RU2346945C2 - Производные n-гетероциклилметилбензамидов, их получение и их применение в терапии - Google Patents

Производные n-гетероциклилметилбензамидов, их получение и их применение в терапии Download PDF

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Publication number
RU2346945C2
RU2346945C2 RU2006116889/04A RU2006116889A RU2346945C2 RU 2346945 C2 RU2346945 C2 RU 2346945C2 RU 2006116889/04 A RU2006116889/04 A RU 2006116889/04A RU 2006116889 A RU2006116889 A RU 2006116889A RU 2346945 C2 RU2346945 C2 RU 2346945C2
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Russia
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group
oct
azabicyclo
threo
hydrochloride
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RU2006116889/04A
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English (en)
Russian (ru)
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RU2006116889A (ru
Inventor
Жиад ДАРГАЗАНЛИ (FR)
Жиад Даргазанли
Женевьев ЭСТЕНН-БУТУ (FR)
Женевьев Эстенн-Буту
Паскаль МАГА (FR)
Паскаль Мага
Бенуа МАРАБУ (FR)
Бенуа Марабу
Пьер РОЖЕР (FR)
Пьер РОЖЕР
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Санофи-Авентис
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
RU2006116889/04A 2003-10-17 2004-10-15 Производные n-гетероциклилметилбензамидов, их получение и их применение в терапии RU2346945C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0312165 2003-10-17
FR0312165A FR2861076B1 (fr) 2003-10-17 2003-10-17 Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
RU2006116889A RU2006116889A (ru) 2007-11-27
RU2346945C2 true RU2346945C2 (ru) 2009-02-20

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RU2006116889/04A RU2346945C2 (ru) 2003-10-17 2004-10-15 Производные n-гетероциклилметилбензамидов, их получение и их применение в терапии

Country Status (32)

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US (3) US7288656B2 (cg-RX-API-DMAC10.html)
EP (1) EP1680421B1 (cg-RX-API-DMAC10.html)
JP (1) JP4853918B2 (cg-RX-API-DMAC10.html)
KR (1) KR101125305B1 (cg-RX-API-DMAC10.html)
CN (2) CN101684118B (cg-RX-API-DMAC10.html)
AT (1) ATE386036T1 (cg-RX-API-DMAC10.html)
AU (1) AU2004281217B2 (cg-RX-API-DMAC10.html)
BR (1) BRPI0415489A (cg-RX-API-DMAC10.html)
CA (1) CA2542647C (cg-RX-API-DMAC10.html)
CR (1) CR8342A (cg-RX-API-DMAC10.html)
CY (1) CY1108925T1 (cg-RX-API-DMAC10.html)
DE (1) DE602004011806T2 (cg-RX-API-DMAC10.html)
DK (1) DK1680421T3 (cg-RX-API-DMAC10.html)
EC (1) ECSP066511A (cg-RX-API-DMAC10.html)
ES (1) ES2300837T3 (cg-RX-API-DMAC10.html)
FR (1) FR2861076B1 (cg-RX-API-DMAC10.html)
HR (1) HRP20080186T3 (cg-RX-API-DMAC10.html)
IL (1) IL174940A (cg-RX-API-DMAC10.html)
MA (1) MA28099A1 (cg-RX-API-DMAC10.html)
ME (1) ME00111B (cg-RX-API-DMAC10.html)
NO (1) NO335462B1 (cg-RX-API-DMAC10.html)
NZ (1) NZ547163A (cg-RX-API-DMAC10.html)
OA (1) OA13317A (cg-RX-API-DMAC10.html)
PL (1) PL1680421T3 (cg-RX-API-DMAC10.html)
PT (1) PT1680421E (cg-RX-API-DMAC10.html)
RS (2) RS51587B (cg-RX-API-DMAC10.html)
RU (1) RU2346945C2 (cg-RX-API-DMAC10.html)
SG (1) SG147435A1 (cg-RX-API-DMAC10.html)
TN (1) TNSN06110A1 (cg-RX-API-DMAC10.html)
UA (1) UA81186C2 (cg-RX-API-DMAC10.html)
WO (1) WO2005037783A2 (cg-RX-API-DMAC10.html)
ZA (1) ZA200603861B (cg-RX-API-DMAC10.html)

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FR2861076B1 (fr) 2003-10-17 2006-01-06 Sanofi Synthelabo Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique
FR2861071B1 (fr) * 2003-10-17 2006-01-06 Sanofi Synthelabo Derives de n-[phenyl(alkylpiperidin-2-yl) methyl]benzamide, leur prepartation et leur application en therapeutique
FR2861074B1 (fr) * 2003-10-17 2006-04-07 Sanofi Synthelabo Derives de n-[phenyl(piperidin-2-yl)methyl]benzamide, leur preparation et leur application en therapeutique
JP2007530664A (ja) * 2004-03-30 2007-11-01 ペインセプター ファーマ コーポレーション ゲートイオンチャンネルを調節するための組成物及び方法
FR2906251B1 (fr) 2006-09-22 2008-11-07 Sanofi Aventis Sa Derives de pyrrolizine, indolizine et quinolizine, leur preparation et leur application en therapeutique
US11817637B2 (en) 2006-11-18 2023-11-14 Rfmicron, Inc. Radio frequency identification (RFID) moisture tag(s) and sensors with extended sensing via capillaries
TW200911808A (en) * 2007-07-23 2009-03-16 Astrazeneca Ab Novel compounds
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JP2012511006A (ja) * 2008-12-04 2012-05-17 サノフイ アザビシクロ−トリフルオロメチルベンズアミド誘導体の新規な結晶多形
WO2010087761A1 (en) * 2009-01-28 2010-08-05 Astrazeneca Ab 2-aza-bicyclo[2.2.2]octane compounds and uses thereof
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FR2944284A1 (fr) * 2009-04-14 2010-10-15 Sanofi Aventis Derives de n-°7-aza-bicyclo°2.2.1!hept-1-yl)-aryl-methyl! -benzamide, leur preparation et leur application en therapeutique
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US8883839B2 (en) 2010-08-13 2014-11-11 Abbott Laboratories Tetraline and indane derivatives, pharmaceutical compositions containing them, and their use in therapy
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US8846743B2 (en) 2010-08-13 2014-09-30 Abbott Laboratories Aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
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CN104011028A (zh) 2011-11-18 2014-08-27 艾伯维德国有限责任两合公司 N-取代的氨基苯并环庚烯、氨基四氢化萘、氨基茚满和苯烷基胺衍生物、包含所述衍生物的药物组合物及其在治疗中的用途
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US9365512B2 (en) 2012-02-13 2016-06-14 AbbVie Deutschland GmbH & Co. KG Isoindoline derivatives, pharmaceutical compositions containing them, and their use in therapy
US9656955B2 (en) 2013-03-15 2017-05-23 Abbvie Inc. Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
US9650334B2 (en) 2013-03-15 2017-05-16 Abbvie Inc. Pyrrolidine derivatives, pharmaceutical compositions containing them, and their use in therapy
EP3057958B1 (en) 2013-10-17 2019-05-01 AbbVie Deutschland GmbH & Co. KG Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy
CN105992764A (zh) 2013-10-17 2016-10-05 艾伯维德国有限责任两合公司 氨基色满、氨基硫代色满及氨基-1,2,3,4-四氢喹啉衍生物，包含其的药物组合物及其在治疗中的用途
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WO2016060938A2 (en) 2014-10-08 2016-04-21 RF Micron, Inc. Radio frequency identification (rfid) moisture tag(s) and sensors with extended sensing via capillaries
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Publication number Publication date
JP2007508361A (ja) 2007-04-05
RS51587B (sr) 2011-08-31
CA2542647C (fr) 2012-07-10
RU2006116889A (ru) 2007-11-27
DK1680421T3 (da) 2008-06-09
MA28099A1 (fr) 2006-08-01
CY1108925T1 (el) 2014-07-02
WO2005037783A3 (fr) 2005-07-07
NZ547163A (en) 2010-01-29
MEP12208A (en) 2010-06-10
NO335462B1 (no) 2014-12-15
KR20060109432A (ko) 2006-10-20
CN101684118B (zh) 2013-04-10
ZA200603861B (en) 2007-12-27
IL174940A (en) 2010-11-30
DE602004011806D1 (de) 2008-03-27
WO2005037783A2 (fr) 2005-04-28
PL1680421T3 (pl) 2008-07-31
CN1882587A (zh) 2006-12-20
US20060264441A1 (en) 2006-11-23
UA81186C2 (en) 2007-12-10
JP4853918B2 (ja) 2012-01-11
US20080070941A1 (en) 2008-03-20
FR2861076A1 (fr) 2005-04-22
US7288656B2 (en) 2007-10-30
CA2542647A1 (fr) 2005-04-28
ES2300837T3 (es) 2008-06-16
DE602004011806T2 (de) 2009-02-05
ME00111B (me) 2010-10-10
CN101684118A (zh) 2010-03-31
US8513246B2 (en) 2013-08-20
AU2004281217A1 (en) 2005-04-28
SG147435A1 (en) 2008-11-28
ATE386036T1 (de) 2008-03-15
US7619089B2 (en) 2009-11-17
EP1680421A2 (fr) 2006-07-19
OA13317A (fr) 2007-04-13
ECSP066511A (es) 2006-10-10
HK1098465A1 (en) 2007-07-20
HRP20080186T3 (en) 2008-05-31
US20100022548A1 (en) 2010-01-28
PT1680421E (pt) 2008-05-13
AU2004281217B2 (en) 2010-07-22
IL174940A0 (en) 2006-08-20
NO20062030L (no) 2006-07-07
BRPI0415489A (pt) 2006-12-26
HK1142887A1 (en) 2010-12-17
RS20060314A (sr) 2008-08-07
CN1882587B (zh) 2012-06-27
FR2861076B1 (fr) 2006-01-06
CR8342A (es) 2006-10-04
EP1680421B1 (fr) 2008-02-13
KR101125305B1 (ko) 2012-03-27
TNSN06110A1 (fr) 2007-11-15

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