ATE442589T1 - Nachweis der rezeptoroligomerisierung - Google Patents

Nachweis der rezeptoroligomerisierung

Info

Publication number
ATE442589T1
ATE442589T1 AT03771670T AT03771670T ATE442589T1 AT E442589 T1 ATE442589 T1 AT E442589T1 AT 03771670 T AT03771670 T AT 03771670T AT 03771670 T AT03771670 T AT 03771670T AT E442589 T1 ATE442589 T1 AT E442589T1
Authority
AT
Austria
Prior art keywords
probes
binding
molecules
probe includes
cleaving
Prior art date
Application number
AT03771670T
Other languages
English (en)
Inventor
Po-Ying Chan-Hui
Yining Shi
Sailaja Pidaparthi
Rajiv Dua
Sharat Singh
Original Assignee
Aclara Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aclara Biosciences Inc filed Critical Aclara Biosciences Inc
Application granted granted Critical
Publication of ATE442589T1 publication Critical patent/ATE442589T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
AT03771670T 2002-07-25 2003-07-17 Nachweis der rezeptoroligomerisierung ATE442589T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39872402P 2002-07-25 2002-07-25
PCT/US2003/022611 WO2004011900A2 (en) 2002-07-25 2003-07-17 Detecting receptor oligomerization

Publications (1)

Publication Number Publication Date
ATE442589T1 true ATE442589T1 (de) 2009-09-15

Family

ID=31188464

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03771670T ATE442589T1 (de) 2002-07-25 2003-07-17 Nachweis der rezeptoroligomerisierung

Country Status (13)

Country Link
US (2) US7105308B2 (de)
EP (1) EP1540347B1 (de)
JP (2) JP4443407B2 (de)
KR (1) KR20050025669A (de)
CN (1) CN1672054A (de)
AT (1) ATE442589T1 (de)
AU (1) AU2003259175B2 (de)
CA (1) CA2490654C (de)
DE (1) DE60329194D1 (de)
ES (1) ES2332310T3 (de)
NO (1) NO20050916L (de)
PL (1) PL374875A1 (de)
WO (1) WO2004011900A2 (de)

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US7402398B2 (en) 2003-07-17 2008-07-22 Monogram Biosciences, Inc. Measuring receptor homodimerization
US20100291594A1 (en) * 2003-07-17 2010-11-18 Laboratory Corporation Of America Holdings ErbB Surface Receptor Complexes as Biomarkers
WO2005019470A2 (en) 2003-08-11 2005-03-03 Monogram Biosciences, Inc. Detecting and profiling molecular complexes
EP1681983A4 (de) * 2003-10-14 2008-12-10 Monogram Biosciences Inc Rezeptor-tyrosin-kinase-signalpfad-analyse für diagnose und therapie
US8282921B2 (en) 2004-08-02 2012-10-09 Paul Glidden tRNA synthetase fragments
US7939267B2 (en) * 2004-11-04 2011-05-10 Laboratory Corporation Of America Holdings Detection of activation of endothelial cells as surrogate marker for angiogenesis
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US8357277B2 (en) 2007-11-27 2013-01-22 Laboratory Corp. of America Holdings Enhanced method for detecting and/or quantifying an analyte in a sample
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ES2526519T3 (es) * 2009-01-15 2015-01-13 Laboratory Corporation Of America Holdings Métodos de determinación de la respuesta del paciente por medición de la expresión HER-2
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SG194609A1 (en) 2011-05-19 2013-12-30 Lab Corp America Holdings Methods for determining the likelihood of survival and for predicting likelihood of metastasis in cancer patients
US9442098B2 (en) * 2012-08-02 2016-09-13 Waters Technologies Corporation Chromatographic system quality control reference materials
CN103012193B (zh) * 2012-12-14 2015-08-19 无锡中德伯尔生物技术有限公司 隐色孔雀石绿半抗原、人工抗原及制备方法
WO2014165855A1 (en) 2013-04-05 2014-10-09 Laboratory Corporation Of America Holdings Systems and methods for facilitating diagnosis, prognosis and treatment of cancer based on detection of her3 activation
WO2015038799A1 (en) * 2013-09-11 2015-03-19 Moy Ronald L Systems and methods for the molecular quantification of skin damage in skin
CN104458708A (zh) * 2013-09-12 2015-03-25 中国药科大学 一种筛选乙酰胆碱酯酶抑制剂高通量筛选方法
EP3050886A1 (de) * 2015-02-02 2016-08-03 Bürkert Werke GmbH Fluoreszenzfarbstoffe und Farbstoffvorläufer
WO2017161030A1 (en) 2016-03-15 2017-09-21 Laboratory Corporation Of America Holdings Methods of assessing protein interactions between cells
CN105891347B (zh) * 2016-03-18 2018-02-13 宁波大学 一种胶束电动毛细管电泳法测定γ‑氨基丁酸含量的方法
US20200016594A1 (en) * 2016-09-30 2020-01-16 The Governing Council Of The University Of Toronto System for identifying and targeting individual cells within a heterogeneous population for selective extraction of cellular content
CN111276385B (zh) * 2020-02-13 2020-12-08 清华大学 质谱仪的离子激发检测方法
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Also Published As

Publication number Publication date
WO2004011900A3 (en) 2004-06-10
DE60329194D1 (de) 2009-10-22
US20040126818A1 (en) 2004-07-01
EP1540347A4 (de) 2006-09-20
NO20050916L (no) 2005-04-14
CA2490654C (en) 2012-02-07
US7105308B2 (en) 2006-09-12
CA2490654A1 (en) 2004-02-05
EP1540347A2 (de) 2005-06-15
KR20050025669A (ko) 2005-03-14
CN1672054A (zh) 2005-09-21
JP4443407B2 (ja) 2010-03-31
ES2332310T3 (es) 2010-02-02
AU2003259175B2 (en) 2010-08-12
JP2005534030A (ja) 2005-11-10
EP1540347B1 (de) 2009-09-09
US20040197835A1 (en) 2004-10-07
WO2004011900A2 (en) 2004-02-05
AU2003259175A1 (en) 2004-02-16
US7135300B2 (en) 2006-11-14
JP2009271087A (ja) 2009-11-19
PL374875A1 (en) 2005-11-14

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