JP2021519312A5 - - Google Patents
Info
- Publication number
- JP2021519312A5 JP2021519312A5 JP2020551973A JP2020551973A JP2021519312A5 JP 2021519312 A5 JP2021519312 A5 JP 2021519312A5 JP 2020551973 A JP2020551973 A JP 2020551973A JP 2020551973 A JP2020551973 A JP 2020551973A JP 2021519312 A5 JP2021519312 A5 JP 2021519312A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- optionally substituted
- nhc
- group
- membered
- Prior art date
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862649451P | 2018-03-28 | 2018-03-28 | |
| US62/649,451 | 2018-03-28 | ||
| PCT/US2019/023457 WO2019190885A1 (en) | 2018-03-28 | 2019-03-21 | Calpain modulators and therapeutic uses thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2021519312A JP2021519312A (ja) | 2021-08-10 |
| JP2021519312A5 true JP2021519312A5 (https=) | 2022-03-03 |
| JPWO2019190885A5 JPWO2019190885A5 (https=) | 2022-03-03 |
Family
ID=68060735
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020551973A Pending JP2021519312A (ja) | 2018-03-28 | 2019-03-21 | カルパインモジュレーター及びその治療的使用 |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20210009564A1 (https=) |
| EP (1) | EP3774737A4 (https=) |
| JP (1) | JP2021519312A (https=) |
| KR (1) | KR20200139702A (https=) |
| CN (1) | CN112204014A (https=) |
| AR (1) | AR115303A1 (https=) |
| AU (1) | AU2019242387A1 (https=) |
| BR (1) | BR112020019560A2 (https=) |
| CA (1) | CA3095164A1 (https=) |
| CL (1) | CL2020002496A1 (https=) |
| CO (1) | CO2020012359A2 (https=) |
| EC (1) | ECSP20068210A (https=) |
| IL (1) | IL277548A (https=) |
| MX (1) | MX2020010033A (https=) |
| PE (1) | PE20212111A1 (https=) |
| PH (1) | PH12020551555A1 (https=) |
| RU (1) | RU2020130022A (https=) |
| SG (1) | SG11202008750XA (https=) |
| TW (1) | TW202003472A (https=) |
| WO (1) | WO2019190885A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3481835A4 (en) | 2016-07-05 | 2020-02-26 | Blade Therapeutics, Inc. | CALPAIN MODULATORS AND THERAPEUTIC USE THEREOF |
| BR112019006110A2 (pt) | 2016-09-28 | 2019-09-10 | Blade Therapeutics Inc | moduladores de calpaína e usos terapêuticos dos mesmos |
| KR20200139721A (ko) * | 2018-03-28 | 2020-12-14 | 블레이드 테라퓨틱스, 인크. | 섬유성 질환을 치료하는 방법 |
| WO2020006294A1 (en) * | 2018-06-28 | 2020-01-02 | Blade Therapeutics, Inc. | Methods of treating liver fibrosis using calpain inhibitors |
| PH12022553378A1 (en) | 2020-06-10 | 2024-03-25 | Univ Leuven Kath | Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections |
| JP2024525589A (ja) | 2021-07-09 | 2024-07-12 | アリゴス セラピューティクス インコーポレイテッド | 抗ウイルス化合物 |
| WO2023043816A1 (en) | 2021-09-17 | 2023-03-23 | Aligos Therapeutics, Inc. | Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9102462D0 (sv) * | 1991-08-28 | 1991-08-28 | Astra Ab | New isosteric peptides |
| JPH09500087A (ja) * | 1992-06-24 | 1997-01-07 | コーテックス ファーマシューティカルズ インコーポレイテッド | カルパイン活性の増大に関連した健康障害の抑制及び処置におけるカルパイン阻害剤の使用法 |
| DE19642591A1 (de) * | 1996-10-15 | 1998-04-16 | Basf Ag | Neue Piperidin-Ketocarbonsäure-Derivate, deren Herstellung und Anwendung |
| US6083944A (en) * | 1997-10-07 | 2000-07-04 | Cephalon, Inc. | Quinoline-containing α-ketoamide cysteine and serine protease inhibitors |
| HK1039110A1 (zh) * | 1999-03-15 | 2002-04-12 | Axys Pharmaceuticals, Inc. | 以新颖的合成物及组分作为蛋白酶抑制剂 |
| WO2005000793A1 (ja) * | 2003-06-26 | 2005-01-06 | Taisho Pharmaceutical Co., Ltd. | ２位置換シクロアルキルカルボン酸誘導体 |
| EP1493739A1 (fr) * | 2003-07-03 | 2005-01-05 | Warner-Lambert Company LLC | Dérivés thiophényliques d'aminoacides, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
| AR055395A1 (es) * | 2005-08-26 | 2007-08-22 | Vertex Pharma | Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c |
| US7964624B1 (en) * | 2005-08-26 | 2011-06-21 | Vertex Pharmaceuticals Incorporated | Inhibitors of serine proteases |
| KR101578674B1 (ko) * | 2006-12-29 | 2015-12-18 | 아비에 도이치란트 게엠베하 운트 콤파니 카게 | 카복스아미드 화합물 및 칼페인 억제제로서의 이의 용도 |
| US9051304B2 (en) * | 2009-12-22 | 2015-06-09 | AbbVie Deutschland GmbH & Co. KG | Carboxamide compounds and their use as calpain inhibitors V |
| JP2017517475A (ja) * | 2014-02-19 | 2017-06-29 | エーテーハー チューリヒ | 化合物ライブラリーの製造方法 |
| CN109661229B (zh) * | 2016-06-29 | 2022-06-28 | 加利福尼亚大学董事会 | 用于治疗癌症的化合物和组合物 |
| BR112019006110A2 (pt) * | 2016-09-28 | 2019-09-10 | Blade Therapeutics Inc | moduladores de calpaína e usos terapêuticos dos mesmos |
| KR20200139721A (ko) * | 2018-03-28 | 2020-12-14 | 블레이드 테라퓨틱스, 인크. | 섬유성 질환을 치료하는 방법 |
-
2019
- 2019-03-21 CA CA3095164A patent/CA3095164A1/en active Pending
- 2019-03-21 EP EP19777469.8A patent/EP3774737A4/en not_active Withdrawn
- 2019-03-21 US US17/041,596 patent/US20210009564A1/en not_active Abandoned
- 2019-03-21 SG SG11202008750XA patent/SG11202008750XA/en unknown
- 2019-03-21 BR BR112020019560-0A patent/BR112020019560A2/pt not_active Application Discontinuation
- 2019-03-21 JP JP2020551973A patent/JP2021519312A/ja active Pending
- 2019-03-21 PE PE2020001468A patent/PE20212111A1/es unknown
- 2019-03-21 AU AU2019242387A patent/AU2019242387A1/en not_active Abandoned
- 2019-03-21 MX MX2020010033A patent/MX2020010033A/es unknown
- 2019-03-21 CN CN201980035887.9A patent/CN112204014A/zh active Pending
- 2019-03-21 KR KR1020207029538A patent/KR20200139702A/ko not_active Ceased
- 2019-03-21 RU RU2020130022A patent/RU2020130022A/ru unknown
- 2019-03-21 WO PCT/US2019/023457 patent/WO2019190885A1/en not_active Ceased
- 2019-03-28 AR ARP190100806A patent/AR115303A1/es not_active Application Discontinuation
- 2019-03-28 TW TW108111017A patent/TW202003472A/zh unknown
-
2020
- 2020-09-23 IL IL277548A patent/IL277548A/en unknown
- 2020-09-25 CL CL2020002496A patent/CL2020002496A1/es unknown
- 2020-09-25 PH PH12020551555A patent/PH12020551555A1/en unknown
- 2020-09-30 CO CONC2020/0012359A patent/CO2020012359A2/es unknown
- 2020-10-26 EC ECSENADI202068210A patent/ECSP20068210A/es unknown
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