RU2015145135A - Лечение воспалительных расстройств - Google Patents
Лечение воспалительных расстройств Download PDFInfo
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- RU2015145135A RU2015145135A RU2015145135A RU2015145135A RU2015145135A RU 2015145135 A RU2015145135 A RU 2015145135A RU 2015145135 A RU2015145135 A RU 2015145135A RU 2015145135 A RU2015145135 A RU 2015145135A RU 2015145135 A RU2015145135 A RU 2015145135A
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- RU
- Russia
- Prior art keywords
- compound
- alkyl
- disease
- use according
- nalidixic acid
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/473—Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
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- A—HUMAN NECESSITIES
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
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- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Otolaryngology (AREA)
- Dermatology (AREA)
- Communicable Diseases (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Obesity (AREA)
- Transplantation (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1306413.4 | 2013-04-09 | ||
| GB201306411A GB201306411D0 (en) | 2013-04-09 | 2013-04-09 | Treatment of inflammatory conditions |
| GB201306413A GB201306413D0 (en) | 2013-04-09 | 2013-04-09 | The local treatment of ophthalmic diseases |
| GB1306411.8 | 2013-04-09 | ||
| PCT/GB2014/051109 WO2014167327A1 (en) | 2013-04-09 | 2014-04-09 | The treatment of inflammatory disorders |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2015145135A true RU2015145135A (ru) | 2017-05-12 |
| RU2015145135A3 RU2015145135A3 (enExample) | 2018-02-14 |
Family
ID=50489339
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015145135A RU2015145135A (ru) | 2013-04-09 | 2014-04-09 | Лечение воспалительных расстройств |
| RU2015145134A RU2015145134A (ru) | 2013-04-09 | 2014-04-09 | Местное лечение воспалительных офтальмологических заболеваний |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2015145134A RU2015145134A (ru) | 2013-04-09 | 2014-04-09 | Местное лечение воспалительных офтальмологических заболеваний |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20160051526A1 (enExample) |
| EP (2) | EP2983713A1 (enExample) |
| JP (2) | JP2016516762A (enExample) |
| CN (2) | CN105431172A (enExample) |
| AU (2) | AU2014252807A1 (enExample) |
| CA (2) | CA2909111A1 (enExample) |
| GB (2) | GB2516137B (enExample) |
| HK (2) | HK1221166A1 (enExample) |
| RU (2) | RU2015145135A (enExample) |
| WO (2) | WO2014167326A1 (enExample) |
| ZA (2) | ZA201507724B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104496986A (zh) * | 2014-12-12 | 2015-04-08 | 苏州亚科化学试剂股份有限公司 | 萘啶酸的制备方法 |
| EP3369422A4 (en) * | 2015-10-29 | 2018-12-05 | Teika Pharmaceutical Co., Ltd. | External preparation |
| WO2018064354A1 (en) * | 2016-09-28 | 2018-04-05 | Medicon Pharmaceuticals, Inc. | Compositions and methods for treating ophthalmic conditions |
| WO2020021035A1 (en) * | 2018-07-26 | 2020-01-30 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of antibiotics for the treatment of immunoglobulin a nephropathy |
| US20230058189A1 (en) * | 2019-02-08 | 2023-02-23 | Frequency Therapeutics, Inc. | Quinolin-4-one and 4(1h)-cinnolinone compounds and methods of using same |
| FI4027983T3 (fi) * | 2019-09-11 | 2026-02-03 | Adverum Biotechnologies Inc | Silmän neovaskulaaristen sairauksien hoito afliberseptiä koodaavilla aav2-varianteilla |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19633480A1 (de) * | 1996-08-20 | 1998-02-26 | Bayer Ag | Oral applizierbare Formulierungen von Chinolon- und Naphthyridoncarbonsäuren |
| ID23053A (id) * | 1997-06-04 | 2000-01-20 | Lilly Co Eli | Karboksamida yang digunakan sebagai agonis 5-ht <if> |
| DE19729879C2 (de) * | 1997-07-11 | 1999-07-08 | Mann Gerhard Chem Pharm Fab | Lagerstabile ophthalmische Zusammensetzungen, umfassend Diclofenac und Ofloxacin |
| DE19826050A1 (de) * | 1998-06-12 | 1999-12-16 | Bayer Ag | Verfahren zur Herstellung von Chinolon- und Naphthyridoncarbonsäuren und deren Ester |
| CN1090959C (zh) * | 1999-06-17 | 2002-09-18 | 卢世全 | 一种治疗咳喘病的中、西复方成药及制备方法 |
| US6552020B1 (en) * | 1999-07-30 | 2003-04-22 | Allergan, Inc. | Compositions including antibiotics and methods for using same |
| JP2001342188A (ja) * | 2000-03-27 | 2001-12-11 | Takeda Chem Ind Ltd | 縮合ピラゾール誘導体、その製造法および用途 |
| JP3648132B2 (ja) * | 2000-06-19 | 2005-05-18 | 大正薬品工業株式会社 | キノロン系抗菌薬液体製剤及びその包装体 |
| EP1406700A1 (en) * | 2001-07-06 | 2004-04-14 | Sucampo AG | Composition for topical administration comprising an interleukin-2 inhibitor and an antimicrobial agent |
| AUPS017702A0 (en) * | 2002-01-25 | 2002-02-14 | Atopic Pty Ltd | Methods and compositions for the treatment of asthma and related disorders |
| KR101462825B1 (ko) * | 2004-05-03 | 2014-11-21 | 헤르메스 바이오사이언스, 인코포레이티드 | 약물 전달에 유용한 리포좀 |
| CA2881078C (en) * | 2004-06-24 | 2018-10-02 | Vertex Pharmaceuticals Incorporated | Modulators of atp-binding cassette transporters |
| JP2006028031A (ja) * | 2004-07-12 | 2006-02-02 | Ltt Bio-Pharma Co Ltd | 経粘膜吸収用薬物封入ナノ粒子 |
| MX2007003968A (es) * | 2004-10-01 | 2008-03-04 | Ramscor Inc | Composiciones de farmaco de liberacion sostenida convenientemente implantables. |
| EP1954800A4 (en) * | 2005-12-02 | 2010-03-03 | Health Enhancement Products In | COMPOSITION AND USE OF PHYTO-PERCOLATE FOR THE TREATMENT OF DISEASE |
| US20080138350A1 (en) * | 2006-10-20 | 2008-06-12 | Bennett Michael D | Process for use of fluoroquinolones to reduce or modulate inflammation due to eye disease or ophthalmic surgery |
| CN101129386A (zh) * | 2007-07-17 | 2008-02-27 | 长治市三宝生化药业有限公司 | 一种含环丙沙星和地塞米松的局部悬浮滴眼剂 |
| CN101801414B (zh) * | 2007-09-21 | 2013-04-03 | 株式会社日本高度医疗研究会 | 口腔用和皮肤用组合物 |
| GB0719518D0 (en) * | 2007-10-05 | 2007-11-14 | Therapeutics Ltd E | Therapy |
| CA2711957C (en) * | 2007-10-11 | 2019-03-19 | The Regents Of The University Of California | Use of inhibitors of n-acylethanolamine-hydrolyzing acid amidase as anti-inflamatory medicaments |
| MX342183B (es) * | 2008-09-09 | 2016-09-20 | Allergan Inc | Suspension oftalmica para uso ocular. |
| CN102325532B (zh) * | 2008-10-07 | 2015-06-17 | Mpex医药有限公司 | 用于减轻肺部炎症的左氧氟沙星吸入剂 |
| CN102711760A (zh) * | 2009-08-19 | 2012-10-03 | Mpex医药有限公司 | 雾化抗生素用于治疗慢性阻塞性肺病的用途 |
| US20130079353A1 (en) * | 2009-12-22 | 2013-03-28 | Karsten Gülow | Fluoroquinolones for the treatment and/or prophylaxis of inflammatory diseases |
| EP2694048B1 (en) * | 2011-04-05 | 2020-10-07 | Optosolve Research & Development Ltd | Ophthalmic treatments |
-
2014
- 2014-04-09 US US14/783,038 patent/US20160051526A1/en not_active Abandoned
- 2014-04-09 JP JP2016507059A patent/JP2016516762A/ja active Pending
- 2014-04-09 EP EP14717821.4A patent/EP2983713A1/en not_active Withdrawn
- 2014-04-09 HK HK16109377.6A patent/HK1221166A1/zh unknown
- 2014-04-09 AU AU2014252807A patent/AU2014252807A1/en not_active Abandoned
- 2014-04-09 RU RU2015145135A patent/RU2015145135A/ru not_active Application Discontinuation
- 2014-04-09 WO PCT/GB2014/051108 patent/WO2014167326A1/en not_active Ceased
- 2014-04-09 CA CA2909111A patent/CA2909111A1/en not_active Abandoned
- 2014-04-09 GB GB1406390.3A patent/GB2516137B/en active Active
- 2014-04-09 JP JP2016507058A patent/JP2016516761A/ja active Pending
- 2014-04-09 GB GB1406396.0A patent/GB2516138C/en active Active
- 2014-04-09 CA CA2909117A patent/CA2909117A1/en not_active Abandoned
- 2014-04-09 HK HK16109376.7A patent/HK1221190A1/zh unknown
- 2014-04-09 CN CN201480030407.7A patent/CN105431172A/zh active Pending
- 2014-04-09 US US14/782,975 patent/US20160068527A1/en not_active Abandoned
- 2014-04-09 RU RU2015145134A patent/RU2015145134A/ru not_active Application Discontinuation
- 2014-04-09 EP EP14717820.6A patent/EP2983788A1/en not_active Withdrawn
- 2014-04-09 AU AU2014252808A patent/AU2014252808A1/en not_active Abandoned
- 2014-04-09 CN CN201480030418.5A patent/CN105555364A/zh active Pending
- 2014-04-09 WO PCT/GB2014/051109 patent/WO2014167327A1/en not_active Ceased
-
2015
- 2015-10-15 ZA ZA2015/07724A patent/ZA201507724B/en unknown
- 2015-10-15 ZA ZA201507718A patent/ZA201507718B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1221166A1 (zh) | 2017-05-26 |
| AU2014252808A1 (en) | 2015-11-12 |
| CA2909117A1 (en) | 2014-10-16 |
| GB2516138A (en) | 2015-01-14 |
| CA2909111A1 (en) | 2014-10-16 |
| US20160068527A1 (en) | 2016-03-10 |
| RU2015145134A (ru) | 2017-05-16 |
| EP2983788A1 (en) | 2016-02-17 |
| WO2014167327A1 (en) | 2014-10-16 |
| EP2983713A1 (en) | 2016-02-17 |
| ZA201507718B (en) | 2019-11-27 |
| US20160051526A1 (en) | 2016-02-25 |
| RU2015145134A3 (enExample) | 2018-03-16 |
| WO2014167326A1 (en) | 2014-10-16 |
| CN105555364A (zh) | 2016-05-04 |
| GB2516137A (en) | 2015-01-14 |
| JP2016516761A (ja) | 2016-06-09 |
| GB201406390D0 (en) | 2014-05-21 |
| GB2516137B (en) | 2016-02-17 |
| CN105431172A (zh) | 2016-03-23 |
| JP2016516762A (ja) | 2016-06-09 |
| ZA201507724B (en) | 2019-02-27 |
| GB2516138C (en) | 2015-12-09 |
| GB2516138B (en) | 2015-11-25 |
| HK1221190A1 (zh) | 2017-05-26 |
| AU2014252807A1 (en) | 2015-11-12 |
| GB201406396D0 (en) | 2014-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20190520 |