JP2023544476A5 - - Google Patents
Info
- Publication number
- JP2023544476A5 JP2023544476A5 JP2023510342A JP2023510342A JP2023544476A5 JP 2023544476 A5 JP2023544476 A5 JP 2023544476A5 JP 2023510342 A JP2023510342 A JP 2023510342A JP 2023510342 A JP2023510342 A JP 2023510342A JP 2023544476 A5 JP2023544476 A5 JP 2023544476A5
- Authority
- JP
- Japan
- Prior art keywords
- alkyl
- cycloalkyl
- substituted
- compound according
- independently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNPCT/CN2020/108325 | 2020-08-11 | ||
| CN2020108325 | 2020-08-11 | ||
| PCT/IB2021/059266 WO2022034568A1 (en) | 2020-08-11 | 2021-10-09 | Triazole-pyridinyl substituted azacyclohexyl acetic acid compounds as lpa receptor antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2023544476A JP2023544476A (ja) | 2023-10-24 |
| JP2023544476A5 true JP2023544476A5 (https=) | 2024-10-11 |
Family
ID=78179477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2023510342A Pending JP2023544476A (ja) | 2020-08-11 | 2021-10-09 | Ｌｐａ受容体アンタゴニストとしてのトリアゾール－ピリジニル置換アザシクロヘキシル酢酸化合物 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP4196220A1 (https=) |
| JP (1) | JP2023544476A (https=) |
| KR (1) | KR20240068583A (https=) |
| CN (1) | CN116669727B (https=) |
| AU (1) | AU2021323515A1 (https=) |
| CA (1) | CA3191452A1 (https=) |
| IL (1) | IL300525A (https=) |
| MX (1) | MX2023001812A (https=) |
| WO (1) | WO2022034568A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4058144A1 (en) | 2019-11-15 | 2022-09-21 | Gilead Sciences, Inc. | Triazole carbamate pyridyl sulfonamides as lpa receptor antagonists and uses thereof |
| TWI843503B (zh) | 2020-06-03 | 2024-05-21 | 美商基利科學股份有限公司 | Lpa受體拮抗劑及其用途 |
| EP4161936A1 (en) | 2020-06-03 | 2023-04-12 | Gilead Sciences, Inc. | Lpa receptor antagonists and uses thereof |
| CN117751106A (zh) * | 2021-04-30 | 2024-03-22 | 唯久生物技术(苏州)有限公司 | 作为lpa拮抗剂的新型三唑-吡啶取代的吡咯烷基和四氢-2h-吡喃基乙酸化合物 |
| WO2022240879A1 (en) | 2021-05-11 | 2022-11-17 | Gilead Sciences, Inc. | Lpa receptor antagonists and uses thereof |
| KR20240007233A (ko) | 2021-05-13 | 2024-01-16 | 길리애드 사이언시즈, 인코포레이티드 | Lpa 수용체 길항제 및 이의 용도 |
| WO2023107938A1 (en) | 2021-12-08 | 2023-06-15 | Gilead Sciences, Inc. | Lpa receptor antagonists and uses thereof |
| TW202342017A (zh) | 2022-02-25 | 2023-11-01 | 美商洛子峰生物有限公司 | 用於治療與ｌｐａ受體活性相關的病狀的化合物及組合物 |
| TW202417426A (zh) * | 2022-07-25 | 2024-05-01 | 大陸商武漢人福創新藥物研發中心有限公司 | 三氮唑類化合物及其作為lpar1拮抗劑的用途 |
| WO2025051266A1 (zh) * | 2023-09-08 | 2025-03-13 | 西藏海思科制药有限公司 | 杂芳环衍生物的lpar1拮抗剂及其用途 |
| WO2025162421A1 (zh) * | 2024-02-04 | 2025-08-07 | 西藏海思科制药有限公司 | Lpar1拮抗剂及其用途 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002062389A1 (en) * | 2001-02-08 | 2002-08-15 | Ono Pharmaceutical Co., Ltd. | Remedies for urinary diseases comprising lpa receptor controlling agents |
| GB2466121B (en) * | 2008-12-15 | 2010-12-08 | Amira Pharmaceuticals Inc | Antagonists of lysophosphatidic acid receptors |
| CN102459627B (zh) * | 2009-06-16 | 2015-07-29 | 纳幕尔杜邦公司 | 通过酰基-辅酶A溶血磷脂酰基转移酶的表达对长链ω-3和ω-6多不饱和脂肪酸的生物合成的改善 |
| US8785442B2 (en) * | 2011-01-30 | 2014-07-22 | Curegenix, Inc. | Compound as antagonist of lysophosphatidic acid receptor, composition, and use thereof |
| WO2012138648A1 (en) * | 2011-04-06 | 2012-10-11 | Irm Llc | Compositions and methods for modulating lpa receptors |
| EP2922823B1 (en) | 2012-11-20 | 2018-10-31 | Merck Sharp & Dohme Corp. | Pyrimidine pde10 inhibitors |
| US20140200215A1 (en) * | 2013-01-15 | 2014-07-17 | Intermune, Inc. | Lysophosphatidic acid receptor antagonists |
| WO2014145873A2 (en) * | 2013-03-15 | 2014-09-18 | Epigen Biosciences, Inc. | Heterocyclic compounds useful in the treatment of disease |
| CN111712492B (zh) * | 2017-12-19 | 2024-05-31 | 百时美施贵宝公司 | 作为lpa拮抗剂的环己基酸三唑唑类 |
| US11261180B2 (en) * | 2017-12-19 | 2022-03-01 | Bristol-Myers Squibb Company | Cyclohexyl acid isoxazole azoles as LPA antagonists |
| CN112041302B (zh) * | 2017-12-19 | 2024-11-19 | 百时美施贵宝公司 | 作为lpa拮抗剂的吡唑o-连接的氨基甲酰基环己基酸 |
| JP7208240B2 (ja) * | 2017-12-19 | 2023-01-18 | ブリストル－マイヤーズ スクイブ カンパニー | Ｌｐａアンタゴニストとしてのシクロヘキシル酸トリアゾールアジン |
| ES2946657T3 (es) * | 2018-09-18 | 2023-07-24 | Bristol Myers Squibb Co | Acidos ciclopentílicos como antagonistas de LPA |
-
2021
- 2021-10-09 WO PCT/IB2021/059266 patent/WO2022034568A1/en not_active Ceased
- 2021-10-09 EP EP21791479.5A patent/EP4196220A1/en active Pending
- 2021-10-09 CA CA3191452A patent/CA3191452A1/en active Pending
- 2021-10-09 MX MX2023001812A patent/MX2023001812A/es unknown
- 2021-10-09 AU AU2021323515A patent/AU2021323515A1/en active Pending
- 2021-10-09 IL IL300525A patent/IL300525A/en unknown
- 2021-10-09 KR KR1020237008152A patent/KR20240068583A/ko active Pending
- 2021-10-09 CN CN202180067597.XA patent/CN116669727B/zh active Active
- 2021-10-09 JP JP2023510342A patent/JP2023544476A/ja active Pending
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