IN188411B - - Google Patents

Info

Publication number
IN188411B
IN188411B IN724DE1998A IN188411B IN 188411 B IN188411 B IN 188411B IN 724DE1998 A IN724DE1998 A IN 724DE1998A IN 188411 B IN188411 B IN 188411B
Authority
IN
India
Application number
Other languages
English (en)
Inventor
Wook Lee-Korea Jong
Young Lee-Korea Bong
Seop Kim-Korea Chang
Kyu Lee-Korea Seung
Seog Song-Korea Keun
Jin Lee-Korea Song
Jeon Shim-Korea Woo
Soon Hwang-Korea Man
Original Assignee
Yuhan Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yuhan Corp filed Critical Yuhan Corp
Publication of IN188411B publication Critical patent/IN188411B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
IN724DE1998 1997-03-27 1998-03-23 IN188411B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR19970010862 1997-03-27
KR19970010863 1997-03-27

Publications (1)

Publication Number Publication Date
IN188411B true IN188411B (pt) 2002-09-21

Family

ID=26632616

Family Applications (1)

Application Number Title Priority Date Filing Date
IN724DE1998 IN188411B (pt) 1997-03-27 1998-03-23

Country Status (22)

Country Link
US (1) US6352993B1 (pt)
EP (1) EP1015444B1 (pt)
JP (1) JP3176379B2 (pt)
KR (1) KR100278857B1 (pt)
CN (1) CN1118464C (pt)
AR (1) AR012181A1 (pt)
AT (1) ATE241613T1 (pt)
AU (1) AU720385B2 (pt)
BR (1) BR9808070A (pt)
CA (1) CA2284795C (pt)
DE (1) DE69815126T2 (pt)
DK (1) DK1015444T3 (pt)
ES (1) ES2200324T3 (pt)
HK (1) HK1026418A1 (pt)
HU (1) HUP0000851A3 (pt)
IN (1) IN188411B (pt)
PT (1) PT1015444E (pt)
RU (1) RU2203894C2 (pt)
TR (1) TR199902383T2 (pt)
TW (1) TW542831B (pt)
UY (1) UY24938A1 (pt)
WO (1) WO1998043968A1 (pt)

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KR100272471B1 (ko) 1998-11-17 2000-11-15 김선진 신규의 피리미딘 유도체 및 그의 제조방법
US6852739B1 (en) 1999-02-26 2005-02-08 Nitromed Inc. Methods using proton pump inhibitors and nitric oxide donors
TW200302728A (en) 2002-02-01 2003-08-16 Novartis Ag Substituted amines as IgE inhibitors
EP1534278A4 (en) 2002-08-01 2006-09-06 Nitromed Inc NITROSED PROTONATE PUMP INHIBITORS, COMPOSITIONS AND USE METHOD
WO2005009980A1 (en) * 2003-07-22 2005-02-03 Neurogen Corporation Substituted pyridin-2-ylamine analogues
CA2541989C (en) * 2003-10-24 2013-10-01 Exelixis, Inc. P70s6 kinase modulators and method of use
CN101361738A (zh) 2003-11-03 2009-02-11 阿斯利康(瑞典)有限公司 治疗隐匿性胃食管反流的咪唑并[1,2-a]吡啶衍生物
KR101122376B1 (ko) * 2005-03-09 2012-03-26 주식회사유한양행 신규의 5,6-다이메틸피리미딘 유도체 및 그의 제조방법
EP1940804A2 (en) * 2005-10-14 2008-07-09 NeuroSearch A/S Novel pyrimidine-2,4-diamine derivatives and their use as modulators of small-conductance calcium-activated potassium channels
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
DK2308877T3 (da) 2008-08-05 2014-04-22 Daiichi Sankyo Co Ltd Imidazopyridin-2-on-derivater
GB0908394D0 (en) 2009-05-15 2009-06-24 Univ Leuven Kath Novel viral replication inhibitors
GB0913636D0 (en) 2009-08-05 2009-09-16 Univ Leuven Kath Novel viral replication inhibitors
US9132129B2 (en) 2010-11-15 2015-09-15 Katholieke Universiteit Leuven Antiviral compounds
AU2012221925B2 (en) 2011-02-25 2016-05-05 Yuhan Corporation Diaminopyrimidine derivatives and processes for the preparation thereof
CN104203939B (zh) * 2012-02-17 2017-06-06 艾伯维公司 用作人呼吸道合胞病毒(rsv)抑制剂的二氨基嘧啶
US9309271B2 (en) 2012-05-29 2016-04-12 Momentive Performance Materials Gmbh Preparation of isocyanato silanes
US10428050B2 (en) 2012-11-21 2019-10-01 Ptc Therapeutics, Inc. Substituted reverse pyrimidine Bmi-1 inhibitors
WO2014139326A1 (en) 2013-03-13 2014-09-18 Genentech, Inc. Pyrazolo compounds and uses thereof
AR093580A1 (es) * 2013-08-30 2015-06-10 Ptc Therapeutics Inc Inhibidores bmi-1 de pirimidina sustituidos
ES2779152T3 (es) * 2013-10-07 2020-08-13 Kadmon Corporation Llc Derivados de (2-(5-isoindolin-2-il)pirimidin-4-il)-amina como inhibidores de Rho-quinasa para tratar enfermedades autoinmunes
US10584115B2 (en) 2013-11-21 2020-03-10 Ptc Therapeutics, Inc. Substituted pyridine and pyrazine BMI-1 inhibitors
CA2965336A1 (en) 2014-10-22 2016-04-28 The Board Of Regents Of The University Of Texas System Small-molecule inhibitors targeting discoidin domain receptor 1 and uses thereof
CN105669642B (zh) * 2014-11-19 2020-06-09 江苏天士力帝益药业有限公司 一种盐酸洛氟普啶的制备方法
AU2017205670B2 (en) * 2016-01-04 2021-05-20 Merck Serono S.A. L-valinate of hydroxypropylthiazolidine carboxamide derivative and salt form, crystal polymorph thereof
EP3606915A1 (de) * 2017-04-05 2020-02-12 Bayer CropScience Aktiengesellschaft 2-amino-5-oxyalkyl-pyrimidinderivate und deren verwendung zur bekämpfung unerwünschten pflanzenwachstums
WO2020055544A2 (en) 2018-08-17 2020-03-19 Ptc Therapeutics, Inc. Method for treating pancreatic cancer
CN114685369B (zh) * 2022-05-17 2024-02-02 河南省科学院高新技术研究中心 一种利用离子液体制备1-甲基-1,2,3,4-四氢异喹啉的方法

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GB1182584A (en) 1966-03-31 1970-02-25 Ici Ltd Pyrimidine derivates and the use thereof as fungicides
US3980781A (en) 1966-03-31 1976-09-14 Imperial Chemical Industries Limited Fungicidal composition and method containing 2-amino-pyrimidines
US4000138A (en) 1966-03-31 1976-12-28 Imperial Chemical Industries Limited Organic compounds and compositions containing them
US4044136A (en) 1972-09-09 1977-08-23 Pfizer Inc. Aminoquinazoline therapeutic agents
GB1383409A (en) 1972-09-09 1974-02-12 Pfizer Ltd Derivatives of 2-amino- and 4-amino-quinazoline and pharmaceutical compositions containing them
US3956495A (en) 1973-10-30 1976-05-11 Eli Lilly And Company 2,4-Diaminoquinazolines as antithrombotic agents
US4755218A (en) 1985-12-31 1988-07-05 Monsanto Company Haloacyl 1-substituted-1,2,3,4-tetrahydro-isoquinolines as herbicide antidotes
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
IL88507A (en) * 1987-12-03 1993-02-21 Smithkline Beckman Intercredit 2,4-diaminoquinazolines, process for their preparation and pharmaceutical compositions comprising them
US4966622A (en) 1988-04-12 1990-10-30 Ciba-Geigy Corporation N-phenyl-N-pyrimidin-2-ylureas
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
DE3901448A1 (de) 1989-01-19 1990-07-26 Basf Ag Emulsionscopolymerisate
DE59010042D1 (de) 1989-03-22 1996-02-22 Ciba Geigy Ag Schädlingsbekämpfungsmittel
CA2015981A1 (en) * 1989-05-10 1990-11-10 Thomas H. Brown Compounds
GB8910722D0 (en) 1989-05-10 1989-06-28 Smithkline Beckman Intercredit Compounds
GB9012592D0 (en) 1990-06-06 1990-07-25 Smithkline Beecham Intercredit Compounds
DE69111077T2 (de) 1990-11-06 1995-11-02 Pfizer Chinazolinderivate um die antitumorwirkung zu verbessern.
JPH0819121B2 (ja) 1991-04-17 1996-02-28 フアイザー・インコーポレイテツド 抗腫瘍活性を増強するためのピリミジン誘導体
US5276186A (en) 1992-03-11 1994-01-04 Ciba-Geigy Corporation Process for the production of guanidine derivatives
KR0144833B1 (ko) * 1992-12-28 1998-07-15 김태훈 신규의 퀴나졸린 유도체 및 그의 제조방법
DK0640599T3 (da) 1993-08-26 1998-09-28 Ono Pharmaceutical Co 4-Aminopyrimidin-derivater
WO1995010506A1 (en) 1993-10-12 1995-04-20 The Du Pont Merck Pharmaceutical Company 1n-alkyl-n-arylpyrimidinamines and derivatives thereof
EP0775120B1 (en) * 1994-08-13 2003-06-04 Yuhan Corporation Novel pyrimidine derivatives and processes for the preparation thereof
EP0900214B1 (en) 1996-05-04 2001-09-26 Yuhan Corporation Process for preparation of pyrimidine derivatives

Also Published As

Publication number Publication date
AR012181A1 (es) 2000-09-27
PT1015444E (pt) 2003-10-31
RU2203894C2 (ru) 2003-05-10
TW542831B (en) 2003-07-21
CN1251586A (zh) 2000-04-26
KR19980080789A (ko) 1998-11-25
WO1998043968A1 (en) 1998-10-08
HK1026418A1 (en) 2000-12-15
HUP0000851A1 (hu) 2001-04-28
US6352993B1 (en) 2002-03-05
EP1015444A1 (en) 2000-07-05
JP2000513014A (ja) 2000-10-03
DE69815126D1 (de) 2003-07-03
DE69815126T2 (de) 2004-04-08
CA2284795A1 (en) 1998-10-08
KR100278857B1 (ko) 2001-01-15
ATE241613T1 (de) 2003-06-15
DK1015444T3 (da) 2003-08-18
ES2200324T3 (es) 2004-03-01
TR199902383T2 (xx) 2000-06-21
HUP0000851A3 (en) 2002-04-29
UY24938A1 (es) 2001-01-31
CA2284795C (en) 2004-01-20
AU6523998A (en) 1998-10-22
EP1015444B1 (en) 2003-05-28
BR9808070A (pt) 2000-03-08
AU720385B2 (en) 2000-06-01
CN1118464C (zh) 2003-08-20
JP3176379B2 (ja) 2001-06-18

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