RU2095408C1 - Способ обработки материала из дрожжевых клеток - Google Patents
Способ обработки материала из дрожжевых клеток Download PDFInfo
- Publication number
- RU2095408C1 RU2095408C1 RU9193005155A RU93005155A RU2095408C1 RU 2095408 C1 RU2095408 C1 RU 2095408C1 RU 9193005155 A RU9193005155 A RU 9193005155A RU 93005155 A RU93005155 A RU 93005155A RU 2095408 C1 RU2095408 C1 RU 2095408C1
- Authority
- RU
- Russia
- Prior art keywords
- yeast
- food
- bleached
- cells
- product
- Prior art date
Links
- 210000005253 yeast cell Anatomy 0.000 title claims abstract description 32
- 238000000034 method Methods 0.000 title claims abstract description 24
- 239000000463 material Substances 0.000 title claims description 38
- 240000004808 Saccharomyces cerevisiae Species 0.000 claims abstract description 42
- 239000002699 waste material Substances 0.000 claims abstract description 28
- 235000013305 food Nutrition 0.000 claims abstract description 21
- 239000000126 substance Substances 0.000 claims abstract description 20
- 210000004027 cell Anatomy 0.000 claims abstract description 19
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims abstract description 10
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims abstract description 10
- 159000000011 group IA salts Chemical class 0.000 claims abstract description 8
- 210000002421 cell wall Anatomy 0.000 claims description 12
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 claims description 10
- 239000007844 bleaching agent Substances 0.000 claims description 9
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims description 8
- 238000004061 bleaching Methods 0.000 claims description 8
- 238000005119 centrifugation Methods 0.000 claims description 8
- 238000000605 extraction Methods 0.000 claims description 8
- 239000000787 lecithin Substances 0.000 claims description 8
- 235000010445 lecithin Nutrition 0.000 claims description 8
- 229940067606 lecithin Drugs 0.000 claims description 8
- 238000000926 separation method Methods 0.000 claims description 8
- 235000017557 sodium bicarbonate Nutrition 0.000 claims description 5
- 229910000030 sodium bicarbonate Inorganic materials 0.000 claims description 5
- 239000002253 acid Substances 0.000 claims description 4
- 239000006071 cream Substances 0.000 claims description 4
- 235000007983 food acid Nutrition 0.000 claims description 4
- 239000002265 redox agent Substances 0.000 claims description 4
- 208000035404 Autolysis Diseases 0.000 claims description 3
- 206010057248 Cell death Diseases 0.000 claims description 3
- 230000028043 self proteolysis Effects 0.000 claims description 3
- 239000003153 chemical reaction reagent Substances 0.000 claims description 2
- 239000002198 insoluble material Substances 0.000 claims 1
- 238000010297 mechanical methods and process Methods 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 abstract description 8
- 230000000694 effects Effects 0.000 abstract description 4
- 230000001413 cellular effect Effects 0.000 abstract description 2
- 239000010903 husk Substances 0.000 abstract 1
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 38
- 239000000203 mixture Substances 0.000 description 30
- 239000000047 product Substances 0.000 description 28
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 16
- 229920002498 Beta-glucan Polymers 0.000 description 15
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 14
- 210000000170 cell membrane Anatomy 0.000 description 14
- 239000012528 membrane Substances 0.000 description 14
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 description 13
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 13
- 239000002245 particle Substances 0.000 description 8
- 102000004190 Enzymes Human genes 0.000 description 7
- 108090000790 Enzymes Proteins 0.000 description 7
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 6
- 239000012138 yeast extract Substances 0.000 description 6
- 229920001503 Glucan Polymers 0.000 description 5
- 229940041514 candida albicans extract Drugs 0.000 description 5
- 238000001000 micrograph Methods 0.000 description 5
- 239000007900 aqueous suspension Substances 0.000 description 4
- 230000009089 cytolysis Effects 0.000 description 4
- 239000012467 final product Substances 0.000 description 4
- 238000005187 foaming Methods 0.000 description 4
- WQYVRQLZKVEZGA-UHFFFAOYSA-N hypochlorite Chemical compound Cl[O-] WQYVRQLZKVEZGA-UHFFFAOYSA-N 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 230000000699 topical effect Effects 0.000 description 4
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
- 239000002518 antifoaming agent Substances 0.000 description 3
- 235000010323 ascorbic acid Nutrition 0.000 description 3
- 229960005070 ascorbic acid Drugs 0.000 description 3
- 239000011668 ascorbic acid Substances 0.000 description 3
- 239000002585 base Substances 0.000 description 3
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 3
- 239000000920 calcium hydroxide Substances 0.000 description 3
- 229910001861 calcium hydroxide Inorganic materials 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 230000001804 emulsifying effect Effects 0.000 description 3
- 238000004108 freeze drying Methods 0.000 description 3
- 239000003921 oil Substances 0.000 description 3
- 235000019198 oils Nutrition 0.000 description 3
- 230000000144 pharmacologic effect Effects 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 239000007787 solid Substances 0.000 description 3
- 238000001694 spray drying Methods 0.000 description 3
- WHBHBVVOGNECLV-OBQKJFGGSA-N 11-deoxycortisol Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 WHBHBVVOGNECLV-OBQKJFGGSA-N 0.000 description 2
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 description 2
- CFKMVGJGLGKFKI-UHFFFAOYSA-N 4-chloro-m-cresol Chemical compound CC1=CC(O)=CC=C1Cl CFKMVGJGLGKFKI-UHFFFAOYSA-N 0.000 description 2
- 101710130006 Beta-glucanase Proteins 0.000 description 2
- 206010013911 Dysgeusia Diseases 0.000 description 2
- 102000002322 Egg Proteins Human genes 0.000 description 2
- 108010000912 Egg Proteins Proteins 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 229910019142 PO4 Inorganic materials 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 2
- 239000003513 alkali Substances 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
- 239000003638 chemical reducing agent Substances 0.000 description 2
- 239000007979 citrate buffer Substances 0.000 description 2
- 239000002537 cosmetic Substances 0.000 description 2
- 238000001085 differential centrifugation Methods 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 235000013345 egg yolk Nutrition 0.000 description 2
- 210000002969 egg yolk Anatomy 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000007062 hydrolysis Effects 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000005517 mercerization Methods 0.000 description 2
- 238000002156 mixing Methods 0.000 description 2
- 239000007800 oxidant agent Substances 0.000 description 2
- 239000000575 pesticide Substances 0.000 description 2
- 229960005323 phenoxyethanol Drugs 0.000 description 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
- 239000008363 phosphate buffer Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- CDBYLPFSWZWCQE-UHFFFAOYSA-L sodium carbonate Substances [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 239000002562 thickening agent Substances 0.000 description 2
- 239000000052 vinegar Substances 0.000 description 2
- 235000021419 vinegar Nutrition 0.000 description 2
- 230000002087 whitening effect Effects 0.000 description 2
- CHHHXKFHOYLYRE-UHFFFAOYSA-M 2,4-Hexadienoic acid, potassium salt (1:1), (2E,4E)- Chemical compound [K+].CC=CC=CC([O-])=O CHHHXKFHOYLYRE-UHFFFAOYSA-M 0.000 description 1
- 235000019489 Almond oil Nutrition 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 description 1
- 244000056139 Brassica cretica Species 0.000 description 1
- 235000003351 Brassica cretica Nutrition 0.000 description 1
- 235000003343 Brassica rupestris Nutrition 0.000 description 1
- FIPWRIJSWJWJAI-UHFFFAOYSA-N Butyl carbitol 6-propylpiperonyl ether Chemical compound C1=C(CCC)C(COCCOCCOCCCC)=CC2=C1OCO2 FIPWRIJSWJWJAI-UHFFFAOYSA-N 0.000 description 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 description 1
- 229920000881 Modified starch Polymers 0.000 description 1
- 239000004368 Modified starch Substances 0.000 description 1
- 210000004460 N cell Anatomy 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- VQXSOUPNOZTNAI-UHFFFAOYSA-N Pyrethrin I Natural products CC(=CC1CC1C(=O)OC2CC(=O)C(=C2C)CC=C/C=C)C VQXSOUPNOZTNAI-UHFFFAOYSA-N 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 description 1
- 239000011282 acid tar Substances 0.000 description 1
- 239000012670 alkaline solution Substances 0.000 description 1
- 239000008168 almond oil Substances 0.000 description 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000003254 anti-foaming effect Effects 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- QKSKPIVNLNLAAV-UHFFFAOYSA-N bis(2-chloroethyl) sulfide Chemical compound ClCCSCCCl QKSKPIVNLNLAAV-UHFFFAOYSA-N 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical compound OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 description 1
- 239000004327 boric acid Substances 0.000 description 1
- 229910000020 calcium bicarbonate Inorganic materials 0.000 description 1
- 239000004359 castor oil Substances 0.000 description 1
- 235000019438 castor oil Nutrition 0.000 description 1
- 210000005056 cell body Anatomy 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 239000007795 chemical reaction product Substances 0.000 description 1
- 229960002242 chlorocresol Drugs 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- ALEXXDVDDISNDU-JZYPGELDSA-N cortisol 21-acetate Chemical compound C1CC2=CC(=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)C[C@@H]2O ALEXXDVDDISNDU-JZYPGELDSA-N 0.000 description 1
- 239000008278 cosmetic cream Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 235000015872 dietary supplement Nutrition 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 235000013341 fat substitute Nutrition 0.000 description 1
- 239000003778 fat substitute Substances 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000000855 fermentation Methods 0.000 description 1
- 230000004151 fermentation Effects 0.000 description 1
- 235000012041 food component Nutrition 0.000 description 1
- 239000005417 food ingredient Substances 0.000 description 1
- 235000011194 food seasoning agent Nutrition 0.000 description 1
- 235000003132 food thickener Nutrition 0.000 description 1
- 235000013376 functional food Nutrition 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- ZEMPKEQAKRGZGQ-XOQCFJPHSA-N glycerol triricinoleate Natural products CCCCCC[C@@H](O)CC=CCCCCCCCC(=O)OC[C@@H](COC(=O)CCCCCCCC=CC[C@@H](O)CCCCCC)OC(=O)CCCCCCCC=CC[C@H](O)CCCCCC ZEMPKEQAKRGZGQ-XOQCFJPHSA-N 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- -1 hydrochlorite Chemical compound 0.000 description 1
- 229960001067 hydrocortisone acetate Drugs 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000000415 inactivating effect Effects 0.000 description 1
- 238000009776 industrial production Methods 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 239000000171 lavandula angustifolia l. flower oil Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000007791 liquid phase Substances 0.000 description 1
- 235000004213 low-fat Nutrition 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 238000002483 medication Methods 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 235000019426 modified starch Nutrition 0.000 description 1
- 235000010460 mustard Nutrition 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 230000020477 pH reduction Effects 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 229960005235 piperonyl butoxide Drugs 0.000 description 1
- 239000011736 potassium bicarbonate Substances 0.000 description 1
- 235000015497 potassium bicarbonate Nutrition 0.000 description 1
- 229910000028 potassium bicarbonate Inorganic materials 0.000 description 1
- 229940094025 potassium bicarbonate Drugs 0.000 description 1
- TYJJADVDDVDEDZ-UHFFFAOYSA-M potassium hydrogencarbonate Chemical compound [K+].OC([O-])=O TYJJADVDDVDEDZ-UHFFFAOYSA-M 0.000 description 1
- AKEKKCGPLHMFCI-UHFFFAOYSA-L potassium sodium hydrogen carbonate Chemical compound [Na+].[K+].OC([O-])=O.OC([O-])=O AKEKKCGPLHMFCI-UHFFFAOYSA-L 0.000 description 1
- 239000004302 potassium sorbate Substances 0.000 description 1
- 235000010241 potassium sorbate Nutrition 0.000 description 1
- 229940069338 potassium sorbate Drugs 0.000 description 1
- HYJYGLGUBUDSLJ-UHFFFAOYSA-N pyrethrin Natural products CCC(=O)OC1CC(=C)C2CC3OC3(C)C2C2OC(=O)C(=C)C12 HYJYGLGUBUDSLJ-UHFFFAOYSA-N 0.000 description 1
- VJFUPGQZSXIULQ-XIGJTORUSA-N pyrethrin II Chemical compound CC1(C)[C@H](/C=C(\C)C(=O)OC)[C@H]1C(=O)O[C@@H]1C(C)=C(C\C=C/C=C)C(=O)C1 VJFUPGQZSXIULQ-XIGJTORUSA-N 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000010802 sludge Substances 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 229940001593 sodium carbonate Drugs 0.000 description 1
- 235000017550 sodium carbonate Nutrition 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000007790 solid phase Substances 0.000 description 1
- 239000002195 soluble material Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
- 235000019640 taste Nutrition 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/06—Lysis of microorganisms
- C12N1/063—Lysis of microorganisms of yeast
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/20—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
- A23L29/269—Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of microbial origin, e.g. xanthan or dextran
- A23L29/271—Curdlan; beta-1-3 glucan; Polysaccharides produced by agrobacterium or alcaligenes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/14—Yeasts or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
- A23L33/24—Cellulose or derivatives thereof
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Processing Of Solid Wastes (AREA)
- Cosmetics (AREA)
- General Preparation And Processing Of Foods (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Fertilizers (AREA)
- Peptides Or Proteins (AREA)
- Seasonings (AREA)
- Jellies, Jams, And Syrups (AREA)
- Confectionery (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Chemical Treatment Of Metals (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB909022560A GB9022560D0 (en) | 1990-10-17 | 1990-10-17 | Processing of waste |
| GB9022560.8 | 1990-10-17 | ||
| PCT/GB1991/001819 WO1992007064A1 (en) | 1990-10-17 | 1991-10-17 | Processing of yeast refuse and resulting product |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU93005155A RU93005155A (ru) | 1997-10-27 |
| RU2095408C1 true RU2095408C1 (ru) | 1997-11-10 |
Family
ID=10683877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU9193005155A RU2095408C1 (ru) | 1990-10-17 | 1991-10-17 | Способ обработки материала из дрожжевых клеток |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US5968811A (enExample) |
| EP (1) | EP0553176B1 (enExample) |
| JP (1) | JP3347724B2 (enExample) |
| AT (1) | ATE180829T1 (enExample) |
| AU (1) | AU659417B2 (enExample) |
| BG (1) | BG60684B1 (enExample) |
| CA (1) | CA2094277C (enExample) |
| CO (1) | CO4750725A1 (enExample) |
| DE (1) | DE69131296T2 (enExample) |
| DK (1) | DK0553176T3 (enExample) |
| EE (1) | EE03059B1 (enExample) |
| ES (1) | ES2132094T3 (enExample) |
| FI (1) | FI110516B (enExample) |
| GB (1) | GB9022560D0 (enExample) |
| GR (1) | GR3031060T3 (enExample) |
| HU (1) | HU218604B (enExample) |
| ID (2) | ID978B (enExample) |
| IE (1) | IE913567A1 (enExample) |
| IN (2) | IN177624B (enExample) |
| LV (1) | LV10301B (enExample) |
| MX (1) | MX9101622A (enExample) |
| MY (1) | MY131626A (enExample) |
| NO (1) | NO311042B1 (enExample) |
| NZ (2) | NZ240266A (enExample) |
| PH (1) | PH31065A (enExample) |
| PT (1) | PT99255B (enExample) |
| RO (1) | RO113369B1 (enExample) |
| RU (1) | RU2095408C1 (enExample) |
| TW (1) | TW211574B (enExample) |
| WO (1) | WO1992007064A1 (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2177695C2 (ru) * | 1999-02-15 | 2002-01-10 | Санкт-Петербургская Государственная Химико-Фармацевтическая Академия | Пищевая добавка "криласорб" |
| RU2216595C1 (ru) * | 2002-11-18 | 2003-11-20 | Закрытое акционерное общество "Торгово-закупочная фирма ВАИГ" | Способ получения бета-глюканов клеточной стенки дрожжей |
| RU2496326C2 (ru) * | 2011-08-11 | 2013-10-27 | Валентина Еремеевна Куцакова | Способ получения белковой добавки |
| RU2849073C1 (ru) * | 2025-08-05 | 2025-10-22 | Общество с ограниченной ответственностью "Микробные нутриенты иммунокорректоры" | Способ получения биологически активных лизатов дрожжей с комплексным иммуномодулирующим, детоксикационным действием и нутритивной поддержкой |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9208371D0 (en) * | 1992-04-16 | 1992-06-03 | Cpc International Inc | Yeast debris products |
| US5545557A (en) * | 1993-04-15 | 1996-08-13 | Cpc International Inc. | Water insoluble coloring agent |
| IT1312090B1 (it) * | 1999-04-22 | 2002-04-04 | Ecoser S R L | Microrganismi inattivati comprendenti sostanze solubili e/osolubilizzabili ad attivita' farmacologica e/o sostanze nutrizionali |
| AU2001279796A1 (en) | 2000-08-03 | 2002-02-18 | Abac R & D Gmbh | Isolation of glucan particles and uses thereof |
| US6531178B2 (en) * | 2000-12-08 | 2003-03-11 | Quaker Oats/Rhone-Poulenc Partnership | β-glucan process, additive and food product |
| BE1014638A6 (fr) | 2002-02-12 | 2004-02-03 | Univ Liege | Methode de preparation de derives de la paroi cellulaire a partir de biomasse. |
| CN100537741C (zh) * | 2002-08-21 | 2009-09-09 | 麒麟麦酒株式会社 | 脱色酵母细胞壁组分 |
| AU2003257658A1 (en) | 2002-08-21 | 2004-03-11 | Asahi Kasei Chemicals Corporation | Decolorized yeast cell wall fraction |
| DE10309281A1 (de) * | 2003-03-04 | 2004-09-23 | Satia Gmbh | Verfahren zur Herstellung eines beta-1,3-Glukans mit verbesserten Eigenschaften |
| ES2899590T3 (es) | 2004-01-23 | 2022-03-14 | Eden Research Plc | Métodos de eliminación de nematodos que comprenden la aplicación de un componente terpénico |
| JPWO2004075621A1 (ja) * | 2004-03-11 | 2007-08-23 | 株式会社資生堂 | 抗老化剤およびコラーゲン産生促進剤 |
| SI2338332T1 (sl) | 2004-05-20 | 2014-06-30 | Eden Research Plc | Votli delec glukana ali votli delec stene celice, ki enkapsulira komponento terpena |
| US7740861B2 (en) | 2004-06-16 | 2010-06-22 | University Of Massachusetts | Drug delivery product and methods |
| ES2375995T3 (es) | 2004-09-17 | 2012-03-08 | University Of Massachusetts | Composiciones y sus usos para deficiencias de enzima lisosomal. |
| CA2607004C (en) | 2005-05-05 | 2016-01-26 | Sensient Flavors Inc. | Production of beta-glucans and mannans |
| JP4545063B2 (ja) * | 2005-08-05 | 2010-09-15 | キリンホールディングス株式会社 | 皮膚状態改善組成物 |
| JP5489462B2 (ja) * | 2005-10-24 | 2014-05-14 | ユニバーシティ オブ マサチューセッツ | 骨病状の遺伝子治療のための組成物およびそれらの使用法 |
| AP2901A (en) | 2005-11-30 | 2014-05-31 | Eden Research Plc | Compositions and methods comprising terpenes or terpene mixtures selected form thymol, eugenol, geraniol, citral, and L-carvone |
| WO2007063267A1 (en) | 2005-11-30 | 2007-06-07 | Eden Research Plc | Terpene-containing compositions and methods of making and using them |
| CN101528245A (zh) * | 2006-08-24 | 2009-09-09 | 麒麟控股株式会社 | 用于改善皮肤状态的组合物 |
| WO2008032134A1 (es) * | 2006-09-11 | 2008-03-20 | Compana Nacional De Levaduras Levapan S.A. | Proceso para la obtencion de glucan de levadura por autolisis de celulas de levadura saccharomyces cerevisiae de panaderia |
| US8389485B2 (en) | 2007-10-29 | 2013-03-05 | University Of Massachusetts | Encapsulated nanoparticles for nucleic acid delivery |
| US8815818B2 (en) | 2008-07-18 | 2014-08-26 | Rxi Pharmaceuticals Corporation | Phagocytic cell delivery of RNAI |
| US9493774B2 (en) | 2009-01-05 | 2016-11-15 | Rxi Pharmaceuticals Corporation | Inhibition of PCSK9 through RNAi |
| DE102009023549A1 (de) | 2009-05-30 | 2010-12-09 | Nateco2 Gmbh & Co. Kg | Verwendung von Hopfen zur Herstellung eines Teeaufgusses sowie Hopfentee |
| CN103200945B (zh) | 2010-03-24 | 2016-07-06 | 雷克西制药公司 | 眼部症候中的rna干扰 |
| AU2011232365A1 (en) | 2010-03-24 | 2012-10-25 | Rxi Pharmaceuticals Corporation | RNA interference in dermal and fibrotic indications |
| WO2012024229A1 (en) | 2010-08-14 | 2012-02-23 | University Of Massachusetts | Yeast cell wall particle for receptor-targeted nanoparticle delivery |
| TWI652992B (zh) * | 2011-10-31 | 2019-03-11 | 興人生命科學股份有限公司 | 酵母來源之調味料、酵母蛋白質組成物之製造方法、及酵母來源之調味料之製造方法 |
| GB201220940D0 (en) | 2012-11-21 | 2013-01-02 | Eden Research Plc | Method P |
| CA2932753A1 (en) | 2013-12-04 | 2015-06-11 | Rxi Pharmaceuticals Corporation | Methods for treatment of wound healing utilizing chemically modified oligonucleotides |
| WO2015168108A2 (en) | 2014-04-28 | 2015-11-05 | Rxi Pharmaceuticals Corporation | Methods for treating cancer using nucleic targeting mdm2 or mycn |
| JP2017514908A (ja) | 2014-05-01 | 2017-06-08 | アールエックスアイ ファーマシューティカルズ コーポレーション | 核酸分子を利用する目の前部における障害の処置のための方法 |
| EP3188799B1 (en) | 2014-09-05 | 2022-07-06 | Phio Pharmaceuticals Corp. | Methods for treating aging and skin disorders using nucleic acids targeting tyr or mmp1 |
| EP3234141A4 (en) | 2014-12-18 | 2018-06-20 | Alnylam Pharmaceuticals, Inc. | Reversir tm compounds |
| WO2017007825A1 (en) | 2015-07-06 | 2017-01-12 | Rxi Pharmaceuticals Corporation | Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach |
| JP6983752B2 (ja) | 2015-07-06 | 2021-12-17 | フィオ ファーマシューティカルズ コーポレーションPhio Pharmaceuticals Corp. | スーパーオキシドディスムターゼ１（ｓｏｄ１）を標的とする核酸分子 |
| JP2018531037A (ja) | 2015-10-19 | 2018-10-25 | アールエックスアイ ファーマシューティカルズ コーポレーション | 長い非コードｒｎａを標的とする減少したサイズの自己送達型核酸化合物 |
| IT201600069379A1 (it) * | 2016-07-04 | 2018-01-04 | Prosol S P A | Composizione sostanzialmente costituita da pareti cellulari di lievito e procedimento per la sua preparazione |
| EP3612152A4 (en) | 2017-04-19 | 2021-02-17 | Phio Pharmaceuticals Corp. | TOPICAL ADMINISTRATION OF NUCLEIC ACID COMPOUNDS |
| JP6682052B2 (ja) * | 2018-01-19 | 2020-04-15 | 日本製紙株式会社 | 化粧用組成物 |
| GB2579182B (en) | 2018-11-21 | 2021-01-20 | Mat X Limited | Binder materials |
| CA3160657A1 (en) | 2019-11-08 | 2021-05-14 | Phio Pharmaceuticals Corp. | Chemically modified oligonucleotides targeting bromodomain containing protein 4 (brd4) for immunotherapy |
| CO2020004754A1 (es) | 2020-04-17 | 2020-10-20 | Compania Nac De Levaduras Levapan S A | Proceso de obtención de β-glucano a partir de levadura de panadería |
| AR131799A1 (es) | 2023-02-09 | 2025-04-30 | Alnylam Pharmaceuticals Inc | Moléculas de reversir y métodos para su uso |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3975553A (en) * | 1965-03-08 | 1976-08-17 | Henri Griffon | Deproteination of yeast cells |
| GB1144876A (en) * | 1966-03-07 | 1969-03-12 | Henry Griffon | A deproteinated yeast cell composition and products resulting therefrom |
| US4122196A (en) * | 1974-11-18 | 1978-10-24 | Anheuser-Busch, Incorporated | Process for the manufacture of yeast glycan |
| JPS5592672A (en) * | 1979-01-05 | 1980-07-14 | Ajinomoto Co Inc | Preparation of yeast extract |
| US4252836A (en) * | 1979-11-23 | 1981-02-24 | Standard Oil Company (Indiana) | Spreadable food product |
| US4765992A (en) * | 1984-06-01 | 1988-08-23 | Universite De Bordeaux Ii | Stimulation of alcoholic fermentation by adsorption of toxic substances with cell walls |
| US5037972A (en) * | 1984-11-28 | 1991-08-06 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
| US4810646A (en) * | 1984-11-28 | 1989-03-07 | Massachusetts Institute Of Technology | Glucan compositions and process for preparation thereof |
| US4992540A (en) * | 1984-11-28 | 1991-02-12 | Massachusetts Institute Of Technology | Glucan composition and process for preparation thereof |
| US4962094A (en) | 1988-10-28 | 1990-10-09 | Alpha Beta Technology, Inc. | Glucan dietary additives |
| JPH0732870B2 (ja) * | 1990-04-20 | 1995-04-12 | 三菱製紙株式会社 | マイクロカプセルの製造方法 |
| EP0460945B1 (en) * | 1990-06-05 | 1995-10-11 | Mitsubishi Paper Mills, Ltd. | Process for producing microcapsules |
| CA2071633A1 (en) * | 1990-10-11 | 1992-04-12 | Manssur Yalpani | Amides derived from sugar alcohols suitable as sugar substitutes |
-
1990
- 1990-10-17 GB GB909022560A patent/GB9022560D0/en active Pending
-
1991
- 1991-10-16 CO CO92348998A patent/CO4750725A1/es unknown
- 1991-10-16 PH PH43300A patent/PH31065A/en unknown
- 1991-10-16 IE IE356791A patent/IE913567A1/en not_active IP Right Cessation
- 1991-10-17 PT PT99255A patent/PT99255B/pt not_active IP Right Cessation
- 1991-10-17 MY MYPI91001922A patent/MY131626A/en unknown
- 1991-10-17 DK DK91918160T patent/DK0553176T3/da active
- 1991-10-17 NZ NZ240266A patent/NZ240266A/en not_active IP Right Cessation
- 1991-10-17 ID IDP96054491A patent/ID978B/id unknown
- 1991-10-17 HU HU9301120A patent/HU218604B/hu not_active IP Right Cessation
- 1991-10-17 RO RO93-00533A patent/RO113369B1/ro unknown
- 1991-10-17 MX MX9101622A patent/MX9101622A/es not_active IP Right Cessation
- 1991-10-17 DE DE69131296T patent/DE69131296T2/de not_active Expired - Fee Related
- 1991-10-17 AT AT91918160T patent/ATE180829T1/de not_active IP Right Cessation
- 1991-10-17 JP JP51651091A patent/JP3347724B2/ja not_active Expired - Fee Related
- 1991-10-17 WO PCT/GB1991/001819 patent/WO1992007064A1/en not_active Ceased
- 1991-10-17 ES ES91918160T patent/ES2132094T3/es not_active Expired - Lifetime
- 1991-10-17 TW TW080108206A patent/TW211574B/zh active
- 1991-10-17 EP EP91918160A patent/EP0553176B1/en not_active Expired - Lifetime
- 1991-10-17 NZ NZ250731A patent/NZ250731A/en not_active IP Right Cessation
- 1991-10-17 RU RU9193005155A patent/RU2095408C1/ru not_active IP Right Cessation
- 1991-10-17 ID IDP61191A patent/ID973B/id unknown
- 1991-10-17 CA CA002094277A patent/CA2094277C/en not_active Expired - Fee Related
- 1991-10-17 AU AU87248/91A patent/AU659417B2/en not_active Ceased
- 1991-10-21 IN IN794CA1991 patent/IN177624B/en unknown
-
1993
- 1993-04-15 BG BG97637A patent/BG60684B1/bg unknown
- 1993-04-16 NO NO19931422A patent/NO311042B1/no not_active IP Right Cessation
- 1993-04-16 FI FI931737A patent/FI110516B/fi active
- 1993-09-24 LV LVP-93-1093A patent/LV10301B/xx unknown
-
1994
- 1994-11-23 EE EE9400300A patent/EE03059B1/xx not_active IP Right Cessation
-
1995
- 1995-06-07 US US08/484,691 patent/US5968811A/en not_active Expired - Lifetime
-
1996
- 1996-04-12 IN IN676CA1996 patent/IN191901B/en unknown
-
1999
- 1999-08-23 GR GR990402139T patent/GR3031060T3/el unknown
Non-Patent Citations (1)
| Title |
|---|
| GB, патент, 4810648, кл.C 12P 19/04, 1989. * |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2177695C2 (ru) * | 1999-02-15 | 2002-01-10 | Санкт-Петербургская Государственная Химико-Фармацевтическая Академия | Пищевая добавка "криласорб" |
| RU2216595C1 (ru) * | 2002-11-18 | 2003-11-20 | Закрытое акционерное общество "Торгово-закупочная фирма ВАИГ" | Способ получения бета-глюканов клеточной стенки дрожжей |
| RU2496326C2 (ru) * | 2011-08-11 | 2013-10-27 | Валентина Еремеевна Куцакова | Способ получения белковой добавки |
| RU2849073C1 (ru) * | 2025-08-05 | 2025-10-22 | Общество с ограниченной ответственностью "Микробные нутриенты иммунокорректоры" | Способ получения биологически активных лизатов дрожжей с комплексным иммуномодулирующим, детоксикационным действием и нутритивной поддержкой |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU2095408C1 (ru) | Способ обработки материала из дрожжевых клеток | |
| CA1052307A (fr) | Procede d'extraction et de traitement de glycoproteines, de mucopolysaccharides et de substances qui les accompagnent | |
| AU667348B2 (en) | Yeast debris products | |
| FR2518570A1 (fr) | Enzyme destinee a la decomposition d'un hydrate de carbone a poids moleculaire eleve, hydrate de carbone ainsi obtenu, procede de selection d'un micro-organisme produisant ladite enzyme et procede de production d'une telle enzyme | |
| RU2148636C1 (ru) | Способ получения дрожжевого низкомолекулярного экстракта и вещество, получаемое этим способом | |
| US6274370B1 (en) | Yeast debris products | |
| US1922484A (en) | Extracting oil from animal tissue and the lipoid substances by papain digestion | |
| JPH0441997B2 (enExample) | ||
| EP0466922B1 (en) | Production of yeast extract | |
| US4195097A (en) | Method for preparing enzymaytic composition for acceleration of ageing of meat products | |
| SU503532A3 (ru) | Способ получени фермента дл лизиса клеток микроорганизмов | |
| KR100639847B1 (ko) | 온도조절에 의하여 효모를 자가분해 시켜 효모 추출물을생산하는 방법 | |
| JPS61227827A (ja) | 界面活性物質 | |
| RU2542123C1 (ru) | Способ получения белковой добавки для обогащения селеном пищевых продуктов | |
| JPS59501933A (ja) | 清澄化した酪産乳漿ラクト−ス透過物を培地および他の商業的に有用な製品への転換 | |
| KR20040030010A (ko) | 천연 효소 뽕잎 차와 그 제조방법 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20051018 |