JP2021519764A5 - - Google Patents

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Publication number
JP2021519764A5
JP2021519764A5 JP2020552324A JP2020552324A JP2021519764A5 JP 2021519764 A5 JP2021519764 A5 JP 2021519764A5 JP 2020552324 A JP2020552324 A JP 2020552324A JP 2020552324 A JP2020552324 A JP 2020552324A JP 2021519764 A5 JP2021519764 A5 JP 2021519764A5
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JP
Japan
Prior art keywords
optionally substituted
substituted
membered
nhc
days
Prior art date
Application number
JP2020552324A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2019190999A5 (https=
JP2021519764A (ja
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Application filed filed Critical
Priority claimed from PCT/US2019/023917 external-priority patent/WO2019190999A1/en
Publication of JP2021519764A publication Critical patent/JP2021519764A/ja
Publication of JP2021519764A5 publication Critical patent/JP2021519764A5/ja
Publication of JPWO2019190999A5 publication Critical patent/JPWO2019190999A5/ja
Pending legal-status Critical Current

Links

JP2020552324A 2018-03-28 2019-03-25 線維性疾患を処置する方法 Pending JP2021519764A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862649428P 2018-03-28 2018-03-28
US62/649,428 2018-03-28
PCT/US2019/023917 WO2019190999A1 (en) 2018-03-28 2019-03-25 Method of treating fibrotic disease

Publications (3)

Publication Number Publication Date
JP2021519764A JP2021519764A (ja) 2021-08-12
JP2021519764A5 true JP2021519764A5 (https=) 2022-03-31
JPWO2019190999A5 JPWO2019190999A5 (https=) 2022-03-31

Family

ID=68060720

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2020552324A Pending JP2021519764A (ja) 2018-03-28 2019-03-25 線維性疾患を処置する方法

Country Status (15)

Country Link
US (1) US20210113560A1 (https=)
EP (1) EP3774785A4 (https=)
JP (1) JP2021519764A (https=)
KR (1) KR20200139721A (https=)
CN (1) CN112166111A (https=)
AU (1) AU2019242595A1 (https=)
BR (1) BR112020019325A2 (https=)
CA (1) CA3093749A1 (https=)
CL (1) CL2020002465A1 (https=)
IL (1) IL277500A (https=)
MX (1) MX2020010034A (https=)
RU (1) RU2020130012A (https=)
SG (1) SG11202008773PA (https=)
TW (1) TW202003503A (https=)
WO (1) WO2019190999A1 (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3481835A4 (en) 2016-07-05 2020-02-26 Blade Therapeutics, Inc. CALPAIN MODULATORS AND THERAPEUTIC USE THEREOF
BR112019006110A2 (pt) 2016-09-28 2019-09-10 Blade Therapeutics Inc moduladores de calpaína e usos terapêuticos dos mesmos
CA3095164A1 (en) * 2018-03-28 2019-10-03 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof
WO2020006294A1 (en) * 2018-06-28 2020-01-02 Blade Therapeutics, Inc. Methods of treating liver fibrosis using calpain inhibitors
PH12022553378A1 (en) 2020-06-10 2024-03-25 Univ Leuven Kath Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections
JP2024525589A (ja) 2021-07-09 2024-07-12 アリゴス セラピューティクス インコーポレイテッド 抗ウイルス化合物
WO2023043816A1 (en) 2021-09-17 2023-03-23 Aligos Therapeutics, Inc. Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09500087A (ja) * 1992-06-24 1997-01-07 コーテックス ファーマシューティカルズ インコーポレイテッド カルパイン活性の増大に関連した健康障害の抑制及び処置におけるカルパイン阻害剤の使用法
DE69431718T2 (de) * 1993-04-30 2003-07-10 Merck & Co., Inc. Thrombin-inhibitoren
AU5526098A (en) * 1996-12-23 1998-07-17 Biochem Pharma Inc. Bicyclic thrombin inhibitors
ID22904A (id) * 1997-05-02 1999-12-16 Akzo Nobel Nv Penghambat serin protease
DE19817459A1 (de) * 1998-04-20 1999-10-21 Basf Ag Neue heterozyklische substituierte Amide, Herstellung und Anwendung
US20100094755A1 (en) * 2008-10-09 2010-04-15 Nelnet Business Solutions, Inc. Providing payment data tokens for online transactions utilizing hosted inline frames
TWI519530B (zh) * 2009-02-20 2016-02-01 艾伯維德國有限及兩合公司 羰醯胺化合物及其作為鈣蛋白酶(calpain)抑制劑之用途
WO2012076639A1 (en) * 2010-12-09 2012-06-14 Abbott Gmbh & Co. Kg Carboxamide compounds and their use as calpain inhibitors v
JP2015512427A (ja) * 2012-04-03 2015-04-27 アッヴィ・ドイチュラント・ゲー・エム・ベー・ハー・ウント・コー・カー・ゲー カルボキサミド化合物およびそれのカルパイン阻害薬vとしての使用
CN104955801B (zh) * 2012-11-30 2017-10-31 诺沃梅迪科斯有限公司 取代的二芳基磺酰胺及其用途
CN105792831A (zh) * 2013-10-08 2016-07-20 普罗麦迪奥股份有限公司 用于治疗纤维化癌症的方法
BR112019006110A2 (pt) * 2016-09-28 2019-09-10 Blade Therapeutics Inc moduladores de calpaína e usos terapêuticos dos mesmos
CA3095164A1 (en) * 2018-03-28 2019-10-03 Blade Therapeutics, Inc. Calpain modulators and therapeutic uses thereof

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