IS8394A - 2-pýridónafleiður sem daukyrningselastasatálmar og notkun þeirra - Google Patents

2-pýridónafleiður sem daukyrningselastasatálmar og notkun þeirra

Info

Publication number
IS8394A
IS8394A IS8394A IS8394A IS8394A IS 8394 A IS8394 A IS 8394A IS 8394 A IS8394 A IS 8394A IS 8394 A IS8394 A IS 8394A IS 8394 A IS8394 A IS 8394A
Authority
IS
Iceland
Prior art keywords
neutrophil elastase
elastase inhibitors
pyridone derivatives
pyridone
derivatives
Prior art date
Application number
IS8394A
Other languages
English (en)
Inventor
Hansen Peter
Lawitz Karolina
Lönn Hans
Nikitidis Antonios
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=29212489&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS8394(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of IS8394A publication Critical patent/IS8394A/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84Nitriles
    • C07D213/85Nitriles in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IS8394A 2003-09-18 2006-03-31 2-pýridónafleiður sem daukyrningselastasatálmar og notkun þeirra IS8394A (is)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE0302487A SE0302487D0 (sv) 2003-09-18 2003-09-18 Novel compounds
PCT/SE2004/001336 WO2005026124A1 (en) 2003-09-18 2004-09-15 2-pyridone derivatives as netrophil elastase inhibitors and their use

Publications (1)

Publication Number Publication Date
IS8394A true IS8394A (is) 2006-03-31

Family

ID=29212489

Family Applications (1)

Application Number Title Priority Date Filing Date
IS8394A IS8394A (is) 2003-09-18 2006-03-31 2-pýridónafleiður sem daukyrningselastasatálmar og notkun þeirra

Country Status (25)

Country Link
US (1) US20070043036A1 (is)
EP (1) EP1663974B1 (is)
JP (1) JP2007505902A (is)
KR (1) KR20060096995A (is)
CN (1) CN100439339C (is)
AR (1) AR046083A1 (is)
AT (1) ATE420861T1 (is)
AU (1) AU2004272485B2 (is)
BR (1) BRPI0414570A (is)
CA (1) CA2538410A1 (is)
CO (1) CO5670357A2 (is)
DE (1) DE602004019110D1 (is)
ES (1) ES2319300T3 (is)
IL (1) IL173986A0 (is)
IS (1) IS8394A (is)
MX (1) MXPA06002723A (is)
NO (1) NO20061700L (is)
RU (1) RU2348617C2 (is)
SA (1) SA04250300B1 (is)
SE (1) SE0302487D0 (is)
TW (1) TW200526579A (is)
UA (1) UA84878C2 (is)
UY (1) UY28513A1 (is)
WO (1) WO2005026124A1 (is)
ZA (1) ZA200602262B (is)

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ES2386340T3 (es) 2007-12-14 2012-08-17 Pulmagen Therapeutics (Asthma) Limited Indoles y su uso terapéutico
AU2009206440B2 (en) 2008-01-23 2013-08-15 Bristol-Myers Squibb Company 4-pyridinone compounds and their use for cancer
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GB0902648D0 (en) 2009-02-17 2009-04-01 Argenta Discovery Ltd Pharmaceutical compounds and compositions
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EA025268B1 (ru) 2011-12-09 2016-12-30 Кьези Фармачеутичи С. П. А. Ингибиторы киназ
WO2013083206A1 (en) 2011-12-09 2013-06-13 Chiesi Farmaceutici S.P.A. Derivatives of 4-hydroxy-1,2,3,4-tetrahydronaphtalen-1-yl urea and their use in the treatment of, inter alia, diseases of the respiratory tract
JP6145849B2 (ja) 2011-12-09 2017-06-14 チエシ ファルマスーティシ エス.ピー.エー. キナーゼ阻害剤
US20140057926A1 (en) 2012-08-23 2014-02-27 Boehringer Ingelheim International Gmbh Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
US9102624B2 (en) 2012-08-23 2015-08-11 Boehringer Ingelheim International Gmbh Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
US20140057920A1 (en) 2012-08-23 2014-02-27 Boehringer Ingelheim International Gmbh Substituted 4-pyridones and their use as inhibitors of neutrophil elastase activity
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
AR096532A1 (es) 2013-06-06 2016-01-13 Chiesi Farm Spa Inhibidores de quinasa
US9221807B2 (en) * 2014-02-21 2015-12-29 Boehringer Ingelheim International Gmbh Substituted pyridones and pyrazinones and their use as inhibitors of neutrophil elastase activity
MX382781B (es) 2014-04-02 2025-03-13 Intermune Inc Piridinonas anti-fibroticas.
CR20180138A (es) 2015-09-02 2018-07-16 Glaxosmithkline Ip No 2 Ltd Piridinona dicaboxamidas para uso como inhibidores de bromodominio
TW201720828A (zh) 2015-11-23 2017-06-16 赫孚孟拉羅股份公司 治療性化合物及組合物以及其使用方法
AR107164A1 (es) 2015-12-23 2018-03-28 Chiesi Farm Spa INHIBIDORES DE QUINASA p38
AR107163A1 (es) 2015-12-23 2018-03-28 Chiesi Farm Spa Inhibidores de quinasa
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Also Published As

Publication number Publication date
ZA200602262B (en) 2007-07-25
EP1663974A1 (en) 2006-06-07
ATE420861T1 (de) 2009-01-15
CO5670357A2 (es) 2006-08-31
WO2005026124A1 (en) 2005-03-24
UA84878C2 (ru) 2008-12-10
AR046083A1 (es) 2005-11-23
EP1663974B1 (en) 2009-01-14
HK1089167A1 (en) 2006-11-24
CN1856467A (zh) 2006-11-01
AU2004272485A1 (en) 2005-03-24
IL173986A0 (en) 2006-07-05
SE0302487D0 (sv) 2003-09-18
BRPI0414570A (pt) 2006-11-07
NO20061700L (no) 2006-04-18
UY28513A1 (es) 2005-04-29
CN100439339C (zh) 2008-12-03
AU2004272485B2 (en) 2008-03-13
KR20060096995A (ko) 2006-09-13
RU2348617C2 (ru) 2009-03-10
MXPA06002723A (es) 2006-06-06
DE602004019110D1 (de) 2009-03-05
TW200526579A (en) 2005-08-16
RU2006112427A (ru) 2007-11-10
JP2007505902A (ja) 2007-03-15
ES2319300T3 (es) 2009-05-06
SA04250300B1 (ar) 2008-09-07
CA2538410A1 (en) 2005-03-24
US20070043036A1 (en) 2007-02-22

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