RU2010100893A - Производные 4-(n-азациклоалкил) анилидов как модуляторы калиевых каналов - Google Patents

Производные 4-(n-азациклоалкил) анилидов как модуляторы калиевых каналов Download PDF

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Publication number
RU2010100893A
RU2010100893A RU2010100893/04A RU2010100893A RU2010100893A RU 2010100893 A RU2010100893 A RU 2010100893A RU 2010100893/04 A RU2010100893/04 A RU 2010100893/04A RU 2010100893 A RU2010100893 A RU 2010100893A RU 2010100893 A RU2010100893 A RU 2010100893A
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compound
alkyl
halogen
methyl
independently
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RU2010100893/04A
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English (en)
Russian (ru)
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Жан-Мишель ВЕРНЬЕ (US)
Жан-Мишель Вернье
Самеди ОУК (US)
Самеди Оук
ЛА РОСА Марта Алисия ДЕ (US)
ЛА РОСА Марта Алисия ДЕ
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Валеант Фармасьютикалс Интернэшнл (Us)
Валеант Фармасьютикалс Интернэшнл
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Publication of RU2010100893A publication Critical patent/RU2010100893A/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
RU2010100893/04A 2007-06-13 2008-06-13 Производные 4-(n-азациклоалкил) анилидов как модуляторы калиевых каналов RU2010100893A (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US93439607P 2007-06-13 2007-06-13
US60/934,396 2007-06-13
US12/138,251 US8367684B2 (en) 2007-06-13 2008-06-12 Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
US12/138,251 2008-06-12

Publications (1)

Publication Number Publication Date
RU2010100893A true RU2010100893A (ru) 2011-07-20

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU2010100893/04A RU2010100893A (ru) 2007-06-13 2008-06-13 Производные 4-(n-азациклоалкил) анилидов как модуляторы калиевых каналов

Country Status (18)

Country Link
US (1) US8367684B2 (online.php)
EP (1) EP2170861B1 (online.php)
JP (1) JP2010530002A (online.php)
KR (1) KR20100018618A (online.php)
CN (1) CN101868451A (online.php)
AU (1) AU2008266009B2 (online.php)
BR (1) BRPI0812564A2 (online.php)
CA (1) CA2689208A1 (online.php)
DK (1) DK2170861T3 (online.php)
ES (1) ES2392774T3 (online.php)
HR (1) HRP20120857T1 (online.php)
MX (1) MX2009013581A (online.php)
PL (1) PL2170861T3 (online.php)
PT (1) PT2170861E (online.php)
RU (1) RU2010100893A (online.php)
SI (1) SI2170861T1 (online.php)
TW (1) TW200914452A (online.php)
WO (1) WO2008157404A2 (online.php)

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JP5763758B2 (ja) * 2010-07-08 2015-08-12 ファイザー・インク Ｋｖ７カリウムチャネル開口薬としてのピペリジニルピリミジンアミド
BR112014025201A2 (pt) 2012-04-10 2017-07-11 Sumitomo Dainippon Pharma Co Ltd derivado de indazol 1-substituído
CN108250128A (zh) * 2012-09-27 2018-07-06 江苏先声药业有限公司 作为钾通道调节剂的化合物
CN107835649B (zh) 2015-07-07 2021-03-23 高露洁-棕榄公司 口腔护理器具和用于口腔护理器具的单丝刷毛
CN110511220B (zh) 2018-05-22 2022-04-01 上海挚盟医药科技有限公司 作为钾通道调节剂的对二氨基苯衍生物、其制备方法及其在医药上的应用
WO2023125935A1 (zh) * 2021-12-31 2023-07-06 上海翰森生物医药科技有限公司 苯并哌啶衍生物调节剂、其制备方法和应用
CN116535353A (zh) * 2022-01-25 2023-08-04 上海挚盟医药科技有限公司 作为钾通道调节剂的酰胺类化合物及其制备和应用

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Also Published As

Publication number Publication date
CA2689208A1 (en) 2008-12-24
US8367684B2 (en) 2013-02-05
ES2392774T3 (es) 2012-12-13
HRP20120857T1 (hr) 2012-11-30
MX2009013581A (es) 2010-01-26
PT2170861E (pt) 2012-09-06
BRPI0812564A2 (pt) 2015-02-10
PL2170861T3 (pl) 2013-01-31
AU2008266009A1 (en) 2008-12-24
DK2170861T3 (da) 2012-11-26
SI2170861T1 (sl) 2012-12-31
CN101868451A (zh) 2010-10-20
EP2170861A2 (en) 2010-04-07
TW200914452A (en) 2009-04-01
EP2170861B1 (en) 2012-08-29
KR20100018618A (ko) 2010-02-17
US20080318979A1 (en) 2008-12-25
JP2010530002A (ja) 2010-09-02
WO2008157404A3 (en) 2009-02-19
AU2008266009B2 (en) 2013-06-06
WO2008157404A2 (en) 2008-12-24

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