JP2022500470A5 - - Google Patents
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- Publication number
- JP2022500470A5 JP2022500470A5 JP2021515030A JP2021515030A JP2022500470A5 JP 2022500470 A5 JP2022500470 A5 JP 2022500470A5 JP 2021515030 A JP2021515030 A JP 2021515030A JP 2021515030 A JP2021515030 A JP 2021515030A JP 2022500470 A5 JP2022500470 A5 JP 2022500470A5
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862732590P | 2018-09-18 | 2018-09-18 | |
| US62/732,590 | 2018-09-18 | ||
| PCT/US2019/051274 WO2020060915A1 (en) | 2018-09-18 | 2019-09-16 | Cyclopentyl acids as lpa antagonists |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022500470A JP2022500470A (ja) | 2022-01-04 |
| JP2022500470A5 true JP2022500470A5 (https=) | 2023-11-08 |
| JPWO2020060915A5 JPWO2020060915A5 (https=) | 2023-11-08 |
| JP7427658B2 JP7427658B2 (ja) | 2024-02-05 |
Family
ID=68073223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021515030A Active JP7427658B2 (ja) | 2018-09-18 | 2019-09-16 | Ｌｐａアンタゴニストとしてのシクロペンチル酸 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US12209072B2 (https=) |
| EP (1) | EP3852746B1 (https=) |
| JP (1) | JP7427658B2 (https=) |
| KR (1) | KR102950123B1 (https=) |
| CN (1) | CN113473985A (https=) |
| ES (1) | ES2946657T3 (https=) |
| WO (1) | WO2020060915A1 (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20220041572A1 (en) * | 2018-09-18 | 2022-02-10 | Bristol-Myers Squibb Company | Cycloheptyl acids as lpa antagonists |
| KR102788997B1 (ko) | 2018-09-18 | 2025-03-28 | 브리스톨-마이어스 스큅 컴퍼니 | Lpa 길항제로서의 옥사비시클로 산 |
| CN111434655A (zh) * | 2019-01-15 | 2020-07-21 | 武汉朗来科技发展有限公司 | 溶血磷脂酸受体拮抗剂及其制备方法 |
| AU2020256166A1 (en) | 2019-04-02 | 2021-10-14 | Aligos Therapeutics, Inc. | Compounds targeting PRMT5 |
| AU2020384883B2 (en) | 2019-11-15 | 2023-11-16 | Gilead Sciences, Inc. | Triazole carbamate pyridyl sulfonamides as LPA receptor antagonists and uses thereof |
| TWI843503B (zh) | 2020-06-03 | 2024-05-21 | 美商基利科學股份有限公司 | Lpa受體拮抗劑及其用途 |
| CN115867556B (zh) * | 2020-06-03 | 2025-05-06 | 吉利德科学公司 | Lpa受体拮抗剂及其用途 |
| EP4196220A1 (en) * | 2020-08-11 | 2023-06-21 | Viva Star Biosciences Limited | Triazole-pyridinyl substituted azacyclohexyl acetic acid compounds as lpa receptor antagonists |
| EP4330249A1 (en) * | 2021-04-30 | 2024-03-06 | Viva Star Biosciences (Suzhou) Co., Ltd. | Novel triazole-pyridine substituted pyrrolidinyl and tetrahydro-2h-pyranyl acetic acid compounds as lpa antagonists |
| TWI853704B (zh) * | 2021-05-11 | 2024-08-21 | 美商基利科學股份有限公司 | Lpa受體拮抗劑及其用途 |
| KR20240007233A (ko) | 2021-05-13 | 2024-01-16 | 길리애드 사이언시즈, 인코포레이티드 | Lpa 수용체 길항제 및 이의 용도 |
| CA3224635A1 (en) * | 2021-07-20 | 2023-01-26 | Yunfei Li | Lpa1 small molecule antagonist |
| WO2023107938A1 (en) | 2021-12-08 | 2023-06-15 | Gilead Sciences, Inc. | Lpa receptor antagonists and uses thereof |
| AR128613A1 (es) | 2022-02-25 | 2024-05-29 | Lhotse Bio Inc | Compuestos y composiciones para el tratamiento de afecciones asociadas con la actividad del receptor de lpa |
| CN120530099A (zh) * | 2023-01-19 | 2025-08-22 | 江苏恒瑞医药股份有限公司 | 一种三氮唑类化合物的可药用盐、晶型及其制备方法 |
| CN121866249A (zh) * | 2023-09-08 | 2026-04-14 | 海思科医药集团股份有限公司 | 一种lpar1拮抗剂及其用途 |
| WO2026061483A1 (zh) * | 2024-09-19 | 2026-03-26 | 西藏海思科制药有限公司 | 一种lpar1拮抗剂及其用途 |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002062389A1 (en) | 2001-02-08 | 2002-08-15 | Ono Pharmaceutical Co., Ltd. | Remedies for urinary diseases comprising lpa receptor controlling agents |
| US20080186971A1 (en) | 2007-02-02 | 2008-08-07 | Tarari, Inc. | Systems and methods for processing access control lists (acls) in network switches using regular expression matching logic |
| GB2470833B (en) | 2009-06-03 | 2011-06-01 | Amira Pharmaceuticals Inc | Polycyclic antagonists of lysophosphatidic acid receptors |
| WO2011017350A2 (en) | 2009-08-04 | 2011-02-10 | Amira Pharmaceuticals, Inc. | Compounds as lysophosphatidic acid receptor antagonists |
| GB2474748B (en) | 2009-10-01 | 2011-10-12 | Amira Pharmaceuticals Inc | Polycyclic compounds as lysophosphatidic acid receptor antagonists |
| GB2474120B (en) | 2009-10-01 | 2011-12-21 | Amira Pharmaceuticals Inc | Compounds as Lysophosphatidic acid receptor antagonists |
| TW201120016A (en) | 2009-12-08 | 2011-06-16 | Abbott Lab | Novel oxadiazole compounds |
| EA201390821A1 (ru) | 2010-12-07 | 2013-10-30 | Амира Фармасьютикалс, Инк. | Антагонисты рецепторов лизофосфатидной кислоты и их применение |
| EP3360552A1 (en) | 2010-12-07 | 2018-08-15 | Amira Pharmaceuticals, Inc. | Polycyclic lpa1 antagonist and uses thereof |
| EP2694472B1 (en) | 2011-04-05 | 2020-03-11 | Takeda Pharmaceutical Company Limited | Sulfonamide derivative and use thereof |
| WO2012138648A1 (en) | 2011-04-06 | 2012-10-11 | Irm Llc | Compositions and methods for modulating lpa receptors |
| WO2013070879A1 (en) | 2011-11-10 | 2013-05-16 | Bristol-Myers Squibb Company | Methods for treating spinal cord injury with lpa receptor antagonists |
| SG11201407228PA (en) | 2012-06-20 | 2014-12-30 | Hoffmann La Roche | N-aryltriazole compounds as lpar antagonists |
| UA109868C2 (ru) * | 2012-06-20 | 2015-10-12 | Ф. Хоффманн-Ля Рош Аг | Соединения n-алкилтриазола как антагонисты лизофосфатидной кислоты (lpar) |
| EP3010908A1 (en) * | 2013-02-20 | 2016-04-27 | E. I. du Pont de Nemours and Company | Fungicidal pyrazoles |
| US8962660B2 (en) | 2013-03-14 | 2015-02-24 | Bristol-Myers Squibb Company | Oxabicyclo [2.2.2] acid GPR120 modulators |
| DK2988743T3 (da) | 2013-03-15 | 2021-03-01 | Epigen Biosciences Inc | Heterocykliske forbindelser, der kan anvendes til behandling af sygdom |
| JP2017095366A (ja) | 2015-11-18 | 2017-06-01 | 持田製薬株式会社 | 新規ビアリールアミド誘導体 |
| AR108838A1 (es) | 2016-06-21 | 2018-10-03 | Bristol Myers Squibb Co | Ácidos de carbamoiloximetil triazol ciclohexilo como antagonistas de lpa |
| US11447475B2 (en) | 2017-12-19 | 2022-09-20 | Bristol-Myers Squibb Company | Isoxazole N-linked carbamoyl cyclohexyl acids as LPA antagonists |
| EP4011875A1 (en) | 2017-12-19 | 2022-06-15 | Bristol-Myers Squibb Company | Triazole n-linked carbamoyl cyclohexyl acids as lpa antagonists |
| WO2019126089A1 (en) | 2017-12-19 | 2019-06-27 | Bristol-Myers Squibb Company | Cyclohexyl acid pyrazole azines as lpa antagonists |
| US11180488B2 (en) | 2017-12-19 | 2021-11-23 | Bristol-Myers Squibb Company | Isoxazole o-linked carbamoyl cyclohexyl acids as LPA antagonists |
| JP7212047B2 (ja) | 2017-12-19 | 2023-01-24 | ブリストル－マイヤーズ スクイブ カンパニー | Ｌｐａアンタゴニストとしてのシクロヘキシル酸ピラゾールアゾール |
| EP3728209B1 (en) | 2017-12-19 | 2025-12-24 | Bristol-Myers Squibb Company | Cyclohexyl acid isoxazole azines as lpa antagonists |
| CN111699180B (zh) | 2017-12-19 | 2024-11-29 | 百时美施贵宝公司 | 作为lpa拮抗剂的吡唑n-连接的氨基甲酰基环己基酸 |
| KR102756639B1 (ko) | 2017-12-19 | 2025-01-16 | 브리스톨-마이어스 스큅 컴퍼니 | Lpa 길항제로서의 시클로헥실 산 이속사졸 아졸 |
| CN112041302B (zh) | 2017-12-19 | 2024-11-19 | 百时美施贵宝公司 | 作为lpa拮抗剂的吡唑o-连接的氨基甲酰基环己基酸 |
| US20220041572A1 (en) * | 2018-09-18 | 2022-02-10 | Bristol-Myers Squibb Company | Cycloheptyl acids as lpa antagonists |
| KR102788997B1 (ko) * | 2018-09-18 | 2025-03-28 | 브리스톨-마이어스 스큅 컴퍼니 | Lpa 길항제로서의 옥사비시클로 산 |
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2019
- 2019-09-16 ES ES19779299T patent/ES2946657T3/es active Active
- 2019-09-16 EP EP19779299.7A patent/EP3852746B1/en active Active
- 2019-09-16 WO PCT/US2019/051274 patent/WO2020060915A1/en not_active Ceased
- 2019-09-16 KR KR1020217011087A patent/KR102950123B1/ko active Active
- 2019-09-16 JP JP2021515030A patent/JP7427658B2/ja active Active
- 2019-09-16 US US17/276,176 patent/US12209072B2/en active Active
- 2019-09-16 CN CN201980074355.6A patent/CN113473985A/zh active Pending