RU2020130012A - Способ лечения фиброзного заболевания - Google Patents

Способ лечения фиброзного заболевания Download PDF

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RU2020130012A
RU2020130012A RU2020130012A RU2020130012A RU2020130012A RU 2020130012 A RU2020130012 A RU 2020130012A RU 2020130012 A RU2020130012 A RU 2020130012A RU 2020130012 A RU2020130012 A RU 2020130012A RU 2020130012 A RU2020130012 A RU 2020130012A
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Russia
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optionally substituted
nhc
days
aryl
carbocyclyl
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RU2020130012A
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Russian (ru)
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Брэд Оуэн БАКМЕН
Прабха ИБРАХИМ
П.Т. Рави РАДЖАГОПАЛАН
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Блэйд Терапьютикс, Инк.
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    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
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    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
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    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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    • C07D285/04—Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
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