AR040028A1 - Uso de compuestos que son efectivos como moduladores selectivos de receptores opiaceos - Google Patents

Uso de compuestos que son efectivos como moduladores selectivos de receptores opiaceos

Info

Publication number
AR040028A1
AR040028A1 ARP030101709A ARP030101709A AR040028A1 AR 040028 A1 AR040028 A1 AR 040028A1 AR P030101709 A ARP030101709 A AR P030101709A AR P030101709 A ARP030101709 A AR P030101709A AR 040028 A1 AR040028 A1 AR 040028A1
Authority
AR
Argentina
Prior art keywords
effective
compounds
disorders
adl
use according
Prior art date
Application number
ARP030101709A
Other languages
English (en)
Inventor
Barber Andrew Dr
Gottschlich Rudolf Dr
Weber Frank Dr
Jacob Jutta Dr
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of AR040028A1 publication Critical patent/AR040028A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Uso de compuestos que son efectivos como moduladores selectivos de receptores opiáceos para preparar productos farmacéuticos para el diagnóstico y/o el tratamiento de trastornos, siendo seleccionados dichos trastornos de trastornos alimentarios y trastornos digestivos, en especial, trastornos alimentarios psicogénicos, para preparar un producto farmacéutico efectivo para modular el tono gastrointestinal, y a composiciones farmacéuticas que comprenden uno o varios de dichos compuestos moduladores y uno o varios compuestos que son efectivos como supresores del apetito. Reivindicación 5: Uso de acuerdo con una de las reivindicaciones precedentes, caracterizado porque el compuesto se selecciona del grupo integrado por alvimopan, loperamida, asimadolina, fedotozina, pentazocina, U62066E, ICI204448, U-50488H, ADL 10-0101, ADL 10-0116 y ADL 1-0398. Reivindicación 9: Uso de acuerdo con la reivindicación 8, caracterizado porque el producto farmacéutico que es efectivo como supresor del apetito es un simpatomimético. Reivindicación 10: Uso de acuerdo con la reivindicación 8 o 9, caracterizado porque el producto farmacéutico que es efectivo como supresor del apetito se selecciona del grupo integrado por fenilpropanolamina, catina, sibutramina, anfepramona, efedrina y norseudoefedrina.
ARP030101709A 2002-05-17 2003-05-16 Uso de compuestos que son efectivos como moduladores selectivos de receptores opiaceos AR040028A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02011047 2002-05-17

Publications (1)

Publication Number Publication Date
AR040028A1 true AR040028A1 (es) 2005-03-09

Family

ID=29433078

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP030101709A AR040028A1 (es) 2002-05-17 2003-05-16 Uso de compuestos que son efectivos como moduladores selectivos de receptores opiaceos

Country Status (21)

Country Link
US (1) US20050176746A1 (es)
EP (2) EP2074997A1 (es)
JP (1) JP2005531557A (es)
KR (1) KR101108014B1 (es)
CN (2) CN101310723A (es)
AR (1) AR040028A1 (es)
AT (1) ATE429226T1 (es)
AU (1) AU2003242527B2 (es)
BR (1) BR0309969A (es)
CA (1) CA2486000A1 (es)
DE (1) DE60327315D1 (es)
DK (1) DK1505974T3 (es)
ES (1) ES2325782T3 (es)
HK (1) HK1079451A1 (es)
MX (1) MXPA04011333A (es)
PE (1) PE20040455A1 (es)
PL (1) PL371596A1 (es)
RU (1) RU2336871C2 (es)
TW (1) TWI314053B (es)
WO (1) WO2003097051A2 (es)
ZA (1) ZA200410160B (es)

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Also Published As

Publication number Publication date
TWI314053B (en) 2009-09-01
BR0309969A (pt) 2005-04-26
WO2003097051A2 (en) 2003-11-27
MXPA04011333A (es) 2005-02-14
ZA200410160B (en) 2005-12-28
CA2486000A1 (en) 2003-11-27
JP2005531557A (ja) 2005-10-20
DK1505974T3 (da) 2009-08-17
ATE429226T1 (de) 2009-05-15
EP1505974B1 (en) 2009-04-22
WO2003097051A3 (en) 2004-12-09
PL371596A1 (en) 2005-06-27
DE60327315D1 (de) 2009-06-04
RU2004137091A (ru) 2005-09-10
ES2325782T3 (es) 2009-09-17
AU2003242527B2 (en) 2008-10-23
US20050176746A1 (en) 2005-08-11
CN1655784A (zh) 2005-08-17
AU2003242527A1 (en) 2003-12-02
EP1505974A2 (en) 2005-02-16
KR20050010807A (ko) 2005-01-28
HK1079451A1 (en) 2006-04-07
EP2074997A1 (en) 2009-07-01
CN100411618C (zh) 2008-08-20
RU2336871C2 (ru) 2008-10-27
CN101310723A (zh) 2008-11-26
TW200307541A (en) 2003-12-16
PE20040455A1 (es) 2004-08-07
KR101108014B1 (ko) 2012-01-25

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