BR9911756A - Composto, uso de um secretagogo do hormÈnio do crescimento ou um seu sal farmaceuticamente aceitável, composição farmacêutica, método para estimular a liberação do hormÈnio do crescimento pela pituitária de um mamìfero, e, uso de um composto - Google Patents

Composto, uso de um secretagogo do hormÈnio do crescimento ou um seu sal farmaceuticamente aceitável, composição farmacêutica, método para estimular a liberação do hormÈnio do crescimento pela pituitária de um mamìfero, e, uso de um composto

Info

Publication number
BR9911756A
BR9911756A BR9911756-8A BR9911756A BR9911756A BR 9911756 A BR9911756 A BR 9911756A BR 9911756 A BR9911756 A BR 9911756A BR 9911756 A BR9911756 A BR 9911756A
Authority
BR
Brazil
Prior art keywords
growth hormone
compound
pituitary
release
pharmaceutically acceptable
Prior art date
Application number
BR9911756-8A
Other languages
English (en)
Other versions
BRPI9911756B1 (pt
Inventor
Bernd Peschke
Stefan Lutz Richter
Thomas Kruse Hansen
Michael Ankersen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of BR9911756A publication Critical patent/BR9911756A/pt
Publication of BRPI9911756B1 publication Critical patent/BRPI9911756B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

"COMPOSTO, USO DE UM SECRETAGOGO DO HORMÈNIO DO CRESCIMENTO OU UM SEU SAL FARMACEUTICAMENTE ACEITáVEL, COMPOSIçãO FARMACêUTICA, MéTODO PARA ESTIMULAR A LIBERAçãO DO HORMÈNIO DO CRESCIMENTO PELA PITUITáRIA DE UM MAMìFERO, E, USO DE UM COMPOSTO" A invenção refere-se a novos compostos, composições contendo-os e a seu uso para tratar distúrbios médicos resultantes de uma deficiência do hormónio do crescimento.
BRPI9911756A 1998-06-30 1999-06-29 composto, uso do mesmo, e composição farmaceutica BRPI9911756B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA199800857 1998-06-30
DKPA199801440 1998-11-09
PCT/DK1999/000368 WO2000001726A1 (en) 1998-06-30 1999-06-29 Compounds with growth hormone releasing properties

Publications (2)

Publication Number Publication Date
BR9911756A true BR9911756A (pt) 2001-04-03
BRPI9911756B1 BRPI9911756B1 (pt) 2016-06-14

Family

ID=26064788

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9911756A BRPI9911756B1 (pt) 1998-06-30 1999-06-29 composto, uso do mesmo, e composição farmaceutica

Country Status (20)

Country Link
EP (1) EP1100824B1 (pt)
JP (1) JP4511040B2 (pt)
KR (1) KR100907638B1 (pt)
CN (1) CN1304424C (pt)
AT (1) ATE500269T1 (pt)
AU (1) AU771644B2 (pt)
BR (1) BRPI9911756B1 (pt)
CA (1) CA2334315C (pt)
CY (1) CY1111509T1 (pt)
CZ (1) CZ299648B6 (pt)
DE (1) DE69943239D1 (pt)
DK (1) DK1100824T3 (pt)
HU (1) HUP0102460A3 (pt)
IL (1) IL140044A0 (pt)
NO (1) NO331351B1 (pt)
PL (1) PL199853B1 (pt)
PT (1) PT1100824E (pt)
RU (1) RU2298547C2 (pt)
TW (1) TW593337B (pt)
WO (1) WO2000001726A1 (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003013571A1 (en) * 2001-08-10 2003-02-20 Palatin Technologies, Inc. Peptidomimetics of biologically active metallopeptides
US7476653B2 (en) 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
JP2007531769A (ja) * 2004-03-30 2007-11-08 サファイア セラピューティクス インコーポレイテッド 成長ホルモン分泌促進薬を使用したｃ−反応性蛋白質の低減方法
AU2005272598B2 (en) * 2004-08-12 2011-11-17 Helsinn Therapeutics (U.S.), Inc. Method of stimulating the motility of the gastrointestinal system using growth hormone secretagogues
US7772177B2 (en) 2005-05-18 2010-08-10 Aegera Therapeutics, Inc. BIR domain binding compounds
JP2009512719A (ja) 2005-10-25 2009-03-26 アエゲラ セラピューティクス インコーポレイテッド Ｉａｐｂｉｒドメイン結合化合物
CU23558A1 (es) 2006-02-28 2010-07-20 Ct Ingenieria Genetica Biotech Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento
ES2602789T3 (es) 2007-02-09 2017-02-22 Ocera Therapeutics, Inc. Productos intermedios conectores para la síntesis de moduladores macrocíclicos del receptor de la grelina
CN107382827B (zh) * 2017-04-14 2021-01-01 江苏普莱医药生物技术有限公司 氨基酸衍生物或其药学上可接受的盐及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994013696A1 (en) * 1992-12-11 1994-06-23 Merck & Co., Inc. Spiro piperidines and homologs which promote release of growth hormone
BR9608909A (pt) * 1995-06-22 1999-03-02 Novo Nordisk As Composto composição farmacêutica processos para estimular a liberação do hormônio do crescimento da patuitária e aumentar a velocidade e extensão do crescimento dos animais para aumentar a produção de leite ou lã de animais ou para para doenças e uso do composto
CZ195098A3 (cs) * 1995-12-22 1998-10-14 Novo Nordisk A/S Sloučeniny uvolňující růstový hormon
US5922770A (en) * 1996-07-22 1999-07-13 Novo Nordisk A/S Compounds with growth hormone releasing properties
WO1998058950A1 (en) * 1997-06-20 1998-12-30 Novo Nordisk A/S Compounds with growth hormone releasing properties

Also Published As

Publication number Publication date
JP4511040B2 (ja) 2010-07-28
KR100907638B1 (ko) 2009-07-14
EP1100824B1 (en) 2011-03-02
ATE500269T1 (de) 2011-03-15
DE69943239D1 (de) 2011-04-14
NO331351B1 (no) 2011-12-05
RU2298547C2 (ru) 2007-05-10
CZ299648B6 (cs) 2008-10-01
NO20006699L (no) 2001-02-28
CN1307588A (zh) 2001-08-08
BRPI9911756B1 (pt) 2016-06-14
DK1100824T3 (da) 2011-06-20
HUP0102460A2 (hu) 2001-11-28
WO2000001726A1 (en) 2000-01-13
TW593337B (en) 2004-06-21
IL140044A0 (en) 2002-02-10
HUP0102460A3 (en) 2001-12-28
AU4603899A (en) 2000-01-24
NO20006699D0 (no) 2000-12-29
CY1111509T1 (el) 2015-08-05
CA2334315C (en) 2011-07-26
KR20010053310A (ko) 2001-06-25
CZ20004565A3 (en) 2001-06-13
JP2002519436A (ja) 2002-07-02
PT1100824E (pt) 2011-06-16
EP1100824A1 (en) 2001-05-23
PL199853B1 (pl) 2008-11-28
CN1304424C (zh) 2007-03-14
CA2334315A1 (en) 2000-01-13
PL345204A1 (en) 2001-12-03
AU771644B2 (en) 2004-04-01

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B08G Application fees: restoration [chapter 8.7 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B25A Requested transfer of rights approved

Owner name: HELSINN HEALTHCARE SA (CH)

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

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B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

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B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2594 DE 24-09-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.