JP2013518090A - 新規化合物及び摂食行動に対するそれらの効果 - Google Patents

新規化合物及び摂食行動に対するそれらの効果 Download PDF

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Publication number
JP2013518090A
JP2013518090A JP2012550512A JP2012550512A JP2013518090A JP 2013518090 A JP2013518090 A JP 2013518090A JP 2012550512 A JP2012550512 A JP 2012550512A JP 2012550512 A JP2012550512 A JP 2012550512A JP 2013518090 A JP2013518090 A JP 2013518090A
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xaa
pyy
group
subject
analog
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JP2012550512A
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Japanese (ja)
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JP2013518090A5 (OSRAM
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スティーブン・ロバート・ブルーム
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インペリアル・イノベイションズ・リミテッド
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Publication of JP2013518090A publication Critical patent/JP2013518090A/ja
Publication of JP2013518090A5 publication Critical patent/JP2013518090A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G23/00Driving gear for endless conveyors; Belt- or chain-tensioning arrangements
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/57545Neuropeptide Y
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65GTRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G2812/00Indexing codes relating to the kind or type of conveyors
    • B65G2812/02Belt or chain conveyors
    • B65G2812/02267Conveyors having endless traction elements
    • B65G2812/02277Common features for chain conveyors
    • B65G2812/02287Driving means
    • B65G2812/02306Driving drums
    • B65G2812/02316Driving drums with means for assuring constant linear speed of chains

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Mechanical Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2012550512A 2010-01-27 2011-01-27 新規化合物及び摂食行動に対するそれらの効果 Pending JP2013518090A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1001333.2 2010-01-27
GBGB1001333.2A GB201001333D0 (en) 2010-01-27 2010-01-27 Novel compounds and their effects on feeding behaviour
PCT/GB2011/000110 WO2011092473A1 (en) 2010-01-27 2011-01-27 Novel compounds and their effects on feeding behaviour

Publications (2)

Publication Number Publication Date
JP2013518090A true JP2013518090A (ja) 2013-05-20
JP2013518090A5 JP2013518090A5 (OSRAM) 2014-03-13

Family

ID=42084054

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012550512A Pending JP2013518090A (ja) 2010-01-27 2011-01-27 新規化合物及び摂食行動に対するそれらの効果

Country Status (13)

Country Link
US (1) US9018160B2 (OSRAM)
EP (1) EP2528942B1 (OSRAM)
JP (1) JP2013518090A (OSRAM)
KR (1) KR20120127610A (OSRAM)
CN (1) CN102741278A (OSRAM)
AU (1) AU2011210165B2 (OSRAM)
BR (1) BR112012018703A2 (OSRAM)
CA (1) CA2788013A1 (OSRAM)
GB (1) GB201001333D0 (OSRAM)
MX (1) MX2012008792A (OSRAM)
RU (1) RU2012136530A (OSRAM)
SG (1) SG182578A1 (OSRAM)
WO (1) WO2011092473A1 (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021505657A (ja) * 2017-12-04 2021-02-18 アイピー2アイピーオー イノベ−ションズ リミテッド Pyy類似体

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201101459D0 (en) 2011-01-27 2011-03-16 Imp Innovations Ltd Novel compounds and thier effects on fedding behaviour
RU2015144632A (ru) * 2013-05-02 2017-06-07 Глаксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Терапевтические пептиды
WO2015177572A1 (en) 2014-05-23 2015-11-26 Imperial Innovations Limited Peptide yy (pyy) analogues
WO2015177573A1 (en) * 2014-05-23 2015-11-26 Imperial Innovations Limited Peptide yy (pyy) analogues
WO2017021890A1 (en) * 2015-08-04 2017-02-09 Goal Zero Llc Portable solar panel system control
WO2017103200A1 (en) 2015-12-16 2017-06-22 Diet4Life Aps Dietary peptides
CN112074286A (zh) 2018-01-23 2020-12-11 吉拉毒蜥治疗公司 肽yy药物制剂、组合物和方法
GB2573145A (en) * 2018-04-26 2019-10-30 Univ Ulster Peptides for metabolic disease
GB201908426D0 (en) 2019-06-12 2019-07-24 Imp College Innovations Ltd Appetite suppressing compounds
US11739134B2 (en) 2020-04-17 2023-08-29 Intarcia Therapeutics, Inc. Long acting peptide tyrosine tyrosine (PYY) analogs and methods of use
CN114075265B (zh) * 2020-08-13 2025-08-29 珠海市丽珠微球科技有限公司 一种多肽酪氨酸酪氨酸类似物以及包含其的缓释制剂

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007531711A (ja) * 2004-02-11 2007-11-08 アミリン・ファーマシューティカルズ,インコーポレイテッド 膵臓ポリペプチドファミリーモチーフおよびそのモチーフを含むポリペプチド
JP2007531713A (ja) * 2004-03-17 2007-11-08 7ティーエム ファーマ エイ/エス 治療的介入のためのy2選択性レセプターアゴニスト
JP2008534435A (ja) * 2004-12-13 2008-08-28 アミリン・ファーマシューティカルズ,インコーポレイテッド 膵臓ポリペプチドファミリーモチーフ、ポリペプチドおよびこれらを含む方法
JP2009504681A (ja) * 2005-08-11 2009-02-05 アミリン・ファーマシューティカルズ,インコーポレイテッド 選択可能な特性を有するハイブリッドポリペプチド
WO2009042922A2 (en) * 2007-09-27 2009-04-02 Amylin Pharmaceuticals, Inc. Peptide-peptidase inhibitor conjugates and methods of making and using same
WO2009138511A1 (en) * 2008-05-16 2009-11-19 Novo Nordisk A/S Long-acting y2 and/or y4 receptor agonists

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
CA1257199A (en) 1986-05-20 1989-07-11 Paul Y. Wang Preparation containing bioactive macromolecular substance for multi-months release in vivo
IT1243390B (it) 1990-11-22 1994-06-10 Vectorpharma Int Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione.
CA2123108C (en) 1991-11-06 2003-03-25 Lisa Selbie Human neuropeptide y-y1 receptor
WO1995005848A1 (en) 1993-08-24 1995-03-02 Novo Nordisk A/S Protracted glp-1
US5907030A (en) 1995-01-25 1999-05-25 University Of Southern California Method and compositions for lipidization of hydrophilic molecules
US5962270A (en) 1996-02-06 1999-10-05 Bionebraska, Inc. Recombinant preparation of calcitonin fragments and use thereof in the preparation of calcitonin and related analogs
US6355478B1 (en) 1996-06-17 2002-03-12 Eli Lilly And Company Rhesus monkey neuropeptide Y Y2 receptor
US6093692A (en) 1997-09-25 2000-07-25 The University Of Southern California Method and compositions for lipidization of hydrophilic molecules
FR2774674B1 (fr) 1998-02-10 2000-03-24 Atochem Elf Sa Procede de preparation d'une solution aqueuse de peroxyde d'hydrogene directement a partir d'hydrogene et d'oxygene et dispositif permettant sa mise en oeuvre
US5993414A (en) 1998-04-23 1999-11-30 Medtronic, Inc. Implantable device
US6436091B1 (en) 1999-11-16 2002-08-20 Microsolutions, Inc. Methods and implantable devices and systems for long term delivery of a pharmaceutical agent
US6420352B1 (en) 2000-07-19 2002-07-16 W. Roy Knowles Hair loss prevention
PL205971B1 (pl) 2001-09-24 2010-06-30 Imp Innovations Ltd Zastosowanie PYY₃-₃₆ do wytwarzania leku na ograniczanie apetytu, zmniejszenie otyłości lub do zapobiegania otyłości
US7186692B2 (en) 2002-12-17 2007-03-06 Nastech Pharmaceutical Company Inc. Compositions and methods for enhanced mucosal delivery and non-infused administration of Y2 receptor-binding peptides and methods for treating and preventing obesity
EP1718665B1 (en) 2004-02-11 2013-04-10 Amylin Pharmaceuticals, LLC Hybrid polypeptides with selectable properties
US8076288B2 (en) 2004-02-11 2011-12-13 Amylin Pharmaceuticals, Inc. Hybrid polypeptides having glucose lowering activity
ES2345113T3 (es) 2004-02-11 2010-09-15 Amylin Pharmaceuticals, Inc. Peptidos de la familia amilina y metodos para su obtencion y utilizacion.
EA011861B1 (ru) 2004-03-17 2009-06-30 7ТиЭм ФАРМА А/С Селективные агонисты рецепторов y2/y4 для терапевтического воздействия
BRPI0508935A (pt) 2004-03-17 2007-09-25 7Tm Pharmas As agonistas de receptor seletivo y4 para intervenções terapêuticas
CN100425282C (zh) 2004-03-17 2008-10-15 7Tm制药联合股份有限公司 用于治疗性干预的y2/y4选择性受体激动剂
US7928060B2 (en) 2004-10-08 2011-04-19 Amylin Pharmaceuticals, Inc. Amylin family polypeptide-6 (AFP-6) analogs and methods of making and using them
GB0504857D0 (en) 2005-03-09 2005-04-13 Imp College Innovations Ltd Novel compounds and their effects on feeding behaviour
JP4629488B2 (ja) 2005-04-28 2011-02-09 本田技研工業株式会社 プラントを制御する制御装置
US20090054326A1 (en) 2005-07-11 2009-02-26 Nastech Pharmaceutical Company Inc. Formulations for enhanced mucosal delivery of pyy
EP1922336B1 (en) 2005-08-11 2012-11-21 Amylin Pharmaceuticals, LLC Hybrid polypeptides with selectable properties
GB0613196D0 (en) 2006-07-03 2006-08-09 Imp Innovations Ltd Novel compounds and their effects on feeding behaviour
RU2506273C2 (ru) 2007-07-09 2014-02-10 Импиэриэл Инноувейшнс Лимитид Аналог панкреатического полипептида человека (варианты), фармацевтическая композиция на его основе, способ лечения ожирения или диабета, способ снижения аппетита, уменьшения поглощения пищи или снижения потребления калорий и способ косметического снижения массы посредством указанного аналога

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007531711A (ja) * 2004-02-11 2007-11-08 アミリン・ファーマシューティカルズ,インコーポレイテッド 膵臓ポリペプチドファミリーモチーフおよびそのモチーフを含むポリペプチド
JP2007531713A (ja) * 2004-03-17 2007-11-08 7ティーエム ファーマ エイ/エス 治療的介入のためのy2選択性レセプターアゴニスト
JP2008534435A (ja) * 2004-12-13 2008-08-28 アミリン・ファーマシューティカルズ,インコーポレイテッド 膵臓ポリペプチドファミリーモチーフ、ポリペプチドおよびこれらを含む方法
JP2009504681A (ja) * 2005-08-11 2009-02-05 アミリン・ファーマシューティカルズ,インコーポレイテッド 選択可能な特性を有するハイブリッドポリペプチド
WO2009042922A2 (en) * 2007-09-27 2009-04-02 Amylin Pharmaceuticals, Inc. Peptide-peptidase inhibitor conjugates and methods of making and using same
WO2009138511A1 (en) * 2008-05-16 2009-11-19 Novo Nordisk A/S Long-acting y2 and/or y4 receptor agonists

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021505657A (ja) * 2017-12-04 2021-02-18 アイピー2アイピーオー イノベ−ションズ リミテッド Pyy類似体
JP7539835B2 (ja) 2017-12-04 2024-08-26 アイピー2アイピーオー イノベ-ションズ リミテッド Pyy類似体

Also Published As

Publication number Publication date
RU2012136530A (ru) 2014-03-10
AU2011210165A1 (en) 2012-08-23
KR20120127610A (ko) 2012-11-22
BR112012018703A2 (pt) 2017-01-10
EP2528942A1 (en) 2012-12-05
EP2528942B1 (en) 2020-06-17
US20130023464A1 (en) 2013-01-24
SG182578A1 (en) 2012-08-30
MX2012008792A (es) 2012-11-29
WO2011092473A8 (en) 2012-08-02
CA2788013A1 (en) 2011-08-04
CN102741278A (zh) 2012-10-17
WO2011092473A1 (en) 2011-08-04
AU2011210165B2 (en) 2014-06-05
GB201001333D0 (en) 2010-03-17
US9018160B2 (en) 2015-04-28

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