BRPI0812564A2 - Derivados de 4-(n-azacicloalquil) anilidas como moduladores de canal de potássio - Google Patents
Derivados de 4-(n-azacicloalquil) anilidas como moduladores de canal de potássioInfo
- Publication number
- BRPI0812564A2 BRPI0812564A2 BRPI0812564-3A2A BRPI0812564A BRPI0812564A2 BR PI0812564 A2 BRPI0812564 A2 BR PI0812564A2 BR PI0812564 A BRPI0812564 A BR PI0812564A BR PI0812564 A2 BRPI0812564 A2 BR PI0812564A2
- Authority
- BR
- Brazil
- Prior art keywords
- azacycloalkyl
- potassium channel
- channel modulators
- anilide derivatives
- anilide
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93439607P | 2007-06-13 | 2007-06-13 | |
US12/138,251 US8367684B2 (en) | 2007-06-13 | 2008-06-12 | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
PCT/US2008/066984 WO2008157404A2 (en) | 2007-06-13 | 2008-06-13 | Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0812564A2 true BRPI0812564A2 (pt) | 2015-02-10 |
Family
ID=40137141
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0812564-3A2A BRPI0812564A2 (pt) | 2007-06-13 | 2008-06-13 | Derivados de 4-(n-azacicloalquil) anilidas como moduladores de canal de potássio |
Country Status (18)
Country | Link |
---|---|
US (1) | US8367684B2 (pt) |
EP (1) | EP2170861B1 (pt) |
JP (1) | JP2010530002A (pt) |
KR (1) | KR20100018618A (pt) |
CN (1) | CN101868451A (pt) |
AU (1) | AU2008266009B2 (pt) |
BR (1) | BRPI0812564A2 (pt) |
CA (1) | CA2689208A1 (pt) |
DK (1) | DK2170861T3 (pt) |
ES (1) | ES2392774T3 (pt) |
HR (1) | HRP20120857T1 (pt) |
MX (1) | MX2009013581A (pt) |
PL (1) | PL2170861T3 (pt) |
PT (1) | PT2170861E (pt) |
RU (1) | RU2010100893A (pt) |
SI (1) | SI2170861T1 (pt) |
TW (1) | TW200914452A (pt) |
WO (1) | WO2008157404A2 (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8563566B2 (en) * | 2007-08-01 | 2013-10-22 | Valeant Pharmaceuticals International | Naphthyridine derivatives as potassium channel modulators |
US7786146B2 (en) * | 2007-08-13 | 2010-08-31 | Valeant Pharmaceuticals International | Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators |
WO2010122064A1 (en) | 2009-04-21 | 2010-10-28 | Neurosearch A/S | Substituted naphthyridine derivatives and their medical use |
SG186409A1 (en) * | 2010-07-08 | 2013-02-28 | Pfizer | Piperidinyl pyrimidine amides as kv7 potassium channel openers |
US9309221B2 (en) | 2012-04-10 | 2016-04-12 | Sumitomo Dainippon Pharma Co., Ltd. | 1-substituted indazole derivative |
CN103694163A (zh) * | 2012-09-27 | 2014-04-02 | 上海先声药物研究有限公司 | 作为钾通道调节剂的化合物 |
MX2018000271A (es) | 2015-07-07 | 2018-04-11 | Colgate Palmolive Co | Implemento de cuidado oral y cerda monofilamento para usar con este. |
CN110511220B (zh) * | 2018-05-22 | 2022-04-01 | 上海挚盟医药科技有限公司 | 作为钾通道调节剂的对二氨基苯衍生物、其制备方法及其在医药上的应用 |
WO2023125935A1 (zh) * | 2021-12-31 | 2023-07-06 | 上海翰森生物医药科技有限公司 | 苯并哌啶衍生物调节剂、其制备方法和应用 |
CN116535353A (zh) * | 2022-01-25 | 2023-08-04 | 上海挚盟医药科技有限公司 | 作为钾通道调节剂的酰胺类化合物及其制备和应用 |
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-
2008
- 2008-06-12 US US12/138,251 patent/US8367684B2/en active Active
- 2008-06-13 KR KR1020107000706A patent/KR20100018618A/ko not_active Application Discontinuation
- 2008-06-13 ES ES08771077T patent/ES2392774T3/es active Active
- 2008-06-13 PL PL08771077T patent/PL2170861T3/pl unknown
- 2008-06-13 RU RU2010100893/04A patent/RU2010100893A/ru not_active Application Discontinuation
- 2008-06-13 CA CA002689208A patent/CA2689208A1/en not_active Abandoned
- 2008-06-13 JP JP2010512399A patent/JP2010530002A/ja active Pending
- 2008-06-13 BR BRPI0812564-3A2A patent/BRPI0812564A2/pt not_active Application Discontinuation
- 2008-06-13 TW TW097122339A patent/TW200914452A/zh unknown
- 2008-06-13 PT PT08771077T patent/PT2170861E/pt unknown
- 2008-06-13 EP EP08771077A patent/EP2170861B1/en not_active Not-in-force
- 2008-06-13 DK DK08771077.8T patent/DK2170861T3/da active
- 2008-06-13 SI SI200830745T patent/SI2170861T1/sl unknown
- 2008-06-13 WO PCT/US2008/066984 patent/WO2008157404A2/en active Application Filing
- 2008-06-13 CN CN200880102338A patent/CN101868451A/zh active Pending
- 2008-06-13 AU AU2008266009A patent/AU2008266009B2/en not_active Ceased
- 2008-06-13 MX MX2009013581A patent/MX2009013581A/es active IP Right Grant
-
2012
- 2012-10-23 HR HRP20120857AT patent/HRP20120857T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
ES2392774T3 (es) | 2012-12-13 |
CA2689208A1 (en) | 2008-12-24 |
SI2170861T1 (sl) | 2012-12-31 |
US8367684B2 (en) | 2013-02-05 |
RU2010100893A (ru) | 2011-07-20 |
WO2008157404A3 (en) | 2009-02-19 |
TW200914452A (en) | 2009-04-01 |
HRP20120857T1 (hr) | 2012-11-30 |
KR20100018618A (ko) | 2010-02-17 |
WO2008157404A2 (en) | 2008-12-24 |
EP2170861A2 (en) | 2010-04-07 |
MX2009013581A (es) | 2010-01-26 |
PT2170861E (pt) | 2012-09-06 |
PL2170861T3 (pl) | 2013-01-31 |
EP2170861B1 (en) | 2012-08-29 |
CN101868451A (zh) | 2010-10-20 |
JP2010530002A (ja) | 2010-09-02 |
AU2008266009A1 (en) | 2008-12-24 |
DK2170861T3 (da) | 2012-11-26 |
US20080318979A1 (en) | 2008-12-25 |
AU2008266009B2 (en) | 2013-06-06 |
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