MX9705710A - Compuestos con propiedades de liberacion de la hormona del crecimiento. - Google Patents
Compuestos con propiedades de liberacion de la hormona del crecimiento.Info
- Publication number
- MX9705710A MX9705710A MX9705710A MX9705710A MX9705710A MX 9705710 A MX9705710 A MX 9705710A MX 9705710 A MX9705710 A MX 9705710A MX 9705710 A MX9705710 A MX 9705710A MX 9705710 A MX9705710 A MX 9705710A
- Authority
- MX
- Mexico
- Prior art keywords
- compounds
- growth hormone
- formula
- hormone releasing
- releasing properties
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/38—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/22—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/32—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/36—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having the nitrogen atom of the carboxamide group bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
- C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
- C07D271/10—1,3,4-Oxadiazoles; Hydrogenated 1,3,4-oxadiazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth-hormone releasing factors (GH-RF) (Somatoliberin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Esto revela nuevas síntesis de péptidos de formula general (I), donde las abreviaciones A,B,D,E,F,G, y m,n,p, y otros como se definio en la descripcion. Los compuestos de formula (I) promueven la liberacion de la hormona del crecimiento en humanos y animales. El crecimiento promueve composiciones que contienen tales compuestos de formula (I) como el ingrediente activo de esto, métodos de estimulacion de liberacion de la hormona del crecimiento como bien como uso de tales compuestos de formula (I) son también revelados.
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK9995 | 1995-01-27 | ||
DK10095 | 1995-01-27 | ||
DK108395 | 1995-09-28 | ||
DK108495 | 1995-09-28 | ||
DK137295 | 1995-12-04 | ||
PCT/DK1996/000045 WO1996022997A1 (en) | 1995-01-27 | 1996-01-26 | Compounds with growth hormone releasing properties |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9705710A true MX9705710A (es) | 1997-10-31 |
Family
ID=27512745
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9705710A MX9705710A (es) | 1995-01-27 | 1996-01-26 | Compuestos con propiedades de liberacion de la hormona del crecimiento. |
Country Status (20)
Country | Link |
---|---|
US (2) | US6013658A (es) |
EP (1) | EP0805816B1 (es) |
JP (1) | JP4073952B2 (es) |
CN (1) | CN1225471C (es) |
AR (1) | AR003108A1 (es) |
AT (1) | ATE272069T1 (es) |
AU (1) | AU705744B2 (es) |
CA (1) | CA2211381C (es) |
CZ (1) | CZ238197A3 (es) |
DE (1) | DE69633003T2 (es) |
HU (1) | HUP9702388A3 (es) |
ID (1) | ID18218A (es) |
IL (1) | IL116923A (es) |
MX (1) | MX9705710A (es) |
MY (1) | MY113488A (es) |
NO (1) | NO973446L (es) |
PL (1) | PL186511B1 (es) |
TW (1) | TW482767B (es) |
UA (1) | UA55381C2 (es) |
WO (1) | WO1996022997A1 (es) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5798337A (en) * | 1994-11-16 | 1998-08-25 | Genentech, Inc. | Low molecular weight peptidomimetic growth hormone secretagogues |
US20020111461A1 (en) | 1999-05-21 | 2002-08-15 | Todd C. Somers | Low molecular weight peptidomimetic growth hormone secretagogues |
ID18218A (id) | 1995-01-27 | 1998-03-19 | Novo Nordisk As | Senyawa dengan sifat-sifat pelepas hormon pertumbuhan |
ES2323159T3 (es) * | 1995-12-22 | 2009-07-07 | Novo Nordisk A/S | Compuestos con propiedades de liberacion de la hormona del crecimiento. |
TW432073B (en) * | 1995-12-28 | 2001-05-01 | Pfizer | Pyrazolopyridine compounds |
US6451970B1 (en) | 1996-02-21 | 2002-09-17 | Novo Nordisk A/S | Peptide derivatives |
EP0923539B1 (en) | 1996-07-22 | 2002-06-05 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
US6127341A (en) * | 1997-06-20 | 2000-10-03 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
AU7906998A (en) | 1997-06-20 | 1999-01-04 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
BR9906975A (pt) | 1998-01-16 | 2000-10-17 | Novo Nordisk As | Composto, uso do mesmo, composição farmacêutica, e, processo para estimular a liberação do hormÈnio do crescimento pela pituitária de um mamìfero |
US6506782B1 (en) | 1998-02-27 | 2003-01-14 | Athena Neurosciences, Inc. | Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
US6919315B1 (en) | 1998-06-30 | 2005-07-19 | Novo Nordisk A/S | Compounds with growth hormone releasing properties |
US6380184B1 (en) | 1998-10-28 | 2002-04-30 | Bristol-Myers Squibb Co. | Benzoazepines and analogs thereof useful as growth hormone secretagogues |
WO2000025768A1 (en) * | 1998-10-29 | 2000-05-11 | Trega Biosciences, Inc. | Oxadiazole, thiadiazole and triazole derivatives and combinatorial libraries thereof |
CA2362290A1 (en) | 1999-02-18 | 2000-08-24 | Kaken Pharmaceutical Co., Ltd. | Novel amide derivatives as growth hormone secretagogues |
US6518292B1 (en) | 1999-03-12 | 2003-02-11 | Bristol-Myers Squibb Co. | Heterocyclic aromatic compounds usefuls as growth hormone secretagogues |
US6525203B1 (en) | 1999-03-12 | 2003-02-25 | Bristol-Myers Squibb Company | Heterocyclic aromatic compounds useful as growth hormone secretagogues |
US6992081B2 (en) | 2000-03-23 | 2006-01-31 | Elan Pharmaceuticals, Inc. | Compounds to treat Alzheimer's disease |
ATE343562T1 (de) | 2000-03-23 | 2006-11-15 | Elan Pharm Inc | Verbindungen und verfahren zur behandlung der alzheimerschen krankheit |
ES2252230T3 (es) | 2000-05-11 | 2006-05-16 | Bristol-Myers Squibb Company | Analogos de tetrahidroisoquinolina utiles como secretores de la hormona del crecimiento. |
ATE446758T1 (de) | 2000-05-31 | 2009-11-15 | Pfizer Prod Inc | Verwendung von wachstumshormonsekretagoga zur förderung der beweglichkeit des verdauungstrakts |
EP1666452A2 (en) | 2000-06-30 | 2006-06-07 | Elan Pharmaceuticals, Inc. | Compounds to treat Alzheimer's disease |
US6846813B2 (en) * | 2000-06-30 | 2005-01-25 | Pharmacia & Upjohn Company | Compounds to treat alzheimer's disease |
CN1217920C (zh) | 2000-06-30 | 2005-09-07 | 艾兰制药公司 | 治疗早老性痴呆的化合物 |
PE20020276A1 (es) | 2000-06-30 | 2002-04-06 | Elan Pharm Inc | COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER |
US20030096864A1 (en) * | 2000-06-30 | 2003-05-22 | Fang Lawrence Y. | Compounds to treat alzheimer's disease |
MXPA04000140A (es) * | 2001-06-27 | 2004-06-03 | Elan Pharm Inc | Derivados de beta-hidroxiamina utiles en el tratamiento de enfermedad de alzheimer. |
US20070213407A1 (en) * | 2001-06-29 | 2007-09-13 | Elan Pharmaceuticals And Pharmacia & Upjohn Company Llc | Compounds to treat Alzheimer's disease |
AU2002357692A1 (en) | 2001-11-09 | 2003-05-26 | Bristol-Myers Squibb Company | Tetrahydroisoquinoline analogs as modulators of chemokine receptor activity |
CA2477604A1 (en) | 2002-03-13 | 2003-09-25 | Signum Biosciences, Inc. | Modulation of protein methylation and phosphoprotein phosphate |
MY139563A (en) | 2002-09-04 | 2009-10-30 | Bristol Myers Squibb Co | Heterocyclic aromatic compounds useful as growth hormone secretagogues |
US7476653B2 (en) | 2003-06-18 | 2009-01-13 | Tranzyme Pharma, Inc. | Macrocyclic modulators of the ghrelin receptor |
WO2005027913A1 (en) * | 2003-09-19 | 2005-03-31 | Pfizer Products Inc. | Pharmaceutical compositions and methods comprising combinations of 2-alkylidene-19-nor-vitamin d derivatives and a growth hormone secretagogue |
AU2012202459B2 (en) * | 2004-03-15 | 2014-06-12 | Janssen Pharmaceutica, N.V. | Novel compounds as opioid receptor modulators |
AU2013205089B2 (en) * | 2004-03-15 | 2013-12-19 | Janssen Pharmaceutica, N.V. | Novel compounds as opioid receptor modulators |
SI1725537T1 (sl) * | 2004-03-15 | 2011-11-30 | Janssen Pharmaceutica Nv | Nove spojine kot modulatorji opioidnih receptorjev |
WO2005112903A2 (en) * | 2004-05-14 | 2005-12-01 | Novo Nordisk A/S | Use of ghrelin antagonists for improving cognition and memory |
AU2005277389A1 (en) | 2004-08-18 | 2006-03-02 | Elixir Pharmaceuticals, Inc. | Growth-hormone secretagogues |
US8221804B2 (en) * | 2005-02-03 | 2012-07-17 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
US7923041B2 (en) | 2005-02-03 | 2011-04-12 | Signum Biosciences, Inc. | Compositions and methods for enhancing cognitive function |
CA2601674A1 (en) * | 2005-03-14 | 2006-09-21 | Janssen Pharmaceutica N.V. | Process for the preparation of opioid modulators |
CU23558A1 (es) | 2006-02-28 | 2010-07-20 | Ct Ingenieria Genetica Biotech | Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento |
EP2118080B1 (en) | 2007-02-09 | 2016-08-31 | Ocera Therapeutics, Inc. | Macrocyclic ghrelin receptor modulators and methods of using the same |
WO2009132051A1 (en) | 2008-04-21 | 2009-10-29 | Signum Biosciences, Inc. | Compounds, compositions and methods for making the same |
WO2013190520A2 (en) | 2012-06-22 | 2013-12-27 | The General Hospital Corporation | Gh-releasing agents in the treatment of vascular stenosis and associated conditions |
US20140315795A1 (en) | 2012-10-26 | 2014-10-23 | Nlife Therapeutics, S.L. | Compositions and Methods for Selective Delivery of Oligonucleotide Molecules to Cell Types |
US9675587B2 (en) | 2013-03-14 | 2017-06-13 | Allergan Holdings Unlimited Company | Opioid receptor modulator dosage formulations |
US9119832B2 (en) | 2014-02-05 | 2015-09-01 | The Regents Of The University Of California | Methods of treating mild brain injury |
WO2015138882A1 (en) | 2014-03-14 | 2015-09-17 | Aerpio Therapeutics, Inc. | Hptp-beta inhibitors |
WO2017075535A1 (en) | 2015-10-28 | 2017-05-04 | Oxeia Biopharmaceuticals, Inc. | Methods of treating neurodegenerative conditions |
WO2018047139A1 (en) * | 2016-09-12 | 2018-03-15 | Aurigene Discovery Technologies Limited | Compounds as modulators of tigit signalling pathway |
CN114901278A (zh) | 2019-10-29 | 2022-08-12 | 视点制药公司 | Tie-2的小分子激活剂 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SK281963B6 (sk) * | 1993-12-23 | 2001-09-11 | Novo Nordisk A/S | Zlúčeniny ovplyvňujúce uvoľňovanie rastového hormónu, farmaceutické prostriedky s ich obsahom a ich použitie |
US5618792A (en) * | 1994-11-21 | 1997-04-08 | Cortech, Inc. | Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase |
ID18218A (id) | 1995-01-27 | 1998-03-19 | Novo Nordisk As | Senyawa dengan sifat-sifat pelepas hormon pertumbuhan |
US5559128A (en) * | 1995-04-18 | 1996-09-24 | Merck & Co., Inc. | 3-substituted piperidines promote release of growth hormone |
ES2323159T3 (es) | 1995-12-22 | 2009-07-07 | Novo Nordisk A/S | Compuestos con propiedades de liberacion de la hormona del crecimiento. |
US5804578A (en) * | 1996-04-03 | 1998-09-08 | Merck & Co., Inc. | Piperidines, pyrrolidines and hexahydro-1H-azepines promote release of growth hormone |
-
1996
- 1996-01-26 ID IDP960190A patent/ID18218A/id unknown
- 1996-01-26 JP JP52255996A patent/JP4073952B2/ja not_active Expired - Fee Related
- 1996-01-26 DE DE69633003T patent/DE69633003T2/de not_active Expired - Fee Related
- 1996-01-26 EP EP96900550A patent/EP0805816B1/en not_active Expired - Lifetime
- 1996-01-26 UA UA97073973A patent/UA55381C2/uk unknown
- 1996-01-26 CZ CZ972381A patent/CZ238197A3/cs unknown
- 1996-01-26 HU HU9702388A patent/HUP9702388A3/hu unknown
- 1996-01-26 AT AT96900550T patent/ATE272069T1/de not_active IP Right Cessation
- 1996-01-26 MX MX9705710A patent/MX9705710A/es active IP Right Grant
- 1996-01-26 AU AU44315/96A patent/AU705744B2/en not_active Ceased
- 1996-01-26 CN CNB961921846A patent/CN1225471C/zh not_active Expired - Fee Related
- 1996-01-26 IL IL11692396A patent/IL116923A/xx not_active IP Right Cessation
- 1996-01-26 AR ARP960101177A patent/AR003108A1/es unknown
- 1996-01-26 PL PL96321590A patent/PL186511B1/pl not_active IP Right Cessation
- 1996-01-26 CA CA002211381A patent/CA2211381C/en not_active Expired - Fee Related
- 1996-01-26 WO PCT/DK1996/000045 patent/WO1996022997A1/en not_active Application Discontinuation
- 1996-01-26 MY MYPI96000291A patent/MY113488A/en unknown
- 1996-02-27 TW TW085102211A patent/TW482767B/zh not_active IP Right Cessation
-
1997
- 1997-07-17 US US08/897,239 patent/US6013658A/en not_active Expired - Fee Related
- 1997-07-25 NO NO973446A patent/NO973446L/no unknown
-
1999
- 1999-11-19 US US09/443,993 patent/US6350767B1/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AR003108A1 (es) | 1998-07-08 |
ATE272069T1 (de) | 2004-08-15 |
AU4431596A (en) | 1996-08-14 |
DE69633003T2 (de) | 2005-08-18 |
CN1176645A (zh) | 1998-03-18 |
ID18218A (id) | 1998-03-19 |
CA2211381C (en) | 2009-05-19 |
IL116923A0 (en) | 1996-05-14 |
JP4073952B2 (ja) | 2008-04-09 |
DE69633003D1 (de) | 2004-09-02 |
MY113488A (en) | 2002-03-30 |
US6013658A (en) | 2000-01-11 |
NO973446L (no) | 1997-09-26 |
AU705744B2 (en) | 1999-06-03 |
UA55381C2 (uk) | 2003-04-15 |
NO973446D0 (no) | 1997-07-25 |
JPH11500107A (ja) | 1999-01-06 |
PL321590A1 (en) | 1997-12-08 |
US6350767B1 (en) | 2002-02-26 |
CZ238197A3 (en) | 1997-12-17 |
TW482767B (en) | 2002-04-11 |
WO1996022997A1 (en) | 1996-08-01 |
IL116923A (en) | 2000-09-28 |
CA2211381A1 (en) | 1996-08-01 |
EP0805816B1 (en) | 2004-07-28 |
CN1225471C (zh) | 2005-11-02 |
EP0805816A1 (en) | 1997-11-12 |
HUP9702388A3 (en) | 1999-01-28 |
PL186511B1 (pl) | 2004-01-30 |
HUP9702388A2 (hu) | 1998-04-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX9705710A (es) | Compuestos con propiedades de liberacion de la hormona del crecimiento. | |
NZ227788A (en) | Peptide having growth hormone regulatory effects, and compositions | |
AU7672487A (en) | Improved estradiol implant composition and method for preparation | |
AU3434697A (en) | Compounds with growth hormone releasing properties | |
IL102848A0 (en) | Polypeptides having growth hormone releasing activity,their use and pharmaceutical compositions containing them | |
UA43348C2 (uk) | Водна фармацевтична композиція, що включає фактор росту нерва (варіанти) та ліофілізований фармацевтичний склад | |
ES2008408A6 (es) | Un procedimiento para la preparacion de pirazolinas utiles como insecticidas. | |
MX9705954A (es) | Formulaciones y metodos para reducir irritacion de la piel. | |
DE69417252D1 (de) | Verbesserte immunogene zusammensetzung gegen mensliches gastrin 17 | |
EG18379A (en) | Novel pharmacological compounds | |
ES2131528T3 (es) | Nuevos polipeptidos y su uso. | |
KR0180256B1 (en) | Bpc peptides, their preparation and use | |
NO991736L (no) | Bioaktive peptider, anvendelse derav samt fremstilling av slike | |
IL126235A (en) | Compounds with growth hormone releasing properties, pharmaceutical compositions comprising them and their use | |
EG19865A (en) | Arylpyrrole compounds process for their preparation and use as insecticide | |
IL93491A0 (en) | Azolylethylcyclopropanes,their preparation and their use as fungicides and growth regulators | |
BG103905A (en) | New bpc peptide salts with organoprotective activity, method for their preparation and application in medicine | |
DE69327693D1 (de) | Interferon-Alpha/Beta bindendes Protein, seine Herstellung und seine enthaltende pharmazeutische Zusammensetzungen | |
DE69431662T2 (de) | Stabilisierte tablettenformulierung | |
AU6722498A (en) | Disubstituted biphenyloxazolines | |
ZA929909B (en) | Agricultural use of certain compounds, compositions and methods for producing said compounds. | |
GB9710636D0 (en) | Novel mixture | |
IT1284128B1 (it) | Impiego della cloramina t in mangimi per bestiame | |
AU2662300A (en) | Cyclic guanidine derivatives and their use as pesticides | |
NZ510253A (en) | Neuroprotection |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
GB | Transfer or rights |