DE60207383D1 - Ibuprofen und diphenhydramin enthaltende zusammensetzungen und deren verwendung zur behandlung von schlafstörungen - Google Patents
Ibuprofen und diphenhydramin enthaltende zusammensetzungen und deren verwendung zur behandlung von schlafstörungenInfo
- Publication number
- DE60207383D1 DE60207383D1 DE60207383T DE60207383T DE60207383D1 DE 60207383 D1 DE60207383 D1 DE 60207383D1 DE 60207383 T DE60207383 T DE 60207383T DE 60207383 T DE60207383 T DE 60207383T DE 60207383 D1 DE60207383 D1 DE 60207383D1
- Authority
- DE
- Germany
- Prior art keywords
- diphenhydramine
- ibuprofen
- treatment
- sleep disorders
- containing compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
- A61K9/4825—Proteins, e.g. gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/485—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Inorganic Chemistry (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Anesthesiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26238701P | 2001-01-19 | 2001-01-19 | |
US262387P | 2001-01-19 | ||
PCT/US2002/003855 WO2002056877A1 (en) | 2001-01-19 | 2002-01-18 | Treatment of sleep disturbances |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60207383D1 true DE60207383D1 (de) | 2005-12-22 |
DE60207383T2 DE60207383T2 (de) | 2006-08-03 |
Family
ID=22997281
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60207383T Expired - Lifetime DE60207383T2 (de) | 2001-01-19 | 2002-01-18 | Ibuprofen und diphenhydramin enthaltende zusammensetzungen und deren verwendung zur behandlung von schlafstörungen |
Country Status (11)
Country | Link |
---|---|
US (4) | US20020177626A1 (de) |
EP (1) | EP1363608B1 (de) |
JP (2) | JP4402882B2 (de) |
AT (1) | ATE309797T1 (de) |
CA (1) | CA2434484C (de) |
DE (1) | DE60207383T2 (de) |
DK (1) | DK1363608T3 (de) |
ES (1) | ES2251584T3 (de) |
HK (1) | HK1060045A1 (de) |
MX (1) | MXPA03006364A (de) |
WO (1) | WO2002056877A1 (de) |
Families Citing this family (34)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020177626A1 (en) * | 2001-01-19 | 2002-11-28 | Cook Graham D. | Treatment of sleep disturbances |
JP5148801B2 (ja) * | 2002-09-09 | 2013-02-20 | エスエス製薬株式会社 | 催眠用固形製剤 |
DE10334187A1 (de) * | 2003-07-26 | 2005-03-03 | Schwarz Pharma Ag | Substituierte 2-Aminotetraline zur Behandlung von Depressionen |
DE10334188B4 (de) * | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
WO2005044199A2 (en) * | 2003-11-05 | 2005-05-19 | Santarus, Inc. | Combination of proton pump inhibitor and sleep aid |
JP2005281268A (ja) * | 2004-03-31 | 2005-10-13 | Taiyo Yakuhin Kogyo Kk | 経時安定な抗ヒスタミン類固形製剤 |
US20070259930A1 (en) * | 2006-04-10 | 2007-11-08 | Knopp Neurosciences, Inc. | Compositions and methods of using r(+) pramipexole |
US8518926B2 (en) | 2006-04-10 | 2013-08-27 | Knopp Neurosciences, Inc. | Compositions and methods of using (R)-pramipexole |
CA2652251A1 (en) | 2006-05-16 | 2007-11-29 | Knopp Neurosciences, Inc. | Compositions of r(+) and s(-) pramipexole and methods for using the same |
EP2497473A1 (de) | 2006-05-16 | 2012-09-12 | Knopp Neurosciences, Inc. | Therapeutisch wirksame Mengen von R(+)- und S(-)-Pramipexol zur Verwendung bei der Behandlung von Parkinson und pharmazeutische Zusammensetzungen davon |
US8524695B2 (en) | 2006-12-14 | 2013-09-03 | Knopp Neurosciences, Inc. | Modified release formulations of (6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine and methods of using the same |
JP2008184430A (ja) * | 2007-01-30 | 2008-08-14 | Ss Pharmaceut Co Ltd | ソフトカプセル |
WO2008113056A2 (en) * | 2007-03-14 | 2008-09-18 | Knopp Neurosciences, Inc. | Synthesis of chirally purified substituted benzothiazole diamines |
GB2447898B (en) * | 2007-03-24 | 2011-08-17 | Reckitt Benckiser Healthcare | A tablet having improved stability with at least two actives |
US20090214648A1 (en) * | 2008-02-15 | 2009-08-27 | Malathi Kandakatla | Pharmaceutical formulations comprising ibuprofen and diphenhydramine |
US20110190356A1 (en) | 2008-08-19 | 2011-08-04 | Knopp Neurosciences Inc. | Compositions and Methods of Using (R)- Pramipexole |
CN102802418A (zh) * | 2009-06-19 | 2012-11-28 | 诺普神经科学股份有限公司 | 用于治疗肌萎缩性侧索硬化的组合物和方法 |
LT2498758T (lt) * | 2009-11-13 | 2018-11-26 | Astrazeneca Ab | Dvisluoksnės tabletės formuluotės |
US20180264013A1 (en) * | 2010-07-08 | 2018-09-20 | Wellesley Pharmaceuticals, Llc | Composition and methods for treating sleep disorders |
JP5896645B2 (ja) * | 2010-08-26 | 2016-03-30 | 興和株式会社 | ロキソプロフェン又はその塩の含有医薬製剤 |
JP6110589B2 (ja) * | 2010-12-13 | 2017-04-05 | 第一三共ヘルスケア株式会社 | ロキソプロフェンナトリウムとクレマスチンフマル酸塩を含有する固形製剤 |
JP6106359B2 (ja) * | 2010-12-13 | 2017-03-29 | 第一三共ヘルスケア株式会社 | ロキソプロフェンナトリウムとビタミンb1を含有する固形製剤 |
JP6126780B2 (ja) * | 2010-12-13 | 2017-05-10 | 第一三共ヘルスケア株式会社 | ロキソプロフェンナトリウム及びトラネキサム酸を含有する固形製剤 |
JP6112765B2 (ja) * | 2010-12-13 | 2017-04-12 | 第一三共ヘルスケア株式会社 | ロキソプロフェンナトリウム及びdl−メチルエフェドリン塩酸塩を含有する固形製剤 |
CN102488680B (zh) * | 2011-12-21 | 2012-12-26 | 西南大学 | 布洛芬苯海拉明分散片及其制备方法 |
WO2013096816A1 (en) | 2011-12-22 | 2013-06-27 | Biogen Idec Ma Inc. | Improved synthesis of amine substituted 4,5,6,7-tetrahydrobenzothiazole compounds |
JP6160263B2 (ja) * | 2012-06-07 | 2017-07-12 | 大正製薬株式会社 | ロキソプロフェン含有医薬組成物 |
US9662313B2 (en) | 2013-02-28 | 2017-05-30 | Knopp Biosciences Llc | Compositions and methods for treating amyotrophic lateral sclerosis in responders |
US9468630B2 (en) | 2013-07-12 | 2016-10-18 | Knopp Biosciences Llc | Compositions and methods for treating conditions related to increased eosinophils |
CN105764507B (zh) | 2013-07-12 | 2019-07-19 | 诺普生物科学有限责任公司 | 治疗升高的嗜酸性粒细胞和/或嗜碱性粒细胞的水平 |
ES2871556T3 (es) | 2013-08-13 | 2021-10-29 | Knopp Biosciences Llc | Composiciones y métodos para el tratamiento de la urticaria crónica |
ES2813674T3 (es) | 2013-08-13 | 2021-03-24 | Knopp Biosciences Llc | Composiciones y métodos para el tratamiento de trastornos de células plasmáticas y trastornos prolinfocíticos de células b |
WO2019226150A1 (en) * | 2018-05-21 | 2019-11-28 | Wellesley Pharmaceuticals Inc. | Composition and methods for treating sleep disorders |
US20210282707A1 (en) | 2020-03-16 | 2021-09-16 | Koninklijke Philips N.V. | Detecting undiagnosed sleep disordered breathing using daytime sleepiness and nighttime obstructive sleep apnea (osa) severity |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4401665A (en) * | 1981-04-14 | 1983-08-30 | Bristol-Myers Company | Sleep-aid composition containing an analgesic and diphenhydramine dihydrogencitrate, and method of use |
US4464376A (en) | 1982-07-22 | 1984-08-07 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising caffeine and methods of using same |
US4420483A (en) | 1982-07-22 | 1983-12-13 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising ibuprofen and methods of using same |
US4755532A (en) | 1984-02-08 | 1988-07-05 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same |
US4985459A (en) * | 1984-02-08 | 1991-01-15 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same |
US4906625A (en) | 1984-02-08 | 1990-03-06 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising diphenhydramine and metyhods of using same |
US4585783A (en) | 1984-02-08 | 1986-04-29 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same |
US4522826A (en) * | 1984-02-08 | 1985-06-11 | Richardson-Vicks Inc. | Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same |
US4683243A (en) | 1984-02-08 | 1987-07-28 | Richardson-Vicks, Inc. | Analgesic and anti-inflammatory compositions comprising diphenhydramine and methods of using same |
US4552899A (en) | 1984-04-09 | 1985-11-12 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
US5104648A (en) * | 1989-02-02 | 1992-04-14 | Mallinckrodt Specialty Chemicals Company | High ibuprofen content granulations |
DE3927113C2 (de) * | 1989-08-17 | 1993-11-25 | Dolorgiet Gmbh & Co Kg | Mittel zur Behandlung von schweren Schmerzzuständen und Verfahren zu ihrer Herstellung |
US6165500A (en) | 1990-08-24 | 2000-12-26 | Idea Ag | Preparation for the application of agents in mini-droplets |
JP3765579B2 (ja) * | 1990-08-24 | 2006-04-12 | イーデーエーアー アーゲー | 作用物質投与用超微小滴状調剤 |
US5512300A (en) * | 1992-09-15 | 1996-04-30 | Warner-Lambert Company | Prevention of ibuprofen from forming low melting eutectics with other therapeutic agents in solid dosage forms |
US5431916A (en) * | 1993-04-29 | 1995-07-11 | The Procter & Gamble Company | Pharmaceutical compositions and process of manufacture thereof |
JPH08325145A (ja) * | 1995-05-26 | 1996-12-10 | Sumitomo Pharmaceut Co Ltd | 安定なイソプロピルアンチピリン含有製剤 |
US6007843A (en) * | 1995-09-29 | 1999-12-28 | Lam Pharmaceuticals Corp. | Sustained release delivery system |
WO1997011681A1 (en) * | 1995-09-29 | 1997-04-03 | Lam Pharmaceuticals Inc. | Sustained release delivery system and long acting narcotic analgesics and antagonists |
AUPN814496A0 (en) * | 1996-02-19 | 1996-03-14 | Monash University | Dermal penetration enhancer |
JP4305685B2 (ja) * | 1998-04-23 | 2009-07-29 | 日本食品化工株式会社 | カルシウム吸収促進剤 |
US6183779B1 (en) * | 1999-03-22 | 2001-02-06 | Pharmascience Inc. | Stabilized pharmaceutical composition of a nonsteroidal anti-inflammatory agent and a prostaglandin |
US6251426B1 (en) * | 1999-09-02 | 2001-06-26 | Banner Pharmacaps, Inc. | Ibuprofen-containing softgels |
US20020177626A1 (en) * | 2001-01-19 | 2002-11-28 | Cook Graham D. | Treatment of sleep disturbances |
-
2002
- 2002-01-17 US US10/046,727 patent/US20020177626A1/en not_active Abandoned
- 2002-01-18 WO PCT/US2002/003855 patent/WO2002056877A1/en active IP Right Grant
- 2002-01-18 JP JP2002557385A patent/JP4402882B2/ja not_active Expired - Lifetime
- 2002-01-18 DK DK02720944T patent/DK1363608T3/da active
- 2002-01-18 CA CA2434484A patent/CA2434484C/en not_active Expired - Lifetime
- 2002-01-18 EP EP02720944A patent/EP1363608B1/de not_active Expired - Lifetime
- 2002-01-18 DE DE60207383T patent/DE60207383T2/de not_active Expired - Lifetime
- 2002-01-18 AT AT02720944T patent/ATE309797T1/de active
- 2002-01-18 MX MXPA03006364A patent/MXPA03006364A/es active IP Right Grant
- 2002-01-18 ES ES02720944T patent/ES2251584T3/es not_active Expired - Lifetime
-
2004
- 2004-04-20 HK HK04102765A patent/HK1060045A1/xx not_active IP Right Cessation
-
2008
- 2008-04-10 US US12/082,342 patent/US8263647B2/en not_active Expired - Lifetime
-
2009
- 2009-06-17 JP JP2009144498A patent/JP2009203243A/ja active Pending
-
2012
- 2012-08-13 US US13/584,054 patent/US8883849B2/en not_active Expired - Lifetime
-
2014
- 2014-10-01 US US14/504,159 patent/US9155718B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20020177626A1 (en) | 2002-11-28 |
JP4402882B2 (ja) | 2010-01-20 |
CA2434484C (en) | 2011-08-09 |
US8883849B2 (en) | 2014-11-11 |
US8263647B2 (en) | 2012-09-11 |
US20090169584A1 (en) | 2009-07-02 |
DE60207383T2 (de) | 2006-08-03 |
DK1363608T3 (da) | 2006-02-13 |
US20120308483A1 (en) | 2012-12-06 |
JP2004521104A (ja) | 2004-07-15 |
ATE309797T1 (de) | 2005-12-15 |
US20150018421A1 (en) | 2015-01-15 |
HK1060045A1 (en) | 2004-07-30 |
EP1363608A1 (de) | 2003-11-26 |
CA2434484A1 (en) | 2002-07-25 |
WO2002056877A1 (en) | 2002-07-25 |
US9155718B2 (en) | 2015-10-13 |
MXPA03006364A (es) | 2003-10-06 |
EP1363608B1 (de) | 2005-11-16 |
ES2251584T3 (es) | 2006-05-01 |
JP2009203243A (ja) | 2009-09-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60207383D1 (de) | Ibuprofen und diphenhydramin enthaltende zusammensetzungen und deren verwendung zur behandlung von schlafstörungen | |
EA200801492A1 (ru) | Фармацевтическое применение замещенных амидов | |
EA200801243A1 (ru) | Фармацевтическое применение замещенных амидов | |
DE69428791D1 (de) | Verwendung vonModafinil zur Behandlung von Atemstillstand im Schlaf und zentral erregten Atembeschwerden | |
ATE467616T1 (de) | Verbindungen mit aktivität an der 11beta- hydroxasteroiddehydrogenase | |
DK0725779T3 (da) | Hidtil ukendte (R)-5-Carbamoyl-8-fluor-3-N,N-disubstitueret-amino-3,4-dihydro-2H-1-benzopyraner | |
DE69507029T2 (de) | Pharmazeutische zusammensetzungen enthaltend einen opiat antagonist und calcium salze, ihre verwendung zur behandlung von endorphin-vermittelten krankheiten | |
DE59409312D1 (de) | Imidazopyridine und ihre anwendung zur behandlung von magen-darm krankheiten | |
ATE242003T1 (de) | Enzyme zur behandlung von diabetes mellitus typ i | |
DE69906671D1 (de) | Substituierte 2-Phenyl-1-(3,4-dihydroxy-5-nitrophenyl)-1-ethanone, deren Verwendung zur Behandlung von Erkrankungen des zentralen und periphären Nervensystems und diese enthaltende pharmazeutische Zusammensetzungen | |
ATE177421T1 (de) | Wasserlösliches nimesulid-salz, sowie dessen verwendung zur behandlung von entzündungen | |
ATE238792T1 (de) | Verwendung von makroliden zur behandlung von glaukom | |
ATE446285T1 (de) | Für die behandlung von alzheimer-krankheit und ähnlichen leiden geeignete 1-alkyl-3- thiosubstituierte indol-2-alkinsäuren | |
NO982989L (no) | Anvendelse av inhibitorer av den cellulµre Na+/H+-utbytteren (NHE) for fremstilling av et medikament for respiratorstimulering | |
DE602004031631D1 (de) | Verwendung von betain zur behandlung von claudicatio intermittens | |
DE60018704D1 (de) | Bretyliumhaltige zusammensetzungen und kits und deren verwendung zur vorbeugung und behandlung cardiovaskulärer erkrankungen | |
FI974444A (fi) | N-hydroksiureayhdisteitä anti-inflammatorisina aineina | |
DE60027127D1 (de) | Verwendung von Polyaminosäurederivaten zur Behandlung von Seborrhoe und verwandten Hautstörungen | |
ATE216891T1 (de) | Verwendung von immunosuppressiva zur behandlung der schizophrenie | |
ATE232541T1 (de) | Gallensauersälze mit physiologisch aktiven metalle und ihre verwendung zur therapeutischen behandlung | |
MXPA04006457A (es) | Alcanosulfonamidas novedosas como antagonistas de endotelina. | |
DE60313785D1 (de) | Kombinierte verwendung von melatonin und methylphenidat zur behandlung von aufmerksamkeits-/hyperaktivitätsstörungen. | |
DE60121978D1 (de) | 7-CHLOR-4-HYDROXY-2-(2-PYRIDYLETHYL)-1,2,5,10-TETRAHYDROPYRIDAZINOi4,5-BöCHINOLIN-1,10-DIONE UND IHRE VERWENDUNG ZUR BEHANDLUNG VON SCHMERZEN | |
ATE469146T1 (de) | Benzofuranderivate und deren verwendung bei der behandlung von mikrobiellen infektionen | |
DE60113895D1 (de) | Verwendung von Tiludronsäure beim Geflügel zur Herstellung eines Arzneimittels zur Prophylaxe und Behandlung von Osteoporose |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |