|
US3906092A
(en)
|
1971-11-26 |
1975-09-16 |
Merck & Co Inc |
Stimulation of antibody response
|
|
US4415732A
(en)
|
1981-03-27 |
1983-11-15 |
University Patents, Inc. |
Phosphoramidite compounds and processes
|
|
US4373071A
(en)
|
1981-04-30 |
1983-02-08 |
City Of Hope Research Institute |
Solid-phase synthesis of polynucleotides
|
|
US4401796A
(en)
|
1981-04-30 |
1983-08-30 |
City Of Hope Research Institute |
Solid-phase synthesis of polynucleotides
|
|
DE3314999A1
(de)
|
1983-04-26 |
1985-03-14 |
Behringwerke Ag, 3550 Marburg |
Verwendung des diterpen-derivates forskolin zur immunstimulation
|
|
US5663163A
(en)
|
1987-09-07 |
1997-09-02 |
Fujisawa Pharmaceutical Co., Ltd. |
Cephem compounds and processes for preparation thereof
|
|
CA1320446C
(en)
|
1988-06-20 |
1993-07-20 |
William A. Carter |
Modulation of lymphokine-resistant cellular states by dsrnas
|
|
JP3150967B2
(ja)
|
1989-10-11 |
2001-03-26 |
エイチイーエム リサーチ，インコーポレイティド |
二本鎖ｒｎａによる損傷に続くショックからの保護
|
|
DE69400208T2
(de)
|
1993-01-25 |
1996-11-28 |
Hybridon Inc |
Olionukleotidalkylphosphonate und -phosphonothioate
|
|
EP0683668A4
(en)
|
1993-01-27 |
1997-12-29 |
Affymax Tech Nv |
PREPARATIONS AND METHODS FOR TRANSDERMAL DRUG ADMINISTRATION.
|
|
US5516652A
(en)
|
1993-10-06 |
1996-05-14 |
Merck Frosst Canada Inc. |
DNA encoding prostaglandin receptor IP
|
|
CA2184375C
(en)
|
1994-03-18 |
2006-05-02 |
Sergei M. Gryaznov |
Oligonucleotide n3'-p5' phosphoramidates: synthesis and compounds; hybridization and nuclease resistance properties
|
|
WO1995026204A1
(en)
|
1994-03-25 |
1995-10-05 |
Isis Pharmaceuticals, Inc. |
Immune stimulation by phosphorothioate oligonucleotide analogs
|
|
US5874560A
(en)
|
1994-04-22 |
1999-02-23 |
The United States Of America As Represented By The Department Of Health And Human Services |
Melanoma antigens and their use in diagnostic and therapeutic methods
|
|
CA2194761C
(en)
|
1994-07-15 |
2006-12-19 |
Arthur M. Krieg |
Immunomodulatory oligonucleotides
|
|
US6239116B1
(en)
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US5795587A
(en)
|
1995-01-23 |
1998-08-18 |
University Of Pittsburgh |
Stable lipid-comprising drug delivery complexes and methods for their production
|
|
US7148205B2
(en)
|
1995-12-13 |
2006-12-12 |
Mirus Bio Corporation |
Intravascular delivery of non-viral nucleic acid
|
|
US6689757B1
(en)
|
1996-02-12 |
2004-02-10 |
M.L. Laboratories Plc |
Methods for vaccination and vaccines therefor
|
|
US6090391A
(en)
|
1996-02-23 |
2000-07-18 |
Aviron |
Recombinant tryptophan mutants of influenza
|
|
EP0912724B1
(en)
*
|
1996-07-15 |
2009-12-09 |
The Government of The United States of America, as represented by The Department of Health and Human Services |
Production of attenuated respiratory syncytial virus vaccines from cloned nucleotide sequences
|
|
ATE292980T1
(de)
|
1996-10-11 |
2005-04-15 |
Univ California |
Immunostimulierende oligonucleotidekonjugate
|
|
EP0839912A1
(en)
|
1996-10-30 |
1998-05-06 |
Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) |
Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
|
|
GB9623051D0
(en)
|
1996-11-06 |
1997-01-08 |
Schacht Etienne H |
Delivery of DNA to target cells in biological systems
|
|
EP0855184A1
(en)
|
1997-01-23 |
1998-07-29 |
Grayson B. Dr. Lipford |
Pharmaceutical composition comprising a polynucleotide and an antigen especially for vaccination
|
|
US6406705B1
(en)
|
1997-03-10 |
2002-06-18 |
University Of Iowa Research Foundation |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
|
WO1998047913A2
(en)
|
1997-04-18 |
1998-10-29 |
The University Of Medicine And Dentistry Of New Jersey |
Inhibition of hiv-1 replication by a tat rna-binding domain peptide analog
|
|
US6589940B1
(en)
|
1997-06-06 |
2003-07-08 |
Dynavax Technologies Corporation |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
|
CA2291483C
(en)
|
1997-06-06 |
2012-09-18 |
Dynavax Technologies Corporation |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
|
EP1374894A3
(en)
|
1997-06-06 |
2004-09-22 |
Dynavax Technologies Corporation |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
|
US20040006034A1
(en)
|
1998-06-05 |
2004-01-08 |
Eyal Raz |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
|
EP1009413B1
(en)
|
1997-09-05 |
2007-02-14 |
The Regents Of The University Of California |
Use of immunostimulatory oligonucleotides for preventing or treating asthma
|
|
US6096307A
(en)
|
1997-12-11 |
2000-08-01 |
A. Glenn Braswell |
Compositions for immunostimulation containing Echinacea angustofolia, bromelain, and lysozyme
|
|
ES2284247T3
(es)
|
1998-04-03 |
2007-11-01 |
University Of Iowa Research Foundation |
Metodos y productos para estimular el sistema inmunitario usando oligonucleotidos y citoquinas inmunoterapeuticos.
|
|
WO1999053961A1
(en)
|
1998-04-23 |
1999-10-28 |
The Regents Of The University Of Michigan |
Peptides for efficient gene transfer
|
|
WO2000075304A1
(fr)
|
1999-06-08 |
2000-12-14 |
Aventis Pasteur |
Oligonucleotide immunostimulant
|
|
CA2312385A1
(en)
|
1999-06-22 |
2000-12-22 |
Daiso Co., Ltd. |
Process for producing erythro-3-amino-2-hydroxybutyric acid derivatives
|
|
US6514948B1
(en)
|
1999-07-02 |
2003-02-04 |
The Regents Of The University Of California |
Method for enhancing an immune response
|
|
WO2001004135A2
(en)
|
1999-07-13 |
2001-01-18 |
The Regents Of The University Of Michigan |
Crosslinked dna condensate compositions and gene delivery methods
|
|
US20030104622A1
(en)
|
1999-09-01 |
2003-06-05 |
Robbins Paul D. |
Identification of peptides that facilitate uptake and cytoplasmic and/or nuclear transport of proteins, DNA and viruses
|
|
EP1619254B1
(en)
|
1999-09-09 |
2010-12-22 |
CureVac GmbH |
Transfer of mRNA using polycationic compounds
|
|
AT409085B
(de)
|
2000-01-28 |
2002-05-27 |
Cistem Biotechnologies Gmbh |
Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen
|
|
US6552006B2
(en)
|
2000-01-31 |
2003-04-22 |
The Regents Of The University Of California |
Immunomodulatory polynucleotides in treatment of an infection by an intracellular pathogen
|
|
WO2001075164A2
(en)
|
2000-03-30 |
2001-10-11 |
Whitehead Institute For Biomedical Research |
Rna sequence-specific mediators of rna interference
|
|
EP1292331A2
(en)
|
2000-06-07 |
2003-03-19 |
Biosynexus Incorporated |
Immunostimulatory rna/dna hybrid molecules
|
|
WO2001097843A2
(en)
|
2000-06-22 |
2001-12-27 |
University Of Iowa Research Foundation |
Methods for enhancing antibody-induced cell lysis and treating cancer
|
|
CN1298738C
(zh)
|
2000-06-23 |
2007-02-07 |
惠氏控股有限公司 |
修饰的麻疹病毒v蛋白
|
|
US6376704B1
(en)
|
2000-06-28 |
2002-04-23 |
3M Innovative Properties Company |
Naphthyoxyalkyl(meth)acrylates with high refractive indices and low glass transition temperatures
|
|
US6716434B1
(en)
|
2000-09-19 |
2004-04-06 |
Daniel R. Ansley |
Composition and method for immunostimulation in non- mammalian vertebrates
|
|
GB0025577D0
(en)
|
2000-10-18 |
2000-12-06 |
Smithkline Beecham Biolog |
Vaccine
|
|
US7371387B2
(en)
|
2001-02-21 |
2008-05-13 |
Genitrix Llc |
Vaccine compositions and methods of modulating immune responses
|
|
EP1383924B1
(en)
|
2001-04-02 |
2010-02-10 |
University of South Florida |
Lps-responsive chs1/beige-like anchor gene and therapeutic applications thereof
|
|
ATE376434T1
(de)
|
2001-04-21 |
2007-11-15 |
Curevac Gmbh |
Injektionsgerät für mrna applikation
|
|
ES2340532T3
(es)
|
2001-06-05 |
2010-06-04 |
Curevac Gmbh |
Arnm con un contenido g/c aumentado que codifica para un antigeno bacteriano y utilizacion del mismo.
|
|
US7785610B2
(en)
|
2001-06-21 |
2010-08-31 |
Dynavax Technologies Corporation |
Chimeric immunomodulatory compounds and methods of using the same—III
|
|
US20060029655A1
(en)
|
2001-06-25 |
2006-02-09 |
Yissum Research Development Company Of The Hebrew University Of Jerusalem |
Method for preparation of vesicles loaded with biological material and different uses thereof
|
|
AR045702A1
(es)
|
2001-10-03 |
2005-11-09 |
Chiron Corp |
Composiciones de adyuvantes.
|
|
DE10148886A1
(de)
|
2001-10-04 |
2003-04-30 |
Avontec Gmbh |
Inhibition von STAT-1
|
|
US7276489B2
(en)
|
2002-10-24 |
2007-10-02 |
Idera Pharmaceuticals, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5′ ends
|
|
WO2003035836A2
(en)
|
2001-10-24 |
2003-05-01 |
Hybridon Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5' ends
|
|
DE10162480A1
(de)
|
2001-12-19 |
2003-08-07 |
Ingmar Hoerr |
Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen
|
|
AU2003235707A1
(en)
|
2002-01-18 |
2003-07-30 |
Curevac Gmbh |
Immunogenic preparations and vaccines on the basis of mrna
|
|
US7741297B2
(en)
|
2002-02-04 |
2010-06-22 |
Oncothyreon Inc. |
Immunostimulatory, covalently lipidated oligonucleotides
|
|
ES2339934T3
(es)
|
2002-03-01 |
2010-05-27 |
The Administrators Of The Tulane Educational Fund |
Conjugados de agentes citotoxicos y peptidos biologicamente activos.
|
|
EP3006043B1
(en)
|
2002-04-04 |
2019-05-29 |
Zoetis Belgium S.A. |
Immunostimulatory g,u-containing oligoribonucleotides
|
|
JP2005538697A
(ja)
|
2002-04-19 |
2005-12-22 |
シエーリング アクチエンゲゼルシャフト |
新規前立腺腫瘍特異的プロモーター
|
|
DE10229872A1
(de)
|
2002-07-03 |
2004-01-29 |
Curevac Gmbh |
Immunstimulation durch chemisch modifizierte RNA
|
|
EP1393745A1
(en)
|
2002-07-29 |
2004-03-03 |
Hybridon, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by optimal presentation of 5'ends
|
|
US7625872B2
(en)
|
2002-12-23 |
2009-12-01 |
Dynavax Technologies Corporation |
Branched immunomodulatory compounds and methods of using the same
|
|
WO2004064782A2
(en)
|
2003-01-16 |
2004-08-05 |
Hybridon, Inc. |
Modulation of immunostimulatory properties of oligonucleotide-based compounds by utilizing modified immunostimulatory dinucleotides
|
|
US9068234B2
(en)
|
2003-01-21 |
2015-06-30 |
Ptc Therapeutics, Inc. |
Methods and agents for screening for compounds capable of modulating gene expression
|
|
US8969543B2
(en)
|
2003-04-03 |
2015-03-03 |
Bioneer Corporation |
SiRNA-hydrophilic polymer conjugates for intracellular delivery of siRNA and method thereof
|
|
CA2522213A1
(en)
|
2003-04-08 |
2004-10-28 |
Dante J. Marciani |
Semi-synthetic saponin analogs with carrier and immune stimulatory activities for dna and rna vaccines
|
|
AU2004252409A1
(en)
|
2003-04-10 |
2005-01-06 |
3M Innovative Properties Company |
Methods and compositions for enhancing immune response
|
|
ES2308200T3
(es)
|
2003-06-30 |
2008-12-01 |
Universite De Lausanne |
Peptido derivado de rasgap para destruir selectivamente celulas cancerosas.
|
|
AU2004255470B2
(en)
|
2003-07-10 |
2010-08-19 |
Cytos Biotechnology Ag |
Packaged virus-like particles
|
|
DE10335833A1
(de)
|
2003-08-05 |
2005-03-03 |
Curevac Gmbh |
Transfektion von Blutzellen mit mRNA zur Immunstimulation und Gentherapie
|
|
AU2004276226B2
(en)
|
2003-08-05 |
2009-07-30 |
Avi Biopharma, Inc. |
Oligonucleotide analog and method for treating flavivirus infections
|
|
GB0321615D0
(en)
|
2003-09-15 |
2003-10-15 |
Glaxo Group Ltd |
Improvements in vaccination
|
|
AU2004275876B2
(en)
|
2003-09-25 |
2011-03-31 |
Coley Pharmaceutical Gmbh |
Nucleic acid-lipophilic conjugates
|
|
DE10346721A1
(de)
|
2003-10-08 |
2005-05-04 |
Holger Kalthoff |
Oligonukleotide, diese enthaltende Mittel und deren Verwendung
|
|
WO2005035549A2
(en)
|
2003-10-14 |
2005-04-21 |
Kernel Biopharma Inc. |
Amiphiphylic peptide-pna conjugates for the delivery of pna through the blood brain barrier
|
|
US20050214318A1
(en)
|
2003-10-23 |
2005-09-29 |
Nmk Research, Llc |
Immunogenic composition and method of developing a vaccine based on fusion protein
|
|
US20050215501A1
(en)
|
2003-10-24 |
2005-09-29 |
Coley Pharmaceutical Group, Inc. |
Methods and products for enhancing epitope spreading
|
|
KR101138131B1
(ko)
|
2003-12-08 |
2012-04-23 |
이데라 파마슈티칼즈, 인코포레이티드 |
작은 올리고뉴클레오티드-기초 화합물에 의한 면역자극특성의 조절
|
|
EP1704160B1
(en)
|
2003-12-22 |
2010-11-10 |
The Trustees of The University of Pennsylvania |
Methods and compositions for identifying rna-binding proteins
|
|
EP1720568A2
(en)
|
2004-02-19 |
2006-11-15 |
Coley Pharmaceutical Group, Inc. |
Immunostimulatory viral rna oligonucleotides
|
|
CA2567789A1
(en)
|
2004-06-08 |
2006-08-03 |
Coley Pharmaceutical Gmbh |
Abasic oligonucleotide as carrier platform for antigen and immunostimulatory agonist and antagonist
|
|
WO2006046978A2
(en)
|
2004-06-28 |
2006-05-04 |
Argos Therapeutics, Inc. |
Cationic peptide-mediated transformation
|
|
DE102004035227A1
(de)
|
2004-07-21 |
2006-02-16 |
Curevac Gmbh |
mRNA-Gemisch zur Vakzinierung gegen Tumorerkrankungen
|
|
WO2006015789A2
(de)
*
|
2004-08-03 |
2006-02-16 |
Geneart Ag |
Verfahren zur modulation der genexpression durch änderung des cpg gehalts
|
|
DE102004042546A1
(de)
|
2004-09-02 |
2006-03-09 |
Curevac Gmbh |
Kombinationstherapie zur Immunstimulation
|
|
US20080193468A1
(en)
|
2004-09-08 |
2008-08-14 |
Children's Medical Center Corporation |
Method for Stimulating the Immune Response of Newborns
|
|
TW200636064A
(en)
*
|
2004-10-28 |
2006-10-16 |
Centocor Inc |
Anti-respiratory syncytial virus antibodies, antigens and uses thereof
|
|
CA2593032C
(en)
|
2004-12-27 |
2015-12-22 |
Silence Therapeutics Ag |
Coated lipid complexes and their use
|
|
CN101198353A
(zh)
|
2005-04-14 |
2008-06-11 |
昆士兰大学 |
免疫调节组合物和其应用
|
|
WO2006116458A2
(en)
|
2005-04-26 |
2006-11-02 |
Coley Pharmaceutical Gmbh |
Modified oligoribonucleotide analogs with enhances immunostimulatory activity
|
|
DE102005023170A1
(de)
|
2005-05-19 |
2006-11-23 |
Curevac Gmbh |
Optimierte Formulierung für mRNA
|
|
US9505867B2
(en)
|
2005-05-31 |
2016-11-29 |
Ecole Polytechmique Fédérale De Lausanne |
Triblock copolymers for cytoplasmic delivery of gene-based drugs
|
|
WO2007031322A1
(en)
|
2005-09-14 |
2007-03-22 |
Gunther Hartmann |
Compositions comprising immunostimulatory rna oligonucleotides and methods for producing said rna oligonucleotides
|
|
EP1764107A1
(en)
|
2005-09-14 |
2007-03-21 |
Gunther Hartmann |
Compositions comprising immunostimulatory RNA oligonucleotides and methods for producing said RNA oligonucleotides
|
|
EA200801045A1
(ru)
|
2005-10-12 |
2008-10-30 |
Кэнсер Рисерч Текнолоджи Лтд. |
Способы и композиции для лечения иммунных нарушений
|
|
EP1948674A4
(en)
|
2005-11-02 |
2009-02-04 |
Protiva Biotherapeutics Inc |
MODIFIED SIRNA MOLECULES AND APPLICATIONS THEREOF
|
|
US7470674B2
(en)
|
2005-11-07 |
2008-12-30 |
Idera Pharmaceuticals, Inc. |
Immunostimulatory properties of oligonucleotide-based compounds comprising modified immunostimulatory dinucleotides
|
|
KR20080072934A
(ko)
|
2005-11-25 |
2008-08-07 |
콜리 파마슈티칼 게엠베하 |
면역자극성 올리고리보뉴클레오티드
|
|
US9687262B2
(en)
|
2005-11-30 |
2017-06-27 |
CARDINAL HEALTH SWITZERLAND 515 GmbH |
Methods and devices for treating vulnerable plaque
|
|
CA2633063A1
(en)
|
2005-12-16 |
2007-06-21 |
Diatos |
Cell penetrating peptide conjugates for delivering of nucleic acids intocells
|
|
US20090081157A1
(en)
|
2006-01-09 |
2009-03-26 |
Richard Syd Kornbluth |
Immunostimulatory Combinations for Vaccine Adjuvants
|
|
DE102006007433A1
(de)
|
2006-02-17 |
2007-08-23 |
Curevac Gmbh |
Adjuvanz in Form einer Lipid-modifizierten Nukleinsäure
|
|
US8859233B2
(en)
|
2006-05-02 |
2014-10-14 |
Carviar Aps |
Method for immunizing an avian species
|
|
DE102006035618A1
(de)
|
2006-07-31 |
2008-02-07 |
Curevac Gmbh |
Nukleinsäure der Formel (I): GlXmGn, insbesondere als immunstimulierendes Adjuvanz
|
|
AU2007280690C1
(en)
|
2006-07-31 |
2012-08-23 |
Curevac Gmbh |
Nucleic acid of formula (I): GIXmGn, or (II): CIXmCn, in particular as an immune-stimulating agent/adjuvant
|
|
CA2661093A1
(en)
|
2006-08-18 |
2008-02-21 |
Nastech Pharmaceutical Company Inc. |
Dicer substrate rna peptide conjugates and methods for rna therapeutics
|
|
EP1911844A1
(en)
|
2006-10-10 |
2008-04-16 |
Qiagen GmbH |
Methods and kit for isolating nucleic acids
|
|
DE102006051516A1
(de)
|
2006-10-31 |
2008-05-08 |
Curevac Gmbh |
(Basen-)modifizierte RNA zur Expressionssteigerung eines Proteins
|
|
DE102006061015A1
(de)
|
2006-12-22 |
2008-06-26 |
Curevac Gmbh |
Verfahren zur Reinigung von RNA im präparativen Maßstab mittels HPLC
|
|
DE102007001370A1
(de)
|
2007-01-09 |
2008-07-10 |
Curevac Gmbh |
RNA-kodierte Antikörper
|
|
CA2695385A1
(en)
|
2007-07-31 |
2009-02-05 |
Atul Bedi |
Polypeptide-nucleic acid conjugate for immunoprophylaxis or immunotherapy for neoplastic or infectious disorders
|
|
WO2009030254A1
(en)
|
2007-09-04 |
2009-03-12 |
Curevac Gmbh |
Complexes of rna and cationic peptides for transfection and for immunostimulation
|
|
WO2009046739A1
(en)
|
2007-10-09 |
2009-04-16 |
Curevac Gmbh |
Composition for treating prostate cancer (pca)
|
|
WO2009046738A1
(en)
|
2007-10-09 |
2009-04-16 |
Curevac Gmbh |
Composition for treating lung cancer, particularly of non-small lung cancers (nsclc)
|
|
WO2009053700A1
(en)
|
2007-10-23 |
2009-04-30 |
Cancer Research Technology Limited |
Modification of nucleic acid-containing biological entities
|
|
WO2009086640A1
(en)
|
2008-01-10 |
2009-07-16 |
Nventa Biopharmaceuticals Corporation |
Adjuvant compositions comprising poly-ic and a cationic polymer
|
|
CA2710534C
(en)
*
|
2008-01-31 |
2018-09-04 |
Curevac Gmbh |
Nucleic acids of formula (i) (nuglxmgnnv)a and derivatives thereof as an immunostimulating agent/adjuvant
|
|
WO2009127230A1
(en)
|
2008-04-16 |
2009-10-22 |
Curevac Gmbh |
MODIFIED (m)RNA FOR SUPPRESSING OR AVOIDING AN IMMUNOSTIMULATORY RESPONSE AND IMMUNOSUPPRESSIVE COMPOSITION
|
|
EP2306993B1
(en)
|
2008-05-26 |
2014-03-12 |
Universität Zürich |
Protamine/rna nanoparticles for immunostimulation
|
|
US20110159023A1
(en)
|
2008-08-25 |
2011-06-30 |
Solomon Langermann |
Pd-1 antagonists and methods for treating infectious disease
|
|
WO2010037408A1
(en)
|
2008-09-30 |
2010-04-08 |
Curevac Gmbh |
Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
|
|
WO2010067041A1
(en)
|
2008-12-11 |
2010-06-17 |
Hybrid Biosystems Limited |
Modification of nucleic acid vectors with polymers comprising charged quaternary amino groups
|
|
WO2010088927A1
(en)
|
2009-02-09 |
2010-08-12 |
Curevac Gmbh |
Use of pei for the improvement of endosomal release and expression of transfected nucleic acids, complexed with cationic or polycationic compounds
|
|
CA2768598A1
(en)
|
2009-07-22 |
2011-01-27 |
Cenix Bioscience Gmbh |
Delivery system and conjugates for compound delivery via naturally occurring intracellular transport routes
|
|
WO2011011631A2
(en)
|
2009-07-22 |
2011-01-27 |
Samuel Zalipsky |
Nucleic acid delivery vehicles
|
|
US20110053829A1
(en)
|
2009-09-03 |
2011-03-03 |
Curevac Gmbh |
Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
|
|
WO2011069528A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Lyophilization of nucleic acids in lactate-containing solutions
|
|
WO2011069529A1
(en)
|
2009-12-09 |
2011-06-16 |
Curevac Gmbh |
Mannose-containing solution for lyophilization, transfection and/or injection of nucleic acids
|
|
EP2387999A1
(en)
|
2010-05-21 |
2011-11-23 |
CureVac GmbH |
Histidine-containing solution for transfection and/or injection of nucleic acids and uses thereof
|
|
US20130121998A1
(en)
|
2010-06-16 |
2013-05-16 |
Myra A. Lipes |
Diagnosis of Myocardial Autoimmunity in Heart Disease
|
|
EP2449113B8
(en)
|
2010-07-30 |
2015-11-25 |
CureVac AG |
Complexation of nucleic acids with disulfide-crosslinked cationic components for transfection and immunostimulation
|
|
WO2012019630A1
(en)
|
2010-08-13 |
2012-02-16 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded protein
|
|
US20120058154A1
(en)
|
2010-08-20 |
2012-03-08 |
Selecta Biosciences, Inc. |
Synthetic nanocarrier vaccines comprising peptides obtained or derived from human influenza a virus m2e
|
|
WO2012037078A2
(en)
*
|
2010-09-14 |
2012-03-22 |
Stc.Unm |
Immunogenic respiratory syncytial virus glycoprotein-containing vlps and related compositions, constructs, and therapeutic methods
|
|
WO2012089225A1
(en)
|
2010-12-29 |
2012-07-05 |
Curevac Gmbh |
Combination of vaccination and inhibition of mhc class i restricted antigen presentation
|
|
WO2012116715A1
(en)
*
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in newborns and infants
|
|
WO2012113413A1
(en)
|
2011-02-21 |
2012-08-30 |
Curevac Gmbh |
Vaccine composition comprising complexed immunostimulatory nucleic acids and antigens packaged with disulfide-linked polyethyleneglycol/peptide conjugates
|
|
WO2012116714A1
(en)
|
2011-03-02 |
2012-09-07 |
Curevac Gmbh |
Vaccination in elderly patients
|
|
WO2013016126A1
(en)
|
2011-07-22 |
2013-01-31 |
The General Hospital Corporation |
Therapeutic nanoparticles and methods of use thereof
|
|
WO2013113326A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
|
|
EP2623121A1
(en)
|
2012-01-31 |
2013-08-07 |
Bayer Innovation GmbH |
Pharmaceutical composition comprising a polymeric carrier cargo complex and an antigen
|
|
WO2013113325A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Negatively charged nucleic acid comprising complexes for immunostimulation
|
|
WO2013120500A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded tumour antigen
|
|
WO2013120499A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly (a) sequence or a polyadenylation signal for increasing the expression of an encoded pathogenic antigen
|
|
WO2013120498A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded allergenic antigen or an autoimmune self-antigen
|
|
WO2013120497A1
(en)
|
2012-02-15 |
2013-08-22 |
Curevac Gmbh |
Nucleic acid comprising or coding for a histone stem-loop and a poly(a) sequence or a polyadenylation signal for increasing the expression of an encoded therapeutic protein
|
|
ES2660459T3
(es)
|
2012-03-27 |
2018-03-22 |
Curevac Ag |
Moléculas de ácido nucleico artificiales
|
|
CN104321432B
(zh)
|
2012-03-27 |
2018-08-10 |
库瑞瓦格股份公司 |
包含5′top utr的人工核酸分子
|
|
AU2013242404B2
(en)
|
2012-03-27 |
2018-08-30 |
CureVac SE |
Artificial nucleic acid molecules for improved protein or peptide expression
|
|
US20150306249A1
(en)
|
2012-05-25 |
2015-10-29 |
Curevac Gmbh |
Reversible immobilization and/or controlled release of nucleic acid containing nanoparticles by (biodegradable) polymer coatings
|
|
CN109045289A
(zh)
|
2013-02-22 |
2018-12-21 |
库瑞瓦格股份公司 |
疫苗接种和抑制pd-1途径的组合
|
|
RU2016109938A
(ru)
|
2013-08-21 |
2017-09-26 |
Куревак Аг |
Композиция и вакцина для лечения рака предстательной железы
|
|
CA2915712A1
(en)
|
2013-08-21 |
2015-02-26 |
Margit SCHNEE |
Rabies vaccine
|
|
WO2015024667A1
(en)
|
2013-08-21 |
2015-02-26 |
Curevac Gmbh |
Method for increasing expression of rna-encoded proteins
|
|
SG11201510748PA
(en)
|
2013-08-21 |
2016-03-30 |
Curevac Ag |
Composition and vaccine for treating lung cancer
|
|
CA2915730A1
(en)
|
2013-08-21 |
2015-02-26 |
Karl-Josef Kallen |
A combination rsv/influenza a vaccine
|
|
JP6896421B2
(ja)
*
|
2013-08-21 |
2021-06-30 |
キュアバック アーゲー |
呼吸器合胞体ウイルス（ｒｓｖ）ワクチン
|
|
ES2806575T3
(es)
|
2013-11-01 |
2021-02-18 |
Curevac Ag |
ARN modificado con propiedades inmunoestimuladoras disminuidas
|
|
US11254951B2
(en)
|
2014-12-30 |
2022-02-22 |
Curevac Ag |
Artificial nucleic acid molecules
|
|
WO2015101415A1
(en)
|
2013-12-30 |
2015-07-09 |
Curevac Gmbh |
Artificial nucleic acid molecules
|
|
AU2014375404C1
(en)
|
2013-12-30 |
2020-11-19 |
CureVac Manufacturing GmbH |
Methods for RNA analysis
|
|
SG11201603144QA
(en)
|
2013-12-30 |
2016-07-28 |
Curevac Ag |
Artificial nucleic acid molecules
|
|
CA2935878C
(en)
|
2014-03-12 |
2023-05-02 |
Curevac Ag |
Combination of vaccination and ox40 agonists
|
|
CA2936286A1
(en)
|
2014-04-01 |
2015-10-08 |
Curevac Ag |
Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant
|
|
MX2016016170A
(es)
|
2014-06-10 |
2017-03-28 |
Curevac Ag |
Metodos y medios para aumentar la produccion de arn.
|
|
DE202015010000U1
(de)
|
2014-12-12 |
2023-07-03 |
CureVac SE |
Artifizielle Nukleinsäuremoleküle für eine verbesserte Proteinexpression
|
|
EP3233113A1
(en)
|
2014-12-16 |
2017-10-25 |
CureVac AG |
Ebolavirus and marburgvirus vaccines
|
|
AU2015373404B2
(en)
|
2014-12-30 |
2021-09-09 |
CureVac SE |
Artificial nucleic acid molecules
|
|
WO2016165825A1
(en)
|
2015-04-13 |
2016-10-20 |
Curevac Ag |
Method for producing rna compositions
|
|
WO2016165831A1
(en)
|
2015-04-17 |
2016-10-20 |
Curevac Ag |
Lyophilization of rna
|
|
JP6912384B2
(ja)
|
2015-04-22 |
2021-08-04 |
キュアバック アーゲー |
癌疾患の処置のための、ｒｎａ含有組成物
|
|
SG11201708867UA
(en)
|
2015-04-30 |
2017-11-29 |
Curevac Ag |
Immobilized poly(n)polymerase
|
|
SG11201708681SA
(en)
|
2015-04-30 |
2017-11-29 |
Curevac Ag |
Method for in vitro transcription using an immobilized restriction enzyme
|
|
EP3294885B1
(en)
|
2015-05-08 |
2020-07-01 |
CureVac Real Estate GmbH |
Method for producing rna
|
|
US11559570B2
(en)
|
2015-05-15 |
2023-01-24 |
CureVac SE |
Prime-boost regimens involving administration of at least one mRNA construct
|
|
EP3297682B1
(en)
|
2015-05-20 |
2021-07-14 |
CureVac AG |
Dry powder composition comprising long-chain rna
|
|
WO2016184575A1
(en)
|
2015-05-20 |
2016-11-24 |
Curevac Ag |
Dry powder composition comprising long-chain rna
|
|
EP3744843A1
(en)
|
2015-05-29 |
2020-12-02 |
CureVac Real Estate GmbH |
A method for producing and purifying rna, comprising at least one step of tangential flow filtration
|
|
EP4098743A1
(en)
|
2015-05-29 |
2022-12-07 |
CureVac AG |
Method for adding cap structures to rna using immobilized enzymes
|
|
WO2016203025A1
(en)
|
2015-06-17 |
2016-12-22 |
Curevac Ag |
Vaccine composition
|
|
EP4239080A3
(en)
|
2015-07-01 |
2023-11-01 |
CureVac Manufacturing GmbH |
Method for analysis of an rna molecule
|
|
US10501768B2
(en)
|
2015-07-13 |
2019-12-10 |
Curevac Ag |
Method of producing RNA from circular DNA and corresponding template DNA
|
|
US20200085852A1
(en)
|
2015-08-05 |
2020-03-19 |
Curevac Ag |
Epidermal mrna vaccine
|
|
EP3332019B1
(en)
|
2015-08-07 |
2019-12-18 |
CureVac AG |
Process for the in vivo production of rna in a host cell
|
|
CN108138187B
(zh)
|
2015-08-10 |
2022-07-19 |
库瑞瓦格房地产有限公司 |
增加环状dna分子复制的方法
|
|
CN108026537B
(zh)
|
2015-08-28 |
2022-02-08 |
库瑞瓦格股份公司 |
人工核酸分子
|
|
EP3362576A1
(en)
|
2015-10-12 |
2018-08-22 |
CureVac AG |
Automated method for isolation, selection and/or detection of microorganisms or cells comprised in a solution
|
|
WO2017081110A1
(en)
|
2015-11-09 |
2017-05-18 |
Curevac Ag |
Rotavirus vaccines
|
|
US20180312545A1
(en)
|
2015-11-09 |
2018-11-01 |
Curevac Ag |
Optimized nucleic acid molecules
|
|
WO2017108087A1
(en)
|
2015-12-21 |
2017-06-29 |
Curevac Ag |
Inlay for a culture plate and corresponding method for preparing a culture plate system with such inlay
|
|
EP3701963A1
(en)
|
2015-12-22 |
2020-09-02 |
CureVac AG |
Method for producing rna molecule compositions
|
|
WO2017109161A1
(en)
|
2015-12-23 |
2017-06-29 |
Curevac Ag |
Method of rna in vitro transcription using a buffer containing a dicarboxylic acid or tricarboxylic acid or a salt thereof
|
|
EP3414340B1
(en)
|
2016-02-12 |
2023-08-09 |
CureVac SE |
Method for analyzing rna
|
|
EP3417069A1
(en)
|
2016-02-15 |
2018-12-26 |
CureVac AG |
Method for analyzing by-products of rna in vitro transcription
|
|
SG11201806340YA
(en)
|
2016-02-17 |
2018-09-27 |
Curevac Ag |
Zika virus vaccine
|
|
US11920174B2
(en)
|
2016-03-03 |
2024-03-05 |
CureVac SE |
RNA analysis by total hydrolysis and quantification of released nucleosides
|
|
WO2017162297A1
(en)
|
2016-03-24 |
2017-09-28 |
Curevac Ag |
Immobilized inorganic pyrophosphatase (ppase)
|
|
EP3445392A1
(en)
|
2016-04-22 |
2019-02-27 |
CureVac AG |
Rna encoding a tumor antigen
|
|
EP3448427A1
(en)
|
2016-04-29 |
2019-03-06 |
CureVac AG |
Rna encoding an antibody
|
|
US20180126003A1
(en)
|
2016-05-04 |
2018-05-10 |
Curevac Ag |
New targets for rna therapeutics
|
|
WO2017191264A1
(en)
|
2016-05-04 |
2017-11-09 |
Curevac Ag |
Nucleic acid molecules and uses thereof
|
|
EP3452101A2
(en)
|
2016-05-04 |
2019-03-13 |
CureVac AG |
Rna encoding a therapeutic protein
|
|
EP3452086A1
(en)
|
2016-05-04 |
2019-03-13 |
CureVac AG |
Influenza mrna vaccines
|
|
EP3464619A1
(en)
|
2016-05-25 |
2019-04-10 |
CureVac AG |
Novel biomarkers
|
|
US20190381180A1
(en)
|
2016-06-09 |
2019-12-19 |
Curevac Ag |
Hybrid carriers for nucleic acid cargo
|
|
US20190336611A1
(en)
|
2016-06-09 |
2019-11-07 |
Curevac Ag |
Hybrid carriers for nucleic acid cargo
|
|
WO2017212009A1
(en)
|
2016-06-09 |
2017-12-14 |
Curevac Ag |
Hybrid carriers for nucleic acid cargo
|
|
EP3468609A1
(en)
|
2016-06-09 |
2019-04-17 |
CureVac AG |
Cationic carriers for nucleic acid delivery
|
|
SG10201913631TA
(en)
|
2016-08-19 |
2020-03-30 |
Curevac Ag |
Rna for cancer therapy
|
|
BR112019008481A2
(pt)
|
2016-10-26 |
2020-03-03 |
Curevac Ag |
Vacinas de mrna de nanopartículas lipídicas
|
|
US11279923B2
(en)
|
2016-11-28 |
2022-03-22 |
Curevac Ag |
Method for purifying RNA
|
|
CN110582304A
(zh)
|
2016-12-08 |
2019-12-17 |
库尔维科公司 |
用于治疗或预防肝脏疾病的rna
|
|
WO2018104540A1
(en)
|
2016-12-08 |
2018-06-14 |
Curevac Ag |
Rnas for wound healing
|
|
WO2018115527A2
(en)
|
2016-12-23 |
2018-06-28 |
Curevac Ag |
Mers coronavirus vaccine
|
|
WO2018115507A2
(en)
|
2016-12-23 |
2018-06-28 |
Curevac Ag |
Henipavirus vaccine
|
|
WO2018115525A1
(en)
|
2016-12-23 |
2018-06-28 |
Curevac Ag |
Lassa virus vaccine
|
|
EP3595715A1
(en)
|
2017-03-17 |
2020-01-22 |
CureVac AG |
Rna vaccine and immune checkpoint inhibitors for combined anticancer therapy
|
|
JP2020513824A
(ja)
|
2017-03-24 |
2020-05-21 |
キュアバック アーゲー |
Ｃｒｉｓｐｒ関連タンパク質をコードする核酸、及びその使用
|
|
BR112019028280A2
(pt)
|
2017-07-04 |
2020-07-14 |
Curevac Ag |
moléculas de ácido nucleico
|
|
EP3673069A1
(en)
|
2017-08-22 |
2020-07-01 |
CureVac AG |
Bunyavirales vaccine
|
|
US11692002B2
(en)
|
2017-11-08 |
2023-07-04 |
CureVac SE |
RNA sequence adaptation
|
|
US11931406B2
(en)
|
2017-12-13 |
2024-03-19 |
CureVac SE |
Flavivirus vaccine
|
|
SG11202005760PA
(en)
|
2017-12-21 |
2020-07-29 |
Curevac Ag |
Linear double stranded dna coupled to a single support or a tag and methods for producing said linear double stranded dna
|
|
EP3773702A2
(en)
|
2018-04-05 |
2021-02-17 |
CureVac AG |
Novel yellow fever nucleic acid molecules for vaccination
|
|
SG11202008225PA
(en)
|
2018-04-17 |
2020-11-27 |
Curevac Ag |
Novel rsv rna molecules and compositions for vaccination
|
|
WO2020002525A1
(en)
|
2018-06-27 |
2020-01-02 |
Curevac Ag |
Novel lassa virus rna molecules and compositions for vaccination
|
|
MX2020013148A
(es)
|
2018-06-28 |
2021-03-02 |
CureVac RNA Printer GmbH |
Biorreactor para la transcripcion in vitro de arn.
|
|
SG11202106666UA
(en)
|
2018-12-21 |
2021-07-29 |
Curevac Ag |
Methods for rna analysis
|
|
CN113453707A
(zh)
|
2018-12-21 |
2021-09-28 |
库瑞瓦格股份公司 |
用于疟疾疫苗的rna
|
|
US11241493B2
(en)
|
2020-02-04 |
2022-02-08 |
Curevac Ag |
Coronavirus vaccine
|
|
US11576966B2
(en)
|
2020-02-04 |
2023-02-14 |
CureVac SE |
Coronavirus vaccine
|