RU2338751C2 - СПОСОБЫ ИДЕНТИФИКАЦИИ ОПУХОЛЕЙ, ВОСПРИИМЧИВЫХ К ЛЕЧЕНИЮ АНТИТЕЛАМИ ПРОТИВ ErbB2 - Google Patents

СПОСОБЫ ИДЕНТИФИКАЦИИ ОПУХОЛЕЙ, ВОСПРИИМЧИВЫХ К ЛЕЧЕНИЮ АНТИТЕЛАМИ ПРОТИВ ErbB2 Download PDF

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RU2338751C2
RU2338751C2 RU2005103824/13A RU2005103824A RU2338751C2 RU 2338751 C2 RU2338751 C2 RU 2338751C2 RU 2005103824/13 A RU2005103824/13 A RU 2005103824/13A RU 2005103824 A RU2005103824 A RU 2005103824A RU 2338751 C2 RU2338751 C2 RU 2338751C2
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antibody
her2
tumor
erbb2
antibodies
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RU2005103824/13A
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RU2005103824A (ru
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Ханс КОЛЛЬ (DE)
Ханс КОЛЛЬ
Биргит БОССЕНМАЙЕР (DE)
Биргит БОССЕНМАЙЕР
Ханс-Йоахим МЮЛЛЕР (DE)
Ханс-Йоахим Мюллер
Марк К. СЛИВКОВСКИ (US)
Марк К. СЛИВКОВСКИ
Стефен Майкл КЕЛСИ (US)
Стефен Майкл КЕЛСИ
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Дженентек, Инк.
Ф.Хоффманн-Ля Рош Аг
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Application filed by Дженентек, Инк., Ф.Хоффманн-Ля Рош Аг filed Critical Дженентек, Инк.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/485—Epidermal growth factor [EGF] (urogastrone)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
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  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
RU2005103824/13A 2002-07-15 2003-07-11 СПОСОБЫ ИДЕНТИФИКАЦИИ ОПУХОЛЕЙ, ВОСПРИИМЧИВЫХ К ЛЕЧЕНИЮ АНТИТЕЛАМИ ПРОТИВ ErbB2 RU2338751C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US39629002P 2002-07-15 2002-07-15
US60/396,290 2002-07-15
US48004303P 2003-06-20 2003-06-20
US60/480,043 2003-06-20

Related Child Applications (1)

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RU2008128244/13A Division RU2008128244A (ru) 2002-07-15 2008-07-10 Способы идентификации опухолей, восприимчивых к лечению антителами против erbb2

Publications (2)

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RU2005103824A RU2005103824A (ru) 2005-08-27
RU2338751C2 true RU2338751C2 (ru) 2008-11-20

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RU2005103824/13A RU2338751C2 (ru) 2002-07-15 2003-07-11 СПОСОБЫ ИДЕНТИФИКАЦИИ ОПУХОЛЕЙ, ВОСПРИИМЧИВЫХ К ЛЕЧЕНИЮ АНТИТЕЛАМИ ПРОТИВ ErbB2
RU2008128244/13A RU2008128244A (ru) 2002-07-15 2008-07-10 Способы идентификации опухолей, восприимчивых к лечению антителами против erbb2

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RU2008128244/13A RU2008128244A (ru) 2002-07-15 2008-07-10 Способы идентификации опухолей, восприимчивых к лечению антителами против erbb2

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US (2) US20040106161A1 (enExample)
EP (2) EP2263691B1 (enExample)
JP (3) JP5069843B2 (enExample)
CN (2) CN102295703A (enExample)
AT (1) ATE535254T1 (enExample)
AU (2) AU2003273218C1 (enExample)
BR (1) BR0312534A (enExample)
CA (1) CA2490758C (enExample)
CY (2) CY1112631T1 (enExample)
DK (2) DK1585966T3 (enExample)
ES (2) ES2376165T3 (enExample)
HU (1) HUP0600340A3 (enExample)
IL (2) IL165952A (enExample)
MX (1) MXPA05000403A (enExample)
NO (1) NO337855B1 (enExample)
NZ (1) NZ537660A (enExample)
PL (1) PL214010B1 (enExample)
PT (2) PT2263691E (enExample)
RU (2) RU2338751C2 (enExample)
WO (1) WO2004008099A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2411915C1 (ru) * 2009-10-05 2011-02-20 Константин Петрович Гайденко Способ диагностики больных, пораженных опухолями головного мозга
RU2620068C2 (ru) * 2011-11-23 2017-05-22 МЕДИММЬЮН, ЭлЭлСи Связывающие молекулы, специфичные по отношению к her3, и их применения

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HUP0600340A2 (en) 2006-08-28
AU2003273218B2 (en) 2009-11-26
PT1585966E (pt) 2012-02-20
JP2014237667A (ja) 2014-12-18
CN101711866A (zh) 2010-05-26
AU2010200692A1 (en) 2010-03-18
PT2263691E (pt) 2012-11-12
RU2005103824A (ru) 2005-08-27
CA2490758C (en) 2014-09-23
EP2263691B1 (en) 2012-08-29
NO20050775L (no) 2005-02-14
MXPA05000403A (es) 2005-07-22
HUP0600340A3 (en) 2011-06-28
JP5678005B2 (ja) 2015-02-25
IL219381A0 (en) 2012-06-28
JP2006508336A (ja) 2006-03-09
EP2263691A1 (en) 2010-12-22
IL165952A0 (en) 2006-01-15
DK2263691T3 (da) 2012-10-22
CA2490758A1 (en) 2004-01-22
EP1585966B1 (en) 2011-11-30
WO2004008099A2 (en) 2004-01-22
NO337855B1 (no) 2016-07-04
ES2376165T3 (es) 2012-03-09

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