RU2348617C2 - Производные 2-пиридона в качестве ингибиторов эластазы нейтрофилов и их применение - Google Patents

Производные 2-пиридона в качестве ингибиторов эластазы нейтрофилов и их применение Download PDF

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Publication number
RU2348617C2
RU2348617C2 RU2006112427/04A RU2006112427A RU2348617C2 RU 2348617 C2 RU2348617 C2 RU 2348617C2 RU 2006112427/04 A RU2006112427/04 A RU 2006112427/04A RU 2006112427 A RU2006112427 A RU 2006112427A RU 2348617 C2 RU2348617 C2 RU 2348617C2
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alkyl
optionally further
independently selected
further substituted
alkoxy
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RU2006112427/04A
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RU2006112427A (ru
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Петер ХАНСЕН (SE)
Петер Хансен
Каролина ЛАВИТЦ (SE)
Каролина ЛАВИТЦ
Ханс ЛЁНН (SE)
Ханс Лённ
Антониос НИКИТИДИС (SE)
Антониос Никитидис
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Астразенека Аб
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
RU2006112427/04A 2003-09-18 2004-09-15 Производные 2-пиридона в качестве ингибиторов эластазы нейтрофилов и их применение RU2348617C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0302487A SE0302487D0 (sv) 2003-09-18 2003-09-18 Novel compounds
SE0302487-4 2003-09-18

Publications (2)

Publication Number Publication Date
RU2006112427A RU2006112427A (ru) 2007-11-10
RU2348617C2 true RU2348617C2 (ru) 2009-03-10

Family

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RU2006112427/04A RU2348617C2 (ru) 2003-09-18 2004-09-15 Производные 2-пиридона в качестве ингибиторов эластазы нейтрофилов и их применение

Country Status (25)

Country Link
US (1) US20070043036A1 (cg-RX-API-DMAC7.html)
EP (1) EP1663974B1 (cg-RX-API-DMAC7.html)
JP (1) JP2007505902A (cg-RX-API-DMAC7.html)
KR (1) KR20060096995A (cg-RX-API-DMAC7.html)
CN (1) CN100439339C (cg-RX-API-DMAC7.html)
AR (1) AR046083A1 (cg-RX-API-DMAC7.html)
AT (1) ATE420861T1 (cg-RX-API-DMAC7.html)
AU (1) AU2004272485B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0414570A (cg-RX-API-DMAC7.html)
CA (1) CA2538410A1 (cg-RX-API-DMAC7.html)
CO (1) CO5670357A2 (cg-RX-API-DMAC7.html)
DE (1) DE602004019110D1 (cg-RX-API-DMAC7.html)
ES (1) ES2319300T3 (cg-RX-API-DMAC7.html)
IL (1) IL173986A0 (cg-RX-API-DMAC7.html)
IS (1) IS8394A (cg-RX-API-DMAC7.html)
MX (1) MXPA06002723A (cg-RX-API-DMAC7.html)
NO (1) NO20061700L (cg-RX-API-DMAC7.html)
RU (1) RU2348617C2 (cg-RX-API-DMAC7.html)
SA (1) SA04250300B1 (cg-RX-API-DMAC7.html)
SE (1) SE0302487D0 (cg-RX-API-DMAC7.html)
TW (1) TW200526579A (cg-RX-API-DMAC7.html)
UA (1) UA84878C2 (cg-RX-API-DMAC7.html)
UY (1) UY28513A1 (cg-RX-API-DMAC7.html)
WO (1) WO2005026124A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA200602262B (cg-RX-API-DMAC7.html)

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US5521179A (en) * 1991-04-18 1996-05-28 Zeneca Limited Heterocyclic amides
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RU96113098A (ru) * 1993-11-19 1998-09-27 Парк, Дэвис энд Компани Производные 5,6-дигидропирона в качестве ингибитора протеазы и антивирусные средства
RU2124004C1 (ru) * 1992-02-07 1998-12-27 Руссель-Юклаф Производные пиридона, способ их получения и фармацевтическая композиция на их основе
WO2002053543A1 (en) * 2000-12-28 2002-07-11 Shionogi & Co., Ltd. Pyridone derivative having affinity for cannabinoid 2-type receptor
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US5521179A (en) * 1991-04-18 1996-05-28 Zeneca Limited Heterocyclic amides
RU2124004C1 (ru) * 1992-02-07 1998-12-27 Руссель-Юклаф Производные пиридона, способ их получения и фармацевтическая композиция на их основе
RU96113098A (ru) * 1993-11-19 1998-09-27 Парк, Дэвис энд Компани Производные 5,6-дигидропирона в качестве ингибитора протеазы и антивирусные средства
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CO5670357A2 (es) 2006-08-31
UY28513A1 (es) 2005-04-29
MXPA06002723A (es) 2006-06-06
CA2538410A1 (en) 2005-03-24
SE0302487D0 (sv) 2003-09-18
CN100439339C (zh) 2008-12-03
DE602004019110D1 (de) 2009-03-05
AU2004272485B2 (en) 2008-03-13
UA84878C2 (ru) 2008-12-10
KR20060096995A (ko) 2006-09-13
IL173986A0 (en) 2006-07-05
HK1089167A1 (en) 2006-11-24
AU2004272485A1 (en) 2005-03-24
EP1663974B1 (en) 2009-01-14
CN1856467A (zh) 2006-11-01
TW200526579A (en) 2005-08-16
WO2005026124A1 (en) 2005-03-24
ES2319300T3 (es) 2009-05-06
RU2006112427A (ru) 2007-11-10
NO20061700L (no) 2006-04-18
SA04250300B1 (ar) 2008-09-07
JP2007505902A (ja) 2007-03-15
ATE420861T1 (de) 2009-01-15
US20070043036A1 (en) 2007-02-22
BRPI0414570A (pt) 2006-11-07
AR046083A1 (es) 2005-11-23
ZA200602262B (en) 2007-07-25
IS8394A (is) 2006-03-31
EP1663974A1 (en) 2006-06-07

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