RU2013125754A - Усовершенствованный алгоритм для обнаружения диабета - Google Patents
Усовершенствованный алгоритм для обнаружения диабета Download PDFInfo
- Publication number
- RU2013125754A RU2013125754A RU2013125754/14A RU2013125754A RU2013125754A RU 2013125754 A RU2013125754 A RU 2013125754A RU 2013125754/14 A RU2013125754/14 A RU 2013125754/14A RU 2013125754 A RU2013125754 A RU 2013125754A RU 2013125754 A RU2013125754 A RU 2013125754A
- Authority
- RU
- Russia
- Prior art keywords
- radiation
- intensity
- disease
- fluorescent radiation
- target tissue
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/18—Arrangement of plural eye-testing or -examining apparatus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/117—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes
- A61B3/1173—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for examining the anterior chamber or the anterior chamber angle, e.g. gonioscopes for examining the eye lens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0068—Confocal scanning
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0071—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
- A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
- A61B5/1477—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means non-invasive
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/48—Other medical applications
- A61B5/4842—Monitoring progression or stage of a disease
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6486—Measuring fluorescence of biological material, e.g. DNA, RNA, cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/65—Raman scattering
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Pathology (AREA)
- Optics & Photonics (AREA)
- Ophthalmology & Optometry (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Abstract
1. Способ определения наличия заболевания, которым страдает пациент, содержащий этапы, на которых:облучают целевую ткань пациента возбуждающим излучением;обнаруживают флуоресцентное излучение, генерируемое целевой тканью в ответ на возбуждающее излучение;сравнивают характеристику обнаруженного флуоресцентного излучения с ожидаемой характеристикой флуоресцентного излучения; иопределяют наличие заболевания, которым страдает пациент, на основе результатов этапа сравнения.2. Способ по п.1, в котором этап сравнения содержит сравнение характеристики обнаруженного флуоресцентного излучения с ожидаемой характеристикой флуоресцентного излучения для индивидов примерно одинакового с пациентом возраста и веса.3. Способ по п.2, в котором этап сравнения содержит сравнение характеристики обнаруженного флуоресцентного излучения с ожидаемой характеристикой флуоресцентного излучения для индивидов, у которых заболевание отсутствует.4. Способ по п.1, в котором этап обнаружения содержит обнаружение интенсивности флуоресцентного излучения, генерируемого целевой тканью.5. Способ по п.4, дополнительно содержащий этапы, на которых:обнаруживают интенсивность излучения, обратно-рассеянного от целевой ткани; иосуществляют нормализацию обнаруженной интенсивности флуоресцентного излучения с учетом интенсивности обратно-рассеянного излучения.6. Способ по п.5, в котором этап сравнения содержит сравнение нормализованной обнаруженной интенсивности флуоресцентного излучения с ожидаемой нормализованной интенсивностью флуоресцентного излучения для индивидов, у которых заболевание отсутствует.7. Способ по п.1, в котором эта
Claims (9)
1. Способ определения наличия заболевания, которым страдает пациент, содержащий этапы, на которых:
облучают целевую ткань пациента возбуждающим излучением;
обнаруживают флуоресцентное излучение, генерируемое целевой тканью в ответ на возбуждающее излучение;
сравнивают характеристику обнаруженного флуоресцентного излучения с ожидаемой характеристикой флуоресцентного излучения; и
определяют наличие заболевания, которым страдает пациент, на основе результатов этапа сравнения.
2. Способ по п.1, в котором этап сравнения содержит сравнение характеристики обнаруженного флуоресцентного излучения с ожидаемой характеристикой флуоресцентного излучения для индивидов примерно одинакового с пациентом возраста и веса.
3. Способ по п.2, в котором этап сравнения содержит сравнение характеристики обнаруженного флуоресцентного излучения с ожидаемой характеристикой флуоресцентного излучения для индивидов, у которых заболевание отсутствует.
4. Способ по п.1, в котором этап обнаружения содержит обнаружение интенсивности флуоресцентного излучения, генерируемого целевой тканью.
5. Способ по п.4, дополнительно содержащий этапы, на которых:
обнаруживают интенсивность излучения, обратно-рассеянного от целевой ткани; и
осуществляют нормализацию обнаруженной интенсивности флуоресцентного излучения с учетом интенсивности обратно-рассеянного излучения.
6. Способ по п.5, в котором этап сравнения содержит сравнение нормализованной обнаруженной интенсивности флуоресцентного излучения с ожидаемой нормализованной интенсивностью флуоресцентного излучения для индивидов, у которых заболевание отсутствует.
7. Способ по п.1, в котором этап обнаружения содержит обнаружение характеристики флуоресцентного излучения, генерируемого целевой тканью, с использованием, по меньшей мере, одной из технологии на основе интенсивности, технологии на основе фазового сдвига или технологии на основе полярной анизотропии.
8. Способ по п.1, в котором сравниваемая характеристика является элементом, выбранным из группы, состоящей из возраста, пола, роста, веса, индекса массы тела (BMI), окружности талии, HbA1c, биомаркеров, этнической принадлежности, приверженности к курению, наличия высокого кровяного давления, наличия высокого содержания холестерина, сухости глаз, истории заболевания диабетом в семье, наличия катаракты или других заболеваний.
9. Способ по п.1, в котором заболевание представляет собой элемент, выбранный из группы, состоящей из диабета, заболевания глаз, вызванного диабетом, ретинопатии, ретинальной васкулярной окклюзии, витреоретинопатии, возрастной дегенериции макулы, наследственной ретинальной дегенерации, псевдоопухолевого состояния церебральных сосудов, глаукомы, катаракты.
Applications Claiming Priority (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41082710P | 2010-11-05 | 2010-11-05 | |
US41083510P | 2010-11-05 | 2010-11-05 | |
US41082510P | 2010-11-05 | 2010-11-05 | |
US41083410P | 2010-11-05 | 2010-11-05 | |
US41083910P | 2010-11-05 | 2010-11-05 | |
US41083110P | 2010-11-05 | 2010-11-05 | |
US41083310P | 2010-11-05 | 2010-11-05 | |
US41083010P | 2010-11-05 | 2010-11-05 | |
US61/410,825 | 2010-11-05 | ||
US61/410,835 | 2010-11-05 | ||
US61/410,830 | 2010-11-05 | ||
US61/410,831 | 2010-11-05 | ||
US61/410,839 | 2010-11-05 | ||
US61/410,827 | 2010-11-05 | ||
US61/410,833 | 2010-11-05 | ||
US61/410,834 | 2010-11-05 | ||
PCT/US2011/059654 WO2012061836A2 (en) | 2010-11-05 | 2011-11-07 | Improved algorithm for detection of diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
RU2013125754A true RU2013125754A (ru) | 2014-12-10 |
Family
ID=46025163
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU2013125754/14A RU2013125754A (ru) | 2010-11-05 | 2011-11-07 | Усовершенствованный алгоритм для обнаружения диабета |
Country Status (12)
Country | Link |
---|---|
US (2) | US8989848B2 (ru) |
EP (2) | EP2635186B1 (ru) |
JP (2) | JP6188225B2 (ru) |
KR (1) | KR101889575B1 (ru) |
CN (2) | CN103188993B (ru) |
AU (2) | AU2011323111B2 (ru) |
BR (2) | BR112013010015A2 (ru) |
CA (2) | CA2813270C (ru) |
IL (2) | IL225555A (ru) |
RU (1) | RU2013125754A (ru) |
TW (2) | TWI530272B (ru) |
WO (2) | WO2012061835A2 (ru) |
Families Citing this family (101)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2013125754A (ru) | 2010-11-05 | 2014-12-10 | Фридом Медитек, Инк. | Усовершенствованный алгоритм для обнаружения диабета |
JP2014521490A (ja) | 2011-08-15 | 2014-08-28 | エピック リサーチ アンド ダイアグノスティクス, インコーポレイテッド | 指先またはつま先の周囲の光度からの局所的生理学的ステータス |
US20130053699A1 (en) * | 2011-08-30 | 2013-02-28 | National Applied Research Laboratories Instrument Technology Research Center | Apparatus and method for performing photodynamic diagnosis and photodynamic therapy |
US11632520B2 (en) * | 2011-11-14 | 2023-04-18 | Aaron Chien | LED light has built-in camera-assembly to capture colorful digital-data under dark environment |
US9854970B2 (en) | 2012-02-21 | 2018-01-02 | Massachusetts Eye & Ear Infirmary | Calculating conjunctival redness |
WO2013162631A1 (en) | 2012-04-25 | 2013-10-31 | Compliance Software, Inc. | Capturing and processing instant drug test results using a mobile device |
USD701320S1 (en) | 2012-04-25 | 2014-03-18 | Compliance Software, Inc. | Adaptable housing for mobile device based drug testing |
US9094493B2 (en) | 2012-04-25 | 2015-07-28 | Compliance Software, Inc. | Capturing and processing instant drug test results using a mobile device |
US9423870B2 (en) * | 2012-05-08 | 2016-08-23 | Google Inc. | Input determination method |
JP6106883B2 (ja) * | 2012-08-27 | 2017-04-05 | 学校法人福岡大学 | 第二次高調波光を用いた新規コラーゲン線維化評価モデル |
US10222336B2 (en) * | 2012-10-31 | 2019-03-05 | Hewlett-Packard Development Company, L.P. | Multiple spectral measurement acquisition apparatus and the methods of using same |
RU2505812C1 (ru) * | 2013-02-27 | 2014-01-27 | Антонина Сергеевна Тишкова | Способ дооперационного определения плотности ядра хрусталика |
WO2014151114A1 (en) | 2013-03-15 | 2014-09-25 | Vasoptic Medical Inc. | Ophthalmic examination and disease management with multiple illumination modalities |
JP6181420B2 (ja) * | 2013-05-15 | 2017-08-16 | 株式会社トプコン | 眼底撮影装置 |
FI126928B (en) | 2013-06-20 | 2017-08-15 | Icare Finland Oy | OPTOMETRIC INSTRUMENT WITH MEASURES TO DIRECT THE INSTRUMENT AND PROCEDURE TO PERFORM THIS |
WO2015112630A1 (en) * | 2014-01-22 | 2015-07-30 | California Institute Of Technology | Intrinsic frequency based determination of insulin resistance |
JP6291875B2 (ja) * | 2014-01-31 | 2018-03-14 | セイコーエプソン株式会社 | 血糖値計測装置及び血糖値計測方法 |
US9551763B1 (en) | 2016-01-21 | 2017-01-24 | Lockheed Martin Corporation | Diamond nitrogen vacancy sensor with common RF and magnetic fields generator |
US9853837B2 (en) | 2014-04-07 | 2017-12-26 | Lockheed Martin Corporation | High bit-rate magnetic communication |
US9817081B2 (en) | 2016-01-21 | 2017-11-14 | Lockheed Martin Corporation | Magnetometer with light pipe |
US9910104B2 (en) | 2015-01-23 | 2018-03-06 | Lockheed Martin Corporation | DNV magnetic field detector |
US9590601B2 (en) | 2014-04-07 | 2017-03-07 | Lockheed Martin Corporation | Energy efficient controlled magnetic field generator circuit |
US9638821B2 (en) | 2014-03-20 | 2017-05-02 | Lockheed Martin Corporation | Mapping and monitoring of hydraulic fractures using vector magnetometers |
US9845153B2 (en) | 2015-01-28 | 2017-12-19 | Lockheed Martin Corporation | In-situ power charging |
US9557391B2 (en) | 2015-01-23 | 2017-01-31 | Lockheed Martin Corporation | Apparatus and method for high sensitivity magnetometry measurement and signal processing in a magnetic detection system |
US9910105B2 (en) | 2014-03-20 | 2018-03-06 | Lockheed Martin Corporation | DNV magnetic field detector |
US10088452B2 (en) | 2016-01-12 | 2018-10-02 | Lockheed Martin Corporation | Method for detecting defects in conductive materials based on differences in magnetic field characteristics measured along the conductive materials |
US10168393B2 (en) | 2014-09-25 | 2019-01-01 | Lockheed Martin Corporation | Micro-vacancy center device |
US9829545B2 (en) | 2015-11-20 | 2017-11-28 | Lockheed Martin Corporation | Apparatus and method for hypersensitivity detection of magnetic field |
US10520558B2 (en) | 2016-01-21 | 2019-12-31 | Lockheed Martin Corporation | Diamond nitrogen vacancy sensor with nitrogen-vacancy center diamond located between dual RF sources |
US10338162B2 (en) | 2016-01-21 | 2019-07-02 | Lockheed Martin Corporation | AC vector magnetic anomaly detection with diamond nitrogen vacancies |
EP3125760B1 (en) * | 2014-04-02 | 2020-12-30 | BiliBaby, LLC | System and method for determining bilirubin levels in newborn babies |
CN106535740B (zh) * | 2014-05-02 | 2019-10-15 | 马萨诸塞眼科耳科诊所 | 用于确定表示角膜染色量的分数的方法和系统 |
US9770213B2 (en) | 2014-10-30 | 2017-09-26 | Koninklijke Philips N.V. | Device, system and method for extracting physiological information |
US20160183789A1 (en) * | 2014-12-31 | 2016-06-30 | Higi Sh Llc | User initiated and feedback controlled system for detection of biomolecules through the eye |
WO2016190909A2 (en) | 2015-01-28 | 2016-12-01 | Lockheed Martin Corporation | Magnetic navigation methods and systems utilizing power grid and communication network |
GB2550809A (en) | 2015-02-04 | 2017-11-29 | Lockheed Corp | Apparatus and method for estimating absolute axes' orientations for a magnetic detection system |
WO2016126436A1 (en) | 2015-02-04 | 2016-08-11 | Lockheed Martin Corporation | Apparatus and method for recovery of three dimensional magnetic field from a magnetic detection system |
WO2016157156A1 (en) | 2015-04-02 | 2016-10-06 | Livspek Medical Technologies Inc. | Method and apparatus for a spectral detector for noninvasive detection and monitoring of a variety of biomarkers and other blood constituents in the conjunctiva |
WO2016172576A1 (en) | 2015-04-22 | 2016-10-27 | Board Of Trustees Of Northern Illinois University | Non-invasive occular biomarkers for early diagnosis of diseases |
FI127908B (en) * | 2015-09-22 | 2019-05-15 | Teknologian Tutkimuskeskus Vtt Oy | Method and apparatus for measuring surface height |
WO2017078766A1 (en) | 2015-11-04 | 2017-05-11 | Lockheed Martin Corporation | Magnetic band-pass filter |
WO2017087013A1 (en) | 2015-11-20 | 2017-05-26 | Lockheed Martin Corporation | Apparatus and method for closed loop processing for a magnetic detection system |
WO2017095454A1 (en) | 2015-12-01 | 2017-06-08 | Lockheed Martin Corporation | Communication via a magnio |
WO2017127081A1 (en) | 2016-01-21 | 2017-07-27 | Lockheed Martin Corporation | Diamond nitrogen vacancy sensor with circuitry on diamond |
WO2017127098A1 (en) | 2016-01-21 | 2017-07-27 | Lockheed Martin Corporation | Diamond nitrogen vacancy sensed ferro-fluid hydrophone |
AU2016387314A1 (en) | 2016-01-21 | 2018-09-06 | Lockheed Martin Corporation | Magnetometer with a light emitting diode |
WO2017127090A1 (en) | 2016-01-21 | 2017-07-27 | Lockheed Martin Corporation | Higher magnetic sensitivity through fluorescence manipulation by phonon spectrum control |
US10088468B2 (en) * | 2016-02-04 | 2018-10-02 | Nova Biomedical Corporation | Analyte system and method for determining hemoglobin parameters in whole blood |
US11209358B2 (en) | 2016-03-14 | 2021-12-28 | Analog Devices, Inc. | Blocking specular reflections |
WO2017160766A1 (en) * | 2016-03-14 | 2017-09-21 | Analog Devices, Inc. | Optical evaluation of skin type and condition |
US10779720B2 (en) * | 2016-03-26 | 2020-09-22 | Yuscan Usa, Llc | Device for noninvasive determination of pathophysiological conditions |
US10145910B2 (en) | 2017-03-24 | 2018-12-04 | Lockheed Martin Corporation | Photodetector circuit saturation mitigation for magneto-optical high intensity pulses |
US10345395B2 (en) | 2016-12-12 | 2019-07-09 | Lockheed Martin Corporation | Vector magnetometry localization of subsurface liquids |
US20170343621A1 (en) | 2016-05-31 | 2017-11-30 | Lockheed Martin Corporation | Magneto-optical defect center magnetometer |
US10408890B2 (en) | 2017-03-24 | 2019-09-10 | Lockheed Martin Corporation | Pulsed RF methods for optimization of CW measurements |
US10677953B2 (en) | 2016-05-31 | 2020-06-09 | Lockheed Martin Corporation | Magneto-optical detecting apparatus and methods |
US10527746B2 (en) | 2016-05-31 | 2020-01-07 | Lockheed Martin Corporation | Array of UAVS with magnetometers |
US10281550B2 (en) | 2016-11-14 | 2019-05-07 | Lockheed Martin Corporation | Spin relaxometry based molecular sequencing |
US10228429B2 (en) | 2017-03-24 | 2019-03-12 | Lockheed Martin Corporation | Apparatus and method for resonance magneto-optical defect center material pulsed mode referencing |
US10359479B2 (en) | 2017-02-20 | 2019-07-23 | Lockheed Martin Corporation | Efficient thermal drift compensation in DNV vector magnetometry |
US10330744B2 (en) | 2017-03-24 | 2019-06-25 | Lockheed Martin Corporation | Magnetometer with a waveguide |
US10371765B2 (en) | 2016-07-11 | 2019-08-06 | Lockheed Martin Corporation | Geolocation of magnetic sources using vector magnetometer sensors |
US10345396B2 (en) | 2016-05-31 | 2019-07-09 | Lockheed Martin Corporation | Selected volume continuous illumination magnetometer |
US10317279B2 (en) | 2016-05-31 | 2019-06-11 | Lockheed Martin Corporation | Optical filtration system for diamond material with nitrogen vacancy centers |
US10338163B2 (en) | 2016-07-11 | 2019-07-02 | Lockheed Martin Corporation | Multi-frequency excitation schemes for high sensitivity magnetometry measurement with drift error compensation |
US10274550B2 (en) | 2017-03-24 | 2019-04-30 | Lockheed Martin Corporation | High speed sequential cancellation for pulsed mode |
US10571530B2 (en) | 2016-05-31 | 2020-02-25 | Lockheed Martin Corporation | Buoy array of magnetometers |
US10400967B2 (en) * | 2016-06-13 | 2019-09-03 | Novartis Ag | Ophthalmic illumination system with controlled chromaticity |
JP6776672B2 (ja) * | 2016-07-08 | 2020-10-28 | 住友電気工業株式会社 | 品質評価方法及び品質評価装置 |
RU2647788C2 (ru) * | 2016-07-18 | 2018-03-19 | федеральное государственное бюджетное образовательное учреждение высшего образования "Красноярский государственный медицинский университет имени профессора В.Ф. Войно-Ясенецкого" Министерства Здравоохранения Российской Федерации (ФГБОУ ВО КРАСГМУ им. проф. В.Ф. Войно-Ясенецкого Минздрава России) | Способ определения времени ультразвукового воздействия при хирургии возрастных катаракт |
JP6392999B2 (ja) * | 2016-07-19 | 2018-09-19 | 株式会社アサヒビジョン | 眼球分析装置および眼球分析方法 |
WO2018016410A1 (ja) * | 2016-07-19 | 2018-01-25 | 株式会社アサヒビジョン | 眼球分析装置および眼球分析方法 |
US11369295B2 (en) * | 2016-07-20 | 2022-06-28 | University Of Maryland, Baltimore | Silicone hydrogel based fluorescent assay and contact lens |
JP7308144B2 (ja) * | 2016-10-13 | 2023-07-13 | トランスレイタム メディカス インコーポレイテッド | 眼疾患の検出のためのシステム及び方法 |
CN107239050A (zh) * | 2017-01-23 | 2017-10-10 | 谢圣超 | 一种基于互联网的眼科用手持式交联治疗控制系统 |
US10338164B2 (en) | 2017-03-24 | 2019-07-02 | Lockheed Martin Corporation | Vacancy center material with highly efficient RF excitation |
US10371760B2 (en) | 2017-03-24 | 2019-08-06 | Lockheed Martin Corporation | Standing-wave radio frequency exciter |
US10379174B2 (en) | 2017-03-24 | 2019-08-13 | Lockheed Martin Corporation | Bias magnet array for magnetometer |
US10459041B2 (en) | 2017-03-24 | 2019-10-29 | Lockheed Martin Corporation | Magnetic detection system with highly integrated diamond nitrogen vacancy sensor |
WO2018174917A1 (en) * | 2017-03-24 | 2018-09-27 | Lockheed Martin Corporation | Precision adjustability of optical components in a magnetometer sensor |
JP2018166650A (ja) * | 2017-03-29 | 2018-11-01 | 株式会社トプコン | 眼科装置 |
JP2018166649A (ja) * | 2017-03-29 | 2018-11-01 | 株式会社トプコン | 眼科装置 |
US11744489B2 (en) * | 2017-05-12 | 2023-09-05 | National University Of Singapore | Noninvasive optical sensor for analyzing a level of a substance in a subject by illuminating the sclera |
US10908289B2 (en) | 2017-11-19 | 2021-02-02 | Sensonica Limited | Navigation system, navigation method and receivers |
EP3486688A1 (en) | 2017-11-19 | 2019-05-22 | Sensonica Limited | Radiation detection apparatus and method |
US10852237B2 (en) | 2018-03-26 | 2020-12-01 | Centrillion Technologies Taiwan Co., Ltd. | Microarray, imaging system and method for microarray imaging |
WO2019189971A1 (ko) * | 2018-03-30 | 2019-10-03 | 주식회사 홍복 | 당뇨병 및 전조 증상을 진단하기 위해 홍채 영상 및 망막 영상을 인공지능으로 분석하는 방법 |
JP6410199B1 (ja) * | 2018-05-11 | 2018-10-24 | アクティブ販売株式会社 | 対象体選別装置 |
US10878781B2 (en) | 2018-08-09 | 2020-12-29 | Chun-Ding HUANG | Image processing method and head-mounted display system |
TWI693533B (zh) * | 2018-08-09 | 2020-05-11 | 黃鈞鼎 | 影像處理方法及頭戴式影像系統 |
JP7336756B2 (ja) * | 2018-09-28 | 2023-09-01 | 公立大学法人名古屋市立大学 | 光線治療装置および光線治療装置の光出射方法 |
CN109691977B (zh) * | 2018-12-29 | 2023-11-28 | 佛山科学技术学院 | 非共聚焦自适应光学成像系统 |
US11263981B2 (en) * | 2019-05-31 | 2022-03-01 | Sharp Kabushiki Kaisha | Display device and head-mounted display |
AU2020295824A1 (en) * | 2019-06-20 | 2022-01-20 | Spring Vision Ltd. | System and method for fluorescence imaging of biological tissues |
TWI740169B (zh) * | 2019-06-26 | 2021-09-21 | 達爾生技股份有限公司 | 量測裝置及量測方法 |
GB201913476D0 (en) * | 2019-09-18 | 2019-10-30 | Univ Birmingham | Traumatic brain injury detection |
WO2021067435A1 (en) * | 2019-10-01 | 2021-04-08 | Yuscan Usa, Llc | Devices and methods for determining a disease state based total lens fluorescence |
TWI758219B (zh) * | 2021-08-10 | 2022-03-11 | 國立臺灣科技大學 | 遠紅外線的生物效應的評估方法 |
WO2023028353A1 (en) * | 2021-08-27 | 2023-03-02 | Bilibaby, Inc. | Systems and methods for determining and communicating levels of bilirubin and other subcutaneous substances |
TWI798140B (zh) * | 2022-07-28 | 2023-04-01 | 國立台灣大學 | 一種非侵入式影像觀測人體皮膚中神經末梢密度的方法及裝置 |
Family Cites Families (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3432227A (en) | 1962-09-11 | 1969-03-11 | Joseph W Soper | Keratometer with adjustable fixation target attachment for determining corneal topography |
US4895159A (en) | 1982-09-10 | 1990-01-23 | Weiss Jeffrey N | Diabetes detection method |
US4883351A (en) | 1982-09-10 | 1989-11-28 | Weiss Jeffrey N | Apparatus for the detection of diabetes and other abnormalities affecting the lens of the eye |
DE3434319A1 (de) | 1984-09-19 | 1986-04-03 | Oculus-Optikgeräte GmbH, 6330 Wetzlar | Verfahren zur fixationskontrolle des patientenauges bei perimetermessungen |
JPS61288824A (ja) | 1985-06-18 | 1986-12-19 | 株式会社トプコン | 眼科器械用固視装置 |
US5035500A (en) | 1988-08-12 | 1991-07-30 | Rorabaugh Dale A | Automated ocular perimetry, particularly kinetic perimetry |
US5203328A (en) | 1991-07-17 | 1993-04-20 | Georgia Tech Research Corporation | Apparatus and methods for quantitatively measuring molecular changes in the ocular lens |
JPH06114006A (ja) * | 1992-10-02 | 1994-04-26 | Canon Inc | 検査装置 |
US5442412A (en) | 1994-04-25 | 1995-08-15 | Autonomous Technologies Corp. | Patient responsive eye fixation target method and system |
JP3592416B2 (ja) * | 1995-10-31 | 2004-11-24 | 晃敏 吉田 | 眼内物質の測定装置 |
JP3683059B2 (ja) * | 1995-12-13 | 2005-08-17 | 晃敏 吉田 | 眼球から発生する光による眼内物質の測定装置 |
DE69633377T2 (de) * | 1995-12-13 | 2005-09-22 | Yoshida, Akitoshi, Asahikawa | Vorrichtung zur Anzeige intraokularer Substanzen durch Messung des vom Auge reflektierten Lichtes |
US5947955A (en) | 1997-09-12 | 1999-09-07 | Lasersight Technologies, Inc. | Active eye movement and positioning control device |
US6004313A (en) | 1998-06-26 | 1999-12-21 | Visx, Inc. | Patient fixation system and method for laser eye surgery |
AUPP528498A0 (en) | 1998-08-14 | 1998-09-10 | Lions Eye Institute Of Western Australia Incorporated, The | Surgical visual feedback and eye fixation method and apparatus |
AU760402B2 (en) * | 1998-12-23 | 2003-05-15 | Medispectra, Inc. | Optical methods and systems for cervical screening |
US6088606A (en) * | 1999-03-22 | 2000-07-11 | Spectrx, Inc. | Method and apparatus for determining a duration of a medical condition |
US6869427B1 (en) | 2000-06-15 | 2005-03-22 | Kamran K. Shokoohi | LED fixation device for topical anesthesia eye surgery |
EP1913866A1 (en) * | 2000-08-21 | 2008-04-23 | The General Hospital Corporation | Methods for diagnosing a neurodegenerative condition |
US7139598B2 (en) | 2002-04-04 | 2006-11-21 | Veralight, Inc. | Determination of a measure of a glycation end-product or disease state using tissue fluorescence |
US7043288B2 (en) | 2002-04-04 | 2006-05-09 | Inlight Solutions, Inc. | Apparatus and method for spectroscopic analysis of tissue to detect diabetes in an individual |
US6704588B2 (en) * | 2001-06-16 | 2004-03-09 | Rafat R. Ansari | Method and apparatus for the non-invasive measurement of blood glucose levels in humans |
CN100998499B (zh) * | 2003-10-28 | 2013-07-24 | 薇拉莱特公司 | 使用组织荧光确定某一糖化终产物或疾病状态 |
WO2006009906A2 (en) * | 2004-06-17 | 2006-01-26 | The Regents Of The University Of California | Time-resolved non-invasive autofluorescence device for detecting diabetes |
WO2007076479A1 (en) * | 2005-12-22 | 2007-07-05 | Alcon Refractivehorizons, Inc. | Pupil reflection eye tracking system and method |
US8129105B2 (en) * | 2006-04-13 | 2012-03-06 | Ralph Zuckerman | Method and apparatus for the non-invasive measurement of tissue function and metabolism by determination of steady-state fluorescence anisotropy |
FR2906387A1 (fr) * | 2006-09-21 | 2008-03-28 | St Microelectronics Sa | Procede et dispositif de selection d'images dans une sequence d'images d'iris recue en flux continu |
AU2007317007B2 (en) * | 2006-11-10 | 2013-08-08 | Lars Michael Larsen | Apparatus for non or minimally disruptive photomanipulation of an eye |
US20080234943A1 (en) * | 2007-03-20 | 2008-09-25 | Pinaki Ray | Computer program for diabetes management |
WO2009064911A2 (en) | 2007-11-13 | 2009-05-22 | The Regents Of The University Of Michigan | Method and apparatus for detecting diseases associated with the eye |
AU2009229348B2 (en) * | 2008-03-27 | 2013-09-19 | Cognoptix, Inc. | Ocular imaging |
CN101485573B (zh) * | 2009-02-12 | 2010-09-29 | 薛萍 | 无创血糖检测监测仪 |
RU2013125754A (ru) | 2010-11-05 | 2014-12-10 | Фридом Медитек, Инк. | Усовершенствованный алгоритм для обнаружения диабета |
-
2011
- 2011-11-07 RU RU2013125754/14A patent/RU2013125754A/ru not_active Application Discontinuation
- 2011-11-07 JP JP2013537921A patent/JP6188225B2/ja active Active
- 2011-11-07 CN CN201180052291.3A patent/CN103188993B/zh active Active
- 2011-11-07 WO PCT/US2011/059653 patent/WO2012061835A2/en active Application Filing
- 2011-11-07 CA CA2813270A patent/CA2813270C/en active Active
- 2011-11-07 WO PCT/US2011/059654 patent/WO2012061836A2/en active Application Filing
- 2011-11-07 CN CN2011800522627A patent/CN103237497A/zh active Pending
- 2011-11-07 KR KR1020137014409A patent/KR101889575B1/ko active IP Right Grant
- 2011-11-07 AU AU2011323111A patent/AU2011323111B2/en active Active
- 2011-11-07 US US13/291,072 patent/US8989848B2/en active Active
- 2011-11-07 JP JP2013537920A patent/JP6012614B2/ja active Active
- 2011-11-07 BR BR112013010015A patent/BR112013010015A2/pt not_active IP Right Cessation
- 2011-11-07 EP EP11838959.2A patent/EP2635186B1/en active Active
- 2011-11-07 TW TW100140642A patent/TWI530272B/zh active
- 2011-11-07 AU AU2011323110A patent/AU2011323110B2/en active Active
- 2011-11-07 TW TW100140644A patent/TWI541003B/zh active
- 2011-11-07 US US13/291,074 patent/US9877647B2/en active Active
- 2011-11-07 BR BR112013010023A patent/BR112013010023A2/pt not_active IP Right Cessation
- 2011-11-07 EP EP11838960.0A patent/EP2635187B1/en active Active
- 2011-11-07 CA CA2813296A patent/CA2813296A1/en not_active Abandoned
-
2013
- 2013-04-04 IL IL225555A patent/IL225555A/en active IP Right Grant
- 2013-04-04 IL IL225554A patent/IL225554A/en active IP Right Grant
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
RU2013125754A (ru) | Усовершенствованный алгоритм для обнаружения диабета | |
Weinreb et al. | Primary open-angle glaucoma | |
Nguyen et al. | Biomechanical contribution of the sclera to dynamic corneal response in air-puff induced deformation in human donor eyes | |
Hong et al. | Development and progression of diabetic retinopathy 12 months after phacoemulsification cataract surgery | |
Bao et al. | Evaluation of the relationship of corneal biomechanical metrics with physical intraocular pressure and central corneal thickness in ex vivo rabbit eye globes | |
Solano et al. | Cataract, phacoemulsification and intraocular pressure: is the anterior segment anatomy the missing piece of the puzzle? | |
Kumar et al. | Effect of prophylactic laser iridotomy on corneal endothelial cell density over 3 years in primary angle closure suspects | |
Beene et al. | Corneal deformation response and ocular geometry: a noninvasive diagnostic strategy in Marfan syndrome | |
Lee et al. | Relationship between ocular pulse amplitude and glaucomatous central visual field defect in normal-tension glaucoma | |
Neuburger et al. | Recovery of corneal hysteresis after reduction of intraocular pressure in chronic primary angle-closure glaucoma | |
Tsai | Optical coherence tomography measurement of retinal nerve fiber layer after acute primary angle closure with normal visual field | |
Gracitelli et al. | Anterior chamber depth during hemodialysis | |
Kanadani et al. | Ocular perfusion pressure and pulsatile ocular blood flow in normal and systemic hypertensive patients | |
Schweitzer et al. | Detection of early metabolic alterations in the ocular fundus of diabetic patients by time-resolved autofluorescence of endogenous fluorophores | |
RU2011120386A (ru) | Способ диагностики первичной открытоугольной глаукомы | |
Bissen-Miyajima et al. | Surface light scattering and visual function of diffractive multifocal hydrophobic acrylic intraocular lenses 6 years after implantation | |
Wray | Acute visual loss | |
Thavikulwat et al. | Longitudinal study of peripapillary thinning in sickle cell hemoglobinopathies | |
Atas et al. | Systemic Endothelial Function in Primary Open‐Angle Glaucoma | |
Mahroo | Electroretinography can provide objective assessment of inner retinal function prior to atrophic change on OCT | |
Apostolova et al. | Features of the Biomechanical Parameters of the Eye Fibrous Membrane and the Index of the Biomechanical Glaucoma Factor in Various Clinical Situations | |
Khanzada et al. | Frequency and types of diabetic maculopathy in type II diabetes | |
Sarkar et al. | Diabetic and hypertensive eye disease, awareness and evolution-a hospital based study in central India | |
RU2465808C1 (ru) | Способ дифференциальной диагностики глаукомы с нормальным давлением и частичной атрофии зрительного нерва на глазах с наличием экскавации диска зрительного нерва | |
Pongpreuksa et al. | Chronic urticaria: What is worth doing in pediatric population? |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20160913 |