AU2002354846B2 - Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides - Google Patents

Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides Download PDF

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Publication number
AU2002354846B2
AU2002354846B2 AU2002354846A AU2002354846A AU2002354846B2 AU 2002354846 B2 AU2002354846 B2 AU 2002354846B2 AU 2002354846 A AU2002354846 A AU 2002354846A AU 2002354846 A AU2002354846 A AU 2002354846A AU 2002354846 B2 AU2002354846 B2 AU 2002354846B2
Authority
AU
Australia
Prior art keywords
factor
factor vii
related polypeptide
vii
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2002354846A
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English (en)
Other versions
AU2002354846A1 (en
Inventor
Rasmus Rojkjaer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk Health Care AG
Original Assignee
Novo Nordisk Health Care AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk Health Care AG filed Critical Novo Nordisk Health Care AG
Publication of AU2002354846A1 publication Critical patent/AU2002354846A1/en
Application granted granted Critical
Publication of AU2002354846B2 publication Critical patent/AU2002354846B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AU2002354846A 2001-07-20 2002-07-19 Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides Ceased AU2002354846B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200101127 2001-07-20
DKPA200101127 2001-07-20
PCT/DK2002/000505 WO2003007983A1 (en) 2001-07-20 2002-07-19 Pharmaceutical composition comprising factor vii polypeptides and factor xi polypeptides

Publications (2)

Publication Number Publication Date
AU2002354846A1 AU2002354846A1 (en) 2003-05-22
AU2002354846B2 true AU2002354846B2 (en) 2007-08-02

Family

ID=8160632

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002354846A Ceased AU2002354846B2 (en) 2001-07-20 2002-07-19 Pharmaceutical composition comprising factor VII polypeptides and factor XI polypeptides

Country Status (16)

Country Link
EP (1) EP1411973A1 (hu)
JP (1) JP2004534855A (hu)
KR (1) KR20040015821A (hu)
CN (1) CN1304050C (hu)
AU (1) AU2002354846B2 (hu)
BR (1) BR0211256A (hu)
CA (1) CA2452677A1 (hu)
CZ (1) CZ200439A3 (hu)
HU (1) HUP0400976A3 (hu)
IL (1) IL159622A0 (hu)
MX (1) MXPA04000415A (hu)
NO (1) NO20040235L (hu)
PL (1) PL369077A1 (hu)
RU (1) RU2298416C2 (hu)
WO (1) WO2003007983A1 (hu)
ZA (1) ZA200400012B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0302052A3 (en) 1999-07-14 2005-12-28 Novo Nordisk Healthcare Ag Use of fviia or a tissue factor antagonist for regulating gene expression and cell migration or chemotaxis
CN101870729A (zh) 2003-09-09 2010-10-27 诺和诺德医疗保健公司 凝固因子ⅶ多肽
TW200529870A (en) * 2003-11-20 2005-09-16 Novo Nordisk Healthcare Ag Therapeutic use of factor XI
JP2007520530A (ja) * 2004-02-05 2007-07-26 ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト 外傷の遅発型合併症の治療のための、ＶＩＩａ因子又はＶＩＩａ因子等価物の使用
WO2006128497A1 (en) * 2005-06-01 2006-12-07 Novo Nordisk A/S Pharmaceutical formulation of factor xi
DK2379096T3 (da) 2008-12-19 2019-11-25 Baxalta GmbH TFPI-inhibitorer og fremgangsmåder til anvendelse
US8450275B2 (en) 2010-03-19 2013-05-28 Baxter International Inc. TFPI inhibitors and methods of use
WO2012045569A1 (en) 2010-10-06 2012-04-12 Medimmune Limited Factor ii and fibrinogen for treatment of haemostatic disorders
HUE046572T2 (hu) 2012-03-21 2020-03-30 Baxalta GmbH TFPI inhibitorok és alkalmazási eljárások
CN105939607A (zh) * 2014-01-31 2016-09-14 达纳-法伯癌症研究所股份有限公司 二氢蝶啶酮衍生物及其用途
EP3307728A4 (en) 2015-06-12 2019-07-17 Dana Farber Cancer Institute, Inc. ASSOCIATION THERAPY USING TRANSCRIPTION INHIBITORS AND KINASE INHIBITORS
EP3380100A4 (en) 2015-11-25 2019-10-02 Dana-Farber Cancer Institute, Inc. BIVALENT BROMODOMAIN INHIBITORS AND USES THEREOF
US11958911B2 (en) 2017-02-10 2024-04-16 Shanghai Benemae Pharmaceutical Anti-coagulation factor XI antibody

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0225160A2 (en) * 1985-11-26 1987-06-10 Novo Nordisk A/S Compositions and methods for the treatment of bleeding disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59116213A (ja) * 1982-12-24 1984-07-05 Unitika Ltd エアゾ−ル組成物
US5580560A (en) * 1989-11-13 1996-12-03 Novo Nordisk A/S Modified factor VII/VIIa
FR2676231A1 (fr) * 1991-05-07 1992-11-13 Aetsrn Concentre de facteur xi de la coagulation sanguine a haute activite specifique, approprie a usage therapeutique et son procede de preparation.
AU2001287550B2 (en) * 2000-09-13 2007-03-22 Novo Nordisk Health Care Ag Human coagulation factor VII variants

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0225160A2 (en) * 1985-11-26 1987-06-10 Novo Nordisk A/S Compositions and methods for the treatment of bleeding disorders

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Bajaj et al (1983) Biochemistry, vol 22, pp 4047-4053 *
Zur et al (1980) J of Biol Chem, vol 255(12), pp 5703-5707 *

Also Published As

Publication number Publication date
CN1304050C (zh) 2007-03-14
JP2004534855A (ja) 2004-11-18
RU2298416C2 (ru) 2007-05-10
MXPA04000415A (es) 2004-11-22
RU2004105031A (ru) 2005-04-20
KR20040015821A (ko) 2004-02-19
CZ200439A3 (cs) 2005-03-16
CA2452677A1 (en) 2003-01-30
CN1556710A (zh) 2004-12-22
PL369077A1 (en) 2005-04-18
EP1411973A1 (en) 2004-04-28
NO20040235L (no) 2004-03-17
BR0211256A (pt) 2004-07-27
ZA200400012B (en) 2004-08-17
HUP0400976A3 (en) 2006-01-30
WO2003007983A1 (en) 2003-01-30
IL159622A0 (en) 2004-06-01
HUP0400976A2 (hu) 2004-08-30

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired