RU2134104C1 - Пероральная композиция для лечения воспалительных заболеваний кишечного тракта - Google Patents

Пероральная композиция для лечения воспалительных заболеваний кишечного тракта Download PDF

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Publication number
RU2134104C1
RU2134104C1 SU5052239A SU5052239A RU2134104C1 RU 2134104 C1 RU2134104 C1 RU 2134104C1 SU 5052239 A SU5052239 A SU 5052239A SU 5052239 A SU5052239 A SU 5052239A RU 2134104 C1 RU2134104 C1 RU 2134104C1
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RU
Russia
Prior art keywords
budesonide
isomer
dosage form
water
form according
Prior art date
Application number
SU5052239A
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English (en)
Russian (ru)
Inventor
Ульмиюс Ян
Original Assignee
Актиеболагет Драко
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20377544&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RU2134104(C1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Актиеболагет Драко filed Critical Актиеболагет Драко
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Publication of RU2134104C1 publication Critical patent/RU2134104C1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
SU5052239A 1989-11-22 1990-11-15 Пероральная композиция для лечения воспалительных заболеваний кишечного тракта RU2134104C1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE8903914A SE8903914D0 (sv) 1989-11-22 1989-11-22 Oral composition for the treatment of inflammatory bowel diseases
SE8903914-3 1989-11-22
PCT/SE1990/000738 WO1991007172A1 (en) 1989-11-22 1990-11-15 Oral composition for the treatment of inflammatory bowel diseases

Publications (1)

Publication Number Publication Date
RU2134104C1 true RU2134104C1 (ru) 1999-08-10

Family

ID=20377544

Family Applications (1)

Application Number Title Priority Date Filing Date
SU5052239A RU2134104C1 (ru) 1989-11-22 1990-11-15 Пероральная композиция для лечения воспалительных заболеваний кишечного тракта

Country Status (36)

Country Link
US (1) US6423340B1 (enExample)
EP (1) EP0502092B1 (enExample)
JP (1) JP3145111B2 (enExample)
KR (1) KR0179042B1 (enExample)
AT (1) ATE125445T1 (enExample)
AU (1) AU643021B2 (enExample)
CA (1) CA2071518C (enExample)
DE (1) DE69021214T2 (enExample)
DK (1) DK0502092T3 (enExample)
EG (1) EG19642A (enExample)
ES (1) ES2074698T3 (enExample)
FI (2) FI104949B (enExample)
GR (1) GR3017691T3 (enExample)
HK (1) HK51897A (enExample)
HR (1) HRP920632B1 (enExample)
HU (2) HU216836B (enExample)
IE (1) IE74854B1 (enExample)
IL (1) IL96415A (enExample)
IS (1) IS1858B (enExample)
LT (1) LT3696B (enExample)
LV (1) LV10183B (enExample)
MY (1) MY104535A (enExample)
NO (1) NO304010B1 (enExample)
NZ (1) NZ235807A (enExample)
PL (1) PL166506B1 (enExample)
PT (1) PT95946A (enExample)
RU (1) RU2134104C1 (enExample)
SA (1) SA90110123B1 (enExample)
SE (1) SE8903914D0 (enExample)
SG (1) SG54210A1 (enExample)
SI (1) SI9012150A (enExample)
TW (1) TW250435B (enExample)
UA (1) UA37196C2 (enExample)
WO (1) WO1991007172A1 (enExample)
YU (1) YU48583B (enExample)
ZA (1) ZA908777B (enExample)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD480Z5 (ro) * 2011-07-07 2012-09-30 Эльвира АНДОН Metodă de tratament al colitei ulceroase nespecifice acute
RU2750937C2 (ru) * 2016-02-09 2021-07-06 Альбирео Аб Пероральный состав холестирамина и его применение
RU2750944C2 (ru) * 2016-02-09 2021-07-06 Альбирео Аб Пероральный состав холестирамина и его применение

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5316772A (en) * 1990-12-19 1994-05-31 Solvay & Cie, S.A. (Societe Anonyme) Bilayered oral pharmaceutical composition with pH dependent release
CZ171095A3 (en) * 1993-01-08 1996-01-17 Astra Ab Novel steroidal derivatives specific for colon or ilium
US5914132A (en) * 1993-02-26 1999-06-22 The Procter & Gamble Company Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
DE4332394A1 (de) * 1993-09-23 1995-03-30 Falk Pharma Gmbh Budesonid-Pellets mit kontrolliertem Freigabeprofil und Verfahren zu ihrer Herstellung
US5686106A (en) * 1995-05-17 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form for colonic delivery
WO1998022095A1 (en) * 1996-11-15 1998-05-28 The Procter & Gamble Company Pharmaceutical dosage form for colonic delivery
SE9604751D0 (sv) 1996-12-20 1996-12-20 Astra Ab New therapy
DE19732903A1 (de) 1997-07-30 1999-02-04 Falk Pharma Gmbh Pellet-Formulierung zur Behandlung des Intestinaltraktes
US6239120B1 (en) 1998-03-17 2001-05-29 Pharmalink Ab Method and means for treating glomerulonephritis
GB9824604D0 (en) 1998-11-11 1999-01-06 Hewlett Healthcare Limited Treatment of allergic conditions
SE9902673D0 (sv) * 1999-07-12 1999-07-12 Astra Ab New composition
AU2002254205B2 (en) * 2001-03-15 2007-05-10 Enteron Pharmaceuticals, Inc. Method of treating inflammatory disorders of the gastrointestinal tract using topical active corticosteroids
DE10250543A1 (de) * 2002-10-29 2004-05-19 Röhm GmbH & Co. KG Mehrschichtige Arzneiform
ES2312844T3 (es) 2002-12-12 2009-03-01 Nycomed Gmbh Medicamento de combinacion de r, r-formoterol y ciclesonida.
WO2004087109A1 (ja) * 2003-03-27 2004-10-14 Hisamitsu Pharmaceutical Co., Inc. 大腸送達性経口医薬製剤、大腸癌治療用経口医薬製剤および大腸炎治療用経口医薬製剤
DE602004028497D1 (de) * 2003-09-15 2010-09-16 Nycomed Gmbh Verwendung von ciclesonid zur behandlung von entzündlichen darmerkrankungen
WO2005025578A1 (en) 2003-09-16 2005-03-24 Altana Pharma Ag Use of ciclesonide for the treatment of respiratory diseases
US8461187B2 (en) 2004-06-16 2013-06-11 Takeda Pharmaceuticals U.S.A., Inc. Multiple PPI dosage form
WO2007056539A2 (en) * 2005-11-08 2007-05-18 Medarex, Inc. Prophylaxis and treatment of enterocolitis associated with anti-ctla-4 antibody therapy
WO2008117814A1 (ja) * 2007-03-26 2008-10-02 Teikoku Seiyaku Co., Ltd. 大腸送達用経口製剤
RU2010119041A (ru) * 2007-10-12 2011-11-20 Такеда Фармасьютикалз Норт Америка, Инк. (Us) Способы лечения нарушений желудочно-кишечного тракта, независимого от потребления пищи
GB0808537D0 (en) * 2008-05-12 2008-06-18 Archimedes Dev Ltd Compositions
CA2739465C (en) * 2008-10-03 2017-01-31 Dr. Falk Pharma Gmbh Compositions and methods for the treatment of bowel diseases with granulated mesalamine
US8945616B2 (en) * 2009-02-17 2015-02-03 Mylan Pharmaceuticals Inc. Controlled release budesonide minitablets
US8945615B2 (en) 2009-02-17 2015-02-03 Mylan Pharmaceuticals Inc. Controlled release budesonide minitablets
MX2013009033A (es) * 2011-02-04 2013-09-06 Optimer Pharmaceuticals Inc Tratamiento de infecciones bacterianas.
SI2659881T1 (en) 2012-04-30 2018-03-30 Tillotts Pharma Ag Formulation of the delayed release medicinal product
EA032504B1 (ru) 2013-10-29 2019-06-28 Тиллоттс Фарма АГ Лекарственный препарат с отсроченным высвобождением и его применение для доставки лекарственного средства
JP2018530535A (ja) * 2015-09-11 2018-10-18 サン・ファーマシューティカル・インダストリーズ・リミテッド ブデゾニドの経口医薬剤形
CN105663091A (zh) * 2016-01-28 2016-06-15 上海信谊百路达药业有限公司 一种布地奈德肠溶缓释胶囊及其制备方法
EP3613414A1 (de) 2018-08-24 2020-02-26 Dr. Falk Pharma Gmbh Pellets mit mehrschichtiger struktur zur verzögerten freisetzung des wirkstoffs im distalen kolon
US11896719B2 (en) 2022-01-24 2024-02-13 Calliditas Therapeutics Ab Pharmaceutical compositions

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983000435A1 (en) * 1981-07-31 1983-02-17 Rhodes, John Orally administrable pharmaceutical compositions
EP0278174A2 (en) * 1986-12-24 1988-08-17 Glaxo Group Limited Use of fluticasone propionate in the preparation of a pharmaceutical composition for the treatment of bowel diseases

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3996356A (en) 1969-07-02 1976-12-07 Hoffmann-La Roche Inc. Composition containing 5-sulfanilamido-3,4-dimethylisoxazole and a trimethoxybenzyl pyrimidine
SE378109B (enExample) 1972-05-19 1975-08-18 Bofors Ab
SE7813246L (sv) 1978-12-22 1980-06-23 Haessle Ab Fast farmaceutisk beredning innehallande kroppar med flera ytskikt
FR2471186A1 (fr) 1979-12-10 1981-06-19 Roussel Uclaf Nouveaux comprimes a delitescence colique, ainsi que leur procede de preparation
SE8003805L (sv) 1980-05-21 1981-11-22 Haessle Ab En farmaceutisk beredning med forbettrade utlosningsegenskap
SE8008524L (sv) 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
SE8306370D0 (sv) 1983-11-18 1983-11-18 Draco Ab Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions
US4708867A (en) 1983-12-19 1987-11-24 Key Pharmaceuticals, Inc. Minipellets
US4606940A (en) 1984-12-21 1986-08-19 The Ohio State University Research Foundation Small particle formation and encapsulation
DE3536267A1 (de) 1985-10-11 1987-04-16 Bayer Ag Azofarbstoffe sowie fluessigkristallines material enthaltend azofarbstoffe
SE8506015D0 (sv) 1985-12-19 1985-12-19 Draco Ab Novel 16,17-acetalsubstituted pregnane 21-oic acid derivatives
US4966770A (en) 1989-07-26 1990-10-30 Himedics, Inc. Prednisone microencapsulated granules
DE10307386A1 (de) 2003-02-21 2004-09-09 Dieter Wildfang Gmbh Verfahren zum außenseitigen Beschichten eines sanitären Auslaufteiles sowie sanitäres Auslaufteil

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1983000435A1 (en) * 1981-07-31 1983-02-17 Rhodes, John Orally administrable pharmaceutical compositions
EP0278174A2 (en) * 1986-12-24 1988-08-17 Glaxo Group Limited Use of fluticasone propionate in the preparation of a pharmaceutical composition for the treatment of bowel diseases

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MD480Z5 (ro) * 2011-07-07 2012-09-30 Эльвира АНДОН Metodă de tratament al colitei ulceroase nespecifice acute
RU2750937C2 (ru) * 2016-02-09 2021-07-06 Альбирео Аб Пероральный состав холестирамина и его применение
RU2750944C2 (ru) * 2016-02-09 2021-07-06 Альбирео Аб Пероральный состав холестирамина и его применение

Also Published As

Publication number Publication date
HU9201700D0 (en) 1992-08-28
AU643021B2 (en) 1993-11-04
NO922004D0 (no) 1992-05-21
IL96415A (en) 1995-11-27
KR0179042B1 (ko) 1999-03-20
IS3644A7 (is) 1991-05-23
TW250435B (enExample) 1995-07-01
ATE125445T1 (de) 1995-08-15
IE904170A1 (en) 1991-05-22
HUT60630A (en) 1992-10-28
KR920703025A (ko) 1992-12-17
FI19991893A7 (fi) 1999-09-06
FI922325L (fi) 1992-05-21
IS1858B (is) 2003-03-27
SA90110123B1 (ar) 1999-06-06
PL166506B1 (pl) 1995-05-31
FI922325A0 (fi) 1992-05-21
PT95946A (pt) 1991-09-13
EP0502092A1 (en) 1992-09-09
AU7786491A (en) 1991-06-13
PL287844A1 (en) 1991-12-02
FI19991893L (fi) 1999-09-06
JP3145111B2 (ja) 2001-03-12
GR3017691T3 (en) 1996-01-31
EP0502092B1 (en) 1995-07-26
DE69021214T2 (de) 1996-01-04
NO922004L (no) 1992-05-21
NZ235807A (en) 1993-02-25
YU48583B (sh) 1998-12-23
HK51897A (en) 1997-05-02
JPH05501705A (ja) 1993-04-02
DE69021214D1 (de) 1995-08-31
US6423340B1 (en) 2002-07-23
LV10183B (en) 1995-08-20
ZA908777B (en) 1991-07-31
ES2074698T3 (es) 1995-09-16
UA37196C2 (uk) 2001-05-15
DK0502092T3 (da) 1995-12-27
HU216836B (hu) 1999-09-28
SE8903914D0 (sv) 1989-11-22
SG54210A1 (en) 1998-11-16
MY104535A (en) 1994-04-30
HRP920632A2 (en) 1995-04-30
LTIP1751A (en) 1995-07-25
IL96415A0 (en) 1991-08-16
CA2071518C (en) 2002-11-12
IE74854B1 (en) 1997-08-13
YU215090A (sr) 1996-01-09
CA2071518A1 (en) 1991-05-23
HRP920632B1 (en) 1999-10-31
FI104949B (fi) 2000-05-15
LV10183A (lv) 1994-10-20
NO304010B1 (no) 1998-10-12
EG19642A (en) 1995-08-30
WO1991007172A1 (en) 1991-05-30
LT3696B (en) 1996-02-26
SI9012150A (sl) 1998-08-31

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