals, Inc. Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s
US5366986A (en) 1988-04-15 1994-11-22 T Cell Sciences, Inc. Compounds which inhibit complement and/or suppress immune activity
DE3930262A1 (de) 1989-09-11 1991-03-21 Thomae Gmbh Dr K Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
WO1994013696A1 (en) * 1992-12-11 1994-06-23 Merck & Co., Inc. Spiro piperidines and homologs which promote release of growth hormone
EP0681571B1 (en) * 1993-01-28 1998-07-29 Merck & Co. Inc. Spiro-substituted azacycles as tachykinin receptor antagonists
JPH09512016A (ja) * 1994-04-14 1997-12-02 メルク エンド カンパニー インコーポレーテッド α1Cアドレナリン受容体拮抗薬
US5576321A (en) 1995-01-17 1996-11-19 Eli Lilly And Company Compounds having effects on serotonin-related systems
DE59610077D1 (de) 1995-05-18 2003-02-27 Altana Pharma Ag Phenyldihydrobenzofurane
US5931917A (en) * 1996-09-26 1999-08-03 Verifone, Inc. System, method and article of manufacture for a gateway system architecture with system administration information accessible from a browser
AU5803398A (en) * 1996-12-13 1998-07-03 Merck & Co., Inc. Spiro-substituted azacycles as modulators of chemokine receptor activity
US5962462A (en) * 1996-12-13 1999-10-05 Merck & Co., Inc. Spiro-substituted azacycles as modulators of chemokine receptor activity
CA2278309A1 (en) * 1997-01-21 1998-07-23 Merck & Co., Inc. 3,3-disubstituted piperidines as modulators of chemokine receptor activity
YU41100A (sh) 1998-02-04 2002-06-19 Banyu Pharmaceutical Co. Ltd. N-acil derivati cikličnih amina
US6151675A (en) * 1998-07-23 2000-11-21 Tumbleweed Software Corporation Method and apparatus for effecting secure document format conversion
US6288083B1 (en) 1998-09-04 2001-09-11 Millennium Pharmaceuticals, Inc. Chemokine receptor antagonists and methods of use therefor
US6212640B1 (en) * 1999-03-25 2001-04-03 Sun Microsystems, Inc. Resources sharing on the internet via the HTTP
US6226752B1 (en) * 1999-05-11 2001-05-01 Sun Microsystems, Inc. Method and apparatus for authenticating users
AU1244001A (en) 1999-10-27 2001-05-08 Cor Therapeutics, Inc. Pyridyl-containing spirocyclic compounds as inhibitors of fibrinogen-dependent platelet aggregation
AU2001243394A1 (en) * 2000-03-02 2001-09-12 Smith Kline Beecham Corporation Compounds and methods
AR028948A1 (es) 2000-06-20 2003-05-28 Astrazeneca Ab Compuestos novedosos
US7017175B2 (en) * 2001-02-02 2006-03-21 Opentv, Inc. Digital television application protocol for interactive television
WO2002102387A1 (en) 2001-06-18 2002-12-27 H. Lundbeck A/S Treatment of neuropathic pain
US20050143372A1 (en) 2001-10-30 2005-06-30 Shomir Ghosh Compounds, pharmaceutical compositions and methods of use therefor
SE0202133D0 (sv) 2002-07-08 2002-07-08 Astrazeneca Ab Novel compounds
AU2003284984B2 (en) 2002-10-30 2008-10-23 Merck Sharp & Dohme Corp. Gamma-aminoamide modulators of chemokine receptor activity
WO2004050024A2 (en) * 2002-11-27 2004-06-17 Incyte Corporation 3-aminopyrrolidine derivatives as modulators of chemokine receptors
WO2004051453A1 (en) * 2002-12-04 2004-06-17 Entriq Inc. Multiple content provider user interface
US7966418B2 (en) * 2003-02-21 2011-06-21 Axeda Corporation Establishing a virtual tunnel between two computer programs
SE0302755D0 (sv) * 2003-10-17 2003-10-17 Astrazeneca Ab Novel compounds
US20070021498A1 (en) * 2004-10-14 2007-01-25 Nafizal Hossain Novel tricyclic spiroderivatives as modulators of chemokine receptor activity
SE0302811D0 (sv) 2003-10-23 2003-10-23 Astrazeneca Ab Novel compounds
SE0303090D0 (sv) 2003-11-20 2003-11-20 Astrazeneca Ab Novel compounds
SE0303280D0 (sv) 2003-12-05 2003-12-05 Astrazeneca Ab Novel compounds
SE0303541D0 (sv) 2003-12-22 2003-12-22 Astrazeneca Ab New compounds
MXPA06011265A (es) 2004-03-29 2006-12-15 Pfizer Compuestos propanamida alfa aril o heteroaril metil beta piperidino como antagonistas del receptor orl1.

Also Published As

Publication number Publication date
CN1326858C (zh) 2007-07-18
DE60318948T2 (de) 2009-05-20
ATE385235T1 (de) 2008-02-15
ES2298575T3 (es) 2008-05-16
NO20050635L (no) 2005-03-31
NZ537259A (en) 2006-08-31
IS7662A (is) 2005-01-24
HK1074622A1 (en) 2005-11-18
EP1521757A1 (en) 2005-04-13
PT1521757E (pt) 2008-04-03
RU2320664C2 (ru) 2008-03-27
TW200413386A (en) 2004-08-01
US20050245741A1 (en) 2005-11-03
US7449475B2 (en) 2008-11-11
PL374877A1 (en) 2005-11-14
BR0312560A (pt) 2005-05-10
DE60318948D1 (de) 2008-03-20
CA2492122A1 (en) 2004-01-15
AU2003243122B2 (en) 2006-09-28
US20090062322A1 (en) 2009-03-05
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AU2003243122A1 (en) 2004-01-23
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AR040475A1 (es) 2005-04-06
RU2004137278A (ru) 2005-09-10
JP2005537255A (ja) 2005-12-08
DK1521757T3 (da) 2008-05-05
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WO2004005295A1 (en) 2004-01-15

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