ATE332301T1 - Antivirale pyrazolopyridin verbindungen - Google Patents

Antivirale pyrazolopyridin verbindungen

Info

Publication number
ATE332301T1
ATE332301T1 AT02723554T AT02723554T ATE332301T1 AT E332301 T1 ATE332301 T1 AT E332301T1 AT 02723554 T AT02723554 T AT 02723554T AT 02723554 T AT02723554 T AT 02723554T AT E332301 T1 ATE332301 T1 AT E332301T1
Authority
AT
Austria
Prior art keywords
antiviral
pyrazolopyridine compounds
compounds
pyrazolopyridine
same
Prior art date
Application number
AT02723554T
Other languages
English (en)
Inventor
Mui Cheung
Kristjan Gudmundsson
Brian A Johns
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of ATE332301T1 publication Critical patent/ATE332301T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT02723554T 2001-04-10 2002-03-21 Antivirale pyrazolopyridin verbindungen ATE332301T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28274901P 2001-04-10 2001-04-10

Publications (1)

Publication Number Publication Date
ATE332301T1 true ATE332301T1 (de) 2006-07-15

Family

ID=23082954

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02723554T ATE332301T1 (de) 2001-04-10 2002-03-21 Antivirale pyrazolopyridin verbindungen

Country Status (7)

Country Link
US (2) US7141569B2 (de)
EP (1) EP1377575B1 (de)
JP (1) JP4219171B2 (de)
AT (1) ATE332301T1 (de)
DE (1) DE60212949T2 (de)
ES (1) ES2266487T3 (de)
WO (1) WO2002083672A1 (de)

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US7807673B2 (en) * 2005-12-05 2010-10-05 Glaxosmithkline Llc 2-pyrimidinyl pyrazolopyridine ErbB kinase inhibitors
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EP2402336A1 (de) 2010-06-29 2012-01-04 Basf Se Pyrazolopyridin-Verbindungen
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US20170107216A1 (en) 2015-10-19 2017-04-20 Incyte Corporation Heterocyclic compounds as immunomodulators
AU2016358100B2 (en) 2015-11-19 2021-05-27 Incyte Corporation Heterocyclic compounds as immunomodulators
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TWI850624B (zh) 2015-12-22 2024-08-01 美商英塞特公司 作為免疫調節劑之雜環化合物
CN108779490A (zh) * 2016-01-08 2018-11-09 雅培分子公司 包含硫氰酸胍的杂交缓冲液
TW201808950A (zh) 2016-05-06 2018-03-16 英塞特公司 作為免疫調節劑之雜環化合物
US20170342060A1 (en) 2016-05-26 2017-11-30 Incyte Corporation Heterocyclic compounds as immunomodulators
DK3472167T3 (da) 2016-06-20 2022-09-05 Incyte Corp Heterocykliske forbindelser som immunomodulatorer
EP3484866B1 (de) 2016-07-14 2022-09-07 Incyte Corporation Heterocyclische verbindungen als immunmodulatoren
EP3504198B1 (de) 2016-08-29 2023-01-25 Incyte Corporation Heterocyclische verbindungen als immunmodulatoren
EP3558963B1 (de) 2016-12-22 2022-03-23 Incyte Corporation Bicyclische heteroaromatische verbindungen als immunmodulatoren
ES2874756T3 (es) 2016-12-22 2021-11-05 Incyte Corp Derivados de triazolo[1,5-A]piridina como inmunomoduladores
ES2929193T3 (es) 2016-12-22 2022-11-25 Incyte Corp Derivados de tetrahidro imidazo[4,5-c]piridina como inductores de la internalización de PD-L1
EP3558973B1 (de) 2016-12-22 2021-09-15 Incyte Corporation Pyridinderivate als immunmodulatoren
IL295660A (en) 2016-12-22 2022-10-01 Incyte Corp Benzooxazole derivatives as immunomodulators
RS64055B1 (sr) 2018-03-30 2023-04-28 Incyte Corp Heterociklična jedinjenja kao imunomodulatori
EP4219492B1 (de) 2018-05-11 2024-11-27 Incyte Corporation Heterocyclische verbindungen als immunmodulatoren
JP7665593B2 (ja) 2019-08-09 2025-04-21 インサイト・コーポレイション Ｐｄ－１／ｐｄ－ｌ１阻害剤の塩
EP4037773A1 (de) 2019-09-30 2022-08-10 Incyte Corporation Pyrido[3,2-d]pyrimidin-verbindungen als immunmodulatoren
BR112022009031A2 (pt) 2019-11-11 2022-10-11 Incyte Corp Sais e formas cristalinas de um inibidor de pd-1/pd-l1
EP4240739A1 (de) 2020-11-06 2023-09-13 Incyte Corporation Verfahren zur herstellung eines pd-1/pd-l1-inhibitors sowie salze und kristalline formen davon
WO2022099018A1 (en) 2020-11-06 2022-05-12 Incyte Corporation Process of preparing a pd-1/pd-l1 inhibitor
US11760756B2 (en) 2020-11-06 2023-09-19 Incyte Corporation Crystalline form of a PD-1/PD-L1 inhibitor

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Also Published As

Publication number Publication date
JP4219171B2 (ja) 2009-02-04
US7141569B2 (en) 2006-11-28
US20040167335A1 (en) 2004-08-26
DE60212949D1 (de) 2006-08-17
EP1377575A1 (de) 2004-01-07
EP1377575B1 (de) 2006-07-05
WO2002083672A1 (en) 2002-10-24
US20060235043A1 (en) 2006-10-19
DE60212949T2 (de) 2007-01-04
JP2004529926A (ja) 2004-09-30
ES2266487T3 (es) 2007-03-01

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