RU2314307C2 - СОЕДИНЕНИЕ, ВКЛЮЧАЮЩЕЕ 2-МЕТИЛ-1-(2-МЕТИЛПРОПИЛ)-1Н-ИМИДАЗО[4,5-c][1,5]НАФТИРИДИН-4-АМИН, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ЕГО ОСНОВЕ И СПОСОБ СТИМУЛЯЦИИ БИОСИНТЕЗА ЦИТОКИНА В ОРГАНИЗМЕ ЖИВОТНЫХ - Google Patents
СОЕДИНЕНИЕ, ВКЛЮЧАЮЩЕЕ 2-МЕТИЛ-1-(2-МЕТИЛПРОПИЛ)-1Н-ИМИДАЗО[4,5-c][1,5]НАФТИРИДИН-4-АМИН, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ЕГО ОСНОВЕ И СПОСОБ СТИМУЛЯЦИИ БИОСИНТЕЗА ЦИТОКИНА В ОРГАНИЗМЕ ЖИВОТНЫХ Download PDFInfo
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- RU2314307C2 RU2314307C2 RU2003126258/04A RU2003126258A RU2314307C2 RU 2314307 C2 RU2314307 C2 RU 2314307C2 RU 2003126258/04 A RU2003126258/04 A RU 2003126258/04A RU 2003126258 A RU2003126258 A RU 2003126258A RU 2314307 C2 RU2314307 C2 RU 2314307C2
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- Prior art keywords
- compound
- animal body
- imidazo
- methylpropyl
- amine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
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- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Engineering & Computer Science (AREA)
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- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
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- Rheumatology (AREA)
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- AIDS & HIV (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6927697P | 1997-12-11 | 1997-12-11 | |
US60/069.276 | 1997-12-11 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2000114496/04A Division RU2221798C2 (ru) | 1997-12-11 | 1998-12-11 | Имидазонафтиридины, фармацевтическая композиция на их основе, способ стимуляции биосинтеза цитокина и промежуточные вещества |
Publications (2)
Publication Number | Publication Date |
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RU2003126258A RU2003126258A (ru) | 2005-03-10 |
RU2314307C2 true RU2314307C2 (ru) | 2008-01-10 |
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ID=22087889
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2003126258/04A RU2314307C2 (ru) | 1997-12-11 | 1998-12-11 | СОЕДИНЕНИЕ, ВКЛЮЧАЮЩЕЕ 2-МЕТИЛ-1-(2-МЕТИЛПРОПИЛ)-1Н-ИМИДАЗО[4,5-c][1,5]НАФТИРИДИН-4-АМИН, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ЕГО ОСНОВЕ И СПОСОБ СТИМУЛЯЦИИ БИОСИНТЕЗА ЦИТОКИНА В ОРГАНИЗМЕ ЖИВОТНЫХ |
RU2000114496/04A RU2221798C2 (ru) | 1997-12-11 | 1998-12-11 | Имидазонафтиридины, фармацевтическая композиция на их основе, способ стимуляции биосинтеза цитокина и промежуточные вещества |
RU2003126259/04A RU2312867C2 (ru) | 1997-12-11 | 1998-12-11 | СОЕДИНЕНИЕ, ВКЛЮЧАЮЩЕЕ 1-(2-МЕТИЛПРОПИЛ)-1Н-ИМИДАЗО[4,5-с][1,5]НАФТИРИДИН-4-АМИН, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ЕГО ОСНОВЕ И СПОСОБ СТИМУЛЯЦИИ БИОСИНТЕЗА ЦИТОКИНА В ОРГАНИЗМЕ ЖИВОТНЫХ |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2000114496/04A RU2221798C2 (ru) | 1997-12-11 | 1998-12-11 | Имидазонафтиридины, фармацевтическая композиция на их основе, способ стимуляции биосинтеза цитокина и промежуточные вещества |
RU2003126259/04A RU2312867C2 (ru) | 1997-12-11 | 1998-12-11 | СОЕДИНЕНИЕ, ВКЛЮЧАЮЩЕЕ 1-(2-МЕТИЛПРОПИЛ)-1Н-ИМИДАЗО[4,5-с][1,5]НАФТИРИДИН-4-АМИН, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ЕГО ОСНОВЕ И СПОСОБ СТИМУЛЯЦИИ БИОСИНТЕЗА ЦИТОКИНА В ОРГАНИЗМЕ ЖИВОТНЫХ |
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Families Citing this family (223)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5741908A (en) | 1996-06-21 | 1998-04-21 | Minnesota Mining And Manufacturing Company | Process for reparing imidazoquinolinamines |
UA67760C2 (uk) | 1997-12-11 | 2004-07-15 | Міннесота Майнінг Енд Мануфакчурінг Компані | Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки |
US6518280B2 (en) | 1998-12-11 | 2003-02-11 | 3M Innovative Properties Company | Imidazonaphthyridines |
EP1140091B1 (en) | 1999-01-08 | 2005-09-21 | 3M Innovative Properties Company | Formulations comprising imiquimod or other immune response modifiers for treating cervical dysplasia |
US20020058674A1 (en) | 1999-01-08 | 2002-05-16 | Hedenstrom John C. | Systems and methods for treating a mucosal surface |
US6486168B1 (en) | 1999-01-08 | 2002-11-26 | 3M Innovative Properties Company | Formulations and methods for treatment of mucosal associated conditions with an immune response modifier |
US6558951B1 (en) * | 1999-02-11 | 2003-05-06 | 3M Innovative Properties Company | Maturation of dendritic cells with immune response modifying compounds |
SI1198233T1 (sl) * | 1999-06-10 | 2007-02-28 | 3M Innovative Properties Co | S sulfonamidom in sulfamidom substituirani imidazokinolini |
US6451810B1 (en) * | 1999-06-10 | 2002-09-17 | 3M Innovative Properties Company | Amide substituted imidazoquinolines |
US6756382B2 (en) * | 1999-06-10 | 2004-06-29 | 3M Innovative Properties Company | Amide substituted imidazoquinolines |
US6331539B1 (en) | 1999-06-10 | 2001-12-18 | 3M Innovative Properties Company | Sulfonamide and sulfamide substituted imidazoquinolines |
US6541485B1 (en) | 1999-06-10 | 2003-04-01 | 3M Innovative Properties Company | Urea substituted imidazoquinolines |
EP1438958A1 (en) * | 1999-06-10 | 2004-07-21 | 3M Innovative Properties Company | Carbamate substituted imidazoquinolines |
US6573273B1 (en) | 1999-06-10 | 2003-06-03 | 3M Innovative Properties Company | Urea substituted imidazoquinolines |
US6916925B1 (en) | 1999-11-05 | 2005-07-12 | 3M Innovative Properties Co. | Dye labeled imidazoquinoline compounds |
US6376669B1 (en) | 1999-11-05 | 2002-04-23 | 3M Innovative Properties Company | Dye labeled imidazoquinoline compounds |
JP3436512B2 (ja) * | 1999-12-28 | 2003-08-11 | 株式会社デンソー | アクセル装置 |
US6894060B2 (en) | 2000-03-30 | 2005-05-17 | 3M Innovative Properties Company | Method for the treatment of dermal lesions caused by envenomation |
US20040209877A1 (en) * | 2000-04-13 | 2004-10-21 | Shelby Nancy J. | Methods for augmenting immune defenses contemplating the administration of phenolic and indoleamine-like compounds for use in animals ans humans |
UA74593C2 (en) * | 2000-12-08 | 2006-01-16 | 3M Innovative Properties Co | Substituted imidazopyridines |
US6667312B2 (en) * | 2000-12-08 | 2003-12-23 | 3M Innovative Properties Company | Thioether substituted imidazoquinolines |
AU2006216669A1 (en) * | 2000-12-08 | 2006-08-31 | 3M Innovative Properties Company | Compositions and methods for targeted delivery of immune response modifiers |
US6545017B1 (en) * | 2000-12-08 | 2003-04-08 | 3M Innovative Properties Company | Urea substituted imidazopyridines |
US6664264B2 (en) * | 2000-12-08 | 2003-12-16 | 3M Innovative Properties Company | Thioether substituted imidazoquinolines |
US6545016B1 (en) * | 2000-12-08 | 2003-04-08 | 3M Innovative Properties Company | Amide substituted imidazopyridines |
US6660747B2 (en) | 2000-12-08 | 2003-12-09 | 3M Innovative Properties Company | Amido ether substituted imidazoquinolines |
US6677348B2 (en) | 2000-12-08 | 2004-01-13 | 3M Innovative Properties Company | Aryl ether substituted imidazoquinolines |
AU3249802A (en) * | 2000-12-08 | 2002-06-18 | 3M Innovative Properties Co | Screening method for identifying compounds that selectively induce interferon alpha |
US6677347B2 (en) * | 2000-12-08 | 2004-01-13 | 3M Innovative Properties Company | Sulfonamido ether substituted imidazoquinolines |
UA74852C2 (en) * | 2000-12-08 | 2006-02-15 | 3M Innovative Properties Co | Urea-substituted imidazoquinoline ethers |
US6525064B1 (en) | 2000-12-08 | 2003-02-25 | 3M Innovative Properties Company | Sulfonamido substituted imidazopyridines |
US6664260B2 (en) * | 2000-12-08 | 2003-12-16 | 3M Innovative Properties Company | Heterocyclic ether substituted imidazoquinolines |
US6664265B2 (en) | 2000-12-08 | 2003-12-16 | 3M Innovative Properties Company | Amido ether substituted imidazoquinolines |
US6660735B2 (en) * | 2000-12-08 | 2003-12-09 | 3M Innovative Properties Company | Urea substituted imidazoquinoline ethers |
US7226928B2 (en) * | 2001-06-15 | 2007-06-05 | 3M Innovative Properties Company | Methods for the treatment of periodontal disease |
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- 1998-12-11 EP EP98963888A patent/EP1040112B1/en not_active Expired - Lifetime
- 1998-12-11 JP JP2000524286A patent/JP4283438B2/ja not_active Expired - Fee Related
- 1998-12-11 CZ CZ2007-268A patent/CZ307184B6/cs not_active IP Right Cessation
- 1998-12-11 ES ES98963888T patent/ES2227902T3/es not_active Expired - Lifetime
- 1998-12-11 IL IL13655698A patent/IL136556A0/xx active IP Right Grant
- 1998-12-11 AT AT98963888T patent/ATE277046T1/de not_active IP Right Cessation
- 1998-12-11 RU RU2003126259/04A patent/RU2312867C2/ru not_active IP Right Cessation
- 1998-12-11 PT PT98963888T patent/PT1040112E/pt unknown
- 1998-12-11 TR TR2000/01705T patent/TR200001705T2/xx unknown
-
2000
- 2000-05-24 NO NO20002663A patent/NO316687B1/no not_active IP Right Cessation
- 2000-06-02 HR HR20000363A patent/HRP20000363B1/xx not_active IP Right Cessation
- 2000-06-05 IL IL136556A patent/IL136556A/en not_active IP Right Cessation
- 2000-11-06 US US09/706,990 patent/US6514985B1/en not_active Expired - Fee Related
-
2001
- 2001-08-31 US US09/945,197 patent/US6624172B2/en not_active Expired - Lifetime
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2002
- 2002-06-27 US US10/185,387 patent/US6693113B2/en not_active Expired - Lifetime
- 2002-06-27 US US10/184,304 patent/US6638944B2/en not_active Expired - Fee Related
- 2002-10-07 US US10/265,956 patent/US6699878B2/en not_active Expired - Fee Related
-
2003
- 2003-04-02 US US10/405,321 patent/US6747040B2/en not_active Expired - Fee Related
- 2003-04-03 US US10/406,181 patent/US6797716B2/en not_active Expired - Lifetime
- 2003-12-19 NO NO20035718A patent/NO328045B1/no not_active IP Right Cessation
- 2003-12-19 NO NO20035719A patent/NO20035719D0/no unknown
-
2004
- 2004-04-14 US US10/824,232 patent/US6894165B2/en not_active Expired - Fee Related
- 2004-12-03 US US11/004,674 patent/US6949646B2/en not_active Expired - Lifetime
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2005
- 2005-04-21 HK HK05103436A patent/HK1070655A1/xx not_active IP Right Cessation
- 2005-07-25 US US11/188,418 patent/US7038051B2/en not_active Expired - Lifetime
- 2005-12-12 JP JP2005358302A patent/JP4203067B2/ja not_active Expired - Fee Related
-
2006
- 2006-02-13 US US11/276,074 patent/US7335773B2/en not_active Expired - Fee Related
- 2006-09-14 IL IL178092A patent/IL178092A/en not_active IP Right Cessation
- 2006-09-14 IL IL178091A patent/IL178091A/en not_active IP Right Cessation
-
2007
- 2007-03-28 US US11/692,701 patent/US20070167481A1/en not_active Abandoned
- 2007-07-11 JP JP2007181872A patent/JP2007262093A/ja not_active Withdrawn
- 2007-12-06 US US11/999,602 patent/US7678918B2/en not_active Expired - Fee Related
- 2007-12-26 JP JP2007335120A patent/JP2008115190A/ja active Pending
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