RU2336871C2 - Применение соединений, которые являются эффективными как селективные модуляторы опиатного рецептора - Google Patents

Применение соединений, которые являются эффективными как селективные модуляторы опиатного рецептора Download PDF

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RU2336871C2
RU2336871C2 RU2004137091/15A RU2004137091A RU2336871C2 RU 2336871 C2 RU2336871 C2 RU 2336871C2 RU 2004137091/15 A RU2004137091/15 A RU 2004137091/15A RU 2004137091 A RU2004137091 A RU 2004137091A RU 2336871 C2 RU2336871 C2 RU 2336871C2
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colon
compounds
effective
pain
asimadoline
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RU2004137091/15A
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Russian (ru)
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RU2004137091A (ru
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Франк ВЕБЕР (DE)
Франк ВЕБЕР
Ютта ЯКОБ (DE)
Ютта ЯКОБ
Эндрью БАРБЕР (DE)
Эндрью БАРБЕР
Рудольф ГОТТШЛИХ (DE)
Рудольф ГОТТШЛИХ
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Тиога Фармасьютиклз, Инк.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU2004137091/15A 2002-05-17 2003-04-28 Применение соединений, которые являются эффективными как селективные модуляторы опиатного рецептора RU2336871C2 (ru)

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Application Number Priority Date Filing Date Title
EP02011047 2002-05-17
EP02011047.4 2002-05-17

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RU2004137091A RU2004137091A (ru) 2005-09-10
RU2336871C2 true RU2336871C2 (ru) 2008-10-27

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US (1) US20050176746A1 (enExample)
EP (2) EP2074997A1 (enExample)
JP (1) JP2005531557A (enExample)
KR (1) KR101108014B1 (enExample)
CN (2) CN101310723A (enExample)
AR (1) AR040028A1 (enExample)
AT (1) ATE429226T1 (enExample)
AU (1) AU2003242527B2 (enExample)
BR (1) BR0309969A (enExample)
CA (1) CA2486000A1 (enExample)
DE (1) DE60327315D1 (enExample)
DK (1) DK1505974T3 (enExample)
ES (1) ES2325782T3 (enExample)
MX (1) MXPA04011333A (enExample)
PE (1) PE20040455A1 (enExample)
PL (1) PL371596A1 (enExample)
RU (1) RU2336871C2 (enExample)
TW (1) TWI314053B (enExample)
WO (1) WO2003097051A2 (enExample)
ZA (1) ZA200410160B (enExample)

Cited By (1)

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EA023231B1 (ru) * 2013-07-18 2016-05-31 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт нормальной физиологии имени П.К. Анохина" Российской академии медицинских наук (ФГБУ "НИИНФ им. П.К. Анохина" РАМН) Применение агониста каппа опиоидных рецепторов периферического действия ici 204,448 для приготовления средств для лечения синдрома отмены никотина

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA023231B1 (ru) * 2013-07-18 2016-05-31 Федеральное государственное бюджетное учреждение "Научно-исследовательский институт нормальной физиологии имени П.К. Анохина" Российской академии медицинских наук (ФГБУ "НИИНФ им. П.К. Анохина" РАМН) Применение агониста каппа опиоидных рецепторов периферического действия ici 204,448 для приготовления средств для лечения синдрома отмены никотина

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EP2074997A1 (en) 2009-07-01
KR101108014B1 (ko) 2012-01-25
AU2003242527A1 (en) 2003-12-02
US20050176746A1 (en) 2005-08-11
AU2003242527B2 (en) 2008-10-23
MXPA04011333A (es) 2005-02-14
CN101310723A (zh) 2008-11-26
ES2325782T3 (es) 2009-09-17
ATE429226T1 (de) 2009-05-15
CN100411618C (zh) 2008-08-20
HK1079451A1 (zh) 2006-04-07
RU2004137091A (ru) 2005-09-10
CA2486000A1 (en) 2003-11-27
WO2003097051A2 (en) 2003-11-27
EP1505974B1 (en) 2009-04-22
CN1655784A (zh) 2005-08-17
TWI314053B (en) 2009-09-01
ZA200410160B (en) 2005-12-28
DK1505974T3 (da) 2009-08-17
KR20050010807A (ko) 2005-01-28
DE60327315D1 (de) 2009-06-04
BR0309969A (pt) 2005-04-26
TW200307541A (en) 2003-12-16
PE20040455A1 (es) 2004-08-07
PL371596A1 (en) 2005-06-27
JP2005531557A (ja) 2005-10-20
EP1505974A2 (en) 2005-02-16
AR040028A1 (es) 2005-03-09
WO2003097051A3 (en) 2004-12-09

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