BR0309969A - Uso de compostos que são eficazes como moduladores de receptores seletivos de opiáceos - Google Patents

Uso de compostos que são eficazes como moduladores de receptores seletivos de opiáceos

Info

Publication number
BR0309969A
BR0309969A BR0309969-5A BR0309969A BR0309969A BR 0309969 A BR0309969 A BR 0309969A BR 0309969 A BR0309969 A BR 0309969A BR 0309969 A BR0309969 A BR 0309969A
Authority
BR
Brazil
Prior art keywords
effective
compounds
disorders
opioid receptor
receptor modulators
Prior art date
Application number
BR0309969-5A
Other languages
English (en)
Inventor
Frank Weber
Jutta Jacob
Andrew Barber
Rudolf Gottschlich
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of BR0309969A publication Critical patent/BR0309969A/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

"USO DE COMPOSTOS QUE SãO EFICAZES COMO MODULADORES DE RECEPTORES SELETIVOS DE OPIáCEOS". A presente invenção refere-se ao uso de compostos que são eficazes como moduladores de receptores seletivos de opiáceos, para a fabricação de produtos farmacêuticos para o diagnóstico e/ou tratamento de distúrbios, sendo os ditos distúrbios selecionados entre distúrbios alimentares e distúrbios digestivos, especialmente distúrbios alimentares psicogênicos, para a fabricação de um produto farmacêutico eficaz para modular o tónus gastrointestinal, e uma composição farmacêutica que compreende um ou mais dos ditos compostos moduladores e um ou mais compostos que são eficazes como depressor do apetite.
BR0309969-5A 2002-05-17 2003-04-28 Uso de compostos que são eficazes como moduladores de receptores seletivos de opiáceos BR0309969A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02011047 2002-05-17
PCT/EP2003/004428 WO2003097051A2 (en) 2002-05-17 2003-04-28 Use of compounds that are effective as selective opiate receptor modulators

Publications (1)

Publication Number Publication Date
BR0309969A true BR0309969A (pt) 2005-04-26

Family

ID=29433078

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0309969-5A BR0309969A (pt) 2002-05-17 2003-04-28 Uso de compostos que são eficazes como moduladores de receptores seletivos de opiáceos

Country Status (21)

Country Link
US (1) US20050176746A1 (pt)
EP (2) EP1505974B1 (pt)
JP (1) JP2005531557A (pt)
KR (1) KR101108014B1 (pt)
CN (2) CN101310723A (pt)
AR (1) AR040028A1 (pt)
AT (1) ATE429226T1 (pt)
AU (1) AU2003242527B2 (pt)
BR (1) BR0309969A (pt)
CA (1) CA2486000A1 (pt)
DE (1) DE60327315D1 (pt)
DK (1) DK1505974T3 (pt)
ES (1) ES2325782T3 (pt)
HK (1) HK1079451A1 (pt)
MX (1) MXPA04011333A (pt)
PE (1) PE20040455A1 (pt)
PL (1) PL371596A1 (pt)
RU (1) RU2336871C2 (pt)
TW (1) TWI314053B (pt)
WO (1) WO2003097051A2 (pt)
ZA (1) ZA200410160B (pt)

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US10376481B2 (en) 2012-08-21 2019-08-13 Ardelyx, Inc. Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
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Also Published As

Publication number Publication date
EP1505974A2 (en) 2005-02-16
ATE429226T1 (de) 2009-05-15
DK1505974T3 (da) 2009-08-17
TW200307541A (en) 2003-12-16
EP1505974B1 (en) 2009-04-22
AU2003242527A1 (en) 2003-12-02
KR101108014B1 (ko) 2012-01-25
KR20050010807A (ko) 2005-01-28
PE20040455A1 (es) 2004-08-07
AU2003242527B2 (en) 2008-10-23
JP2005531557A (ja) 2005-10-20
ZA200410160B (en) 2005-12-28
MXPA04011333A (es) 2005-02-14
CN1655784A (zh) 2005-08-17
CA2486000A1 (en) 2003-11-27
RU2004137091A (ru) 2005-09-10
PL371596A1 (en) 2005-06-27
CN100411618C (zh) 2008-08-20
AR040028A1 (es) 2005-03-09
HK1079451A1 (en) 2006-04-07
DE60327315D1 (de) 2009-06-04
ES2325782T3 (es) 2009-09-17
EP2074997A1 (en) 2009-07-01
WO2003097051A3 (en) 2004-12-09
CN101310723A (zh) 2008-11-26
TWI314053B (en) 2009-09-01
US20050176746A1 (en) 2005-08-11
RU2336871C2 (ru) 2008-10-27
WO2003097051A2 (en) 2003-11-27

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Owner name: TIOGA PHARMACEUTICALS, INC. (US)

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B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B11E Dismissal acc. art. 34 of ipl - requirements for examination incomplete
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