DE69428791D1 - Verwendung vonModafinil zur Behandlung von Atemstillstand im Schlaf und zentral erregten Atembeschwerden - Google Patents
Verwendung vonModafinil zur Behandlung von Atemstillstand im Schlaf und zentral erregten AtembeschwerdenInfo
- Publication number
- DE69428791D1 DE69428791D1 DE69428791T DE69428791T DE69428791D1 DE 69428791 D1 DE69428791 D1 DE 69428791D1 DE 69428791 T DE69428791 T DE 69428791T DE 69428791 T DE69428791 T DE 69428791T DE 69428791 D1 DE69428791 D1 DE 69428791D1
- Authority
- DE
- Germany
- Prior art keywords
- modafinil
- treatment
- sleep apnea
- pct
- breathing difficulties
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- YFGHCGITMMYXAQ-UHFFFAOYSA-N 2-[(diphenylmethyl)sulfinyl]acetamide Chemical compound C=1C=CC=CC=1C(S(=O)CC(=O)N)C1=CC=CC=C1 YFGHCGITMMYXAQ-UHFFFAOYSA-N 0.000 title abstract 2
- 229960001165 modafinil Drugs 0.000 title abstract 2
- 201000002859 sleep apnea Diseases 0.000 title abstract 2
- 230000029058 respiratory gaseous exchange Effects 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 238000009423 ventilation Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9307555A FR2706767B1 (de) | 1993-06-22 | 1993-06-22 | |
PCT/FR1994/000711 WO1995000132A1 (fr) | 1993-06-22 | 1994-06-14 | Utilisation du modafinil pour le traitement des apnees du sommeil et troubles ventilatoires d'origine centrale |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69428791D1 true DE69428791D1 (de) | 2001-11-29 |
DE69428791T2 DE69428791T2 (de) | 2002-07-04 |
Family
ID=9448411
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69428791T Expired - Lifetime DE69428791T2 (de) | 1993-06-22 | 1994-06-14 | Verwendung vonModafinil zur Behandlung von Atemstillstand im Schlaf und zentral erregten Atembeschwerden |
Country Status (14)
Country | Link |
---|---|
US (1) | US5612379A (de) |
EP (1) | EP0705099B1 (de) |
JP (1) | JP3703831B2 (de) |
KR (1) | KR100315389B1 (de) |
AT (1) | ATE207351T1 (de) |
AU (1) | AU684087B2 (de) |
CA (1) | CA2165824C (de) |
DE (1) | DE69428791T2 (de) |
DK (1) | DK0705099T3 (de) |
ES (1) | ES2165878T3 (de) |
FR (1) | FR2706767B1 (de) |
HU (1) | HU216731B (de) |
PT (1) | PT705099E (de) |
WO (1) | WO1995000132A1 (de) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5618845A (en) * | 1994-10-06 | 1997-04-08 | Cephalon, Inc. | Acetamide derivative having defined particle size |
US20060241164A1 (en) * | 1998-02-27 | 2006-10-26 | The Board Of Trustees Of The University Of Illinoi | Pharmacological treatment for sleep apnea |
US7160898B2 (en) * | 2001-12-14 | 2007-01-09 | Board Of Trustees Of The University Of Illinois | Pharmacological treatment for sleep apnea |
WO1999043319A1 (en) | 1998-02-27 | 1999-09-02 | The Board Of Trustees Of The University Of Illinois | Agents with serotonin-related activity for the treatment for sleep apnea |
US6492396B2 (en) | 2000-05-16 | 2002-12-10 | Cephalon, Inc. | Substituted thioacetamides |
ATE417608T1 (de) * | 2000-10-11 | 2009-01-15 | Cephalon Inc | Arzneizusammensetzungen enthaltend modafinilverbindungen |
US20080058424A1 (en) * | 2002-05-23 | 2008-03-06 | Cephalon, Inc. | Novel pharmaceutical formulations of modafinil |
MXPA03010705A (es) * | 2001-05-25 | 2004-05-27 | Cephalon Inc | Formulaciones farmaceuticas solidas que comprenden modafinil. |
US7229644B2 (en) * | 2002-05-23 | 2007-06-12 | Cephalon, Inc. | Pharmaceutical formulations of modafinil |
US20040048931A1 (en) | 2002-07-12 | 2004-03-11 | Craig Heacock | Modafinil pharmaceutical compositions |
US6992219B2 (en) | 2002-08-09 | 2006-01-31 | Cephalon France | Modafinil polymorphic forms |
US20040116532A1 (en) * | 2002-09-13 | 2004-06-17 | Craig Heacock | Pharmaceutical formulations of modafinil |
IL153098A0 (en) * | 2002-11-26 | 2003-06-24 | Chemagis Ltd | Pharmaceutical compositions containing modafinil |
US7528172B2 (en) * | 2003-01-21 | 2009-05-05 | The Cooper Health System, Inc. | Compositions and methods for improving recovery after general anesthesia |
CA2519117C (en) * | 2003-03-17 | 2010-03-02 | Neurohealing Pharmaceuticals, Inc. | High potency dopaminergic treatment of neurological impairment associated with brain injury |
US20040253308A1 (en) * | 2003-04-29 | 2004-12-16 | Barr Laboratories, Inc. | Surface-treated modafinil particles |
AR045423A1 (es) * | 2003-05-13 | 2005-10-26 | Cephalon Inc | Combinaciones de analiticos y antidepresivos |
US7368591B2 (en) | 2003-09-19 | 2008-05-06 | Cephalon France | Process for enantioselective synthesis of single enantiomers of modafinil by asymmetric oxidation |
EP1586560A1 (de) * | 2004-04-13 | 2005-10-19 | Cephalon, Inc. | Thio-substituierte Arylmethansulfinyl-Derivate |
US7423176B2 (en) * | 2004-04-13 | 2008-09-09 | Cephalon, Inc. | Bicyclic aromatic sulfinyl derivatives |
US7297817B2 (en) * | 2004-04-13 | 2007-11-20 | Cephalon France | Thio-substituted arylmethanesulfinyl derivatives |
US7314875B2 (en) * | 2004-04-13 | 2008-01-01 | Cephalon, Inc. | Tricyclic aromatic and bis-phenyl sulfinyl derivatives |
US7119214B2 (en) * | 2004-04-13 | 2006-10-10 | Cephalon France | Thio-substituted tricyclic and bicyclic aromatic methanesulfinyl derivatives |
US7449481B2 (en) * | 2004-04-13 | 2008-11-11 | Cephalon, Inc. | Thio-substituted biaryl-methanesulfinyl derivatives |
EP1833467B1 (de) * | 2004-12-20 | 2016-08-03 | Collegium Pharmaceutical, Inc. | Pharmazeutische zusammensetzungen gegen schlafstörungen |
CA2614777C (en) * | 2005-07-21 | 2012-04-17 | Neurohealing Pharmaceuticals, Inc. | Rapid onset and short term modafinil compositions and methods of use thereof |
KR20090031618A (ko) * | 2006-07-12 | 2009-03-26 | 엘란 코포레이션, 피엘씨 | 나노입자형 모다피닐 제제 |
CA2660565C (en) * | 2006-08-14 | 2012-10-09 | Neurohealing Pharmaceuticals, Inc. | Modafinil-based treatment for premature ejaculation |
US20080181966A1 (en) * | 2006-10-18 | 2008-07-31 | Cephalon, Inc. | Modafinil pharmaceutical compositions |
WO2008077127A2 (en) * | 2006-12-19 | 2008-06-26 | Lavin Thomas N | Use of modafinil to treat restless leg syndrome |
KR20120101588A (ko) * | 2010-01-07 | 2012-09-13 | 비버스 인크. | 탄산탈수효소 억제제 및 추가적인 활성제의 조합에 의한 폐쇄 수면 무호흡 증후군의 치료 |
EP3040078B1 (de) | 2013-08-30 | 2021-02-24 | Green Cross Wellbeing Corporation | Zusammensetzung zur vorbeugung und behandlung von krebsbedingter fatigue mit verarbeitetem ginseng-pulver oder verarbeitetem ginseng-extrakt mit erhöhtem gehalt des bestandteils ginsenosid |
US9616068B2 (en) | 2014-10-27 | 2017-04-11 | Pohela LLC | Animal training using cognitive enhancement |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1584462A (en) * | 1977-03-31 | 1981-02-11 | Lafon Labor | N-diaryl-malonamide and diarylmethyl-sulphinyl-acetamide derivatives and pharmaceutical compositions containing them |
FR2663225B1 (fr) * | 1990-06-14 | 1994-11-04 | Lafon Labor | Nouvelle utilisation du modafinil. |
FR2684875B1 (fr) * | 1991-12-13 | 1995-05-24 | Lafon Labor | Utilisation du modafinil pour la fabrication d'un medicament ayant un effet anti-ischemique. |
US5281607B1 (en) * | 1992-10-08 | 1998-05-19 | Univ New York | Method of using alpha 2-antagonists for the treatment of neurodegenerative diseases |
-
1993
- 1993-06-22 FR FR9307555A patent/FR2706767B1/fr not_active Expired - Fee Related
-
1994
- 1994-06-14 EP EP94919708A patent/EP0705099B1/de not_active Expired - Lifetime
- 1994-06-14 AU AU70760/94A patent/AU684087B2/en not_active Expired
- 1994-06-14 ES ES94919708T patent/ES2165878T3/es not_active Expired - Lifetime
- 1994-06-14 AT AT94919708T patent/ATE207351T1/de active
- 1994-06-14 DE DE69428791T patent/DE69428791T2/de not_active Expired - Lifetime
- 1994-06-14 CA CA002165824A patent/CA2165824C/fr not_active Expired - Lifetime
- 1994-06-14 DK DK94919708T patent/DK0705099T3/da active
- 1994-06-14 US US08/564,286 patent/US5612379A/en not_active Expired - Lifetime
- 1994-06-14 KR KR1019950705833A patent/KR100315389B1/ko not_active IP Right Cessation
- 1994-06-14 PT PT94919708T patent/PT705099E/pt unknown
- 1994-06-14 JP JP50249895A patent/JP3703831B2/ja not_active Expired - Lifetime
- 1994-06-14 HU HU9503702A patent/HU216731B/hu unknown
- 1994-06-14 WO PCT/FR1994/000711 patent/WO1995000132A1/fr active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EP0705099A1 (de) | 1996-04-10 |
HU9503702D0 (en) | 1996-02-28 |
JP3703831B2 (ja) | 2005-10-05 |
US5612379A (en) | 1997-03-18 |
HU216731B (hu) | 1999-08-30 |
EP0705099B1 (de) | 2001-10-24 |
KR960703009A (ko) | 1996-06-19 |
AU684087B2 (en) | 1997-12-04 |
WO1995000132A1 (fr) | 1995-01-05 |
AU7076094A (en) | 1995-01-17 |
KR100315389B1 (ko) | 2002-02-19 |
PT705099E (pt) | 2002-03-28 |
JPH09500374A (ja) | 1997-01-14 |
ATE207351T1 (de) | 2001-11-15 |
DK0705099T3 (da) | 2002-02-11 |
DE69428791T2 (de) | 2002-07-04 |
HUT74674A (en) | 1997-01-28 |
CA2165824A1 (fr) | 1995-01-05 |
ES2165878T3 (es) | 2002-04-01 |
CA2165824C (fr) | 2005-08-02 |
FR2706767B1 (de) | 1995-09-08 |
FR2706767A1 (de) | 1994-12-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |