RU2190594C2 - Органические нитраты и фармацевтическая композиция, обладающая ингибирующей агрегацию тромбоцитов активностью, на их основе - Google Patents

Органические нитраты и фармацевтическая композиция, обладающая ингибирующей агрегацию тромбоцитов активностью, на их основе Download PDF

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RU2190594C2
RU2190594C2 RU99112517/04A RU99112517A RU2190594C2 RU 2190594 C2 RU2190594 C2 RU 2190594C2 RU 99112517/04 A RU99112517/04 A RU 99112517/04A RU 99112517 A RU99112517 A RU 99112517A RU 2190594 C2 RU2190594 C2 RU 2190594C2
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iia
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carbon atoms
groups
activity
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RU99112517/04A
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Russian (ru)
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RU99112517A (ru
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Солдато Пьеро Дель
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Никокс С.А.
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/101,2,5-Thiadiazoles; Hydrogenated 1,2,5-thiadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C203/00Esters of nitric or nitrous acid
    • C07C203/02Esters of nitric acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
RU99112517/04A 1996-11-14 1997-11-12 Органические нитраты и фармацевтическая композиция, обладающая ингибирующей агрегацию тромбоцитов активностью, на их основе RU2190594C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT96MI002368A IT1295694B1 (it) 1996-11-14 1996-11-14 Nitrossi derivati per la preparazione di medicamenti ad attivita antitrombinica
ITMI96A002368 1996-11-14

Publications (2)

Publication Number Publication Date
RU99112517A RU99112517A (ru) 2001-04-10
RU2190594C2 true RU2190594C2 (ru) 2002-10-10

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU99112517/04A RU2190594C2 (ru) 1996-11-14 1997-11-12 Органические нитраты и фармацевтическая композиция, обладающая ингибирующей агрегацию тромбоцитов активностью, на их основе

Country Status (18)

Country Link
US (1) US6242432B1 (https=)
EP (1) EP0941218B1 (https=)
JP (1) JP4264137B2 (https=)
KR (1) KR100504122B1 (https=)
CN (1) CN1094931C (https=)
AT (1) ATE226199T1 (https=)
AU (1) AU729423B2 (https=)
BR (1) BR9712959B1 (https=)
CA (1) CA2272063C (https=)
DE (1) DE69716461T2 (https=)
DK (1) DK0941218T3 (https=)
ES (1) ES2186013T3 (https=)
HU (1) HUP0000667A3 (https=)
IL (1) IL129768A (https=)
IT (1) IT1295694B1 (https=)
PT (1) PT941218E (https=)
RU (1) RU2190594C2 (https=)
WO (1) WO1998021193A1 (https=)

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* Cited by examiner, † Cited by third party
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RU2322972C1 (ru) * 2006-09-12 2008-04-27 Илья Николаевич Медведев Способ профилактики тромбозов у больных артериальной гипертонией с метаболическим синдромом

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US7235237B2 (en) 1999-10-29 2007-06-26 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
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Cited By (1)

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Publication number Priority date Publication date Assignee Title
RU2322972C1 (ru) * 2006-09-12 2008-04-27 Илья Николаевич Медведев Способ профилактики тромбозов у больных артериальной гипертонией с метаболическим синдромом

Also Published As

Publication number Publication date
WO1998021193A1 (en) 1998-05-22
CN1242768A (zh) 2000-01-26
HUP0000667A3 (en) 2000-08-28
BR9712959A (pt) 2000-02-01
IL129768A0 (en) 2000-02-29
KR100504122B1 (ko) 2005-07-27
DK0941218T3 (da) 2003-02-17
ES2186013T3 (es) 2003-05-01
ITMI962368A0 (it) 1996-11-14
CA2272063C (en) 2008-05-27
DE69716461T2 (de) 2003-06-26
ITMI962368A1 (it) 1998-05-14
AU5551998A (en) 1998-06-03
IT1295694B1 (it) 1999-05-27
PT941218E (pt) 2003-03-31
JP2001507676A (ja) 2001-06-12
IL129768A (en) 2004-02-19
HUP0000667A2 (en) 2000-07-28
CN1094931C (zh) 2002-11-27
BR9712959B1 (pt) 2010-06-01
CA2272063A1 (en) 1998-05-22
EP0941218A1 (en) 1999-09-15
KR20000053251A (ko) 2000-08-25
JP4264137B2 (ja) 2009-05-13
AU729423B2 (en) 2001-02-01
DE69716461D1 (de) 2002-11-21
US6242432B1 (en) 2001-06-05
ATE226199T1 (de) 2002-11-15
EP0941218B1 (en) 2002-10-16

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Effective date: 20111113