RU2298416C2 - Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора xi - Google Patents

Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора xi Download PDF

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Publication number
RU2298416C2
RU2298416C2 RU2004105031/15A RU2004105031A RU2298416C2 RU 2298416 C2 RU2298416 C2 RU 2298416C2 RU 2004105031/15 A RU2004105031/15 A RU 2004105031/15A RU 2004105031 A RU2004105031 A RU 2004105031A RU 2298416 C2 RU2298416 C2 RU 2298416C2
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RU
Russia
Prior art keywords
factor
factor vii
vii
polypeptide
related polypeptide
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RU2004105031/15A
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English (en)
Russian (ru)
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RU2004105031A (ru
Inventor
Расмус РЕЙКЕР (DK)
Расмус РЕЙКЕР
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Ново Нордиск Хелт Кэр Аг
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Publication of RU2004105031A publication Critical patent/RU2004105031A/ru
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Publication of RU2298416C2 publication Critical patent/RU2298416C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
RU2004105031/15A 2001-07-20 2002-07-19 Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора xi RU2298416C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200101127 2001-07-20
DKPA200101127 2001-07-20

Publications (2)

Publication Number Publication Date
RU2004105031A RU2004105031A (ru) 2005-04-20
RU2298416C2 true RU2298416C2 (ru) 2007-05-10

Family

ID=8160632

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2004105031/15A RU2298416C2 (ru) 2001-07-20 2002-07-19 Фармацевтическая композиция, содержащая полипептиды фактора vii и полипептиды фактора xi

Country Status (16)

Country Link
EP (1) EP1411973A1 (hu)
JP (1) JP2004534855A (hu)
KR (1) KR20040015821A (hu)
CN (1) CN1304050C (hu)
AU (1) AU2002354846B2 (hu)
BR (1) BR0211256A (hu)
CA (1) CA2452677A1 (hu)
CZ (1) CZ200439A3 (hu)
HU (1) HUP0400976A3 (hu)
IL (1) IL159622A0 (hu)
MX (1) MXPA04000415A (hu)
NO (1) NO20040235L (hu)
PL (1) PL369077A1 (hu)
RU (1) RU2298416C2 (hu)
WO (1) WO2003007983A1 (hu)
ZA (1) ZA200400012B (hu)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9433664B2 (en) 2010-10-06 2016-09-06 Medimmune Limited Factor II and fibrinogen for treatment of haemostatic disorders
RU2800719C2 (ru) * 2017-02-10 2023-07-26 Шанхай Бенемае Фармасьютикалз Корпорэйшн Антитела к фактору xi
US11958911B2 (en) 2017-02-10 2024-04-16 Shanghai Benemae Pharmaceutical Anti-coagulation factor XI antibody

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001005353A2 (en) 1999-07-14 2001-01-25 Novo Nordisk A/S USE OF FVIIa OR A TISSUE FACTOR ANTAGONIST FOR REGULATING GENE EXPRESSION AND CELL MIGRATION OR CHEMOTAXIS
ES2381110T3 (es) 2003-09-09 2012-05-23 Novo Nordisk Health Care Ag Polipéptidos de factor VII de coagulación
RU2006115783A (ru) * 2003-11-20 2007-12-27 Ново Нордиск Хелс Кеа Аг (Ch) Терапевтическое применение фактора xi
ES2579753T3 (es) * 2004-02-05 2016-08-16 Novo Nordisk Health Care Ag Uso del Factor VIIA para tratamiento de complicaciones tardías de traumatismo
WO2006128497A1 (en) * 2005-06-01 2006-12-07 Novo Nordisk A/S Pharmaceutical formulation of factor xi
CN102348462B (zh) 2008-12-19 2015-06-17 巴克斯特国际公司 Tfpi抑制剂和使用方法
CN105566490A (zh) 2010-03-19 2016-05-11 巴克斯特国际公司 Tfpi抑制剂及使用方法
AU2013235741C1 (en) 2012-03-21 2017-12-21 Takeda Pharmaceutical Company Limited TFPI inhibitors and methods of use
JP2017512186A (ja) * 2014-01-31 2017-05-18 ダナ−ファーバー キャンサー インスティテュート， インコーポレイテッド ジヒドロプテリジノン誘導体およびその使用
WO2016201370A1 (en) 2015-06-12 2016-12-15 Dana-Farber Cancer Institute, Inc. Combination therapy of transcription inhibitors and kinase inhibitors
AU2016361478B2 (en) 2015-11-25 2020-09-10 Dana-Farber Cancer Institute, Inc. Bivalent bromodomain inhibitors and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59116213A (ja) * 1982-12-24 1984-07-05 Unitika Ltd エアゾ−ル組成物
JPH0780783B2 (ja) * 1985-11-26 1995-08-30 ノボ ノルディスク アクティーゼルスカブ 出血障害の治療のための第▲ＶＩＩ▼ａ因子を含有する治療組成物
US5580560A (en) * 1989-11-13 1996-12-03 Novo Nordisk A/S Modified factor VII/VIIa
FR2676231A1 (fr) * 1991-05-07 1992-11-13 Aetsrn Concentre de facteur xi de la coagulation sanguine a haute activite specifique, approprie a usage therapeutique et son procede de preparation.
PL204888B1 (pl) * 2000-09-13 2010-02-26 Novo Nordisk Healthcare Ag Wariant polipeptydu czynnika VII, konstrukcja kwasu nukleinowego, rekombinowana komórka gospodarza, zwierzę transgeniczne, sposób wytwarzania wariantu polipeptydu czynnika VII, kompozycja farmaceutyczna i zastosowanie wariantu polipeptydu czynnika VII

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
TORBET J.The trombin activation pathway modulates the assembly, structure and lysis of human plasma clots in vitro/. Thromb.Haemost., 1995, May, v.73(5), p.785-792. *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9433664B2 (en) 2010-10-06 2016-09-06 Medimmune Limited Factor II and fibrinogen for treatment of haemostatic disorders
RU2606155C2 (ru) * 2010-10-06 2017-01-10 Медиммьюн Лимитед Фактор ii и фибриноген для лечения гемостатических нарушений
RU2800719C2 (ru) * 2017-02-10 2023-07-26 Шанхай Бенемае Фармасьютикалз Корпорэйшн Антитела к фактору xi
US11958911B2 (en) 2017-02-10 2024-04-16 Shanghai Benemae Pharmaceutical Anti-coagulation factor XI antibody

Also Published As

Publication number Publication date
PL369077A1 (en) 2005-04-18
AU2002354846B2 (en) 2007-08-02
WO2003007983A1 (en) 2003-01-30
JP2004534855A (ja) 2004-11-18
BR0211256A (pt) 2004-07-27
CN1556710A (zh) 2004-12-22
MXPA04000415A (es) 2004-11-22
CZ200439A3 (cs) 2005-03-16
RU2004105031A (ru) 2005-04-20
IL159622A0 (en) 2004-06-01
CA2452677A1 (en) 2003-01-30
NO20040235L (no) 2004-03-17
KR20040015821A (ko) 2004-02-19
HUP0400976A3 (en) 2006-01-30
HUP0400976A2 (hu) 2004-08-30
EP1411973A1 (en) 2004-04-28
ZA200400012B (en) 2004-08-17
CN1304050C (zh) 2007-03-14

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MM4A The patent is invalid due to non-payment of fees

Effective date: 20080720