RU2012136530A - Новые соединения, влияющие на пищевое поведение - Google Patents
Новые соединения, влияющие на пищевое поведение Download PDFInfo
- Publication number
- RU2012136530A RU2012136530A RU2012136530/10A RU2012136530A RU2012136530A RU 2012136530 A RU2012136530 A RU 2012136530A RU 2012136530/10 A RU2012136530/10 A RU 2012136530/10A RU 2012136530 A RU2012136530 A RU 2012136530A RU 2012136530 A RU2012136530 A RU 2012136530A
- Authority
- RU
- Russia
- Prior art keywords
- haa
- patient
- group
- xaa
- pyy
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title claims abstract 5
- 150000001413 amino acids Chemical group 0.000 claims abstract 8
- 150000003839 salts Chemical class 0.000 claims abstract 6
- 239000012453 solvate Substances 0.000 claims abstract 4
- 244000137850 Marrubium vulgare Species 0.000 claims abstract 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 208000008589 Obesity Diseases 0.000 claims 5
- 230000036528 appetite Effects 0.000 claims 5
- 235000019789 appetite Nutrition 0.000 claims 5
- 235000019577 caloric intake Nutrition 0.000 claims 5
- 235000012631 food intake Nutrition 0.000 claims 5
- 230000037406 food intake Effects 0.000 claims 5
- 235000020824 obesity Nutrition 0.000 claims 5
- 239000008194 pharmaceutical composition Substances 0.000 claims 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- 206010033307 Overweight Diseases 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 238000007920 subcutaneous administration Methods 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 230000004962 physiological condition Effects 0.000 claims 2
- 241000555745 Sciuridae Species 0.000 claims 1
- 230000010933 acylation Effects 0.000 claims 1
- 238000005917 acylation reaction Methods 0.000 claims 1
- 230000009435 amidation Effects 0.000 claims 1
- 238000007112 amidation reaction Methods 0.000 claims 1
- 230000021235 carbamoylation Effects 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 230000004927 fusion Effects 0.000 claims 1
- 230000013595 glycosylation Effects 0.000 claims 1
- 238000006206 glycosylation reaction Methods 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 230000006320 pegylation Effects 0.000 claims 1
- 230000026731 phosphorylation Effects 0.000 claims 1
- 238000006366 phosphorylation reaction Methods 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000010188 recombinant method Methods 0.000 claims 1
- 238000007363 ring formation reaction Methods 0.000 claims 1
- 230000019635 sulfation Effects 0.000 claims 1
- 238000005670 sulfation reaction Methods 0.000 claims 1
- 238000010189 synthetic method Methods 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G23/00—Driving gear for endless conveyors; Belt- or chain-tensioning arrangements
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/57545—Neuropeptide Y
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
- B65G2812/00—Indexing codes relating to the kind or type of conveyors
- B65G2812/02—Belt or chain conveyors
- B65G2812/02267—Conveyors having endless traction elements
- B65G2812/02277—Common features for chain conveyors
- B65G2812/02287—Driving means
- B65G2812/02306—Driving drums
- B65G2812/02316—Driving drums with means for assuring constant linear speed of chains
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Mechanical Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1001333.2 | 2010-01-27 | ||
| GBGB1001333.2A GB201001333D0 (en) | 2010-01-27 | 2010-01-27 | Novel compounds and their effects on feeding behaviour |
| PCT/GB2011/000110 WO2011092473A1 (en) | 2010-01-27 | 2011-01-27 | Novel compounds and their effects on feeding behaviour |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2012136530A true RU2012136530A (ru) | 2014-03-10 |
Family
ID=42084054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2012136530/10A RU2012136530A (ru) | 2010-01-27 | 2011-01-27 | Новые соединения, влияющие на пищевое поведение |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US9018160B2 (OSRAM) |
| EP (1) | EP2528942B1 (OSRAM) |
| JP (1) | JP2013518090A (OSRAM) |
| KR (1) | KR20120127610A (OSRAM) |
| CN (1) | CN102741278A (OSRAM) |
| AU (1) | AU2011210165B2 (OSRAM) |
| BR (1) | BR112012018703A2 (OSRAM) |
| CA (1) | CA2788013A1 (OSRAM) |
| GB (1) | GB201001333D0 (OSRAM) |
| MX (1) | MX2012008792A (OSRAM) |
| RU (1) | RU2012136530A (OSRAM) |
| SG (1) | SG182578A1 (OSRAM) |
| WO (1) | WO2011092473A1 (OSRAM) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11259554B2 (en) | 2015-12-16 | 2022-03-01 | Diet4Life Aps | Dietary peptides |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201101459D0 (en) | 2011-01-27 | 2011-03-16 | Imp Innovations Ltd | Novel compounds and thier effects on fedding behaviour |
| RU2015144632A (ru) * | 2013-05-02 | 2017-06-07 | Глаксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед | Терапевтические пептиды |
| WO2015177572A1 (en) | 2014-05-23 | 2015-11-26 | Imperial Innovations Limited | Peptide yy (pyy) analogues |
| WO2015177573A1 (en) * | 2014-05-23 | 2015-11-26 | Imperial Innovations Limited | Peptide yy (pyy) analogues |
| WO2017021890A1 (en) * | 2015-08-04 | 2017-02-09 | Goal Zero Llc | Portable solar panel system control |
| GB201720188D0 (en) | 2017-12-04 | 2018-01-17 | Imperial Innovations Ltd | Analogues of PYY |
| CN112074286A (zh) | 2018-01-23 | 2020-12-11 | 吉拉毒蜥治疗公司 | 肽yy药物制剂、组合物和方法 |
| GB2573145A (en) * | 2018-04-26 | 2019-10-30 | Univ Ulster | Peptides for metabolic disease |
| GB201908426D0 (en) | 2019-06-12 | 2019-07-24 | Imp College Innovations Ltd | Appetite suppressing compounds |
| US11739134B2 (en) | 2020-04-17 | 2023-08-29 | Intarcia Therapeutics, Inc. | Long acting peptide tyrosine tyrosine (PYY) analogs and methods of use |
| CN114075265B (zh) * | 2020-08-13 | 2025-08-29 | 珠海市丽珠微球科技有限公司 | 一种多肽酪氨酸酪氨酸类似物以及包含其的缓释制剂 |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4179337A (en) | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
| CA1257199A (en) | 1986-05-20 | 1989-07-11 | Paul Y. Wang | Preparation containing bioactive macromolecular substance for multi-months release in vivo |
| IT1243390B (it) | 1990-11-22 | 1994-06-10 | Vectorpharma Int | Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione. |
| CA2123108C (en) | 1991-11-06 | 2003-03-25 | Lisa Selbie | Human neuropeptide y-y1 receptor |
| WO1995005848A1 (en) | 1993-08-24 | 1995-03-02 | Novo Nordisk A/S | Protracted glp-1 |
| US5907030A (en) | 1995-01-25 | 1999-05-25 | University Of Southern California | Method and compositions for lipidization of hydrophilic molecules |
| US5962270A (en) | 1996-02-06 | 1999-10-05 | Bionebraska, Inc. | Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs |
| US6355478B1 (en) | 1996-06-17 | 2002-03-12 | Eli Lilly And Company | Rhesus monkey neuropeptide Y Y2 receptor |
| US6093692A (en) | 1997-09-25 | 2000-07-25 | The University Of Southern California | Method and compositions for lipidization of hydrophilic molecules |
| FR2774674B1 (fr) | 1998-02-10 | 2000-03-24 | Atochem Elf Sa | Procede de preparation d'une solution aqueuse de peroxyde d'hydrogene directement a partir d'hydrogene et d'oxygene et dispositif permettant sa mise en oeuvre |
| US5993414A (en) | 1998-04-23 | 1999-11-30 | Medtronic, Inc. | Implantable device |
| US6436091B1 (en) | 1999-11-16 | 2002-08-20 | Microsolutions, Inc. | Methods and implantable devices and systems for long term delivery of a pharmaceutical agent |
| US6420352B1 (en) | 2000-07-19 | 2002-07-16 | W. Roy Knowles | Hair loss prevention |
| PL205971B1 (pl) | 2001-09-24 | 2010-06-30 | Imp Innovations Ltd | Zastosowanie PYY₃-₃₆ do wytwarzania leku na ograniczanie apetytu, zmniejszenie otyłości lub do zapobiegania otyłości |
| US7186692B2 (en) | 2002-12-17 | 2007-03-06 | Nastech Pharmaceutical Company Inc. | Compositions and methods for enhanced mucosal delivery and non-infused administration of Y2 receptor-binding peptides and methods for treating and preventing obesity |
| EP1718665B1 (en) | 2004-02-11 | 2013-04-10 | Amylin Pharmaceuticals, LLC | Hybrid polypeptides with selectable properties |
| US8076288B2 (en) | 2004-02-11 | 2011-12-13 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides having glucose lowering activity |
| JP5638177B2 (ja) | 2004-02-11 | 2014-12-10 | アミリン・ファーマシューティカルズ, リミテッド・ライアビリティ・カンパニーAmylin Pharmaceuticals, Llc | 膵臓ポリペプチドファミリーモチーフおよびそのモチーフを含むポリペプチド |
| ES2345113T3 (es) | 2004-02-11 | 2010-09-15 | Amylin Pharmaceuticals, Inc. | Peptidos de la familia amilina y metodos para su obtencion y utilizacion. |
| EA011861B1 (ru) | 2004-03-17 | 2009-06-30 | 7ТиЭм ФАРМА А/С | Селективные агонисты рецепторов y2/y4 для терапевтического воздействия |
| BRPI0508935A (pt) | 2004-03-17 | 2007-09-25 | 7Tm Pharmas As | agonistas de receptor seletivo y4 para intervenções terapêuticas |
| CN100425282C (zh) | 2004-03-17 | 2008-10-15 | 7Tm制药联合股份有限公司 | 用于治疗性干预的y2/y4选择性受体激动剂 |
| EP2272524A3 (en) * | 2004-03-17 | 2011-02-02 | 7TM Pharma A/S | Y2 selective receptor agonists for therapeutic interventions |
| US7928060B2 (en) | 2004-10-08 | 2011-04-19 | Amylin Pharmaceuticals, Inc. | Amylin family polypeptide-6 (AFP-6) analogs and methods of making and using them |
| CA2588594C (en) | 2004-12-13 | 2014-02-18 | Amylin Pharmaceuticals, Inc. | Pancreatic polypeptide family motifs, polypeptides and methods comprising the same |
| GB0504857D0 (en) | 2005-03-09 | 2005-04-13 | Imp College Innovations Ltd | Novel compounds and their effects on feeding behaviour |
| JP4629488B2 (ja) | 2005-04-28 | 2011-02-09 | 本田技研工業株式会社 | プラントを制御する制御装置 |
| US20090054326A1 (en) | 2005-07-11 | 2009-02-26 | Nastech Pharmaceutical Company Inc. | Formulations for enhanced mucosal delivery of pyy |
| EP1922336B1 (en) | 2005-08-11 | 2012-11-21 | Amylin Pharmaceuticals, LLC | Hybrid polypeptides with selectable properties |
| CN101296942A (zh) * | 2005-08-11 | 2008-10-29 | 安米林药品公司 | 具有可选择特性的杂合多肽 |
| GB0613196D0 (en) | 2006-07-03 | 2006-08-09 | Imp Innovations Ltd | Novel compounds and their effects on feeding behaviour |
| RU2506273C2 (ru) | 2007-07-09 | 2014-02-10 | Импиэриэл Инноувейшнс Лимитид | Аналог панкреатического полипептида человека (варианты), фармацевтическая композиция на его основе, способ лечения ожирения или диабета, способ снижения аппетита, уменьшения поглощения пищи или снижения потребления калорий и способ косметического снижения массы посредством указанного аналога |
| WO2009042922A2 (en) * | 2007-09-27 | 2009-04-02 | Amylin Pharmaceuticals, Inc. | Peptide-peptidase inhibitor conjugates and methods of making and using same |
| JP2011520847A (ja) * | 2008-05-16 | 2011-07-21 | ノボ・ノルデイスク・エー／エス | 遅効型ｙ２及び／又はｙ４レセプターアゴニスト |
-
2010
- 2010-01-27 GB GBGB1001333.2A patent/GB201001333D0/en not_active Ceased
-
2011
- 2011-01-27 WO PCT/GB2011/000110 patent/WO2011092473A1/en not_active Ceased
- 2011-01-27 CN CN2011800075873A patent/CN102741278A/zh active Pending
- 2011-01-27 AU AU2011210165A patent/AU2011210165B2/en not_active Ceased
- 2011-01-27 JP JP2012550512A patent/JP2013518090A/ja active Pending
- 2011-01-27 US US13/575,133 patent/US9018160B2/en active Active
- 2011-01-27 BR BR112012018703A patent/BR112012018703A2/pt not_active IP Right Cessation
- 2011-01-27 RU RU2012136530/10A patent/RU2012136530A/ru not_active Application Discontinuation
- 2011-01-27 SG SG2012052973A patent/SG182578A1/en unknown
- 2011-01-27 CA CA2788013A patent/CA2788013A1/en not_active Abandoned
- 2011-01-27 MX MX2012008792A patent/MX2012008792A/es not_active Application Discontinuation
- 2011-01-27 KR KR1020127021836A patent/KR20120127610A/ko not_active Withdrawn
- 2011-01-27 EP EP11701543.8A patent/EP2528942B1/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11259554B2 (en) | 2015-12-16 | 2022-03-01 | Diet4Life Aps | Dietary peptides |
| US12295397B2 (en) | 2015-12-16 | 2025-05-13 | Diet4Life Aps | Dietary peptides |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2011210165A1 (en) | 2012-08-23 |
| KR20120127610A (ko) | 2012-11-22 |
| JP2013518090A (ja) | 2013-05-20 |
| BR112012018703A2 (pt) | 2017-01-10 |
| EP2528942A1 (en) | 2012-12-05 |
| EP2528942B1 (en) | 2020-06-17 |
| US20130023464A1 (en) | 2013-01-24 |
| SG182578A1 (en) | 2012-08-30 |
| MX2012008792A (es) | 2012-11-29 |
| WO2011092473A8 (en) | 2012-08-02 |
| CA2788013A1 (en) | 2011-08-04 |
| CN102741278A (zh) | 2012-10-17 |
| WO2011092473A1 (en) | 2011-08-04 |
| AU2011210165B2 (en) | 2014-06-05 |
| GB201001333D0 (en) | 2010-03-17 |
| US9018160B2 (en) | 2015-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA92 | Acknowledgement of application withdrawn (lack of supplementary materials submitted) |
Effective date: 20151125 |